Padhraig O'Loughlin | University College Dublin (original) (raw)

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Papers by Padhraig O'Loughlin

Research paper thumbnail of Fracture of the Medial Tubercle of the Posterior Process of the Talus: Magnetic Resonance Imaging Appearance with Clinical Follow-Up

Research paper thumbnail of Forefoot Injuries in Dancers

Clinics in Sports Medicine, 2008

Dancers, particularly ballet dancers, are artists and athletes. In dance, the choreographer acts ... more Dancers, particularly ballet dancers, are artists and athletes. In dance, the choreographer acts as a sculptor, using the dancer as a medium of expression. This often entails placing the dancer's body in positions that require extraordinary flexibility and movement, which requires controlled power and endurance. Ballet and other forms of dance can be highly demanding activities, with a lifetime injury incidence of up to 90%. Ballet is stressful particularly on the dancer's forefoot. The en pointe position of maximal plantarflexion through the forefoot, midfoot, and hindfoot requires tremendous flexibility and strength that only can be attained safely through many years of training. The forces experienced by the toes and metatarsals are extraordinary.

Research paper thumbnail of Comparing Stability of Different Single- and Double-Bundle Anterior Cruciate Ligament Reconstruction Techniques: A Cadaveric Study Using Navigation

Arthroscopy: The Journal of Arthroscopic & Related Surgery, 2010

Research paper thumbnail of Eleven-Year Results of the Anatomic Coated CFP Stem in Primary Total Hip Arthroplasty

The Journal of Arthroplasty, 2013

There is a paucity of intermediate term results relating to short stem prostheses. The current st... more There is a paucity of intermediate term results relating to short stem prostheses. The current study represents the longest follow-up results of the CFP prosthesis to the authors' best knowledge. Between January 1999 and December 2000, all total hip arthroplasty patients (n = 149), treated with this anatomic neck preserving stem in the authors' institution were enrolled in this study. After a mean follow-up time period of 11.2 years 117 patients were available for the follow-up examination. The mean HHS increased from 53 to 93. Overall, revision surgery was required in 11 patients (9.4%), with implant-associated complications noted in only five cases (4.3%). Aseptic loosening leading to implant removal was noted in four patients (3.4%). The current study's data suggest that the CFP implant, used in young patients undergoing primary total hip arthroplasty, is safe and provides excellent results after 11 years.

Research paper thumbnail of On the Horizon From the ORS

The Journal of the American Academy of Orthopaedic Surgeons

However, the synchrotron studies themselves also tell us what the capabilities of ABI really are ... more However, the synchrotron studies themselves also tell us what the capabilities of ABI really are and, therefore, what we should strive for from a system using a conventional x-ray source. For instance, we have found that ABI based on refraction information allows the visualization of soft tissues in intact specimens such as cadaveric knee (Figure 1), finger joints, and whole foot/ankle specimens while simultaneously producing high contrast in the calcified tissues. 5-7 The contrast for articular cartilage, including changes characteristic of ...

Research paper thumbnail of Paper # 129: Single Bundle vs. Double Bundle ACL Reconstruction in ACL/Meniscus Deficient Knees

Arthroscopy: The Journal of Arthroscopic & Related Surgery, 2011

Research paper thumbnail of Arthroscopic Mosaicplasty for Osteochondral Lesions of the Knee: Computer-Assisted Navigation Versus Freehand Technique

Arthroscopy: The Journal of Arthroscopic & Related Surgery, 2012

Research paper thumbnail of Effect of Tunnel Position and Graft Size in Single-Bundle Anterior Cruciate Ligament Reconstruction: An Evaluation of Time-Zero Knee Stability

Arthroscopy: The Journal of Arthroscopic & Related Surgery, 2011

Research paper thumbnail of Adjustable Cutting Blocks for Computer-Navigated Total Knee Arthroplasty

The Journal of Arthroplasty, 2010

Research paper thumbnail of Ankle Sprains and Instability in Dancers

Clinics in Sports Medicine, 2008

Research paper thumbnail of Arthroscopic-assisted Fluoroscopic Navigation for Retrograde Drilling of a Talar Osteochondral Lesion

