susan candradewi | Universitas ahmad dahlan (original) (raw)
Papers by susan candradewi
Journal of Advanced Pharmacy Education and Research
Asian Pacific Journal of Cancer Prevention
Objective: This study aims to develop a mapping algorithm for EORTC QLQ-C30 to EQ-5D-5L which can... more Objective: This study aims to develop a mapping algorithm for EORTC QLQ-C30 to EQ-5D-5L which can produce utility values in patients with cancer. Methods: We used a cross sectional study design with 300 cancer patients. The research instruments used were EORTC QLQ-C30 and EQ-5D-5L. Data were collected by interviewing cancer patients who were hospitalized in the Kasuari Installation of Dr Kariadi Hospital Semarang, Indonesia. The Ordinary Least Squares (OLS) regression method was used to predict the utility value of EQ-5D-5L. This study uses two models to predict utility values, namely model 1 with all domains, and model 2 with domains that affect the EQ-5D-5L. The predictive power of regression on the model is evaluated by calculating the mean absolute error (MAE) and root mean square error (RMSE) values. Result: The highest score in the functional domain is the 'emotional function' domain (mean: 85.89; SD: 16.04) and the highest symptom domain is 'weakness' (mean: 36.21; SD:21.69). The predicted utility values of models 1 and 2 are 0.683. The mean absolute error (MAE) and root mean square error (RMSE) values of model 1 are 0.128 and 0.173, while in model 2 the MAE and RMSE values obtained are 0.125 and 0.168. Conclusion: The development of the mapping algorithm from the EORTC QLQ-C30 to EQ-5D-5L instrument shows a predictive value of utility in a sample of patients with cancer at Dr. Kariadi Hospital, Semarang, Indonesia. The utility prediction in both model is similar, however model 2 involves fewer domains and symptoms.
International Journal of Clinical Practice
One of the important outcomes to define the success of cancer treatment is the health-related qua... more One of the important outcomes to define the success of cancer treatment is the health-related quality of life (HRQoL) that can be measured using generic and/or specific instruments. Our study aims to define the cancer patients’ HRQoL in some hospitals in Indonesia as measured by the European Organization for Research and Treatment for Cancer (EORTC QLQ-C30) and the EQ-5D-5L, to define the differences of cancer patients’ HRQoL referring to patients’ characteristics, and to explore determinants of cancer patients’ HRQoL. We recruited 451 cancer patients using a cross-sectional design in two referral hospitals in Central Java, Indonesia, using the purposive sampling technique. All subjects, recruited from July 2020 to October 2021, met the inclusion criteria, namely, adult patients diagnosed with cancers in all stages who willingly participated in the study. The Indonesian value set was used to obtain the EQ-5D-5L index score. We further analyzed the data based on cancer stages and com...
Jurnal Farmasi Udayana
Virus Corona yang ditemukan di Wuhan memberikan tantangan dikalangan petugas kesehatan seperti ap... more Virus Corona yang ditemukan di Wuhan memberikan tantangan dikalangan petugas kesehatan seperti apoteker yang bertanggung jawab memberikan edukasi kepada masyarakat khususnya terhadap COVID 19. Penelitian ini bertujuan untuk mengukur tingkat pengetahuan, persepsi dan sikap apoteker di apotek Kota Yogyakarta mengenai COVID-19. Desain penelitian adalah observasional analitik dengan populasi apoteker yang berpraktik di apotek Kota Yogyakarta dan sampel penelitian apoteker yang berpraktik di apotek minimal 6 bulan. Hasil penelitian menunjukkan apoteker di apotek kota Yogyakarta memiliki pengetahuan baik mengenai COVID-19 (60%) dan 40% apoteker memiliki pengetahuan yang cukup. Apoteker memiliki persepsi positif sebanyak 66% dan persepsi negatif sebanyak 34% Sikap apoteker menunjukkan 68% positif dan dan 32% negatif. Hubungan tingkat pendidikan dengan pengetahuan, persepsi dan sikap apoteker diperoleh nilai p berturut-turut 0.241, 0.806 dan 0.094, sedangkan hubungan lama pengalaman beker...
Journal Syifa Sciences and Clinical Research, Feb 12, 2022
Swamedikasi merupakan salah satu upaya yang paling banyak dilakukan oleh seseorang dalam mengatas... more Swamedikasi merupakan salah satu upaya yang paling banyak dilakukan oleh seseorang dalam mengatasi gejala sakit ringan yang sedang dideritanya sebelum melakukan konsultasi kepada tenaga kesehatan. Hasil Survei Sosial Ekonomi Nasional (Susenas) tahun 2014 menunjukkan bahwa presentase penduduk yang memilih swamedikasi atau pengobatan diri sendiri akibat keluhan kesehatan yang dialami sebesar 61,05%. Banyak faktor yang mempengaruhi masyarakat untuk melakukan pengobatan, salah satunya adalah iklan. Tujuan penelitian untuk mengetahui hubungan antara pengaruh iklan obat terhadap keputusan pemilihan obat serta ketepatan tindakan swamedikasi pada masyarakat di Kecamatan Umbulharjo Kota Yogyakarta. Desain penelitian ini adalah observasional analitik dengan pengambilan data secara cross-sectional. Teknik pengambilan sampel menggunakan metode insidental sampling dan data dikumpulkan melalui pengisian kuesioner yang telah divalidasi. Analisis data dilakukan dengan uji univariate dan bivariate dengan menggunakan SPSS 20.0. Hasil penelitian menunjukkan bahwa hasil uji signifikansi antara pengaruh iklan obat di televise terhadap ketepatan tindakan swamedikasi adalah 0,864. Kesimpulan pada penelitian ini bahwa iklan tidak memiliki pengaruh terhadap ketepatan tindakan swamedikasi masyarakat (p> 0,05).
