Adail Orrith | Universidade Federal do Rio de Janeiro (UFRJ) (original) (raw)
Papers by Adail Orrith
Revista mexicana de pediatría, Jun 1, 2019
Revista Multidisciplinar em Saúde, Sep 1, 2020
Clinical & Biomedical Research, 2020
Rev. argent. dermatol, 2019
El eritema multiforme es un síndrome mucocutáneo habitualmente leve, caracterizado por un desorde... more El eritema multiforme es un síndrome mucocutáneo habitualmente leve, caracterizado por un desorden inflamatorio agudo inusual, que afecta la piel y / o las mucosas, con un grado de afectación variable, generalmente prevalece en adultos jóvenes aparentemente sanos y del sexo masculino. Se presenta con una variedad de lesiones, perola forma característica consiste en una mácula o pápula rojiza con un centro claro, a vecesvesicular,llamada lesión en diana. El eritema multiforme es una enfermedad rara, de fisiopatología aún no esclarecida, pero se cree que ocurre una reacción de hipersensibilidad inmunológica. Se describe un caso de eritema multiforme en un niño de 12 años,quien presentó lesiones en las mucosas y en la pielque requirió cuidados hospitalarios, medicado con:aciclovir, fluconazol y nistatina con favorable evolución. Erythema multiforme is a usually mild mucocutaneous syndrome, characterized by being an unusual acute inflammatory disorder that affects the skin and / or mucous membranes, with a variable degree of affectation, generally prevailing in apparently healthy young adults, and of the male sex. Patients manifest a variety of lesions, as well as a characteristic lesion form consisting of a reddish spot or papule with a clear,orvesicular centercalled a target lesion. Erythema multiforme is a rare disease, of physiopathology not yet clarified but it is believed that an immunological hypersensitivity reaction occurs. Thus, a case of erythema multiforme in a immunocompetent12-year-old boy with presentation of mucosal and skin lesions is described.
Clinical & Biomedical Research, 2021
Introduction: Gestational and congenital syphilis are diseases that can be prevented. Practices r... more Introduction: Gestational and congenital syphilis are diseases that can be prevented. Practices routinely carried out in prenatal care are effective for the prevention of cases. The prevalence of syphilis in pregnant women is considered an indicator of prenatal care quality. The objective is to define the epidemiological profile of pregnant women diagnosed with syphilis in the city of Macaé-Rio de Janeiro from 2010 to 2018. Methods: A cross-sectional retrospective study covering from 2010 to 2018 was conducted to assess the general prevalence in the period and annual incidence rates in records and database from the Care Center of Women and Children and from the Macaé Public Hospital. Results: A total of 535 cases of syphilis were reported in pregnant women. The highest number of reported cases was observed in 2018 (n = 151), with a detection rate of 38.4% per 1000 live births, meaning an increase of 37% compared to 2010. Most cases were diagnosed in the third trimester of pregnancy (n = 194 cases). The majority of women were aged 20-29 years (n = 322) and were housewives (n = 248). The predominant skin color was brown, accounting for 32.4% (n = 180) of the cases, followed by black skin (16.9%; n = 124). The majority of patients (n = 124) had incomplete elementary school education. The annual incidence rate of congenital syphilis increased from 1.4 to 17.2 cases per 1,000 live births between 2010 and 2018. Conclusions: There was an increased prevalence of syphilis in the city of Macaé, especially after 2015, with a peak of cases in 2018.
INTRODUCTION: Toxoplasmosis is a disease caused by the protozoan Toxoplasma gondii. The felines c... more INTRODUCTION: Toxoplasmosis is a disease caused by the protozoan Toxoplasma gondii. The felines correspond to the definitive host of this coccidia. The transmission can occur by eating raw or undercooked meat from infected animals or by eating water or poorly sanitized foods that are contaminated with oocysts. OBJECTIVES: To evaluate the risk factors for gestational toxoplasmosis in patients treated by the toxoplasmosis program in the city of Campos dos Goytacazes, RJ. METHODS: Documentary study (from 2013 to 2015). A total of 315 records of patients treated with a history of toxoplasmosis and referred to the Toxoplasmosis Program of Campos dos Goytacazes were evaluated at the Reference Center for Children and Adolescents. Data were tabulated in the EpiData® program and analyzed statistically by frequency of occurrence. DISCUSSION: The most frequent risk factor for toxoplasmosis is “neighbor has cats” (84.76%). Soares (2014) concluded that one of the risk factors for toxoplasmosis i...
