Fernando Mut | Universidad de la República (Uruguay) (original) (raw)

Papers by Fernando Mut

Revista uruguaya de cardiología, Sep 1, 2009

Revista uruguaya de cardiología, 2008

Journal of Orthopaedic Surgery and Research

Purpose The aim of this systematic review was to present the current evidence on the clinical use... more Purpose The aim of this systematic review was to present the current evidence on the clinical use of single-photon emission computed tomography/computed tomography (SPECT/CT) in the evaluation of noninfected painful knees after knee arthroplasty. Methods Embase, PubMed, Google Scholar, Ovid, Scopus, Science Direct and the Cochrane Database of Systematic Reviews were searched from database inception to May 2022 following the PRISMA guidelines. As a primary outcome, we defined the role of SPECT/CT in the diagnostic approach to noninfected painful knee arthroplasty; as a secondary objective, we described the noninfection-related factors linked to painful knee arthroplasty. Pooled sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, diagnostic odds ratio values and other indicators were calculated; receiver operating characteristic (ROC) curve analysis results and a summary of the areas under the curve (AUCs) from the included studies were reported. A Fagan pl...

Nuclear Medicine Communications, Mar 1, 1998

Society of Nuclear Medicine Annual Meeting Abstracts, May 1, 2010

Journal of Nuclear Cardiology, Mar 1, 2005

Background: Adenosine SPECT myocardial perfusion imaging provides prognostic information in patie... more Background: Adenosine SPECT myocardial perfusion imaging provides prognostic information in patients with suspected coronary artery disease (CAD); limited data however, are available on the incremental prognostic value of this modality in high risk patients with angiographically documented coronary artery anatomy. Therefore, the purpose of this investigation was 1) to evaluate the prognostic value of adenosine SPECT myocardial perfusion imaging for predicting adverse events in a high risk patient population with coronary angiography and 2) to compare the prognostic value of adenosine SPECT with that of cardiac catheterization data. Methods: We studied a total of 662 patients who underwent cardiac catheterization and adenosine SPECT imaging. The mean follow up was 2.3 years for cardiovascular death(CVD). Using Cox proportional hazards regression models, we 1) examined the relationship between adenosine SPECT and CVD after adjusting for a previously-validated baseline clinical index and, 2) compared the prognostic value of adenosine SPECT with that of angiographic data (number of diseased vessels). Results: During the follow-up period, 86 patients died from cardiovascular causes. After adjusting for clinical information, adenosine SPECT provided significant incremental prognostic information: incremental Chi-sq ϭ 6.27; p ϭ 0.012 for CVD. Furthermore, adenosine SPECT provided prognostic information above that provided by clinical and cardiac catheterization combined: incremental Chi-sq ϭ 4.5; p ϭ 0.03 for CVD. Conclusions: Adenosine SPECT imaging adds significant incremental prognostic information to clinical and cardiac catheterization data for the prediction of cardiovascular death in high-risk patients with angiographically documented CAD. Furthermore, adenosine SPECT imaging can further risk-stratify patients even after considering clinical and cardiac catheterization data.

Clinical Nuclear Medicine, Jun 1, 1997

ABSTRACT The authors report on a patient with a malignant papiliary thyroid nodule that was &... more ABSTRACT The authors report on a patient with a malignant papiliary thyroid nodule that was ''cold'' with Tc-99m pertechnetate and evaluated by double-phase thyroid scintigraphy with Tc-99m sestamibi (MIBI). The images were taken at 15 minutes and 2 hours postinjection. Although nodular MIBI uptake on the early scan was present, it was less intense than the extranodular thyroid tissue. The delayed image showed an inverse relation of uptake, being more intense in the nodular lesion. This scintigraphic pattern could be explained by a slower washout rate of the malignant lesion. However, delayed tracer accumulation cannot be excluded.

Journal of Nuclear Cardiology, Feb 22, 2016

Hybrid imaging using PET/CT have various applications in cardiology. Anatomy, physiology or both ... more Hybrid imaging using PET/CT have various applications in cardiology. Anatomy, physiology or both can be evaluated. Routine attenuation correction can be performed and improve accuracy for nuclear cardiology studies. The extent of availability and utilization of hybrid imaging technology worldwide is currently unknown. The International Atomic Energy Agency (IAEA) in cooperation with QUANTA performed a web-based survey among physicians working with nuclear imaging to evaluate the current availability of hybrid imaging and its use for nuclear cardiology (NC). Contact e mails of physicians working in the field of nuclear cardiology were available from a data base at the human health department of the IAEA in Vienna, Austria and an international network of nuclear cardiologist at QUANTA in Curitiba, Brazil. Data from 80 countries in both high-income countries (HIC, n=16) and low-and-middle income countries (LMIC, n=64) representing all world regions, was obtained. At the country level, PET/CT is available in all world regions being widely available in North and Latin America, Europe, Asia and Oceania with a heterogeneous availability in Africa. Nevertheless, only 22.4% of centers in HIC and 10.9% in LMIC that have PET/CT available use it for NC applications. These data will help us to work with scientific societies and institutions to design strategies to diffuse information for physicians so they can take full advantage of PET/CT technology to obtain additional information that could impact patient care.