KnE Medicine
48.9% of pregnant women in Indonesia in 2018 had anemia. This can affect the health and quality o... more 48.9% of pregnant women in Indonesia in 2018 had anemia. This can affect the health and quality of life of pregnant women. The aim of this study was to investigate the correlation between hemoglobin levels and the quality of life of pregnant women at Jetis 1 Primary Health Care in Bantul, Yogyakarta. This was an observational study with a cross-sectional approach and it was conducted from September to November 2019. The patients’ quality of life was measured by the Indonesian version of the SF-36 questionnaire. The hemoglobin level was mesured by a hemoglobin test. This study used univariate (descriptive) and bivariate data analysis using the Chi-square test. The results showed that there were 12 pregnant women (23.5%) who experienced mild anemia and 13 pregnant women with moderate anemia (25.5%). There was a significant corelation between hemoglobin levels and the quality of life of pregnant women (p < 0.05), especially in the domains of physical health (p = 0.034) and emotional...
Jurnal Insan Farmasi Indonesia
Individuals who survive a first ischemic stroke are at high risk for recurrent stroke. This study... more Individuals who survive a first ischemic stroke are at high risk for recurrent stroke. This study aims to analyze the relationship between antihypertensives on the incidence of ischemic stroke recurrence in ischemic stroke patients. Type of research is analytic observational with a retrospective cohort approach. The research sample was taken using purposive sampling technique. The research sample was patients who had an ischemic stroke at PKU Muhammadiyah Hospital Yogyakarta in 2018. There were 201 samples that met the inclusion criteria. Consisting of 135 treatment groups and 66 patients as the control group. In the treatment group, 110 patients did not have recurrent strokes and 25 patients had recurrent strokes. In the control group there were 58 patients who did not have recurrent strokes and 8 patients had recurrent strokes. Statistical analysis showed an RR value of 0.927 (95% CI: 0.822-1.046) and p-value of 0.344. The conclusion from the results of this study is that there is...
Prosiding Seminar Nasional Hasil Pengabdian Kepada Masyarakat Universitas Ahmad Dahlan, Oct 23, 2021
Medical Sains : Jurnal Ilmiah Kefarmasian
Proses pembedahan adalah proses pembukaan bagian tubuh yang akan ditangani dan diakhiri dengan pe... more Proses pembedahan adalah proses pembukaan bagian tubuh yang akan ditangani dan diakhiri dengan penutupan dan penjahitan luka. Kondisi ini memungkinkan terjadinya infeksi yang dapat dicegah dengan pemberian antibiotik. Penelitian ini bertujuan untuk mengetahui nilai DDD penggunaan antibiotik pada pasien rawat inap bedah umum di Rumah Sakit Umum Daerah (RSUD) Cilacap. Evaluasi penggunaan obat dengan DDD bertujuan untuk melihat gambaran dosis pemeliharaan rata-rata per hari suatu obat yang digunakan sebagai indikasi utama pada orang dewasa. Penelitian ini merupakan penelitian deskriptif yang akan dianalisis dengan DDD (Defined Daily Dose). Metode penelitian ini adalah retrospektif dengan menggunakan purposive sampling. Sampel penelitian sebanyak 162 rekam medis pasien dengan kriteria inklusi, pasien dewasa berusia 18-60 tahun yang mendapat terapi antibiotik serta data medis dan konsumsi obat lengkap pasien periode Januari–Juni 2019. Data yang diperoleh dianalisis pola penggunaan antib...
JURNAL ILMU KEFARMASIAN INDONESIA
Based on data from WHO (World Health Organization), it is estimated that 41.8% of anemia occurs i... more Based on data from WHO (World Health Organization), it is estimated that 41.8% of anemia occurs in pregnant women, with the highest prevalence rate of 61.3% in Africa and 52.5% in Asia. Pharmacist interventions have shown a positive effect in improving therapeutic adherence to hypertensive patients, as well as diabetes mellitus who routinely taking the drugs. The aim of the study was to know effect of giving patient information leaflet (PIL) along with motivational SMS on knowledge, perception, and compliance of pregnant patients in primary care. This study used a quasi-experimental method with pre-post design for two groups, the control group who received the Patient Information leaflet (PIL) and the intervention group who received the Patient Information leaflet (PIL) and motivational SMS from the researcher. Statistical analysis using SPSS with paired t test was used to determine differences in knowledge, perceptions and patient compliance before and after the intervention. Respo...
Jurnal Farmasi Udayana, 2021
Diabetes mellitus merupakan penyakit kronis yang membuat kadar gula darah meningkat. Bertambahnya... more Diabetes mellitus merupakan penyakit kronis yang membuat kadar gula darah meningkat. Bertambahnya usia mempengaruhi kinerja fungsi organ tubuh terhadap insulin mengarah terjadinya fluktuasi gula darah. Turunnya kinerja fungsi tubuh berpengaruh dalam keseimbangan fungsi tubuh yang lain sehingga dapat menyebabkan komplikasi. Tujuan penelitian yaitu mengetahui dan mengevaluasi kadar gula darah berdasarkan usia dan komplikasi penyakit. Rancangan penelitian yang dilakukan adalah penelitian observasional analitik. Pengambilan data dilakukan secara retrospektif dari bulan September - November 2019. Analisis univariat digunakan untuk melihat analisis karakteristik dasar variabel penelitian. Analisis bivariat digunakan untuk mengetahui perbedaan gula darah pasien berdasarkan usia dan komplikasi penyakit. Uji statistik yangdigunakan adalah uji Kruskal Wallis. Hasil penelitian menunjukkan kadar gula darah berdasarkan usia yang diperoleh adalah 0,289; 0,242; 0,150; 0,658; 0,557; 0,711(p > 0...