GMS Ophthalmology Cases, 2021
Parinaud’s oculoglandular syndrome (POS) is a clinical condition characterized by granulomatous c... more Parinaud’s oculoglandular syndrome (POS) is a clinical condition characterized by granulomatous conjunctivitis associated with homolateral neck pain and anterior preauricular lymphadenopathy. Several reports of this condition occurred and some bacterial etiological agents were identified. However, fungal infections have also been associated, especially sporotrichosis. A 40-year-old female patient complained about a “little ball” in the lower eyelid of the left eye. On ocular examination, visual acuity and fundoscopy were normal. The biomicroscopy revealed a granulomatous lesion in the lower eyelid of the left eye associated with yellowish discharge. The patient returned the next day, reporting worsening of the condition accompanied by low fever, malaise, preauricular and submandibular lymphadenomegaly. The examination showed the evolution of conjunctival edema and various conjunctival granulomas in the lower and upper tarsus of the left eye, a clinical picture compatible with POS. I...
Ciências da Saúde: desafios, perspectivas e possibilidades - Volume 1, 2021
International Journal of Cardiovascular Sciences, 2021
Tetralogy of Fallot (TOF) consists of four cardiac changes: interventricular communication, pulmo... more Tetralogy of Fallot (TOF) consists of four cardiac changes: interventricular communication, pulmonary stenosis, aortic dextroposition and right ventricular hypertrophy. The prevalence is 0.1 per 1,000 live births. A primiparous mother with gestational age of 38 weeks came to the emergency. At the time, it was verified in her twin pregnancy that one fetus had TOF, thus a pregnancy interruption was scheduled for the following day. In the neonatal physical examination of both, localized acrocyanosis, regular heart rhythm with the presence of a heart murmur, and good peripheral perfusion were found. The echocardiogram of twin 1 revealed: patent foramen ovale; a wide perimembranous interventricular communication of misalignment, with the aorta riding the septum by 50%; hypertrophied and long infundibulum with pulmonary infundibulo-valvular stenosis, with a maximum systolic gradient of 66 mm Hg; both pulmonary arteries presented dimensions of 0.35 mm; pulmonary valve annulus: 0.56 mm; and patent ductus arteriosus measuring 0.19 mm. The echocardiogram of twin 2 showed: patent foramen ovale; a wide perimembranous interventricular communication of misalignment, with the aorta riding the septum by 50%; hypertrophied infundibulum with stenosis pulmonary infundibulo-valve, with a maximum systolic gradient of 33 mm Hg; reduced confluent pulmonary arteries; right pulmonary artery measuring 0.40 mm and left pulmonary artery measuring 0.55 mm; pulmonary valve annulus measuring 0.72 mm; a closed arterial canal, and mild aortic regurgitation. Tetralogy of Fallot is a multifaceted syndrome with a high prevalence in pediatrics. This case is the first case of congenital heart defect concordance for TOF in monozygotic twins in Brazil.
Clinical & Biomedical Research, 2021
Ebstein anomaly is the fourth most frequent cyanotic heart disease in the neonatal period, and it... more Ebstein anomaly is the fourth most frequent cyanotic heart disease in the neonatal period, and its clinical course is slow compared to other diseases, which in turn results in late diagnosis of this condition. We present a case of a 37-year-old man who complained of palpitation for about 5 years, twice a week, at rest, with prolonged duration and low systemic output. Auscultation revealed irregular heart rhythm characterized by extrasystoles with a tricuspid systolic murmur grade 5+/6 and worsening on inspiration. Clinical spectrum is variable and depends on the severity of defects and associated anatomical changes. In patients who have reached adulthood, symptoms usually present as progressive cyanosis, exercise intolerance, right heart failure, and arrhythmias. In Brazil, identification of this congenital disease usually occurs in a more adult phase, affecting the prognosis and survival of patients.
Jornal Brasileiro de Ginecologia, 2019
Introdução: A sífilis congênita (SC) é transmitida por via transplacentária para o feto em qualqu... more Introdução: A sífilis congênita (SC) é transmitida por via transplacentária para o feto em qualquer fase da gravidez. A taxa de transmissão vertical da sífilis é de 50 a 85% nas fases primária e secundária e de 30% nas fases latente e terciária. A SC pode produzir desfechos graves na gestação, como parto prematuro, óbito fetal e neonatal e infecção congênita do recém-nascido. Objetivo: Definir o perfil epidemiológico das gestantes com sífilis no município de Macaé-RJ, avaliando os fatores de risco para a transmissão da doença e verificando o tratamento das pacientes e de seus parceiros. Métodos: Estudo do tipo transversal retrospectivo entre os anos de 2010 a 2018, com consulta aos dados do Sistema de Informação de Agravos de Notificação (SINAN) e pesquisa documental em prontuários e banco de dados de unidades públicas de saúde do município. Resultados: Observou-se maior incidência em gestantes de 15 a 39 anos, faixa etária de população sexualmente ativa. Em outro corte, verificou-s...
