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Papers by carlos hernan
The Journal of Infection in Developing Countries, 2010
Background: Multidrug-resistant strains of Acinetobacter baumannii have been reported increasingl... more Background: Multidrug-resistant strains of Acinetobacter baumannii have been reported increasingly around the world. The administration of an association of antibiotics has been proposed to create an active combination and to prevent the emergence of resistance. Methodology: The activity of colistin, rifampicin, gentamicin, imipenem and their associations was evaluated by means of killing curves in fourteen isolates belonging to three endemic PFGE types, in a university hospital of Buenos Aires city. The 14 isolates were selected on the basis of different mechanisms responsible for resistance to carbapenems and different susceptibility to colistin. Results: The mechanism responsible for the resistance to imipenem was the production of OXA-23 and OXA-58 carbapenemases. Heteroresistance to colistin was observed in six isolates. The associations colistin-rifampicin and colistin-imipenem were synergistic in heteroresistant isolates and prevented the development of colistin-resistant mutants. The association imipenem-gentamicin was bactericidal in gentamicin susceptible isolates, whereas the association imipenem-rifampicin was always indifferent. Conclusion: The antimicrobial activity and the presence of synergy are related to the antimicrobials' susceptibilities irrespective of the PFGE type or the OXA-carbapenemase produced.
Base de dados : LILACS. Pesquisa : 519259 [Identificador único]. Referências encontradas : 1 [ref... more Base de dados : LILACS. Pesquisa : 519259 [Identificador único]. Referências encontradas : 1 [refinar]. Mostrando: 1 .. 1 no formato [Detalhado]. página 1 de 1, 1 / 1, LILACS, seleciona. para imprimir. Fotocópia. Texto completo. experimental, Documentos relacionados. Id: 519259 ...
Archivos De Bronconeumologia, 2004
European Food Research and Technology, 2010
Several reports suggested the activation of caspases in postmortem muscle implicating the onset o... more Several reports suggested the activation of caspases in postmortem muscle implicating the onset of a caspase-dependent cell death process after animal bleeding. It has been further well established that apoptosis and necrosis are the two major cell death pathways. The questions addressed in the present work were as follows: (a) in postmortem muscle, do cells die as in vivo? and (b) if so, by which dying process this goal is achieved? Selected hallmarks of apoptosis (phosphatidylserine externalization (PS), cell shrinkage, actin degradation) were analyzed in postmortem rat muscles and compared to usual cell behavior in apoptotic and necrotic processes. Results presented clearly demonstrate a rapid PS externalization and cell shrinkage extending during the first 24 h postexsanguination together with a progressive degradation of cytoskeletal and thin filaments of actin. It was therefore concluded that, in postmortem muscle, cells commit suicide soon after animal bleeding through apoptosis.
Medicina Clinica, 2005
AUTORÍA JOSÉ LÓPEZ TORRES TEMÁTICA INTERDISCIPLINARIEDAD: FOMENTO DE LA LECTURA DESDE DISTNTAS ÁR... more AUTORÍA JOSÉ LÓPEZ TORRES TEMÁTICA INTERDISCIPLINARIEDAD: FOMENTO DE LA LECTURA DESDE DISTNTAS ÁREAS ETAPA EDUCACIÓN PRIMARIA
Tropical countries have a great comparative advantage due to the intensity and regular availabili... more Tropical countries have a great comparative advantage due to the intensity and regular availability of solar energy which may be exploited through plant photosynthesis. Sugarcane is a C4 plant which has a greater capacity to utilize high light intensities with reduced water requirement and hence produce as much as 3.8 times more biomass per hectare than cereals. Total biomass yields of 255-480 T/ha are reported.