Advances in Health Sciences Research, 2021
Acute coronary syndromes ( ACS ) caused by an imbalance between oxygen supply and oxygen demand b... more Acute coronary syndromes ( ACS ) caused by an imbalance between oxygen supply and oxygen demand by the myocardium. Anticoagulants therapy is recommended and is the mainstay of therapy in patients with acute cardiovascular disease . This research aims to compare the effectiveness and costs in patients using enoxaparin and fondaparinux in patients with acute coronary syndromes . This study is a non - experimental cohort using retrospective medical record data RS.Bethesda Yogyakarta . The subjects of the study in which patients with acute coronary syndrome who received therapy enoxaparin and fondaparinux from January 2012 until December 2013.The effectiveness of therapy visits by the absence of myocardial infarction , ischemic repetitive , and death . Drug safety seen by the absence of major and minor bleeding . Cost analysis is done by calculating the cost of total therapy for patients hospitalized for . The number of patients who did not undergo myocardial infarction in group enoxaparin 17 patients ( 39.5 % ) , and 22 patients ( 78.6 % ) in group fondaparinux ( p = 0.006 , OR = 0.221 , 95 % CI = 0.073 to 0.667 ) . The difference in the number of patients who did not experience recurrent ischemic ie 34 patients in group enoxaparin , and 25 patients in the fondaparinux group ( p = 0.980 ; OR = 1.020 ; 95 % CI = 0.209 to 4.969 ) , and the number of patients who did not experience death is 37 ( 97.4 % ) , 28 ( 100 % ) ( p = 0.387 ; OR = 0.569 ; 95 % CI = 0.461 to 0.703 ) . occurrence minor bleeding in the enoxaparin and fondaparinux group of 35 ( 92.1 % ) , and 28 ( 100 % ) ( p = 0.128 ; OR = 0.556 ; 95 % CI 0.445 to 0.693 ) . effectiveness based on clinical outcomes absence of infarction was no significant difference , whereas the absence of ischemic and death is no different . security fondaparinux better than enoxaparin average total cost of the enoxaparin and fondaparinux group Rp 7073735.5 ± 4.051 million ) and Rp5,531,455.33 ± 1.915 million ) ( p = 0.161 ) . The total cost of therapy in fondaparinux more low compared to enoxaparin . The conclusion of this study is the effectiveness of enoxaparin and fondaparinux Similarly, the risk of bleeding in the lower fondaparinux , and costs fondaparinux therapy at a lower total.
Medical Sains : Jurnal Ilmiah Kefarmasian, 2022
Instrumen pengukuran kualitas hidup pada pasien kanker telah tervalidasi dan sudah diterjemahkan ... more Instrumen pengukuran kualitas hidup pada pasien kanker telah tervalidasi dan sudah diterjemahkan di banyak negara yaitu salah satunya adalah instrument EORTC QLQ C-30. Hal ini menyebabkan instrument ini telah digunakan pada banyak penelitian di berbagai negara di dunia. Tujuan penelitian ini adalah untuk memberikan gambaran bidang penelitian kualitas hidup menggunakan analisis bibliometrik berdasarkan literature dari tahun 1993 sampai dengan 2021 dan untuk melakukan analisis pola ilmiah penelitian kualitas hidup terutama pada pasien kanker payudara. Metode penelitian ini menggunakan PubMed sebagai database jurnal penelitian yang digunakan dengan strategi pencarian yaitu: ((Kualitas hidup) AND (kanker payudara)) AND (EORTC QLQ), termasuk juga menggunakan MesH terms. Kriteria inklusi pada penelitian ini adalah seluruh penelitian yang menggunakan kuesioner EORTC QLQ sebagai kuesioner kualitas hidup dan semua jenis penelitian, sedangkan artikel review, sistematik review dan meta analisa...
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice), 2021
Health clinicians often show different variations in the choice of therapy they prescribe for pat... more Health clinicians often show different variations in the choice of therapy they prescribe for patients depending on their expertise, knowledge, and even their art. This is likely to affect several things, including the cost that patients have to pay. Such a difference in costs is avoidable by applying scientific evidence-based medical service standards and having measurable outcomes known as Clinical Pathways. A clinical pathway serves as a tool to measure the quality of health services based on the standardization of the treatment process. This research was designed to determine the cost analysis of treatments received by patients with acute coronary syndrome (ACS) according to the clinical pathway. This non-experimental research employed a retrospective cohort study design. The data were gathered from the medical records of ACS patients who were treated at the ICCU of PKU Muhammadiyah Hospital in Yogyakarta, and the costs incurred were compared between treatments that matched and ...
JPSCR: Journal of Pharmaceutical Science and Clinical Research, 2022
Biaya perawatan pasien kanker nasofaring masih tinggi di Indonesia, penilaian kualitas hidup dan ... more Biaya perawatan pasien kanker nasofaring masih tinggi di Indonesia, penilaian kualitas hidup dan evaluasi ekonomi pasien kanker sangatlah penting, karena penyakit dan pengobatannya mempengaruhi kesejahteraan psikologis, sosial dan ekonomi, serta integritas biologis individu. Penelitian ini bertujuan untuk mengetahui kualitas hidup pasien kanker nasofaring yang menjalani kemoterapi di RSUP Dr. Kariadi Semarang. Penilaian kualitas hidup dilakukan menggunakan instrumen EORTC QLQ-C30. Penelitian ini merupakan penelitian observasional dengan desain cross sectional. Sampel penelitian ini merupakan pasien kanker nasofaring di RSUP dr. Kariadi, Semarang, Jawa Tengah, tepatnya di unit rawat jalan poliklinik onkologi dan rawat inap selama bulan Mei – Juli 2020 yang memenuhi kriteria inklusi dan eksklusi. Data yang telah didapatkan melalui pengisian kuesioner ditransformasikan menjadi skor dengan rentang 0-100 menggunakan rumus transformasi linier kemudian hasil kualitas hidup dideskripsikan d...