Revista Científica Multidisciplinar Núcleo do Conhecimento, 2020
The Jarisch-Herxheimer reaction is a feverish inflammatory reaction witch may occur after the tre... more The Jarisch-Herxheimer reaction is a feverish inflammatory reaction witch may occur after the treatment of patients for syphilis at all stages. Commonly begin between in the first 12 hours after treatment. In pregnant women the reaction may end up in prematurity and fetal death, especially when the fetus is infected. It’s necessary to be aware of all the patient’s complaints and take a look at to group them in a single medical diagnosis whenever possible. And it’s principal that obstetricians always have Jarisch-Herxheimer reaction as a medical diagnosis for febrile syndromes in pregnant women with syphilis.
Scientia Medica, 2018
A case of congenital toxoplasmosis with microcephaly occurred during the epidemic by Zika virus i... more A case of congenital toxoplasmosis with microcephaly occurred during the epidemic by Zika virus in Brazil, and only being diagnosed as toxoplasmosis at seven months of age, is described. This case illustrates the pertinence and urgency for the implementation of specific public policies for prevention, diagnosis and treatment for toxoplasmosis acquired during pregnancy, and shows that when the subject is microcephaly due to congenital infections in Brazil, one must be attentive to other possibilities besides Zika virus infection; in particular to congenital toxoplasmosis, which is highly prevalent in our country, and if diagnosed and treated in due course, irreversible neurological and ocular damage may be avoided. We fully support the Ministry of Health ordinance that makes it compulsory to notify cases of gestational and congenital toxoplasmosis in the country. The actions that will be implemented should result in a specific national program for gestational and congenital toxoplasm...
Blucher Medical Proceedings, 2019
Revista Científica Multidisciplinar Núcleo do Conhecimento, 2017
Some of the authors of this publication are also working on these related projects: Nível de estr... more Some of the authors of this publication are also working on these related projects: Nível de estresse percebido e qualidade do sono entre os funcionários públicos da cidade universitária View project Influência do consumo da linhaça (linum usitatissimum) durante a gestação e lactaçao sobre a morfologia renal da prole adulta oriunda de ratas wistar com diabetes mellitus tipo II View project
Conjunctival and bulbar sporotrichosis as Parinaud’s oculoglandular syndrome acquired by blood inoculation, Jan 28, 2021
Parinaud’s oculoglandular syndrome (POS) is a clinical condition characterized by granulomatous c... more Parinaud’s oculoglandular syndrome (POS) is a clinical condition characterized by granulomatous conjunctivitis associated with homolateral neck pain and anterior preauricular lymphadenopathy. Several reports of this condition occurred and some bacterial etiological agents were identified. However, fungal infections have also been associated, especially sporotrichosis. A 40-year-old female patient complained about a “little ball” in the lower eyelid of the left eye. On ocular examination, visual acuity and fundoscopy were normal. The biomicroscopy revealed a granulomatous lesion in the lower eyelid of the left eye associated with yellowish discharge. The patient returned the next day, reporting worsening of the condition accompanied by low fever, malaise, pre-auricular and submandibular lymphadenomegaly. The examination showed the evolution of conjunctival edema and various conjunctival granulomas in the lower and upper tarsus of the left eye, a clinical picture compatible with POS. In the investigation of the clinical history, the patient remembered an episode of contact with blood of cats. During the investigation, we discarded differential diagnoses such as tuberculosis, toxoplasmosis, CMV, herpes virus and Bartonella. Serology was positive for Sporothrix. Treatment with itraconazole 100 mg once daily was started. By the eighth week, the conjunctival granulomas had disappeared, and the medication was discontinued after 90 days of treatment, after about 2 weeks of total remission. According to the literature, there are no cases of primarily ocular manifestation of blood sporotrichosis transmission. However, in the report, the form of transmission of the disease occurred by inoculation by direct contact with the blood of contaminated cats.
Revista Científica Multidisciplinar Núcleo do Conhecimento, 2020
The Jarisch-Herxheimer reaction is a feverish inflammatory reaction witch may occur after the tre... more The Jarisch-Herxheimer reaction is a feverish inflammatory reaction witch may occur after the treatment of patients for syphilis at all stages. Commonly begin between in the first 12 hours after treatment. In pregnant women the reaction may end up in prematurity and fetal death, especially when the fetus is infected. It’s necessary to be aware of all the patient’s complaints and take a look at to group them in a single medical diagnosis whenever possible. And it’s principal that obstetricians always have Jarisch-Herxheimer reaction as a medical diagnosis for febrile syndromes in pregnant women with syphilis.