Foot & Ankle International, 2009

Research paper thumbnail of Parathyroid Hormone (1-34) Augments Spinal Fusion, Fusion Mass Volume, and Fusion Mass Quality in a Rabbit Spinal Fusion Model

Research paper thumbnail of Clinical Tips: Retrograde Drilling Of Talar Osteochondral Defects

Foot & Ankle International, 2008

Contemporary methods of bone grafting osteochondral defects, in which the remaining overlying car... more Contemporary methods of bone grafting osteochondral defects, in which the remaining overlying cartilage is relatively well preserved, have inherent problems. The bony defects are often saucer-shaped and the cylindrical graft may not fill the void, leaving areas of cartilage with no underlying scaffold and obviating early weight bearing. Furthermore, to obtain a proper fill of the defect, tamping of the graft can cause excessive pressure and disruption of the overlying cartilage. In an effort to address these concerns, the authors propose the use of a biological viscous paste of calcium sulfate that hardens within 5 minutes when injected in a retrograde fashion into the talus. This confers a mechanical advantage of complete cystic fill of the cyst which allows early weight bearing. Calcium sulfate acts as an osteoconductive material that incorporates into host bone within 8 weeks. Donor site morbidity is eliminated using this system.

Research paper thumbnail of Pigmented Villonodular Synovitis about the Ankle: Two Case Reports

Foot & Ankle International, 2008

... 2008 May;29(5):527-33. Pigmented villonodular synovitis about the ankle: two case reports. He... more ... 2008 May;29(5):527-33. Pigmented villonodular synovitis about the ankle: two case reports. Heller SL, O'Loughlin PF, Di Carlo G, Mintz DN, Kennedy JG. Hospital for Special Surgery, New York, NY 10021, USA. PMID: 18510910 [PubMed - indexed for MEDLINE]. ...

Research paper thumbnail of Selection and Development of Preclinical Models in Fracture-Healing Research

The Journal of Bone and Joint Surgery (American), 2008

Animal fracture models have been extensively applied to preclinical research as a platform to ide... more Animal fracture models have been extensively applied to preclinical research as a platform to identify and characterize normal and abnormal physiological processes and to develop specific maneuvers that alter the biology and biomechanics being examined. The choice of animal model employed in a study bears a direct relationship to the specific intervention being analyzed. The animal models employed should be described clearly, control-group data should be established, and reproducibility should be defined from experiment to experiment and from institution to institution so that quantitative and qualitative outcomes can be reliably compared and contrasted to other related studies.

Research paper thumbnail of Navigated reconstruction of a tibial plateau compression fracture post-virtual reconstruction

Research paper thumbnail of Sequential versus automated cutting guides in computer-assisted total knee arthroplasty

Research paper thumbnail of Anteromedial versus central single-bundle graft position: which anatomic graft position to choose?

Knee Surgery, Sports Traumatology, Arthroscopy, 2012

To compare the time-zero stability of an anatomic anteromedial (AM) single-bundle ACL reconstruct... more To compare the time-zero stability of an anatomic anteromedial (AM) single-bundle ACL reconstruction to an anatomic central (CTR) single-bundle ACL reconstruction. Twelve (6 paired) hip to knee cadaveric specimens were studied. Using custom ACL computer navigation software, a Lachman test and a previously validated, navigated mechanized pivot shift test were performed on 4 separate experimental groups in each specimen: (1) intact ACL, (2) ACL deficient with total medial and lateral meniscectomy, (3) following anatomic AM single-bundle ACL reconstruction, and (4) after anatomic CTR single-bundle ACL reconstruction. Maximum anterior tibial translation in each group was measured. Lachman: No significant difference was observed between the AM and CTR reconstructions (n.s.) or between reconstruction and the intact ACL (3.4 ± 1.7 mm) (n.s.). Pivot Shift: Both the AM and CTR ACL reconstructions significantly reduced anterior translation relative to the ACL/menisci-deficient condition (lateral compartment: 8.9 ± 3.8 mm and 6.75 ± 4.6 mm vs. 17.25 ± 3.5 mm, respectively; P < 0.001 and medial compartment: -3.0 ± 5.3 mm vs. -3.7 ± 5.7 mm vs. 6.2 ± 6.7 mm, P < 0.05). There was also a significant difference between the AM (P < 0.001) and CTR (P < 0.05) ACL reconstructions and the intact ACL (2.8 ± 4.4 mm) for lateral compartment translation. Further, no difference was found between lateral or medial compartment translations in the AM versus CTR reconstructions (n.s.). It has been shown that there was no difference in the time-zero biomechanical stability between an anatomic anteromedial and anatomic central single-bundle ACL reconstruction. Given the current debate on the best anatomic ACL reconstruction technique, anatomic socket position in either the anteromedial or central locations provides similar time-zero biomechanics.