Jurnal Sains dan Kesehatan, 2021
Kanker payudara merupakan kanker yang paling umum dijumpai pada wanita dan merupaka kanker yang d... more Kanker payudara merupakan kanker yang paling umum dijumpai pada wanita dan merupaka kanker yang dominan di Indonesia. Pengobatan kanker seperti kemoterapi dapat berdampak pada kualitas hidup pasien baik fisik, psikologis, maupun sosial. Tujuan dari penelitian ini adalah untuk untuk mengetahui hubungan karakteristik terhadap kualitas hidup pasien kanker payudara. Penelitian ini merupakan penelitian dekstriptif dengan desain cross sectional study. Kualitas hidup pasien diukur menggunaan kuisioner EORTC QLQ-C30. Sampel penelitian ini adalah pasien kanker payudara di RSUP Dr Kariadi Semarang yang telah memenuhi kriteria inklusi. Data yang diperoleh dianalisis dengan uji statistik Mann-Whitney dan Kruskal Wallis. Dari hasil analisis karakteristik usia, pendidikan, pendapatan, status pernikahan, stadium kanker dan jenis kemoterapi memiliki hubungan terhadap status kesehatan global, skala fungsional dan skala gejala. Sedangkan pada karakteristik status pekerjaan tidak terdapat hubungan yan...
Advances in Health Sciences Research, 2021
Anemia in pregnancy is one of the causes of death in pregnant women. Approximately, 41.8% of anem... more Anemia in pregnancy is one of the causes of death in pregnant women. Approximately, 41.8% of anemia cases occurred in pregnant women, with the highest prevalence rate of 61.3% in the African region and 52.5% in the Asian region. WHO states that 58% of anemia in pregnancy is caused by iron deficiency. The Public Health Office has promoted a program to treat anemia in pregnant women by providing iron supplements containing iron and folic acid. However, non-compliance in the consumption of these supplements is still a problem among pregnant women patients. This study aimed to determine the correlation between level of knowledge, perception, and compliance of pregnant women in consuming ferrous fumarate tablets in the Public Health Center (Puskesmas) Jetis 1, Bantul, Yogyakarta. This study used an analytic observational method with a cross sectional approach. The sample was selected using the consecutive sampling technique. Sixty respondents were recruited based on inclusion criteria. The inclusion criteria were pregnant women who had their pregnancy checked at Puskesmas Jetis 1 Bantul Yogyakarta, aged between 16-45 years, received ferrous fumarate supplements, were not deaf and not illiterate, and were cooperative. The data obtained from the questionnaire were analyzed univariately using the frequency distribution (proportion) test and bivariately using the Chi-Square test. The results of the analysis showed that 43 (71.7%) respondents had a good level of knowledge, 29 (48.3%) respondents had a positive perception, and 39 (65.0%) respondents complied with the ferrous fumarate consumption. The correlation between knowledge level and compliance with ferrous fumarate consumption showed p = 0.002; OR = 6.05; CI = 95% (1.79-20.51). The correlation between perception and compliance with ferrous fumarate consumption showed p = 0.935; OR = 1.05; CI = 95% (0.36-3.02). In conclusion, the results of this study indicated that there was a significant correlation between the respondents' level of knowledge and level of compliance with ferrous fumarate tablet consumption.
Journal Syifa Sciences and Clinical Research, Feb 13, 2022
Anemia kehamilan masih menjadi permasalahan kesehatan di Indonesia. Pemberian tablet zat besi (Fe... more Anemia kehamilan masih menjadi permasalahan kesehatan di Indonesia. Pemberian tablet zat besi (Fe) merupakan upaya pencegahan yang dilakukan pemerintah di pelayanan kesehatan primer. Namun demikian rerata cakupan tablet Fe nasional masih belum maksimal (85,1%). Penelitian terkait kepatuhan konsumsi tablet zat besi masih cukup terbatas, oleh karena itu penelitian ini bertujuan untuk mengetahui hubungan tingkat kepatuhan konsumsi tablet zat besi dengan kejadian anemia wanita hamil di pelayanan kesehatan primer.Penelitian menggunakan metode observasional analitik dengan pendekatan cross sectional, dilakukan pada periode Agustus-November 2019 di Puskesmas Jetis I Bantul Yogyakarta. Sejumlah 39 responden yang memenuhi kriteria inklusi dan menyetujui informed consent direkrut dalam penelitian ini. Data tingkat kepatuhan diambil melalui wawancara responden menggunakan instrumen kuisioner dan pengecekan pill count minimal pada hari ke-7 setelah konsumsi tablet zat besi sedangkan kadar Hb diambil dari data rekam medik dan pemeriksaan responden. Analisis statistik dilakukan menggunakan uji chi square. Hasil penelitian menunjukkan 61,5% wanita hamil patuh dalam mengonsumsi tablet zat besi, sedangkan pengukuran pill count menunjukkan 59,0% ibu hamil patuh. Terdapat hubungan signifikan antara konsumsi tablet zat besi dengan kejadian anemia kehamilan, baik kepatuhan pada pengukuran kuisioner p=0,000; OR=0,050; (CI:0,010-0,263), ataupun pengukuran pill count p=0,003; OR=0,126 (CI:0,030-0,538). Sejumlah 15,4% wanita hamil mengalami anemia pada usia kehamilan trimester 2, dan 25,6% pada trimester 3. Berdasarkan penelitian ini disimpulkan bahwa terdapat hubungan antara tingkat kepatuhan konsumsi tablet zat besi terhadap kejadian anemia wanita hamil.