Diversidade Celular e Suas Localizações. Revista Científica Multidisciplinar Núcleo do Conhecimento, 2017
RESUMO O sistema nervoso é contundido basicamente por um dos quatro tipos básicos de tecidos do c... more RESUMO O sistema nervoso é contundido basicamente por um dos quatro tipos básicos de tecidos do corpo, o tecido nervoso, encontrando-se distribuído por todo organismo. É formado por neurônios e as células glia ou neuróglia, os quais possuem origem no ectoderma. Entretanto, o sistema nervoso também é composto por células modificadas do tecido conjuntivo e epitelial. Todas estas células agrupam-se, formando o Sistema Nervoso, que é dividido em Sistema Nervoso Central (encéfalo e medula espinhal, protegido pelas meninges) e em Sistema Nervoso Periférico (gânglios nervosos e nervos). Essa revisão bibliográfica tem o objetivo de explanar as características morfológicas, diferentes tipos celulares e localizações das células e estruturas que constituem o sistema nervoso demonstrando, assim, a extensão, diversidade, flexibilidade e significância das células desse sistema e suas interações com os outros sistemas que constituem o corpo humano. Palavras-chave: Nervoso, Glia, Neurônios, Neuroglia, Medula, Gânglio, Nervo, Meninges, Histologia. 1. INTRODUÇÃO O tecido nervoso é distribuído pelo organismo, interligando-se e formando uma rede de comunicações, que constitui o sistema nervoso. Anatomicamente, este sistema é dividido em: sistema nervoso central (SNC), formado pelo encéfalo, constituintes neurais do sistema fotorreceptor e medula espinal, e sistema nervoso periférico (SNP), formado pelos nervos e por agregados de células nervosas denominados gânglios. Os nervos são constituídos principalmente por prolongamentos dos neurônios situados no SNC ou nos gânglios nervosos. O tecido nervoso apresenta dois componentes principais: os neurônios, células geralmente com longos prolongamentos, e vários tipos de células da glia ou neuróglia, que sustentam os neurônios e participam de outras funções importantes. (JUNQUEIRA; CARNEIRO, 2013) 2. MATERIAIS E MÉTODOS Foi feita a análise dos principais livros de Histologia e neuroanatomia disponíveis no Brasil: JUNQUEIRA; CARNEIRO, Histologia Básica, 12ª Ed.; GARTNER; HIATT, Tratado de Histologia em Cores, 2ª Ed.; KIERSZENBAUM, B. L. Histologia e biologia celular: uma introdução à patologia. 3º Ed.; Machado, ABM. Neuroanatomia funcional, 3°Ed.; MONTANARI, Histologia-Texto, Atlas e Roteiro de Aulas Práticas-Série Graduação-2 Ed.; Gray's Anatomia-29 Ed. Como também de artigos na área de histologia consultados na base de dados Scielo e Google Acadêmico.
FATORES DE RISCO PARA A TOXOPLASMOSE GESTACIONAL EM CAMPOS DOS GOYTACAZES RJ, 2016
INTRODUÇÃO: A toxoplasmose é uma doença causada pelo protozoário Toxoplasma gondii. Os felinos co... more INTRODUÇÃO: A toxoplasmose é uma doença causada
pelo protozoário Toxoplasma gondii. Os felinos
correspondem ao hospedeiro definitivo deste coccídio. Sua
transmissão pode ocorrer pela ingestão de carne crua ou
mal cozida de animais infectados ou pelo consumo de água
e alimentos mal higienizados que estejam contaminados com
oocistos. OBJETIVOS: Avaliar os fatores de risco para a
toxoplasmose gestacional entre pacientes atendidas pelo
programa de toxoplasmose do município de Campos dos
Goytacazes, RJ. MÉTODOS: Estudo Documental (de 2013
a 2015). Foram avaliados 315 prontuários de pacientes
atendidas com história de toxoplasmose e referenciadas para
o Programa de Toxoplasmose de Campos dos Goytacazes,
no Centro de Referência da Criança e do Adolescente. Os
dados foram tabulados no programa EpiData® e analisados
estatisticamente por frequência de ocorrência.
DISCUSSÃO: O fator de risco com maior ocorrência para
toxoplasmose é “vizinho ter gatos” (84,76%). Soares (2014)
concluiu que um dos fatores de risco para a toxoplasmose é
ter animais domésticos e Carneiro (2003) considerou os
gatos importante variável na infecção por Toxoplasma
gondii. CONCLUSÃO: O fator de risco com maior
prevalência foi “vizinho ter gatos”. O de risco com menor
frequência foi “ter ouvido casos de toxoplasmose entre os
vizinhos”. Concluímos que a informação acerca desta
doença que chega aos que vivem em áreas de risco é
deficitária. Desse modo, a educação da população sobre a
toxoplasmose e suas vias de transmissão é imprescindível
para reduzir a prevalência e os gastos públicos com a protozoose.
