Jorge Aguilar | Universidad de Costa Rica (original) (raw)
Address: San José, San José, Costa Rica
less
Uploads
Papers by Jorge Aguilar
Journal of Nuclear Science and Technology
Revista Argentina De Urologia, Dec 1, 2011
Currently, most software projects around the world are small rather than large. Despite this, the... more Currently, most software projects around the world are small rather than large. Despite this, there are more methodologies, tools, frameworks, processes, and so on, for developing and managing large software projects than for small ones. Small software projects are important because they generate considerable resources. For example: apps (small mobile applications) generate around $25 billion dollars of revenue. This paper shows our findings regarding the size of the projects built by Mexican software development companies. We surveyed 107 Mexican companies and found that 92% of their developed projects are micro and small, and 8% are medium or large. In addition, according to our research, 84.1% of companies in Mexico are micro or small businesses.
Journal of Bacteriology, 2008
Pore-forming toxins are essential to the virulence of a wide variety of pathogenic bacteria. Gard... more Pore-forming toxins are essential to the virulence of a wide variety of pathogenic bacteria. Gardnerella vaginalis is a bacterial species associated with bacterial vaginosis (BV) and its significant adverse sequelae, including preterm birth and acquisition of human immunodeficiency virus. G. vaginalis makes a protein toxin that generates host immune responses and has been hypothesized to be involved in the pathogenesis of BV. We demonstrate that G. vaginalis produces a toxin (vaginolysin [VLY]) that is a member of the cholesterol-dependent cytolysin (CDC) family, most closely related to intermedilysin from Streptococcus intermedius . Consistent with this predicted relationship, VLY lyses target cells in a species-specific manner, dependent upon the complement regulatory molecule CD59. In addition to causing erythrocyte lysis, VLY activates the conserved epithelial p38 mitogen-activated protein kinase pathway and induces interleukin-8 production by human epithelial cells. Transfectio...
Earth and Planetary Science Letters, 2009
... Author Contact Information , E-mail The Corresponding Author , M. Calvet b , S. Brichau c , A... more ... Author Contact Information , E-mail The Corresponding Author , M. Calvet b , S. Brichau c , A. Carter c , J.-P. Aguilar d and ... Furthermore, in post-Davisian times the paradigms of continuity and steady state in Earth processes (eg Willet and Brandon, 2002) have gained preference ...
Journal of Nuclear Science and Technology
Revista Argentina De Urologia, Dec 1, 2011
Currently, most software projects around the world are small rather than large. Despite this, the... more Currently, most software projects around the world are small rather than large. Despite this, there are more methodologies, tools, frameworks, processes, and so on, for developing and managing large software projects than for small ones. Small software projects are important because they generate considerable resources. For example: apps (small mobile applications) generate around $25 billion dollars of revenue. This paper shows our findings regarding the size of the projects built by Mexican software development companies. We surveyed 107 Mexican companies and found that 92% of their developed projects are micro and small, and 8% are medium or large. In addition, according to our research, 84.1% of companies in Mexico are micro or small businesses.
Journal of Bacteriology, 2008
Pore-forming toxins are essential to the virulence of a wide variety of pathogenic bacteria. Gard... more Pore-forming toxins are essential to the virulence of a wide variety of pathogenic bacteria. Gardnerella vaginalis is a bacterial species associated with bacterial vaginosis (BV) and its significant adverse sequelae, including preterm birth and acquisition of human immunodeficiency virus. G. vaginalis makes a protein toxin that generates host immune responses and has been hypothesized to be involved in the pathogenesis of BV. We demonstrate that G. vaginalis produces a toxin (vaginolysin [VLY]) that is a member of the cholesterol-dependent cytolysin (CDC) family, most closely related to intermedilysin from Streptococcus intermedius . Consistent with this predicted relationship, VLY lyses target cells in a species-specific manner, dependent upon the complement regulatory molecule CD59. In addition to causing erythrocyte lysis, VLY activates the conserved epithelial p38 mitogen-activated protein kinase pathway and induces interleukin-8 production by human epithelial cells. Transfectio...
Earth and Planetary Science Letters, 2009
... Author Contact Information , E-mail The Corresponding Author , M. Calvet b , S. Brichau c , A... more ... Author Contact Information , E-mail The Corresponding Author , M. Calvet b , S. Brichau c , A. Carter c , J.-P. Aguilar d and ... Furthermore, in post-Davisian times the paradigms of continuity and steady state in Earth processes (eg Willet and Brandon, 2002) have gained preference ...