Henrique Campos | Universidade do Estado do Rio Grande do Norte (original) (raw)

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Papers by Henrique Campos

International Journal of Antimicrobial Agents, 2007

Nosocomial pneumonia caused by multidrug-resistant (MDR) Pseudomonas aeruginosa is becoming incre... more Nosocomial pneumonia caused by multidrug-resistant (MDR) Pseudomonas aeruginosa is becoming increasingly prevalent throughout the world. The use of polymyxins to treat these infections has greatly increased. We analysed 74 patients with nosocomial pneumonia caused by MDR P. aeruginosa who were treated with polymyxin B. A favourable outcome was observed in 35 patients (47.3%). A case-control study was performed to assess the variables associated with an unfavourable outcome. The presence of acute respiratory distress syndrome (odds ratio (OR) = 11.29, 95% confidence interval (CI) 2.64-48.22; P = 0.001) and septic shock (OR = 4.81, 95% CI 1.42-16.25; P = 0.01) were independently associated with an unfavourable outcome in patients with nosocomial pneumonia due to MDR P. aeruginosa. Our study demonstrated that polymyxin B is a reliable antimicrobial drug, but only as salvage therapy, for nosocomial pneumonia caused by MDR P. aeruginosa.

International Journal of Antimicrobial Agents, 2007

Nosocomial pneumonia caused by multidrug-resistant (MDR) Pseudomonas aeruginosa is becoming incre... more Nosocomial pneumonia caused by multidrug-resistant (MDR) Pseudomonas aeruginosa is becoming increasingly prevalent throughout the world. The use of polymyxins to treat these infections has greatly increased. We analysed 74 patients with nosocomial pneumonia caused by MDR P. aeruginosa who were treated with polymyxin B. A favourable outcome was observed in 35 patients (47.3%). A case-control study was performed to assess the variables associated with an unfavourable outcome. The presence of acute respiratory distress syndrome (odds ratio (OR) = 11.29, 95% confidence interval (CI) 2.64-48.22; P = 0.001) and septic shock (OR = 4.81, 95% CI 1.42-16.25; P = 0.01) were independently associated with an unfavourable outcome in patients with nosocomial pneumonia due to MDR P. aeruginosa. Our study demonstrated that polymyxin B is a reliable antimicrobial drug, but only as salvage therapy, for nosocomial pneumonia caused by MDR P. aeruginosa.

This paper investigates the economic advantages, which appear to the supply chains that adopt the... more This paper investigates the economic advantages, which appear to the supply chains that adopt the Efficient Consumer Response (ECR), and also the actions needed to obtain those advantages. The guidelines are found in a dynamic model and its optimality conditions. The instrumental is used to model a supply chain that adopts the ECR. The purpose is to determine the impacts on the financial management and on the structure of the retail market that arise with the ECR adoption. It's shown up the inter-relations among the several aspects that must be considered in the implementation of a supply partnership.

Journal of Critical Care, 2009

Objectives: The aim of this study was to evaluate the risk factors and attributable mortality ass... more Objectives: The aim of this study was to evaluate the risk factors and attributable mortality associated with imipenem-resistant Pseudomonas aeruginosa (IRPA) infections in a medical-surgical intensive care unit (ICU). Methods: A retrospective case-control study was carried out at a 16-bed medical-surgical ICU in a 780bed, university-affiliated hospital. All patients admitted from January 1, 2003, to December 31, 2004, who had nosocomial infection caused by IRPA, were included in the study. Results: Imipenem-resistant P. aeruginosa was recovered from 63 patients during the study period. One hundred eighty-two controls were matched with cases by period of admission, age, and time at risk. Urinary tract (34.9%) and respiratory tract (22.2%) were the main sources of IRPA isolation. In multivariate analysis, a previous stay in the ICU (odds ratio, 3.54; 95% confidence interval [CI], 1.29-9.73; P = .03) was the only independent risk factor for IRPA infection. The in-hospital mortality rate among case patients was 49% (31 of 63) compared with 33% (61 of 182) for control patients (odds ratio, 1.92; 95% CI, 1.07-3.44; P = .02). Thus, we had an attributable mortality of 16% (95% CI, 9.74%-22.3%; P = .03). Conclusions: Our study suggests that IRPA infections are strongly related to previous ICU stay, and that IRPA infections significantly increase mortality in those critical patients.