AUTORÍA JOSÉ LÓPEZ TORRES TEMÁTICA INTERDISCIPLINARIEDAD: FOMENTO DE LA LECTURA DESDE DISTNTAS ÁR... more AUTORÍA JOSÉ LÓPEZ TORRES TEMÁTICA INTERDISCIPLINARIEDAD: FOMENTO DE LA LECTURA DESDE DISTNTAS ÁREAS ETAPA EDUCACIÓN PRIMARIA
The Journal of Infection in Developing Countries, 2010
Background: Multidrug-resistant strains of Acinetobacter baumannii have been reported increasingl... more Background: Multidrug-resistant strains of Acinetobacter baumannii have been reported increasingly around the world. The administration of an association of antibiotics has been proposed to create an active combination and to prevent the emergence of resistance. Methodology: The activity of colistin, rifampicin, gentamicin, imipenem and their associations was evaluated by means of killing curves in fourteen isolates belonging to three endemic PFGE types, in a university hospital of Buenos Aires city. The 14 isolates were selected on the basis of different mechanisms responsible for resistance to carbapenems and different susceptibility to colistin. Results: The mechanism responsible for the resistance to imipenem was the production of OXA-23 and OXA-58 carbapenemases. Heteroresistance to colistin was observed in six isolates. The associations colistin-rifampicin and colistin-imipenem were synergistic in heteroresistant isolates and prevented the development of colistin-resistant mutants. The association imipenem-gentamicin was bactericidal in gentamicin susceptible isolates, whereas the association imipenem-rifampicin was always indifferent. Conclusion: The antimicrobial activity and the presence of synergy are related to the antimicrobials' susceptibilities irrespective of the PFGE type or the OXA-carbapenemase produced.
Base de dados : LILACS. Pesquisa : 519259 [Identificador único]. Referências encontradas : 1 [ref... more Base de dados : LILACS. Pesquisa : 519259 [Identificador único]. Referências encontradas : 1 [refinar]. Mostrando: 1 .. 1 no formato [Detalhado]. página 1 de 1, 1 / 1, LILACS, seleciona. para imprimir. Fotocópia. Texto completo. experimental, Documentos relacionados. Id: 519259 ...
Archivos De Bronconeumologia, 2004
European Food Research and Technology, 2010
Several reports suggested the activation of caspases in postmortem muscle implicating the onset o... more Several reports suggested the activation of caspases in postmortem muscle implicating the onset of a caspase-dependent cell death process after animal bleeding. It has been further well established that apoptosis and necrosis are the two major cell death pathways. The questions addressed in the present work were as follows: (a) in postmortem muscle, do cells die as in vivo? and (b) if so, by which dying process this goal is achieved? Selected hallmarks of apoptosis (phosphatidylserine externalization (PS), cell shrinkage, actin degradation) were analyzed in postmortem rat muscles and compared to usual cell behavior in apoptotic and necrotic processes. Results presented clearly demonstrate a rapid PS externalization and cell shrinkage extending during the first 24 h postexsanguination together with a progressive degradation of cytoskeletal and thin filaments of actin. It was therefore concluded that, in postmortem muscle, cells commit suicide soon after animal bleeding through apoptosis.
Medicina Clinica, 2005
AUTORÍA JOSÉ LÓPEZ TORRES TEMÁTICA INTERDISCIPLINARIEDAD: FOMENTO DE LA LECTURA DESDE DISTNTAS ÁR... more AUTORÍA JOSÉ LÓPEZ TORRES TEMÁTICA INTERDISCIPLINARIEDAD: FOMENTO DE LA LECTURA DESDE DISTNTAS ÁREAS ETAPA EDUCACIÓN PRIMARIA
Tropical countries have a great comparative advantage due to the intensity and regular availabili... more Tropical countries have a great comparative advantage due to the intensity and regular availability of solar energy which may be exploited through plant photosynthesis. Sugarcane is a C4 plant which has a greater capacity to utilize high light intensities with reduced water requirement and hence produce as much as 3.8 times more biomass per hectare than cereals. Total biomass yields of 255-480 T/ha are reported.
AUTORÍA JOSÉ LÓPEZ TORRES TEMÁTICA INTERDISCIPLINARIEDAD: FOMENTO DE LA LECTURA DESDE DISTNTAS ÁR... more AUTORÍA JOSÉ LÓPEZ TORRES TEMÁTICA INTERDISCIPLINARIEDAD: FOMENTO DE LA LECTURA DESDE DISTNTAS ÁREAS ETAPA EDUCACIÓN PRIMARIA