Claudio Teloken | Universidade Federal de Ciências da Saúde de Porto Alegre (original) (raw)

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Research paper thumbnail of Salud y calidad de vida en urología: Aspectos en urología general y oncológica

Archivos Españoles de Urología (Ed. impresa), 2009

Research paper thumbnail of Multi-Institutional Validation of Vasectomy Reversal Predictor

The Journal of Urology, 2006

Research paper thumbnail of Plaque incision and grafting represents the best surgical approach to the Peyronie’s disease patient: Pro

Current Sexual Health Reports, 2006

Research paper thumbnail of 7006 Effect of baseline characteristics on prostate cancer rates and risk reduction in the Reduction by Dutasteride of prostate Cancer Events REDUCE) trial

European Journal of Cancer Supplements, 2009

Research paper thumbnail of ATROPINE ROLE IN THE PHARMACOLOGICAL ERECTION TEST: STUDY OF 228 PATIENTS

The Journal of Urology, 1997

We determined the efficacy of atropine sulfate combined with papaverine hydrochloride, prostaglan... more We determined the efficacy of atropine sulfate combined with papaverine hydrochloride, prostaglandin E1 and phentolamine mesylate in the pharmacological erection test. A total of 230 consecutive patients with erectile dysfunction was randomized for pharmacological erection test and received an intracorporeal combination of 50 mg. papaverine hydrochloride, 10 micrograms. prostaglandin E1, 0.2 mg. phentolamine mesylate and 0.075 mg. of atropine sulfate (group 1), or the same combination without atropine sulfate (group 2). Erectile response was evaluated subjectively and by intracorporeal pressure measurement. In group 1, 40 patients (35.1%) showed only tumescence, and 22 (19.3%) had poor erection. In group 2, 45 patients (39.5%) had tumescence and 17 (14.9%) poor erection. In both groups 52 patients (45.6%) had rigid erection. There was no statistically significant difference regarding erectile response and intracorporeal pressure. The addition of atropine sulfate did not improve results of the pharmacological erection test when combined with 50 mg. papverine hydrochloride, 10 micrograms, prostaglandin E1, and 0.2 mg. phentolamine mesylate.

Research paper thumbnail of Standards for Clinical Trials in Male Sexual Dysfunctions

Journal of Sexual Medicine, 2010

Research paper thumbnail of Magnetic Spheres as Foreign Body into the Bladder

The Journal of Sexual Medicine, 2012

Research paper thumbnail of Overactive bladder: prevalence and implications in Brazil

European urology, 2006

To assess overactive bladder (OAB) prevalence, associated factors and implications in a young pop... more To assess overactive bladder (OAB) prevalence, associated factors and implications in a young population. An independent population-based study was carried out. A self-applicative questionnaire covering urinary symptoms, coping strategies, quality of life and treatment seeking behavior was developed. A total of 848 subjects between 15 and 55 years completed the questionnaire. The overall prevalence of OAB was 18.9%. Women were significantly more affected than men (p = 0.001). All age groups were equally affected (p = 0.152). Subjects with OAB reported significant impairment on household chores (p = 0.009), physical activities (p = 0.016), sleep (p < 0.001), work (p < 0.001), social life (p < 0.001) and sexual life (p < 0.001). In addition, OAB individuals present higher prevalence of depression (p = 0.036), anxiety (p < 0.001), shame (p < 0.001) and tiredness (p < 0.001) OAB was independently associated to sexual life impairment (OR = 3.36, 95% CI=1.20-9.39). On...

Research paper thumbnail of Usefulness of prostate-specific antigen (PSA) rise as a marker of prostate cancer in men treated with dutasteride: lessons from the REDUCE study

BJU international, 2012

To determine if dutasteride-treated men can be monitored safely and adequately for prostate cance... more To determine if dutasteride-treated men can be monitored safely and adequately for prostate cancer based on data from the Reduction by Dutasteride in Prostate Cancer Events (REDUCE) study. To analyse whether the use of treatment-specific criteria for repeat biopsy maintains the usefulness of prostate-specific antigen (PSA) level for detecting high grade cancers. The REDUCE study was a randomized, double-blind, placebo-controlled investigation of whether dutasteride (0.5 mg/day) reduced the risk of biopsy-detectable prostate cancer in men with a previous negative biopsy. The usefulness of PSA was evaluated using biopsy thresholds defined by National Comprehensive Cancer Network guidelines in the placebo group and any rise in PSA from nadir (the lowest PSA level achieved while in the study) in the dutasteride group. The number of cancers detected on biopsy in the absence of increased/suspicious PSA level as well as sensitivity, specificity, positive predictive value and negative predi...