Revista mexicana de pediatría, Jun 1, 2019
Revista Multidisciplinar em Saúde, Sep 1, 2020
Clinical & Biomedical Research, 2020
Rev. argent. dermatol, 2019
El eritema multiforme es un síndrome mucocutáneo habitualmente leve, caracterizado por un desorde... more El eritema multiforme es un síndrome mucocutáneo habitualmente leve, caracterizado por un desorden inflamatorio agudo inusual, que afecta la piel y / o las mucosas, con un grado de afectación variable, generalmente prevalece en adultos jóvenes aparentemente sanos y del sexo masculino. Se presenta con una variedad de lesiones, perola forma característica consiste en una mácula o pápula rojiza con un centro claro, a vecesvesicular,llamada lesión en diana. El eritema multiforme es una enfermedad rara, de fisiopatología aún no esclarecida, pero se cree que ocurre una reacción de hipersensibilidad inmunológica. Se describe un caso de eritema multiforme en un niño de 12 años,quien presentó lesiones en las mucosas y en la pielque requirió cuidados hospitalarios, medicado con:aciclovir, fluconazol y nistatina con favorable evolución. Erythema multiforme is a usually mild mucocutaneous syndrome, characterized by being an unusual acute inflammatory disorder that affects the skin and / or mucous membranes, with a variable degree of affectation, generally prevailing in apparently healthy young adults, and of the male sex. Patients manifest a variety of lesions, as well as a characteristic lesion form consisting of a reddish spot or papule with a clear,orvesicular centercalled a target lesion. Erythema multiforme is a rare disease, of physiopathology not yet clarified but it is believed that an immunological hypersensitivity reaction occurs. Thus, a case of erythema multiforme in a immunocompetent12-year-old boy with presentation of mucosal and skin lesions is described.
Clinical & Biomedical Research, 2021
Introduction: Gestational and congenital syphilis are diseases that can be prevented. Practices r... more Introduction: Gestational and congenital syphilis are diseases that can be prevented. Practices routinely carried out in prenatal care are effective for the prevention of cases. The prevalence of syphilis in pregnant women is considered an indicator of prenatal care quality. The objective is to define the epidemiological profile of pregnant women diagnosed with syphilis in the city of Macaé-Rio de Janeiro from 2010 to 2018. Methods: A cross-sectional retrospective study covering from 2010 to 2018 was conducted to assess the general prevalence in the period and annual incidence rates in records and database from the Care Center of Women and Children and from the Macaé Public Hospital. Results: A total of 535 cases of syphilis were reported in pregnant women. The highest number of reported cases was observed in 2018 (n = 151), with a detection rate of 38.4% per 1000 live births, meaning an increase of 37% compared to 2010. Most cases were diagnosed in the third trimester of pregnancy (n = 194 cases). The majority of women were aged 20-29 years (n = 322) and were housewives (n = 248). The predominant skin color was brown, accounting for 32.4% (n = 180) of the cases, followed by black skin (16.9%; n = 124). The majority of patients (n = 124) had incomplete elementary school education. The annual incidence rate of congenital syphilis increased from 1.4 to 17.2 cases per 1,000 live births between 2010 and 2018. Conclusions: There was an increased prevalence of syphilis in the city of Macaé, especially after 2015, with a peak of cases in 2018.
INTRODUCTION: Toxoplasmosis is a disease caused by the protozoan Toxoplasma gondii. The felines c... more INTRODUCTION: Toxoplasmosis is a disease caused by the protozoan Toxoplasma gondii. The felines correspond to the definitive host of this coccidia. The transmission can occur by eating raw or undercooked meat from infected animals or by eating water or poorly sanitized foods that are contaminated with oocysts. OBJECTIVES: To evaluate the risk factors for gestational toxoplasmosis in patients treated by the toxoplasmosis program in the city of Campos dos Goytacazes, RJ. METHODS: Documentary study (from 2013 to 2015). A total of 315 records of patients treated with a history of toxoplasmosis and referred to the Toxoplasmosis Program of Campos dos Goytacazes were evaluated at the Reference Center for Children and Adolescents. Data were tabulated in the EpiData® program and analyzed statistically by frequency of occurrence. DISCUSSION: The most frequent risk factor for toxoplasmosis is “neighbor has cats” (84.76%). Soares (2014) concluded that one of the risk factors for toxoplasmosis i...
