Carla Valéria De Alvarenga Antunes | Universidade Federal de Juiz de Fora (original) (raw)

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Papers by Carla Valéria De Alvarenga Antunes

Research paper thumbnail of Tratamento da anemia por deficiência de ferro com ferro lipossomal oral em pacientes com doença inflamatória intestinal: eficácia, segurança e impactos nos escores psicométricos

Universidade Federal de Juiz de Fora (UFJF), 2019

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Research paper thumbnail of Quality of life in Anemic Patients with Inflammatory Bowel Disease

Brazilian Journal of Development

INTRODUCTION: Anemia is a common complication in inflammatory disease bowel (IBD). Many patients ... more INTRODUCTION: Anemia is a common complication in inflammatory disease bowel (IBD). Many patients have this comorbidity ignored during clinical follow-up. Nonetheless, studies of anemic patients have a significant relationship between anemia and low quality of life. This study evaluated the quality of life before and after treatment for anemia in mild anemic, IBD patients from the IBD Center of the UFJF University Hospital. OBJECTIVE: The objective of the present study was to investigate the improvement of quality of life after treatment of anemia in IBD patients. METHODS: In this cross-sectional study, 100 patients with CD (Crohn's disease) and 100 with RCUI (ulcerative colitis) were screened for anemia. For evaluation of anemia, complete blood count, ferritin, saturation index transferrin, serum levels of folic acid, serum iron and vitamin B12 was performed. In anemic patients, was evaluated and compared the levels of quality of life before and after anemia treatment. For the e...

Research paper thumbnail of Improvement of Anxiety, Depression and fatigue after treatment of Anemia in patients with inflammatory bowel disease patients

Brazilian Journal of Health Review

INTRODUCTION: Anemia is a common complication in inflammatory disease bowel (IBD). Many patients ... more INTRODUCTION: Anemia is a common complication in inflammatory disease bowel (IBD). Many patients have this comorbidity ignored during clinical follow-up. Nonetheless, studies of anemic patients have a significant relationship between anemia and higher anxiety, depression and fatigue. This study evaluated the level of anxiety, depression and fatigue before and after treatment for anemia in mild anemic, IBD patients from the IBD Center of the UFJF University Hospital. OBJECTIVE: The objective of the present study was to investigate the improvement of anxiety, depression and fatigue after treatment of anemia in IBD patients. METHODS: In this cross-sectional study, 100 patients with CD (Crohn's disease) and 100 with RCUI (ulcerative colitis) were screened for anemia. For evaluation of anemia, complete blood count, ferritin, saturation index transferrin, serum levels of folic acid, serum iron and vitamin B12 was performed. In anemic patients, was evaluated and compared the levels of ...

Research paper thumbnail of P019 Treatment of Iron Deficiency Anemia With Oral Liposomal Iron in IBD

The American Journal of Gastroenterology, 2019

Research paper thumbnail of Anemia in Inflammatory Bowel Disease Outpatients: Prevalence, Risk Factors, and Etiology

BioMed Research International, 2015

Anemia is common in inflammatory bowel disease (IBD). However, epidemiological studies of nonwest... more Anemia is common in inflammatory bowel disease (IBD). However, epidemiological studies of nonwestern IBD populations are limited and may be confounded by demographic, socioeconomic, and disease-related influences. This study evaluated the prevalence, risk factors, and etiology of anemia in Brazilian outpatients with IBD.Methods. In this cross-sectional study, 100 Crohn’s disease (CD) patients and 100 ulcerative colitis (UC) subjects were assessed. Anemia workup included complete blood count, ferritin, transferrin saturation, serum levels of folic acid and vitamin B12, and C-reactive protein (CRP) concentration.Results. The overall prevalence of anemia in IBD was 21%. There was no significant difference in the prevalence of anemia between CD subjects (24%) and UC (18%). Moderate disease activity (OR: 3.48, 95% CI, 1.95–9.64,P=0.002) and elevated CRP levels (OR: 1.8, 95% CI, 1.04–3.11,P=0.02) were independently associated with anemia. The most common etiologies of anemia found in both...