Research paper thumbnail of Oral Treatment of Peyronie’s Disease

Current Clinical Urology, 2007

This chapter reviews the possible effectiveness of oral agents as an option for treatment of Peyr... more This chapter reviews the possible effectiveness of oral agents as an option for treatment of Peyronie’s disease (PD). We present the rationale for use of these drugs and base our recommendations on levels of published evidence and the report by the International Consultation on Urological Diseases. A definitive and ideal medical therapy for PD has yet to be established and will not be until we completely understand the trigger mechanism and the maintenance process of fibrosis in the tunica albuginea. Several oral substances have been proposed with promises of success; however, these agents appear to lack robust scientific support for their benefit. Until new evidence is available, the indications for oral treatment in PD are recent onset of disease, painful plaque, and unstable plaque. An early trial of inexpensive, safe, and well-tolerated oral therapy may be offered with limited enthusiasm for a positive outcome.

Research paper thumbnail of Estudio prospectivo que compara laparoscopia y cirugía abierta para el tratamiento de cálculos ureterales impactados

Revue Neurologique, 2009

Introduction and objectivesTo investigate two ureterolithotomy approaches for treatment of large ... more Introduction and objectivesTo investigate two ureterolithotomy approaches for treatment of large and impacted upper ureteral stones, we prospectively evaluated the perioperative features of consecutive patients submitted to ureterolithotomy following failure of endourological treatment.

Research paper thumbnail of Microdeletions of Y chromosome genes in infertile men

International Congress Series, 2004

Introduction: Male factor infertility accounts for about half the cases of couple infertility. De... more Introduction: Male factor infertility accounts for about half the cases of couple infertility. Deletions of the long arm of the Y chromosome are frequently associated with a failure of spermatogenesis. Objective: To evaluate the prevalence of Y microdeletions in infertile men. Methods: A total of 48 consecutive infertile men were evaluated to presence of Y chromosome microdeletion. Results: The microdeletion

Research paper thumbnail of Protective effect of allopurinol in the renal ischemia–reperfusion in uninephrectomized rats

General Pharmacology: The Vascular System, 2000

Research paper thumbnail of Persistence of Mullerian Duct Derivative Syndrome in 2 Male Patients with Bilateral Cryptorchidism

Journal of Urology, 1995

The persistent mullerian duct syndrome represents a rare form of male pseudohermaphroditism secon... more The persistent mullerian duct syndrome represents a rare form of male pseudohermaphroditism secondary to anti-mullerian hormone deficiency. We describe 2 cases of phenotypically male postpubertal patients with a uterus and tubes. Both patients presented with bilateral cryptorchidism, 1 was seen for gynecomastia and 1 was seen for an abdominal mass that was found to be a testicular tumor.

Research paper thumbnail of APPROPRIATE UTILIZATION OF QUALITY OF LIFE OUTCOMES IN PROSTATE AND BLADDER CANCER: PRACTICAL CONSIDERATIONS FOR BRAZILIAN PORTUGUESE QUESTIONNAIRES

Research paper thumbnail of DOES INTRATESTICULAR TESTOSTERONE ADMINISTRATION MODIFY THE EVOLUTION OF TRANSITORY TESTICULAR ISCHEMIA IN PREPUBERTAL RATS?

Journal of Urology, 1998

PurposeTesticular torsion followed by ischemia results in variable degrees of infertility and unt... more PurposeTesticular torsion followed by ischemia results in variable degrees of infertility and until now there appears to be no effective way to recover it. Testosterone participation in the maintenance of male sexual organs and spermatogenesis led us to hypothesize that intratesticular administration could recover ischemic injury.

Research paper thumbnail of Urethral catheter removal 7 or 14 days after radical retropubic prostatectomy: clinical implications and complications in a randomized study

Revista do Hospital das Clínicas, 2004

Research paper thumbnail of Is there any relation between serum levels of total testosterone and the severity of erectile dysfunction?