GMS Ophthalmology Cases, 2021
Parinaud’s oculoglandular syndrome (POS) is a clinical condition characterized by granulomatous c... more Parinaud’s oculoglandular syndrome (POS) is a clinical condition characterized by granulomatous conjunctivitis associated with homolateral neck pain and anterior preauricular lymphadenopathy. Several reports of this condition occurred and some bacterial etiological agents were identified. However, fungal infections have also been associated, especially sporotrichosis. A 40-year-old female patient complained about a “little ball” in the lower eyelid of the left eye. On ocular examination, visual acuity and fundoscopy were normal. The biomicroscopy revealed a granulomatous lesion in the lower eyelid of the left eye associated with yellowish discharge. The patient returned the next day, reporting worsening of the condition accompanied by low fever, malaise, preauricular and submandibular lymphadenomegaly. The examination showed the evolution of conjunctival edema and various conjunctival granulomas in the lower and upper tarsus of the left eye, a clinical picture compatible with POS. I...
Ciências da Saúde: desafios, perspectivas e possibilidades - Volume 1, 2021
International Journal of Cardiovascular Sciences, 2021
Tetralogy of Fallot (TOF) consists of four cardiac changes: interventricular communication, pulmo... more Tetralogy of Fallot (TOF) consists of four cardiac changes: interventricular communication, pulmonary stenosis, aortic dextroposition and right ventricular hypertrophy. The prevalence is 0.1 per 1,000 live births. A primiparous mother with gestational age of 38 weeks came to the emergency. At the time, it was verified in her twin pregnancy that one fetus had TOF, thus a pregnancy interruption was scheduled for the following day. In the neonatal physical examination of both, localized acrocyanosis, regular heart rhythm with the presence of a heart murmur, and good peripheral perfusion were found. The echocardiogram of twin 1 revealed: patent foramen ovale; a wide perimembranous interventricular communication of misalignment, with the aorta riding the septum by 50%; hypertrophied and long infundibulum with pulmonary infundibulo-valvular stenosis, with a maximum systolic gradient of 66 mm Hg; both pulmonary arteries presented dimensions of 0.35 mm; pulmonary valve annulus: 0.56 mm; and patent ductus arteriosus measuring 0.19 mm. The echocardiogram of twin 2 showed: patent foramen ovale; a wide perimembranous interventricular communication of misalignment, with the aorta riding the septum by 50%; hypertrophied infundibulum with stenosis pulmonary infundibulo-valve, with a maximum systolic gradient of 33 mm Hg; reduced confluent pulmonary arteries; right pulmonary artery measuring 0.40 mm and left pulmonary artery measuring 0.55 mm; pulmonary valve annulus measuring 0.72 mm; a closed arterial canal, and mild aortic regurgitation. Tetralogy of Fallot is a multifaceted syndrome with a high prevalence in pediatrics. This case is the first case of congenital heart defect concordance for TOF in monozygotic twins in Brazil.
Clinical & Biomedical Research, 2021
Ebstein anomaly is the fourth most frequent cyanotic heart disease in the neonatal period, and it... more Ebstein anomaly is the fourth most frequent cyanotic heart disease in the neonatal period, and its clinical course is slow compared to other diseases, which in turn results in late diagnosis of this condition. We present a case of a 37-year-old man who complained of palpitation for about 5 years, twice a week, at rest, with prolonged duration and low systemic output. Auscultation revealed irregular heart rhythm characterized by extrasystoles with a tricuspid systolic murmur grade 5+/6 and worsening on inspiration. Clinical spectrum is variable and depends on the severity of defects and associated anatomical changes. In patients who have reached adulthood, symptoms usually present as progressive cyanosis, exercise intolerance, right heart failure, and arrhythmias. In Brazil, identification of this congenital disease usually occurs in a more adult phase, affecting the prognosis and survival of patients.
Jornal Brasileiro de Ginecologia, 2019
Introdução: A sífilis congênita (SC) é transmitida por via transplacentária para o feto em qualqu... more Introdução: A sífilis congênita (SC) é transmitida por via transplacentária para o feto em qualquer fase da gravidez. A taxa de transmissão vertical da sífilis é de 50 a 85% nas fases primária e secundária e de 30% nas fases latente e terciária. A SC pode produzir desfechos graves na gestação, como parto prematuro, óbito fetal e neonatal e infecção congênita do recém-nascido. Objetivo: Definir o perfil epidemiológico das gestantes com sífilis no município de Macaé-RJ, avaliando os fatores de risco para a transmissão da doença e verificando o tratamento das pacientes e de seus parceiros. Métodos: Estudo do tipo transversal retrospectivo entre os anos de 2010 a 2018, com consulta aos dados do Sistema de Informação de Agravos de Notificação (SINAN) e pesquisa documental em prontuários e banco de dados de unidades públicas de saúde do município. Resultados: Observou-se maior incidência em gestantes de 15 a 39 anos, faixa etária de população sexualmente ativa. Em outro corte, verificou-s...