Research paper thumbnail of Anemia nas doenças inflamatórias intestinais: prevalência e fatores de risco

Anemia de dificil tratamento e uma manifestacao clinica comumente observada nos pacientes portado... more Anemia de dificil tratamento e uma manifestacao clinica comumente observada nos pacientes portadores de doencas inflamatorias intestinais, sendo responsavel por prejuizo significativo na qualidade de vida destes pacientes. O objetivo deste estudo foi avaliar, nos pacientes com doenca inflamatoria intestinal, a prevalencia e os fatores de risco da anemia suas possiveis etiologias. Neste estudo de corte prospectivo observacional foram recrutados: 100 pacientes portadores de Doenca de Crohn e 100 pacientes portadores de Retocolite ulcerativa, diagnosticados e acompanhados regularmente no Centro de Doencas Inflamatorias Intestinais do Hospital Universitario da Universidade Federal de Juiz de Fora, para avaliacao hematologica, bioquimica e imunologica. Foram obtidas amostras de sangue (20 ml) e realizados os seguintes exames em todos os pacientes: hemograma completo, VGM, HGM, CHGM, plaquetas, acido folico, vitamina B12, reticulocitos, indice de saturacao da transferrina, ferritina, ferr...

Research paper thumbnail of Treatment of iron deficiency anemia with liposomal iron in inflammatory bowel disease: efficacy and impact on quality of life

International Journal of Clinical Pharmacy

Research paper thumbnail of Anemia in Inflammatory Bowel Disease Outpatients: Prevalence, Risk Factors, and Etiology

BioMed Research International, 2015

Anemia is common in inflammatory bowel disease (IBD). However, epidemiological studies of nonwest... more Anemia is common in inflammatory bowel disease (IBD). However, epidemiological studies of nonwestern IBD populations are limited and may be confounded by demographic, socioeconomic, and disease-related influences. This study evaluated the prevalence, risk factors, and etiology of anemia in Brazilian outpatients with IBD. Methods. In this cross-sectional study, 100 Crohn's disease (CD) patients and 100 ulcerative colitis (UC) subjects were assessed. Anemia workup included complete blood count, ferritin, transferrin saturation, serum levels of folic acid and vitamin B12, and C-reactive protein (CRP) concentration. Results. The overall prevalence of anemia in IBD was 21%. There was no significant difference in the prevalence of anemia between CD subjects (24%) and UC (18%). Moderate disease activity (OR: 3.48, 95% CI, 1.95-9.64, P = 0.002) and elevated CRP levels (OR: 1.8, 95% CI, 1.04-3.11, P = 0.02) were independently associated with anemia. The most common etiologies of anemia found in both groups were iron deficiency anemia (IDA; 10% on CD and 6% on UC) followed by the anemia of chronic disease (ACD; 6% for both groups). Conclusions. In Brazilian IBD outpatients, anemia is highly concurrent condition. Disease moderate activity as well as increased CRP was strongly associated with comorbid anemia. IDA and/or ACD were the most common etiologies.

Research paper thumbnail of Tratamento da anemia por deficiência de ferro com ferro lipossomal oral em pacientes com doença inflamatória intestinal: eficácia, segurança e impactos nos escores psicométricos

Universidade Federal de Juiz de Fora (UFJF), 2019

-

Research paper thumbnail of Quality of life in Anemic Patients with Inflammatory Bowel Disease

Brazilian Journal of Development

INTRODUCTION: Anemia is a common complication in inflammatory disease bowel (IBD). Many patients ... more INTRODUCTION: Anemia is a common complication in inflammatory disease bowel (IBD). Many patients have this comorbidity ignored during clinical follow-up. Nonetheless, studies of anemic patients have a significant relationship between anemia and low quality of life. This study evaluated the quality of life before and after treatment for anemia in mild anemic, IBD patients from the IBD Center of the UFJF University Hospital. OBJECTIVE: The objective of the present study was to investigate the improvement of quality of life after treatment of anemia in IBD patients. METHODS: In this cross-sectional study, 100 patients with CD (Crohn's disease) and 100 with RCUI (ulcerative colitis) were screened for anemia. For evaluation of anemia, complete blood count, ferritin, saturation index transferrin, serum levels of folic acid, serum iron and vitamin B12 was performed. In anemic patients, was evaluated and compared the levels of quality of life before and after anemia treatment. For the e...

Research paper thumbnail of Improvement of Anxiety, Depression and fatigue after treatment of Anemia in patients with inflammatory bowel disease patients

Brazilian Journal of Health Review

INTRODUCTION: Anemia is a common complication in inflammatory disease bowel (IBD). Many patients ... more INTRODUCTION: Anemia is a common complication in inflammatory disease bowel (IBD). Many patients have this comorbidity ignored during clinical follow-up. Nonetheless, studies of anemic patients have a significant relationship between anemia and higher anxiety, depression and fatigue. This study evaluated the level of anxiety, depression and fatigue before and after treatment for anemia in mild anemic, IBD patients from the IBD Center of the UFJF University Hospital. OBJECTIVE: The objective of the present study was to investigate the improvement of anxiety, depression and fatigue after treatment of anemia in IBD patients. METHODS: In this cross-sectional study, 100 patients with CD (Crohn's disease) and 100 with RCUI (ulcerative colitis) were screened for anemia. For evaluation of anemia, complete blood count, ferritin, saturation index transferrin, serum levels of folic acid, serum iron and vitamin B12 was performed. In anemic patients, was evaluated and compared the levels of ...