Revista Brasileira De Coloproctologia, 2006

RESUMO: O tumor desmóide (TD) é uma neoplasia benigna, que se origina de estruturas fasciais ou m... more RESUMO: O tumor desmóide (TD) é uma neoplasia benigna, que se origina de estruturas fasciais ou músculo-aponeuróticas, constituída por proliferação fibroblástica. Ocorre em 4 a 13% dos pacientes com polipose adenomatosa familiar (FAP). Apesar de histologicamente benignos, os TD têm comportamento maligno, sendo localmente invasivos e com elevada recorrência após ressecção. Os autores relatam um caso de tumor desmóide tratado cirurgicamente no Hospital Governador Israel Pinheiro -IPSEMG e fazem revisão da literatura sobre o tratamento. Descritores: Tumores desmóides, tamoxifeno, polipose adenomatosa familiar TUMOR DESMÓIDE TRATADO COM TAMOXIFENO: RELATO DE CASO CÔRTES BJW, LEITE SMO, CAMPOS MHR, OLIVEIRA LA. Tumor Desmóide Tratado com Tamoxifeno: Relato de Caso. Rev bras Coloproct, 2006;26(1):61-64.

Purpose: to make a differential diagnosis in regard to breast carcinoma and to evaluate diagnosti... more Purpose: to make a differential diagnosis in regard to breast carcinoma and to evaluate diagnostic and clinical methods in the treatment of breast tuberculosis and the follow-up after adequate treatment. Patients and Methods: three patients with breast tuberculosis were observed from March 2001 to March 2002; the first two were hospitalized at our Mastology Department and the third patient was treated at a private clinic. The clinical signs and symptoms, laboratory findings, response to therapy and follow-up were evaluated. Results: the average age of the patients was 40.6 years. The most frequent signs and symptoms were pain and breast tumor. In two patients the presumptive diagnosis was based on the clinical findings, on the histological findings (granulomatous inflammatory process), and on the therapeutic response to tuberculostatic drugs. Only one patient had a microbiological diagnosis, as Koch's bacillus was identified in a sample of her breast tissue. Treatment with a triple tuberculostatic regimen, including rifampin, isoniazid and pyrazinamide, led to the regression of the lesions. Conclusion: primary breast tuberculosis, a rare occurrence which may present clinically as a breast nodule and radiologically as carcinoma, should be taken into account when making the differential diagnosis of patients presenting with mammary mass.

Purpose: to make a differential diagnosis in regard to breast carcinoma and to evaluate diagnosti... more Purpose: to make a differential diagnosis in regard to breast carcinoma and to evaluate diagnostic and clinical methods in the treatment of breast tuberculosis and the follow-up after adequate treatment. Patients and Methods: three patients with breast tuberculosis were observed from March 2001 to March 2002; the first two were hospitalized at our Mastology Department and the third patient was treated at a private clinic. The clinical signs and symptoms, laboratory findings, response to therapy and follow-up were evaluated. Results: the average age of the patients was 40.6 years. The most frequent signs and symptoms were pain and breast tumor. In two patients the presumptive diagnosis was based on the clinical findings, on the histological findings (granulomatous inflammatory process), and on the therapeutic response to tuberculostatic drugs. Only one patient had a microbiological diagnosis, as Koch's bacillus was identified in a sample of her breast tissue. Treatment with a triple tuberculostatic regimen, including rifampin, isoniazid and pyrazinamide, led to the regression of the lesions. Conclusion: primary breast tuberculosis, a rare occurrence which may present clinically as a breast nodule and radiologically as carcinoma, should be taken into account when making the differential diagnosis of patients presenting with mammary mass.

This paper addresses a process for identifying system use cases from business models. The propose... more This paper addresses a process for identifying system use cases from business models. The proposed process is comprised of four phases supported by the DoD Std 2167 A. It suggests the use of UML notation during the model elaboration. In order to verify the process, it was applied on an actual project named Amazon Integration and Cooperation for Modernization of Hydrological Monitoring, under the development of the Brazilian Aeronautics Institute of Technology (Instituto Tecnológico de Aeronáutica -ITA). The main contributions of this paper are the proposed system use cases identification process and the validation procedure performed, comparing the obtained results with those results from a traditional approach.

Project between ANA and Brazilian Aeronautics Institute of Technology (ITA). The integration proc... more Project between ANA and Brazilian Aeronautics Institute of Technology (ITA). The integration process started with a detailed analysis of four existing databases, followed by logical modeling elaboration and integration. Its major contributions are the description of main processes, documentations, model auditing, and human resources involved. At the end, the best practices used for applying main data modeling and database design techniques together with a successful use of a modeling tools are also presented.

This paper tackles the use of software testing techniques for Web-Application non-functional requ... more This paper tackles the use of software testing techniques for Web-Application non-functional requirements. It also shows load and performance testing application in a case study. At the end, a successful new approach for the navigability testing for Web-Applications is proposed.