International Journal of Impotence Research, 2002

The objective of this study was to correlate the severity of erectile dysfunction (ED) with the t... more The objective of this study was to correlate the severity of erectile dysfunction (ED) with the total testosterone serum levels (TT) in a normal population. During a screening program for the early diagnosis of prostate cancer, 1071 men aged from 40 to 90 y, were invited to answer the questionnaire of the Simplified International Index of Erectile Function (IIEF-5) as

Research paper thumbnail of Intracavernosal etilefrine self-injection therapy for recurrent priapism: One decade of follow-up

Research paper thumbnail of MP-02.04

Research paper thumbnail of Salud y calidad de vida en urología: Aspectos en urología general y oncológica

Archivos Españoles de Urología (Ed. impresa), 2009

Research paper thumbnail of Multi-Institutional Validation of Vasectomy Reversal Predictor

The Journal of Urology, 2006

Research paper thumbnail of Plaque incision and grafting represents the best surgical approach to the Peyronie’s disease patient: Pro

Current Sexual Health Reports, 2006

Research paper thumbnail of 7006 Effect of baseline characteristics on prostate cancer rates and risk reduction in the Reduction by Dutasteride of prostate Cancer Events REDUCE) trial

European Journal of Cancer Supplements, 2009

Research paper thumbnail of ATROPINE ROLE IN THE PHARMACOLOGICAL ERECTION TEST: STUDY OF 228 PATIENTS

The Journal of Urology, 1997

We determined the efficacy of atropine sulfate combined with papaverine hydrochloride, prostaglan... more We determined the efficacy of atropine sulfate combined with papaverine hydrochloride, prostaglandin E1 and phentolamine mesylate in the pharmacological erection test. A total of 230 consecutive patients with erectile dysfunction was randomized for pharmacological erection test and received an intracorporeal combination of 50 mg. papaverine hydrochloride, 10 micrograms. prostaglandin E1, 0.2 mg. phentolamine mesylate and 0.075 mg. of atropine sulfate (group 1), or the same combination without atropine sulfate (group 2). Erectile response was evaluated subjectively and by intracorporeal pressure measurement. In group 1, 40 patients (35.1%) showed only tumescence, and 22 (19.3%) had poor erection. In group 2, 45 patients (39.5%) had tumescence and 17 (14.9%) poor erection. In both groups 52 patients (45.6%) had rigid erection. There was no statistically significant difference regarding erectile response and intracorporeal pressure. The addition of atropine sulfate did not improve results of the pharmacological erection test when combined with 50 mg. papverine hydrochloride, 10 micrograms, prostaglandin E1, and 0.2 mg. phentolamine mesylate.

Research paper thumbnail of Standards for Clinical Trials in Male Sexual Dysfunctions

Journal of Sexual Medicine, 2010

Research paper thumbnail of Magnetic Spheres as Foreign Body into the Bladder

The Journal of Sexual Medicine, 2012

Research paper thumbnail of Overactive bladder: prevalence and implications in Brazil

European urology, 2006

To assess overactive bladder (OAB) prevalence, associated factors and implications in a young pop... more To assess overactive bladder (OAB) prevalence, associated factors and implications in a young population. An independent population-based study was carried out. A self-applicative questionnaire covering urinary symptoms, coping strategies, quality of life and treatment seeking behavior was developed. A total of 848 subjects between 15 and 55 years completed the questionnaire. The overall prevalence of OAB was 18.9%. Women were significantly more affected than men (p = 0.001). All age groups were equally affected (p = 0.152). Subjects with OAB reported significant impairment on household chores (p = 0.009), physical activities (p = 0.016), sleep (p < 0.001), work (p < 0.001), social life (p < 0.001) and sexual life (p < 0.001). In addition, OAB individuals present higher prevalence of depression (p = 0.036), anxiety (p < 0.001), shame (p < 0.001) and tiredness (p < 0.001) OAB was independently associated to sexual life impairment (OR = 3.36, 95% CI=1.20-9.39). On...

Research paper thumbnail of Usefulness of prostate-specific antigen (PSA) rise as a marker of prostate cancer in men treated with dutasteride: lessons from the REDUCE study

BJU international, 2012

To determine if dutasteride-treated men can be monitored safely and adequately for prostate cance... more To determine if dutasteride-treated men can be monitored safely and adequately for prostate cancer based on data from the Reduction by Dutasteride in Prostate Cancer Events (REDUCE) study. To analyse whether the use of treatment-specific criteria for repeat biopsy maintains the usefulness of prostate-specific antigen (PSA) level for detecting high grade cancers. The REDUCE study was a randomized, double-blind, placebo-controlled investigation of whether dutasteride (0.5 mg/day) reduced the risk of biopsy-detectable prostate cancer in men with a previous negative biopsy. The usefulness of PSA was evaluated using biopsy thresholds defined by National Comprehensive Cancer Network guidelines in the placebo group and any rise in PSA from nadir (the lowest PSA level achieved while in the study) in the dutasteride group. The number of cancers detected on biopsy in the absence of increased/suspicious PSA level as well as sensitivity, specificity, positive predictive value and negative predi...