Research paper thumbnail of P019 Treatment of Iron Deficiency Anemia With Oral Liposomal Iron in IBD

The American Journal of Gastroenterology, 2019

Research paper thumbnail of Anemia in Inflammatory Bowel Disease Outpatients: Prevalence, Risk Factors, and Etiology

BioMed Research International, 2015

Anemia is common in inflammatory bowel disease (IBD). However, epidemiological studies of nonwest... more Anemia is common in inflammatory bowel disease (IBD). However, epidemiological studies of nonwestern IBD populations are limited and may be confounded by demographic, socioeconomic, and disease-related influences. This study evaluated the prevalence, risk factors, and etiology of anemia in Brazilian outpatients with IBD.Methods. In this cross-sectional study, 100 Crohn’s disease (CD) patients and 100 ulcerative colitis (UC) subjects were assessed. Anemia workup included complete blood count, ferritin, transferrin saturation, serum levels of folic acid and vitamin B12, and C-reactive protein (CRP) concentration.Results. The overall prevalence of anemia in IBD was 21%. There was no significant difference in the prevalence of anemia between CD subjects (24%) and UC (18%). Moderate disease activity (OR: 3.48, 95% CI, 1.95–9.64,P=0.002) and elevated CRP levels (OR: 1.8, 95% CI, 1.04–3.11,P=0.02) were independently associated with anemia. The most common etiologies of anemia found in both...

Research paper thumbnail of Anemia nas doenças inflamatórias intestinais: prevalência e fatores de risco

Anemia de dificil tratamento e uma manifestacao clinica comumente observada nos pacientes portado... more Anemia de dificil tratamento e uma manifestacao clinica comumente observada nos pacientes portadores de doencas inflamatorias intestinais, sendo responsavel por prejuizo significativo na qualidade de vida destes pacientes. O objetivo deste estudo foi avaliar, nos pacientes com doenca inflamatoria intestinal, a prevalencia e os fatores de risco da anemia suas possiveis etiologias. Neste estudo de corte prospectivo observacional foram recrutados: 100 pacientes portadores de Doenca de Crohn e 100 pacientes portadores de Retocolite ulcerativa, diagnosticados e acompanhados regularmente no Centro de Doencas Inflamatorias Intestinais do Hospital Universitario da Universidade Federal de Juiz de Fora, para avaliacao hematologica, bioquimica e imunologica. Foram obtidas amostras de sangue (20 ml) e realizados os seguintes exames em todos os pacientes: hemograma completo, VGM, HGM, CHGM, plaquetas, acido folico, vitamina B12, reticulocitos, indice de saturacao da transferrina, ferritina, ferr...

Research paper thumbnail of Treatment of iron deficiency anemia with liposomal iron in inflammatory bowel disease: efficacy and impact on quality of life

International Journal of Clinical Pharmacy

Research paper thumbnail of Anemia in Inflammatory Bowel Disease Outpatients: Prevalence, Risk Factors, and Etiology

BioMed Research International, 2015

Anemia is common in inflammatory bowel disease (IBD). However, epidemiological studies of nonwest... more Anemia is common in inflammatory bowel disease (IBD). However, epidemiological studies of nonwestern IBD populations are limited and may be confounded by demographic, socioeconomic, and disease-related influences. This study evaluated the prevalence, risk factors, and etiology of anemia in Brazilian outpatients with IBD. Methods. In this cross-sectional study, 100 Crohn's disease (CD) patients and 100 ulcerative colitis (UC) subjects were assessed. Anemia workup included complete blood count, ferritin, transferrin saturation, serum levels of folic acid and vitamin B12, and C-reactive protein (CRP) concentration. Results. The overall prevalence of anemia in IBD was 21%. There was no significant difference in the prevalence of anemia between CD subjects (24%) and UC (18%). Moderate disease activity (OR: 3.48, 95% CI, 1.95-9.64, P = 0.002) and elevated CRP levels (OR: 1.8, 95% CI, 1.04-3.11, P = 0.02) were independently associated with anemia. The most common etiologies of anemia found in both groups were iron deficiency anemia (IDA; 10% on CD and 6% on UC) followed by the anemia of chronic disease (ACD; 6% for both groups). Conclusions. In Brazilian IBD outpatients, anemia is highly concurrent condition. Disease moderate activity as well as increased CRP was strongly associated with comorbid anemia. IDA and/or ACD were the most common etiologies.