Journal of Advanced Pharmacy Education and Research
Asian Pacific Journal of Cancer Prevention
Objective: This study aims to develop a mapping algorithm for EORTC QLQ-C30 to EQ-5D-5L which can... more Objective: This study aims to develop a mapping algorithm for EORTC QLQ-C30 to EQ-5D-5L which can produce utility values in patients with cancer. Methods: We used a cross sectional study design with 300 cancer patients. The research instruments used were EORTC QLQ-C30 and EQ-5D-5L. Data were collected by interviewing cancer patients who were hospitalized in the Kasuari Installation of Dr Kariadi Hospital Semarang, Indonesia. The Ordinary Least Squares (OLS) regression method was used to predict the utility value of EQ-5D-5L. This study uses two models to predict utility values, namely model 1 with all domains, and model 2 with domains that affect the EQ-5D-5L. The predictive power of regression on the model is evaluated by calculating the mean absolute error (MAE) and root mean square error (RMSE) values. Result: The highest score in the functional domain is the 'emotional function' domain (mean: 85.89; SD: 16.04) and the highest symptom domain is 'weakness' (mean: 36.21; SD:21.69). The predicted utility values of models 1 and 2 are 0.683. The mean absolute error (MAE) and root mean square error (RMSE) values of model 1 are 0.128 and 0.173, while in model 2 the MAE and RMSE values obtained are 0.125 and 0.168. Conclusion: The development of the mapping algorithm from the EORTC QLQ-C30 to EQ-5D-5L instrument shows a predictive value of utility in a sample of patients with cancer at Dr. Kariadi Hospital, Semarang, Indonesia. The utility prediction in both model is similar, however model 2 involves fewer domains and symptoms.
International Journal of Clinical Practice
One of the important outcomes to define the success of cancer treatment is the health-related qua... more One of the important outcomes to define the success of cancer treatment is the health-related quality of life (HRQoL) that can be measured using generic and/or specific instruments. Our study aims to define the cancer patients’ HRQoL in some hospitals in Indonesia as measured by the European Organization for Research and Treatment for Cancer (EORTC QLQ-C30) and the EQ-5D-5L, to define the differences of cancer patients’ HRQoL referring to patients’ characteristics, and to explore determinants of cancer patients’ HRQoL. We recruited 451 cancer patients using a cross-sectional design in two referral hospitals in Central Java, Indonesia, using the purposive sampling technique. All subjects, recruited from July 2020 to October 2021, met the inclusion criteria, namely, adult patients diagnosed with cancers in all stages who willingly participated in the study. The Indonesian value set was used to obtain the EQ-5D-5L index score. We further analyzed the data based on cancer stages and com...
Jurnal Farmasi Udayana
Virus Corona yang ditemukan di Wuhan memberikan tantangan dikalangan petugas kesehatan seperti ap... more Virus Corona yang ditemukan di Wuhan memberikan tantangan dikalangan petugas kesehatan seperti apoteker yang bertanggung jawab memberikan edukasi kepada masyarakat khususnya terhadap COVID 19. Penelitian ini bertujuan untuk mengukur tingkat pengetahuan, persepsi dan sikap apoteker di apotek Kota Yogyakarta mengenai COVID-19. Desain penelitian adalah observasional analitik dengan populasi apoteker yang berpraktik di apotek Kota Yogyakarta dan sampel penelitian apoteker yang berpraktik di apotek minimal 6 bulan. Hasil penelitian menunjukkan apoteker di apotek kota Yogyakarta memiliki pengetahuan baik mengenai COVID-19 (60%) dan 40% apoteker memiliki pengetahuan yang cukup. Apoteker memiliki persepsi positif sebanyak 66% dan persepsi negatif sebanyak 34% Sikap apoteker menunjukkan 68% positif dan dan 32% negatif. Hubungan tingkat pendidikan dengan pengetahuan, persepsi dan sikap apoteker diperoleh nilai p berturut-turut 0.241, 0.806 dan 0.094, sedangkan hubungan lama pengalaman beker...
Journal Syifa Sciences and Clinical Research, Feb 12, 2022
Swamedikasi merupakan salah satu upaya yang paling banyak dilakukan oleh seseorang dalam mengatas... more Swamedikasi merupakan salah satu upaya yang paling banyak dilakukan oleh seseorang dalam mengatasi gejala sakit ringan yang sedang dideritanya sebelum melakukan konsultasi kepada tenaga kesehatan. Hasil Survei Sosial Ekonomi Nasional (Susenas) tahun 2014 menunjukkan bahwa presentase penduduk yang memilih swamedikasi atau pengobatan diri sendiri akibat keluhan kesehatan yang dialami sebesar 61,05%. Banyak faktor yang mempengaruhi masyarakat untuk melakukan pengobatan, salah satunya adalah iklan. Tujuan penelitian untuk mengetahui hubungan antara pengaruh iklan obat terhadap keputusan pemilihan obat serta ketepatan tindakan swamedikasi pada masyarakat di Kecamatan Umbulharjo Kota Yogyakarta. Desain penelitian ini adalah observasional analitik dengan pengambilan data secara cross-sectional. Teknik pengambilan sampel menggunakan metode insidental sampling dan data dikumpulkan melalui pengisian kuesioner yang telah divalidasi. Analisis data dilakukan dengan uji univariate dan bivariate dengan menggunakan SPSS 20.0. Hasil penelitian menunjukkan bahwa hasil uji signifikansi antara pengaruh iklan obat di televise terhadap ketepatan tindakan swamedikasi adalah 0,864. Kesimpulan pada penelitian ini bahwa iklan tidak memiliki pengaruh terhadap ketepatan tindakan swamedikasi masyarakat (p> 0,05).