Research paper thumbnail of Robot-Assisted Unicompartmental Knee Arthroplasty

The Journal of Arthroplasty, 2010

Research paper thumbnail of Open Versus Arthroscopic Mosaicplasty of the Knee: A Cadaveric Assessment of Accuracy of Graft Placement Using Navigation

Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, Jan 5, 2015

The purpose of this study was to compare an open freehand mosaicplasty technique with an arthrosc... more The purpose of this study was to compare an open freehand mosaicplasty technique with an arthroscopic technique for the treatment of osteochondral lesions by measuring the instrument deviation, quantifying this deviation, and providing numerical information on the difference in the outcomes of these techniques. Four cadaveric knees were used. Reference markers were attached to the femur, tibia, and donor/recipient site guides. A total of 10 osteochondral grafts were harvested and inserted into recipient sites arthroscopically and 10 similar grafts were inserted freehand. The angles of graft removal and placement were calculated for each of the surgical groups compared. Ostensibly, a navigation system was used as an aid, to measure the graft placement parameters. Statistical analysis revealed that there was no statistically significant difference between the arthroscopic method and the freehand method regarding the angle of graft removal at the donor site (P = .162), recipient site p...

Research paper thumbnail of Fracture of the Medial Tubercle of the Posterior Process of the Talus: Magnetic Resonance Imaging Appearance with Clinical Follow-Up

Research paper thumbnail of Forefoot Injuries in Dancers

Clinics in Sports Medicine, 2008

Dancers, particularly ballet dancers, are artists and athletes. In dance, the choreographer acts ... more Dancers, particularly ballet dancers, are artists and athletes. In dance, the choreographer acts as a sculptor, using the dancer as a medium of expression. This often entails placing the dancer's body in positions that require extraordinary flexibility and movement, which requires controlled power and endurance. Ballet and other forms of dance can be highly demanding activities, with a lifetime injury incidence of up to 90%. Ballet is stressful particularly on the dancer's forefoot. The en pointe position of maximal plantarflexion through the forefoot, midfoot, and hindfoot requires tremendous flexibility and strength that only can be attained safely through many years of training. The forces experienced by the toes and metatarsals are extraordinary.

Research paper thumbnail of Comparing Stability of Different Single- and Double-Bundle Anterior Cruciate Ligament Reconstruction Techniques: A Cadaveric Study Using Navigation

Arthroscopy: The Journal of Arthroscopic & Related Surgery, 2010

Research paper thumbnail of Eleven-Year Results of the Anatomic Coated CFP Stem in Primary Total Hip Arthroplasty

The Journal of Arthroplasty, 2013

There is a paucity of intermediate term results relating to short stem prostheses. The current st... more There is a paucity of intermediate term results relating to short stem prostheses. The current study represents the longest follow-up results of the CFP prosthesis to the authors' best knowledge. Between January 1999 and December 2000, all total hip arthroplasty patients (n = 149), treated with this anatomic neck preserving stem in the authors' institution were enrolled in this study. After a mean follow-up time period of 11.2 years 117 patients were available for the follow-up examination. The mean HHS increased from 53 to 93. Overall, revision surgery was required in 11 patients (9.4%), with implant-associated complications noted in only five cases (4.3%). Aseptic loosening leading to implant removal was noted in four patients (3.4%). The current study's data suggest that the CFP implant, used in young patients undergoing primary total hip arthroplasty, is safe and provides excellent results after 11 years.