Revista Científica Multidisciplinar Núcleo do Conhecimento, 2020
The Jarisch-Herxheimer reaction is a feverish inflammatory reaction witch may occur after the tre... more The Jarisch-Herxheimer reaction is a feverish inflammatory reaction witch may occur after the treatment of patients for syphilis at all stages. Commonly begin between in the first 12 hours after treatment. In pregnant women the reaction may end up in prematurity and fetal death, especially when the fetus is infected. It’s necessary to be aware of all the patient’s complaints and take a look at to group them in a single medical diagnosis whenever possible. And it’s principal that obstetricians always have Jarisch-Herxheimer reaction as a medical diagnosis for febrile syndromes in pregnant women with syphilis.
Scientia Medica, 2018
A case of congenital toxoplasmosis with microcephaly occurred during the epidemic by Zika virus i... more A case of congenital toxoplasmosis with microcephaly occurred during the epidemic by Zika virus in Brazil, and only being diagnosed as toxoplasmosis at seven months of age, is described. This case illustrates the pertinence and urgency for the implementation of specific public policies for prevention, diagnosis and treatment for toxoplasmosis acquired during pregnancy, and shows that when the subject is microcephaly due to congenital infections in Brazil, one must be attentive to other possibilities besides Zika virus infection; in particular to congenital toxoplasmosis, which is highly prevalent in our country, and if diagnosed and treated in due course, irreversible neurological and ocular damage may be avoided. We fully support the Ministry of Health ordinance that makes it compulsory to notify cases of gestational and congenital toxoplasmosis in the country. The actions that will be implemented should result in a specific national program for gestational and congenital toxoplasm...
Blucher Medical Proceedings, 2019
Revista Científica Multidisciplinar Núcleo do Conhecimento, 2017
Some of the authors of this publication are also working on these related projects: Nível de estr... more Some of the authors of this publication are also working on these related projects: Nível de estresse percebido e qualidade do sono entre os funcionários públicos da cidade universitária View project Influência do consumo da linhaça (linum usitatissimum) durante a gestação e lactaçao sobre a morfologia renal da prole adulta oriunda de ratas wistar com diabetes mellitus tipo II View project
Conjunctival and bulbar sporotrichosis as Parinaud’s oculoglandular syndrome acquired by blood inoculation, Jan 28, 2021
Parinaud’s oculoglandular syndrome (POS) is a clinical condition characterized by granulomatous c... more Parinaud’s oculoglandular syndrome (POS) is a clinical condition characterized by granulomatous conjunctivitis associated with homolateral neck pain and anterior preauricular lymphadenopathy. Several reports of this condition occurred and some bacterial etiological agents were identified. However, fungal infections have also been associated, especially sporotrichosis. A 40-year-old female patient complained about a “little ball” in the lower eyelid of the left eye. On ocular examination, visual acuity and fundoscopy were normal. The biomicroscopy revealed a granulomatous lesion in the lower eyelid of the left eye associated with yellowish discharge. The patient returned the next day, reporting worsening of the condition accompanied by low fever, malaise, pre-auricular and submandibular lymphadenomegaly. The examination showed the evolution of conjunctival edema and various conjunctival granulomas in the lower and upper tarsus of the left eye, a clinical picture compatible with POS. In the investigation of the clinical history, the patient remembered an episode of contact with blood of cats. During the investigation, we discarded differential diagnoses such as tuberculosis, toxoplasmosis, CMV, herpes virus and Bartonella. Serology was positive for Sporothrix. Treatment with itraconazole 100 mg once daily was started. By the eighth week, the conjunctival granulomas had disappeared, and the medication was discontinued after 90 days of treatment, after about 2 weeks of total remission. According to the literature, there are no cases of primarily ocular manifestation of blood sporotrichosis transmission. However, in the report, the form of transmission of the disease occurred by inoculation by direct contact with the blood of contaminated cats.
Revista Científica Multidisciplinar Núcleo do Conhecimento, 2020
The Jarisch-Herxheimer reaction is a feverish inflammatory reaction witch may occur after the tre... more The Jarisch-Herxheimer reaction is a feverish inflammatory reaction witch may occur after the treatment of patients for syphilis at all stages. Commonly begin between in the first 12 hours after treatment. In pregnant women the reaction may end up in prematurity and fetal death, especially when the fetus is infected. It’s necessary to be aware of all the patient’s complaints and take a look at to group them in a single medical diagnosis whenever possible. And it’s principal that obstetricians always have Jarisch-Herxheimer reaction as a medical diagnosis for febrile syndromes in pregnant women with syphilis.