KnE Medicine
48.9% of pregnant women in Indonesia in 2018 had anemia. This can affect the health and quality o... more 48.9% of pregnant women in Indonesia in 2018 had anemia. This can affect the health and quality of life of pregnant women. The aim of this study was to investigate the correlation between hemoglobin levels and the quality of life of pregnant women at Jetis 1 Primary Health Care in Bantul, Yogyakarta. This was an observational study with a cross-sectional approach and it was conducted from September to November 2019. The patients’ quality of life was measured by the Indonesian version of the SF-36 questionnaire. The hemoglobin level was mesured by a hemoglobin test. This study used univariate (descriptive) and bivariate data analysis using the Chi-square test. The results showed that there were 12 pregnant women (23.5%) who experienced mild anemia and 13 pregnant women with moderate anemia (25.5%). There was a significant corelation between hemoglobin levels and the quality of life of pregnant women (p < 0.05), especially in the domains of physical health (p = 0.034) and emotional...
Jurnal Insan Farmasi Indonesia
Individuals who survive a first ischemic stroke are at high risk for recurrent stroke. This study... more Individuals who survive a first ischemic stroke are at high risk for recurrent stroke. This study aims to analyze the relationship between antihypertensives on the incidence of ischemic stroke recurrence in ischemic stroke patients. Type of research is analytic observational with a retrospective cohort approach. The research sample was taken using purposive sampling technique. The research sample was patients who had an ischemic stroke at PKU Muhammadiyah Hospital Yogyakarta in 2018. There were 201 samples that met the inclusion criteria. Consisting of 135 treatment groups and 66 patients as the control group. In the treatment group, 110 patients did not have recurrent strokes and 25 patients had recurrent strokes. In the control group there were 58 patients who did not have recurrent strokes and 8 patients had recurrent strokes. Statistical analysis showed an RR value of 0.927 (95% CI: 0.822-1.046) and p-value of 0.344. The conclusion from the results of this study is that there is...
Prosiding Seminar Nasional Hasil Pengabdian Kepada Masyarakat Universitas Ahmad Dahlan, Oct 23, 2021
Medical Sains : Jurnal Ilmiah Kefarmasian
Proses pembedahan adalah proses pembukaan bagian tubuh yang akan ditangani dan diakhiri dengan pe... more Proses pembedahan adalah proses pembukaan bagian tubuh yang akan ditangani dan diakhiri dengan penutupan dan penjahitan luka. Kondisi ini memungkinkan terjadinya infeksi yang dapat dicegah dengan pemberian antibiotik. Penelitian ini bertujuan untuk mengetahui nilai DDD penggunaan antibiotik pada pasien rawat inap bedah umum di Rumah Sakit Umum Daerah (RSUD) Cilacap. Evaluasi penggunaan obat dengan DDD bertujuan untuk melihat gambaran dosis pemeliharaan rata-rata per hari suatu obat yang digunakan sebagai indikasi utama pada orang dewasa. Penelitian ini merupakan penelitian deskriptif yang akan dianalisis dengan DDD (Defined Daily Dose). Metode penelitian ini adalah retrospektif dengan menggunakan purposive sampling. Sampel penelitian sebanyak 162 rekam medis pasien dengan kriteria inklusi, pasien dewasa berusia 18-60 tahun yang mendapat terapi antibiotik serta data medis dan konsumsi obat lengkap pasien periode Januari–Juni 2019. Data yang diperoleh dianalisis pola penggunaan antib...
JURNAL ILMU KEFARMASIAN INDONESIA
Based on data from WHO (World Health Organization), it is estimated that 41.8% of anemia occurs i... more Based on data from WHO (World Health Organization), it is estimated that 41.8% of anemia occurs in pregnant women, with the highest prevalence rate of 61.3% in Africa and 52.5% in Asia. Pharmacist interventions have shown a positive effect in improving therapeutic adherence to hypertensive patients, as well as diabetes mellitus who routinely taking the drugs. The aim of the study was to know effect of giving patient information leaflet (PIL) along with motivational SMS on knowledge, perception, and compliance of pregnant patients in primary care. This study used a quasi-experimental method with pre-post design for two groups, the control group who received the Patient Information leaflet (PIL) and the intervention group who received the Patient Information leaflet (PIL) and motivational SMS from the researcher. Statistical analysis using SPSS with paired t test was used to determine differences in knowledge, perceptions and patient compliance before and after the intervention. Respo...
Jurnal Farmasi Udayana, 2021
Diabetes mellitus merupakan penyakit kronis yang membuat kadar gula darah meningkat. Bertambahnya... more Diabetes mellitus merupakan penyakit kronis yang membuat kadar gula darah meningkat. Bertambahnya usia mempengaruhi kinerja fungsi organ tubuh terhadap insulin mengarah terjadinya fluktuasi gula darah. Turunnya kinerja fungsi tubuh berpengaruh dalam keseimbangan fungsi tubuh yang lain sehingga dapat menyebabkan komplikasi. Tujuan penelitian yaitu mengetahui dan mengevaluasi kadar gula darah berdasarkan usia dan komplikasi penyakit. Rancangan penelitian yang dilakukan adalah penelitian observasional analitik. Pengambilan data dilakukan secara retrospektif dari bulan September - November 2019. Analisis univariat digunakan untuk melihat analisis karakteristik dasar variabel penelitian. Analisis bivariat digunakan untuk mengetahui perbedaan gula darah pasien berdasarkan usia dan komplikasi penyakit. Uji statistik yangdigunakan adalah uji Kruskal Wallis. Hasil penelitian menunjukkan kadar gula darah berdasarkan usia yang diperoleh adalah 0,289; 0,242; 0,150; 0,658; 0,557; 0,711(p > 0...