Research paper thumbnail of On the Horizon From the ORS

The Journal of the American Academy of Orthopaedic Surgeons

However, the synchrotron studies themselves also tell us what the capabilities of ABI really are ... more However, the synchrotron studies themselves also tell us what the capabilities of ABI really are and, therefore, what we should strive for from a system using a conventional x-ray source. For instance, we have found that ABI based on refraction information allows the visualization of soft tissues in intact specimens such as cadaveric knee (Figure 1), finger joints, and whole foot/ankle specimens while simultaneously producing high contrast in the calcified tissues. 5-7 The contrast for articular cartilage, including changes characteristic of ...

Research paper thumbnail of Paper # 129: Single Bundle vs. Double Bundle ACL Reconstruction in ACL/Meniscus Deficient Knees

Arthroscopy: The Journal of Arthroscopic & Related Surgery, 2011

Research paper thumbnail of Arthroscopic Mosaicplasty for Osteochondral Lesions of the Knee: Computer-Assisted Navigation Versus Freehand Technique

Arthroscopy: The Journal of Arthroscopic & Related Surgery, 2012

Research paper thumbnail of Effect of Tunnel Position and Graft Size in Single-Bundle Anterior Cruciate Ligament Reconstruction: An Evaluation of Time-Zero Knee Stability

Arthroscopy: The Journal of Arthroscopic & Related Surgery, 2011

Research paper thumbnail of Adjustable Cutting Blocks for Computer-Navigated Total Knee Arthroplasty

The Journal of Arthroplasty, 2010

Research paper thumbnail of Ankle Sprains and Instability in Dancers

Clinics in Sports Medicine, 2008

Research paper thumbnail of Arthroscopic-assisted Fluoroscopic Navigation for Retrograde Drilling of a Talar Osteochondral Lesion

Foot & Ankle International, 2009

Research paper thumbnail of Parathyroid Hormone (1-34) Augments Spinal Fusion, Fusion Mass Volume, and Fusion Mass Quality in a Rabbit Spinal Fusion Model

Research paper thumbnail of Clinical Tips: Retrograde Drilling Of Talar Osteochondral Defects

Foot & Ankle International, 2008

Contemporary methods of bone grafting osteochondral defects, in which the remaining overlying car... more Contemporary methods of bone grafting osteochondral defects, in which the remaining overlying cartilage is relatively well preserved, have inherent problems. The bony defects are often saucer-shaped and the cylindrical graft may not fill the void, leaving areas of cartilage with no underlying scaffold and obviating early weight bearing. Furthermore, to obtain a proper fill of the defect, tamping of the graft can cause excessive pressure and disruption of the overlying cartilage. In an effort to address these concerns, the authors propose the use of a biological viscous paste of calcium sulfate that hardens within 5 minutes when injected in a retrograde fashion into the talus. This confers a mechanical advantage of complete cystic fill of the cyst which allows early weight bearing. Calcium sulfate acts as an osteoconductive material that incorporates into host bone within 8 weeks. Donor site morbidity is eliminated using this system.

Research paper thumbnail of Pigmented Villonodular Synovitis about the Ankle: Two Case Reports

Foot & Ankle International, 2008

... 2008 May;29(5):527-33. Pigmented villonodular synovitis about the ankle: two case reports. He... more ... 2008 May;29(5):527-33. Pigmented villonodular synovitis about the ankle: two case reports. Heller SL, O'Loughlin PF, Di Carlo G, Mintz DN, Kennedy JG. Hospital for Special Surgery, New York, NY 10021, USA. PMID: 18510910 [PubMed - indexed for MEDLINE]. ...