Diversidade Celular e Suas Localizações. Revista Científica Multidisciplinar Núcleo do Conhecimento, 2017
RESUMO O sistema nervoso é contundido basicamente por um dos quatro tipos básicos de tecidos do c... more RESUMO O sistema nervoso é contundido basicamente por um dos quatro tipos básicos de tecidos do corpo, o tecido nervoso, encontrando-se distribuído por todo organismo. É formado por neurônios e as células glia ou neuróglia, os quais possuem origem no ectoderma. Entretanto, o sistema nervoso também é composto por células modificadas do tecido conjuntivo e epitelial. Todas estas células agrupam-se, formando o Sistema Nervoso, que é dividido em Sistema Nervoso Central (encéfalo e medula espinhal, protegido pelas meninges) e em Sistema Nervoso Periférico (gânglios nervosos e nervos). Essa revisão bibliográfica tem o objetivo de explanar as características morfológicas, diferentes tipos celulares e localizações das células e estruturas que constituem o sistema nervoso demonstrando, assim, a extensão, diversidade, flexibilidade e significância das células desse sistema e suas interações com os outros sistemas que constituem o corpo humano. Palavras-chave: Nervoso, Glia, Neurônios, Neuroglia, Medula, Gânglio, Nervo, Meninges, Histologia. 1. INTRODUÇÃO O tecido nervoso é distribuído pelo organismo, interligando-se e formando uma rede de comunicações, que constitui o sistema nervoso. Anatomicamente, este sistema é dividido em: sistema nervoso central (SNC), formado pelo encéfalo, constituintes neurais do sistema fotorreceptor e medula espinal, e sistema nervoso periférico (SNP), formado pelos nervos e por agregados de células nervosas denominados gânglios. Os nervos são constituídos principalmente por prolongamentos dos neurônios situados no SNC ou nos gânglios nervosos. O tecido nervoso apresenta dois componentes principais: os neurônios, células geralmente com longos prolongamentos, e vários tipos de células da glia ou neuróglia, que sustentam os neurônios e participam de outras funções importantes. (JUNQUEIRA; CARNEIRO, 2013) 2. MATERIAIS E MÉTODOS Foi feita a análise dos principais livros de Histologia e neuroanatomia disponíveis no Brasil: JUNQUEIRA; CARNEIRO, Histologia Básica, 12ª Ed.; GARTNER; HIATT, Tratado de Histologia em Cores, 2ª Ed.; KIERSZENBAUM, B. L. Histologia e biologia celular: uma introdução à patologia. 3º Ed.; Machado, ABM. Neuroanatomia funcional, 3°Ed.; MONTANARI, Histologia-Texto, Atlas e Roteiro de Aulas Práticas-Série Graduação-2 Ed.; Gray's Anatomia-29 Ed. Como também de artigos na área de histologia consultados na base de dados Scielo e Google Acadêmico.
FATORES DE RISCO PARA A TOXOPLASMOSE GESTACIONAL EM CAMPOS DOS GOYTACAZES RJ, 2016
INTRODUÇÃO: A toxoplasmose é uma doença causada pelo protozoário Toxoplasma gondii. Os felinos co... more INTRODUÇÃO: A toxoplasmose é uma doença causada
pelo protozoário Toxoplasma gondii. Os felinos
correspondem ao hospedeiro definitivo deste coccídio. Sua
transmissão pode ocorrer pela ingestão de carne crua ou
mal cozida de animais infectados ou pelo consumo de água
e alimentos mal higienizados que estejam contaminados com
oocistos. OBJETIVOS: Avaliar os fatores de risco para a
toxoplasmose gestacional entre pacientes atendidas pelo
programa de toxoplasmose do município de Campos dos
Goytacazes, RJ. MÉTODOS: Estudo Documental (de 2013
a 2015). Foram avaliados 315 prontuários de pacientes
atendidas com história de toxoplasmose e referenciadas para
o Programa de Toxoplasmose de Campos dos Goytacazes,
no Centro de Referência da Criança e do Adolescente. Os
dados foram tabulados no programa EpiData® e analisados
estatisticamente por frequência de ocorrência.
DISCUSSÃO: O fator de risco com maior ocorrência para
toxoplasmose é “vizinho ter gatos” (84,76%). Soares (2014)
concluiu que um dos fatores de risco para a toxoplasmose é
ter animais domésticos e Carneiro (2003) considerou os
gatos importante variável na infecção por Toxoplasma
gondii. CONCLUSÃO: O fator de risco com maior
prevalência foi “vizinho ter gatos”. O de risco com menor
frequência foi “ter ouvido casos de toxoplasmose entre os
vizinhos”. Concluímos que a informação acerca desta
doença que chega aos que vivem em áreas de risco é
deficitária. Desse modo, a educação da população sobre a
toxoplasmose e suas vias de transmissão é imprescindível
para reduzir a prevalência e os gastos públicos com a protozoose.