Advances in Health Sciences Research, 2021
Acute coronary syndromes ( ACS ) caused by an imbalance between oxygen supply and oxygen demand b... more Acute coronary syndromes ( ACS ) caused by an imbalance between oxygen supply and oxygen demand by the myocardium. Anticoagulants therapy is recommended and is the mainstay of therapy in patients with acute cardiovascular disease . This research aims to compare the effectiveness and costs in patients using enoxaparin and fondaparinux in patients with acute coronary syndromes . This study is a non - experimental cohort using retrospective medical record data RS.Bethesda Yogyakarta . The subjects of the study in which patients with acute coronary syndrome who received therapy enoxaparin and fondaparinux from January 2012 until December 2013.The effectiveness of therapy visits by the absence of myocardial infarction , ischemic repetitive , and death . Drug safety seen by the absence of major and minor bleeding . Cost analysis is done by calculating the cost of total therapy for patients hospitalized for . The number of patients who did not undergo myocardial infarction in group enoxaparin 17 patients ( 39.5 % ) , and 22 patients ( 78.6 % ) in group fondaparinux ( p = 0.006 , OR = 0.221 , 95 % CI = 0.073 to 0.667 ) . The difference in the number of patients who did not experience recurrent ischemic ie 34 patients in group enoxaparin , and 25 patients in the fondaparinux group ( p = 0.980 ; OR = 1.020 ; 95 % CI = 0.209 to 4.969 ) , and the number of patients who did not experience death is 37 ( 97.4 % ) , 28 ( 100 % ) ( p = 0.387 ; OR = 0.569 ; 95 % CI = 0.461 to 0.703 ) . occurrence minor bleeding in the enoxaparin and fondaparinux group of 35 ( 92.1 % ) , and 28 ( 100 % ) ( p = 0.128 ; OR = 0.556 ; 95 % CI 0.445 to 0.693 ) . effectiveness based on clinical outcomes absence of infarction was no significant difference , whereas the absence of ischemic and death is no different . security fondaparinux better than enoxaparin average total cost of the enoxaparin and fondaparinux group Rp 7073735.5 ± 4.051 million ) and Rp5,531,455.33 ± 1.915 million ) ( p = 0.161 ) . The total cost of therapy in fondaparinux more low compared to enoxaparin . The conclusion of this study is the effectiveness of enoxaparin and fondaparinux Similarly, the risk of bleeding in the lower fondaparinux , and costs fondaparinux therapy at a lower total.
Medical Sains : Jurnal Ilmiah Kefarmasian, 2022
Instrumen pengukuran kualitas hidup pada pasien kanker telah tervalidasi dan sudah diterjemahkan ... more Instrumen pengukuran kualitas hidup pada pasien kanker telah tervalidasi dan sudah diterjemahkan di banyak negara yaitu salah satunya adalah instrument EORTC QLQ C-30. Hal ini menyebabkan instrument ini telah digunakan pada banyak penelitian di berbagai negara di dunia. Tujuan penelitian ini adalah untuk memberikan gambaran bidang penelitian kualitas hidup menggunakan analisis bibliometrik berdasarkan literature dari tahun 1993 sampai dengan 2021 dan untuk melakukan analisis pola ilmiah penelitian kualitas hidup terutama pada pasien kanker payudara. Metode penelitian ini menggunakan PubMed sebagai database jurnal penelitian yang digunakan dengan strategi pencarian yaitu: ((Kualitas hidup) AND (kanker payudara)) AND (EORTC QLQ), termasuk juga menggunakan MesH terms. Kriteria inklusi pada penelitian ini adalah seluruh penelitian yang menggunakan kuesioner EORTC QLQ sebagai kuesioner kualitas hidup dan semua jenis penelitian, sedangkan artikel review, sistematik review dan meta analisa...
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice), 2021
Health clinicians often show different variations in the choice of therapy they prescribe for pat... more Health clinicians often show different variations in the choice of therapy they prescribe for patients depending on their expertise, knowledge, and even their art. This is likely to affect several things, including the cost that patients have to pay. Such a difference in costs is avoidable by applying scientific evidence-based medical service standards and having measurable outcomes known as Clinical Pathways. A clinical pathway serves as a tool to measure the quality of health services based on the standardization of the treatment process. This research was designed to determine the cost analysis of treatments received by patients with acute coronary syndrome (ACS) according to the clinical pathway. This non-experimental research employed a retrospective cohort study design. The data were gathered from the medical records of ACS patients who were treated at the ICCU of PKU Muhammadiyah Hospital in Yogyakarta, and the costs incurred were compared between treatments that matched and ...
JPSCR: Journal of Pharmaceutical Science and Clinical Research, 2022
Biaya perawatan pasien kanker nasofaring masih tinggi di Indonesia, penilaian kualitas hidup dan ... more Biaya perawatan pasien kanker nasofaring masih tinggi di Indonesia, penilaian kualitas hidup dan evaluasi ekonomi pasien kanker sangatlah penting, karena penyakit dan pengobatannya mempengaruhi kesejahteraan psikologis, sosial dan ekonomi, serta integritas biologis individu. Penelitian ini bertujuan untuk mengetahui kualitas hidup pasien kanker nasofaring yang menjalani kemoterapi di RSUP Dr. Kariadi Semarang. Penilaian kualitas hidup dilakukan menggunakan instrumen EORTC QLQ-C30. Penelitian ini merupakan penelitian observasional dengan desain cross sectional. Sampel penelitian ini merupakan pasien kanker nasofaring di RSUP dr. Kariadi, Semarang, Jawa Tengah, tepatnya di unit rawat jalan poliklinik onkologi dan rawat inap selama bulan Mei – Juli 2020 yang memenuhi kriteria inklusi dan eksklusi. Data yang telah didapatkan melalui pengisian kuesioner ditransformasikan menjadi skor dengan rentang 0-100 menggunakan rumus transformasi linier kemudian hasil kualitas hidup dideskripsikan d...