Research paper thumbnail of Oral Treatment of Peyronie’s Disease

Current Clinical Urology, 2007

This chapter reviews the possible effectiveness of oral agents as an option for treatment of Peyr... more This chapter reviews the possible effectiveness of oral agents as an option for treatment of Peyronie’s disease (PD). We present the rationale for use of these drugs and base our recommendations on levels of published evidence and the report by the International Consultation on Urological Diseases. A definitive and ideal medical therapy for PD has yet to be established and will not be until we completely understand the trigger mechanism and the maintenance process of fibrosis in the tunica albuginea. Several oral substances have been proposed with promises of success; however, these agents appear to lack robust scientific support for their benefit. Until new evidence is available, the indications for oral treatment in PD are recent onset of disease, painful plaque, and unstable plaque. An early trial of inexpensive, safe, and well-tolerated oral therapy may be offered with limited enthusiasm for a positive outcome.

Research paper thumbnail of Estudio prospectivo que compara laparoscopia y cirugía abierta para el tratamiento de cálculos ureterales impactados

Revue Neurologique, 2009

Introduction and objectivesTo investigate two ureterolithotomy approaches for treatment of large ... more Introduction and objectivesTo investigate two ureterolithotomy approaches for treatment of large and impacted upper ureteral stones, we prospectively evaluated the perioperative features of consecutive patients submitted to ureterolithotomy following failure of endourological treatment.

Research paper thumbnail of Microdeletions of Y chromosome genes in infertile men

International Congress Series, 2004

Introduction: Male factor infertility accounts for about half the cases of couple infertility. De... more Introduction: Male factor infertility accounts for about half the cases of couple infertility. Deletions of the long arm of the Y chromosome are frequently associated with a failure of spermatogenesis. Objective: To evaluate the prevalence of Y microdeletions in infertile men. Methods: A total of 48 consecutive infertile men were evaluated to presence of Y chromosome microdeletion. Results: The microdeletion

Research paper thumbnail of Protective effect of allopurinol in the renal ischemia–reperfusion in uninephrectomized rats

General Pharmacology: The Vascular System, 2000

Research paper thumbnail of Persistence of Mullerian Duct Derivative Syndrome in 2 Male Patients with Bilateral Cryptorchidism

Journal of Urology, 1995

The persistent mullerian duct syndrome represents a rare form of male pseudohermaphroditism secon... more The persistent mullerian duct syndrome represents a rare form of male pseudohermaphroditism secondary to anti-mullerian hormone deficiency. We describe 2 cases of phenotypically male postpubertal patients with a uterus and tubes. Both patients presented with bilateral cryptorchidism, 1 was seen for gynecomastia and 1 was seen for an abdominal mass that was found to be a testicular tumor.

Research paper thumbnail of APPROPRIATE UTILIZATION OF QUALITY OF LIFE OUTCOMES IN PROSTATE AND BLADDER CANCER: PRACTICAL CONSIDERATIONS FOR BRAZILIAN PORTUGUESE QUESTIONNAIRES

Research paper thumbnail of DOES INTRATESTICULAR TESTOSTERONE ADMINISTRATION MODIFY THE EVOLUTION OF TRANSITORY TESTICULAR ISCHEMIA IN PREPUBERTAL RATS?

Journal of Urology, 1998

PurposeTesticular torsion followed by ischemia results in variable degrees of infertility and unt... more PurposeTesticular torsion followed by ischemia results in variable degrees of infertility and until now there appears to be no effective way to recover it. Testosterone participation in the maintenance of male sexual organs and spermatogenesis led us to hypothesize that intratesticular administration could recover ischemic injury.

Research paper thumbnail of Urethral catheter removal 7 or 14 days after radical retropubic prostatectomy: clinical implications and complications in a randomized study

Revista do Hospital das Clínicas, 2004

Research paper thumbnail of Is there any relation between serum levels of total testosterone and the severity of erectile dysfunction?

International Journal of Impotence Research, 2002

The objective of this study was to correlate the severity of erectile dysfunction (ED) with the t... more The objective of this study was to correlate the severity of erectile dysfunction (ED) with the total testosterone serum levels (TT) in a normal population. During a screening program for the early diagnosis of prostate cancer, 1071 men aged from 40 to 90 y, were invited to answer the questionnaire of the Simplified International Index of Erectile Function (IIEF-5) as

Research paper thumbnail of Intracavernosal etilefrine self-injection therapy for recurrent priapism: One decade of follow-up

Research paper thumbnail of MP-02.04