International Journal of Antimicrobial Agents, 2007

Nosocomial pneumonia caused by multidrug-resistant (MDR) Pseudomonas aeruginosa is becoming incre... more Nosocomial pneumonia caused by multidrug-resistant (MDR) Pseudomonas aeruginosa is becoming increasingly prevalent throughout the world. The use of polymyxins to treat these infections has greatly increased. We analysed 74 patients with nosocomial pneumonia caused by MDR P. aeruginosa who were treated with polymyxin B. A favourable outcome was observed in 35 patients (47.3%). A case-control study was performed to assess the variables associated with an unfavourable outcome. The presence of acute respiratory distress syndrome (odds ratio (OR) = 11.29, 95% confidence interval (CI) 2.64-48.22; P = 0.001) and septic shock (OR = 4.81, 95% CI 1.42-16.25; P = 0.01) were independently associated with an unfavourable outcome in patients with nosocomial pneumonia due to MDR P. aeruginosa. Our study demonstrated that polymyxin B is a reliable antimicrobial drug, but only as salvage therapy, for nosocomial pneumonia caused by MDR P. aeruginosa.

International Journal of Antimicrobial Agents, 2007

Nosocomial pneumonia caused by multidrug-resistant (MDR) Pseudomonas aeruginosa is becoming incre... more Nosocomial pneumonia caused by multidrug-resistant (MDR) Pseudomonas aeruginosa is becoming increasingly prevalent throughout the world. The use of polymyxins to treat these infections has greatly increased. We analysed 74 patients with nosocomial pneumonia caused by MDR P. aeruginosa who were treated with polymyxin B. A favourable outcome was observed in 35 patients (47.3%). A case-control study was performed to assess the variables associated with an unfavourable outcome. The presence of acute respiratory distress syndrome (odds ratio (OR) = 11.29, 95% confidence interval (CI) 2.64-48.22; P = 0.001) and septic shock (OR = 4.81, 95% CI 1.42-16.25; P = 0.01) were independently associated with an unfavourable outcome in patients with nosocomial pneumonia due to MDR P. aeruginosa. Our study demonstrated that polymyxin B is a reliable antimicrobial drug, but only as salvage therapy, for nosocomial pneumonia caused by MDR P. aeruginosa.

This paper investigates the economic advantages, which appear to the supply chains that adopt the... more This paper investigates the economic advantages, which appear to the supply chains that adopt the Efficient Consumer Response (ECR), and also the actions needed to obtain those advantages. The guidelines are found in a dynamic model and its optimality conditions. The instrumental is used to model a supply chain that adopts the ECR. The purpose is to determine the impacts on the financial management and on the structure of the retail market that arise with the ECR adoption. It's shown up the inter-relations among the several aspects that must be considered in the implementation of a supply partnership.

Journal of Critical Care, 2009

Objectives: The aim of this study was to evaluate the risk factors and attributable mortality ass... more Objectives: The aim of this study was to evaluate the risk factors and attributable mortality associated with imipenem-resistant Pseudomonas aeruginosa (IRPA) infections in a medical-surgical intensive care unit (ICU). Methods: A retrospective case-control study was carried out at a 16-bed medical-surgical ICU in a 780bed, university-affiliated hospital. All patients admitted from January 1, 2003, to December 31, 2004, who had nosocomial infection caused by IRPA, were included in the study. Results: Imipenem-resistant P. aeruginosa was recovered from 63 patients during the study period. One hundred eighty-two controls were matched with cases by period of admission, age, and time at risk. Urinary tract (34.9%) and respiratory tract (22.2%) were the main sources of IRPA isolation. In multivariate analysis, a previous stay in the ICU (odds ratio, 3.54; 95% confidence interval [CI], 1.29-9.73; P = .03) was the only independent risk factor for IRPA infection. The in-hospital mortality rate among case patients was 49% (31 of 63) compared with 33% (61 of 182) for control patients (odds ratio, 1.92; 95% CI, 1.07-3.44; P = .02). Thus, we had an attributable mortality of 16% (95% CI, 9.74%-22.3%; P = .03). Conclusions: Our study suggests that IRPA infections are strongly related to previous ICU stay, and that IRPA infections significantly increase mortality in those critical patients.