Research paper thumbnail of Selection and Development of Preclinical Models in Fracture-Healing Research

The Journal of Bone and Joint Surgery (American), 2008

Animal fracture models have been extensively applied to preclinical research as a platform to ide... more Animal fracture models have been extensively applied to preclinical research as a platform to identify and characterize normal and abnormal physiological processes and to develop specific maneuvers that alter the biology and biomechanics being examined. The choice of animal model employed in a study bears a direct relationship to the specific intervention being analyzed. The animal models employed should be described clearly, control-group data should be established, and reproducibility should be defined from experiment to experiment and from institution to institution so that quantitative and qualitative outcomes can be reliably compared and contrasted to other related studies.

Research paper thumbnail of Navigated reconstruction of a tibial plateau compression fracture post-virtual reconstruction

Research paper thumbnail of Sequential versus automated cutting guides in computer-assisted total knee arthroplasty

Research paper thumbnail of Anteromedial versus central single-bundle graft position: which anatomic graft position to choose?

Knee Surgery, Sports Traumatology, Arthroscopy, 2012

To compare the time-zero stability of an anatomic anteromedial (AM) single-bundle ACL reconstruct... more To compare the time-zero stability of an anatomic anteromedial (AM) single-bundle ACL reconstruction to an anatomic central (CTR) single-bundle ACL reconstruction. Twelve (6 paired) hip to knee cadaveric specimens were studied. Using custom ACL computer navigation software, a Lachman test and a previously validated, navigated mechanized pivot shift test were performed on 4 separate experimental groups in each specimen: (1) intact ACL, (2) ACL deficient with total medial and lateral meniscectomy, (3) following anatomic AM single-bundle ACL reconstruction, and (4) after anatomic CTR single-bundle ACL reconstruction. Maximum anterior tibial translation in each group was measured. Lachman: No significant difference was observed between the AM and CTR reconstructions (n.s.) or between reconstruction and the intact ACL (3.4 ± 1.7 mm) (n.s.). Pivot Shift: Both the AM and CTR ACL reconstructions significantly reduced anterior translation relative to the ACL/menisci-deficient condition (lateral compartment: 8.9 ± 3.8 mm and 6.75 ± 4.6 mm vs. 17.25 ± 3.5 mm, respectively; P < 0.001 and medial compartment: -3.0 ± 5.3 mm vs. -3.7 ± 5.7 mm vs. 6.2 ± 6.7 mm, P < 0.05). There was also a significant difference between the AM (P < 0.001) and CTR (P < 0.05) ACL reconstructions and the intact ACL (2.8 ± 4.4 mm) for lateral compartment translation. Further, no difference was found between lateral or medial compartment translations in the AM versus CTR reconstructions (n.s.). It has been shown that there was no difference in the time-zero biomechanical stability between an anatomic anteromedial and anatomic central single-bundle ACL reconstruction. Given the current debate on the best anatomic ACL reconstruction technique, anatomic socket position in either the anteromedial or central locations provides similar time-zero biomechanics.

Research paper thumbnail of Robot-Assisted Unicompartmental Knee Arthroplasty

The Journal of Arthroplasty, 2010

Research paper thumbnail of Open Versus Arthroscopic Mosaicplasty of the Knee: A Cadaveric Assessment of Accuracy of Graft Placement Using Navigation

Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, Jan 5, 2015

The purpose of this study was to compare an open freehand mosaicplasty technique with an arthrosc... more The purpose of this study was to compare an open freehand mosaicplasty technique with an arthroscopic technique for the treatment of osteochondral lesions by measuring the instrument deviation, quantifying this deviation, and providing numerical information on the difference in the outcomes of these techniques. Four cadaveric knees were used. Reference markers were attached to the femur, tibia, and donor/recipient site guides. A total of 10 osteochondral grafts were harvested and inserted into recipient sites arthroscopically and 10 similar grafts were inserted freehand. The angles of graft removal and placement were calculated for each of the surgical groups compared. Ostensibly, a navigation system was used as an aid, to measure the graft placement parameters. Statistical analysis revealed that there was no statistically significant difference between the arthroscopic method and the freehand method regarding the angle of graft removal at the donor site (P = .162), recipient site p...