Journal of Nuclear Cardiology, Feb 1, 1999

Revista española de medicina nuclear e imagen molecular, Jul 1, 2018

Journal of Nuclear Cardiology, 2001

Clinical Nuclear Medicine, Oct 1, 1998

Two cases of malignant melanoma (primary and metastatic lesions) imaged with Tc-99m tetrofosmin a... more Two cases of malignant melanoma (primary and metastatic lesions) imaged with Tc-99m tetrofosmin are reported. One patient showed intense uptake in a primary skin lesion of the thorax, and the other patient had accumulation in skin, cerebellum, breast, and lymph node metastases. Like Tc-99m MIBI, Tc-99m tetrofosmin imaging may be of clinical relevance in the evaluation of suspicious skin lesions and in patients with known cutaneous malignant melanoma in the assessment of recurrent disease during follow-up evaluation.

Melanoma Research, Aug 1, 1998

Initial reports suggest that 99mTc-methoxyisobutylisonitrile (MIBI) scanning may be of clinical v... more Initial reports suggest that 99mTc-methoxyisobutylisonitrile (MIBI) scanning may be of clinical value in staging patients with malignant melanoma. We carried out a study to evaluate the potential of this technique in the detection of recurrent disease. Whole-body 99mTC-MIBI scans were performed in 81 patients with a history of a surgically excised MM: 28 with known recurrent lesions and 53 during follow-up without evidence of disease. Images started 10 min post-injection, using a dose of 740 MBq. Diagnoses were confirmed by cytological/histological examination or at least one conventional imaging modality. Blinded interpretations of the MIBI scans were performed. Whole-body MIBI scanning correctly detected 68 (92%) of 74 metastatic lesions in the following sites: regional lymph nodes (n=23), non-regional lymph nodes (n=10), skin (n=16), brain/cerebellum (n=6), lung (n=8), bone (n=4) and breast (n=1). The technique failed to detect three subcutaneous regressive lesions (&amp;amp;amp;lt; 1 cm), one liver metastasis, one spleen metastasis and a case of multiple small lesions of the duodenal mucous membrane. In 14 patients the procedure detected previously unknown metastatic lesions. These results suggest that 99mTc-MIBI scanning is an effective imaging modality for whole-body screening of metastatic disease in malignant melanoma patients with the potential to influence treatment planning.

The Journal of Nuclear Medicine, Mar 12, 2015

Journal of the American College of Cardiology

World journal of nuclear medicine, 2002

Arquivos Brasileiros de Cardiologia, 2021

Artigo Original Cerci et al. Diagnóstico de Doenças Cardíacas na América Latina durante a COVID-1... more Artigo Original Cerci et al. Diagnóstico de Doenças Cardíacas na América Latina durante a COVID-19 Resumo Fundamento: A pandemia de COVID-19 interferiu na prestação de atendimento a doenças cardiovasculares na América Latina. No entanto, o efeito da pandemia nos volumes de procedimentos cardíacos diagnósticos ainda não foi quantificado. Objetivo: Avaliar (1) o impacto de COVID-19 nos volumes de diagnóstico cardíaco na América Latina e (2) determinar sua relação com a incidência de casos de COVID-19 e as medidas de distanciamento social. Métodos: A International Atomic Energy Agency realizou uma pesquisa mundial avaliando mudanças nos volumes diagnósticos cardíacos decorrentes da COVID-19. Foram obtidos os volumes diagnósticos cardíacos dos locais participantes para março e abril de 2020 e comparados com março de 2019. Foram coletados dados de distanciamento social a partir dos Relatórios de mobilidade da comunidade de Google e a incidência de COVID-19 por país a partir de Our World in Data. Resultados: Foram realizadas pesquisas em 194 centros que realizam procedimentos diagnósticos cardíacos, em 19 países da América Latina. Em comparação com o mês de março de 2019, os volumes dos procedimentos diagnósticos cardíacos diminuíram 36% em março de 2020 e 82% em abril de 2020.As maiores reduções ocorreram em relação aos testes de estresse ecocardiográfico (91%), testes ergométricos de esteira (88%) e escore de cálcio por tomografia computadorizada (87%), com pequenas variações entre as sub-regiões da América Latina. As mudanças em padrões de distanciamento social (p < 0,001) estavam mais fortemente associadas com a redução do volume do que a incidência de COVID-19 (p = 0,003). Conclusões: A COVID-19 foi associada a uma redução significativa de procedimentos diagnósticos cardíacos na América Latina, a qual foi mais relacionada ao distanciamento social do que ao aumento da incidência da COVID-19. São necessários melhor equilíbrio e timing de medidas de distanciamento social e planejamento para manter o acesso ao atendimento médico durante um surto pandêmico, especialmente em regiões com alta mortalidade cardiovascular.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2021

Data and Analysis An analysis of data collected throughout 2020 on the status and growth of NM in... more Data and Analysis An analysis of data collected throughout 2020 on the status and growth of NM in the countries of the LAC region was carried out by the Nuclear Medicine and Diagnostic Imaging Section of the IAEA and compared to that collected by the IAEA in 2014 and