Revista Brasileira De Coloproctologia, 2006

RESUMO: O tumor desmóide (TD) é uma neoplasia benigna, que se origina de estruturas fasciais ou m... more RESUMO: O tumor desmóide (TD) é uma neoplasia benigna, que se origina de estruturas fasciais ou músculo-aponeuróticas, constituída por proliferação fibroblástica. Ocorre em 4 a 13% dos pacientes com polipose adenomatosa familiar (FAP). Apesar de histologicamente benignos, os TD têm comportamento maligno, sendo localmente invasivos e com elevada recorrência após ressecção. Os autores relatam um caso de tumor desmóide tratado cirurgicamente no Hospital Governador Israel Pinheiro -IPSEMG e fazem revisão da literatura sobre o tratamento. Descritores: Tumores desmóides, tamoxifeno, polipose adenomatosa familiar TUMOR DESMÓIDE TRATADO COM TAMOXIFENO: RELATO DE CASO CÔRTES BJW, LEITE SMO, CAMPOS MHR, OLIVEIRA LA. Tumor Desmóide Tratado com Tamoxifeno: Relato de Caso. Rev bras Coloproct, 2006;26(1):61-64.

Purpose: to make a differential diagnosis in regard to breast carcinoma and to evaluate diagnosti... more Purpose: to make a differential diagnosis in regard to breast carcinoma and to evaluate diagnostic and clinical methods in the treatment of breast tuberculosis and the follow-up after adequate treatment. Patients and Methods: three patients with breast tuberculosis were observed from March 2001 to March 2002; the first two were hospitalized at our Mastology Department and the third patient was treated at a private clinic. The clinical signs and symptoms, laboratory findings, response to therapy and follow-up were evaluated. Results: the average age of the patients was 40.6 years. The most frequent signs and symptoms were pain and breast tumor. In two patients the presumptive diagnosis was based on the clinical findings, on the histological findings (granulomatous inflammatory process), and on the therapeutic response to tuberculostatic drugs. Only one patient had a microbiological diagnosis, as Koch's bacillus was identified in a sample of her breast tissue. Treatment with a triple tuberculostatic regimen, including rifampin, isoniazid and pyrazinamide, led to the regression of the lesions. Conclusion: primary breast tuberculosis, a rare occurrence which may present clinically as a breast nodule and radiologically as carcinoma, should be taken into account when making the differential diagnosis of patients presenting with mammary mass.

Purpose: to make a differential diagnosis in regard to breast carcinoma and to evaluate diagnosti... more Purpose: to make a differential diagnosis in regard to breast carcinoma and to evaluate diagnostic and clinical methods in the treatment of breast tuberculosis and the follow-up after adequate treatment. Patients and Methods: three patients with breast tuberculosis were observed from March 2001 to March 2002; the first two were hospitalized at our Mastology Department and the third patient was treated at a private clinic. The clinical signs and symptoms, laboratory findings, response to therapy and follow-up were evaluated. Results: the average age of the patients was 40.6 years. The most frequent signs and symptoms were pain and breast tumor. In two patients the presumptive diagnosis was based on the clinical findings, on the histological findings (granulomatous inflammatory process), and on the therapeutic response to tuberculostatic drugs. Only one patient had a microbiological diagnosis, as Koch's bacillus was identified in a sample of her breast tissue. Treatment with a triple tuberculostatic regimen, including rifampin, isoniazid and pyrazinamide, led to the regression of the lesions. Conclusion: primary breast tuberculosis, a rare occurrence which may present clinically as a breast nodule and radiologically as carcinoma, should be taken into account when making the differential diagnosis of patients presenting with mammary mass.

This paper addresses a process for identifying system use cases from business models. The propose... more This paper addresses a process for identifying system use cases from business models. The proposed process is comprised of four phases supported by the DoD Std 2167 A. It suggests the use of UML notation during the model elaboration. In order to verify the process, it was applied on an actual project named Amazon Integration and Cooperation for Modernization of Hydrological Monitoring, under the development of the Brazilian Aeronautics Institute of Technology (Instituto Tecnológico de Aeronáutica -ITA). The main contributions of this paper are the proposed system use cases identification process and the validation procedure performed, comparing the obtained results with those results from a traditional approach.

Project between ANA and Brazilian Aeronautics Institute of Technology (ITA). The integration proc... more Project between ANA and Brazilian Aeronautics Institute of Technology (ITA). The integration process started with a detailed analysis of four existing databases, followed by logical modeling elaboration and integration. Its major contributions are the description of main processes, documentations, model auditing, and human resources involved. At the end, the best practices used for applying main data modeling and database design techniques together with a successful use of a modeling tools are also presented.

This paper tackles the use of software testing techniques for Web-Application non-functional requ... more This paper tackles the use of software testing techniques for Web-Application non-functional requirements. It also shows load and performance testing application in a case study. At the end, a successful new approach for the navigability testing for Web-Applications is proposed.