Jurnal Sains dan Kesehatan, 2021
Kanker payudara merupakan kanker yang paling umum dijumpai pada wanita dan merupaka kanker yang d... more Kanker payudara merupakan kanker yang paling umum dijumpai pada wanita dan merupaka kanker yang dominan di Indonesia. Pengobatan kanker seperti kemoterapi dapat berdampak pada kualitas hidup pasien baik fisik, psikologis, maupun sosial. Tujuan dari penelitian ini adalah untuk untuk mengetahui hubungan karakteristik terhadap kualitas hidup pasien kanker payudara. Penelitian ini merupakan penelitian dekstriptif dengan desain cross sectional study. Kualitas hidup pasien diukur menggunaan kuisioner EORTC QLQ-C30. Sampel penelitian ini adalah pasien kanker payudara di RSUP Dr Kariadi Semarang yang telah memenuhi kriteria inklusi. Data yang diperoleh dianalisis dengan uji statistik Mann-Whitney dan Kruskal Wallis. Dari hasil analisis karakteristik usia, pendidikan, pendapatan, status pernikahan, stadium kanker dan jenis kemoterapi memiliki hubungan terhadap status kesehatan global, skala fungsional dan skala gejala. Sedangkan pada karakteristik status pekerjaan tidak terdapat hubungan yan...
Advances in Health Sciences Research, 2021
Anemia in pregnancy is one of the causes of death in pregnant women. Approximately, 41.8% of anem... more Anemia in pregnancy is one of the causes of death in pregnant women. Approximately, 41.8% of anemia cases occurred in pregnant women, with the highest prevalence rate of 61.3% in the African region and 52.5% in the Asian region. WHO states that 58% of anemia in pregnancy is caused by iron deficiency. The Public Health Office has promoted a program to treat anemia in pregnant women by providing iron supplements containing iron and folic acid. However, non-compliance in the consumption of these supplements is still a problem among pregnant women patients. This study aimed to determine the correlation between level of knowledge, perception, and compliance of pregnant women in consuming ferrous fumarate tablets in the Public Health Center (Puskesmas) Jetis 1, Bantul, Yogyakarta. This study used an analytic observational method with a cross sectional approach. The sample was selected using the consecutive sampling technique. Sixty respondents were recruited based on inclusion criteria. The inclusion criteria were pregnant women who had their pregnancy checked at Puskesmas Jetis 1 Bantul Yogyakarta, aged between 16-45 years, received ferrous fumarate supplements, were not deaf and not illiterate, and were cooperative. The data obtained from the questionnaire were analyzed univariately using the frequency distribution (proportion) test and bivariately using the Chi-Square test. The results of the analysis showed that 43 (71.7%) respondents had a good level of knowledge, 29 (48.3%) respondents had a positive perception, and 39 (65.0%) respondents complied with the ferrous fumarate consumption. The correlation between knowledge level and compliance with ferrous fumarate consumption showed p = 0.002; OR = 6.05; CI = 95% (1.79-20.51). The correlation between perception and compliance with ferrous fumarate consumption showed p = 0.935; OR = 1.05; CI = 95% (0.36-3.02). In conclusion, the results of this study indicated that there was a significant correlation between the respondents' level of knowledge and level of compliance with ferrous fumarate tablet consumption.
Journal Syifa Sciences and Clinical Research, Feb 13, 2022
Anemia kehamilan masih menjadi permasalahan kesehatan di Indonesia. Pemberian tablet zat besi (Fe... more Anemia kehamilan masih menjadi permasalahan kesehatan di Indonesia. Pemberian tablet zat besi (Fe) merupakan upaya pencegahan yang dilakukan pemerintah di pelayanan kesehatan primer. Namun demikian rerata cakupan tablet Fe nasional masih belum maksimal (85,1%). Penelitian terkait kepatuhan konsumsi tablet zat besi masih cukup terbatas, oleh karena itu penelitian ini bertujuan untuk mengetahui hubungan tingkat kepatuhan konsumsi tablet zat besi dengan kejadian anemia wanita hamil di pelayanan kesehatan primer.Penelitian menggunakan metode observasional analitik dengan pendekatan cross sectional, dilakukan pada periode Agustus-November 2019 di Puskesmas Jetis I Bantul Yogyakarta. Sejumlah 39 responden yang memenuhi kriteria inklusi dan menyetujui informed consent direkrut dalam penelitian ini. Data tingkat kepatuhan diambil melalui wawancara responden menggunakan instrumen kuisioner dan pengecekan pill count minimal pada hari ke-7 setelah konsumsi tablet zat besi sedangkan kadar Hb diambil dari data rekam medik dan pemeriksaan responden. Analisis statistik dilakukan menggunakan uji chi square. Hasil penelitian menunjukkan 61,5% wanita hamil patuh dalam mengonsumsi tablet zat besi, sedangkan pengukuran pill count menunjukkan 59,0% ibu hamil patuh. Terdapat hubungan signifikan antara konsumsi tablet zat besi dengan kejadian anemia kehamilan, baik kepatuhan pada pengukuran kuisioner p=0,000; OR=0,050; (CI:0,010-0,263), ataupun pengukuran pill count p=0,003; OR=0,126 (CI:0,030-0,538). Sejumlah 15,4% wanita hamil mengalami anemia pada usia kehamilan trimester 2, dan 25,6% pada trimester 3. Berdasarkan penelitian ini disimpulkan bahwa terdapat hubungan antara tingkat kepatuhan konsumsi tablet zat besi terhadap kejadian anemia wanita hamil.