Robert G Burton - The University of Georgia (original) (raw)
Papers by Robert G Burton
On the central limit theorem for dynamical system
A Disaggregate Analysis of University Patent and Licensing Behavior
Measurement of biological activity of ambient air mixtures using a mobile laboratory for in situ exposures: preliminary results from the Tradescantia plant test system
A variety of short-term bioassays has been developed to assess the mutagenicity of industrial che... more A variety of short-term bioassays has been developed to assess the mutagenicity of industrial chemicals. Many of these assays work well when used under laboratory conditions but are not suitable for monitoring ambient air under field conditions. To facilitate exposures of biological systems to ambient air pollution in natural or industrial sites a plan was implemented to design, assemble and
Development and validation of a fourfold multiplexed opsonization assay (MOPA4) for pneumococcal antibodies
Clinical and vaccine immunology : CVI, 2006
Opsonophagocytic killing assays (OPAs) are essential for developing and improving pneumococcal va... more Opsonophagocytic killing assays (OPAs) are essential for developing and improving pneumococcal vaccines. There is a need for a high-throughput, reliable, standardized, and fully characterized OPA for pneumococcal antibodies. To meet the need, we have developed and characterized a fourfold multiplexed OPA (MOPA4) against 13 serotypes (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, and 23F) of pneumococci. Thirteen target bacteria were made resistant to only one of the following antibiotics: optochin, streptomycin, spectinomycin, and trimethoprim. Following optimization of assay conditions, accuracy of MOPA4 was determined by testing 30 sera from old adults in the MOPA4 and the single-serotype assays. The opsonization titers obtained with both assays agreed well (r(2) > 0.95). Although 22 (out of 390; approximately 6%) results differed more than twofold, the differences were not reproducible. The assay was specific: preabsorbing test sera with homologous polysaccharide (PS) complet...
Heidrun - Results from Pre-Completed Techniques ells Using Innovative Gravelpacking
Offshore Technology Conference, 1996
Finite state bilaterally deterministic strongly mixing processes
Atmospheric effects on friction and wear of oxidized copper
Wear, 1965
Impaired serotype-specific immune function following pneumococcal vaccination in infants with prior carriage
Vaccine, 2014
The impact of prior nasopharyngeal carriage on serotype-specific IgG responses following immuniza... more The impact of prior nasopharyngeal carriage on serotype-specific IgG responses following immunization with pneumococcal conjugate vaccines (PCV) has recently been described. This report extends these findings to describe the attenuation of functional immune responses following 23-valent pneumococcal polysaccharide vaccination (PPS). We report the attenuation of immune responses following booster with the 23-valent pneumococcal polysaccharide vaccination (PPS) in infants with prior nasopharyngeal carriage of Streptococcus pneumoniae. Fijian infants who were part of a phase II randomized, controlled trial of reduced dose PCV7 schedules were the basis of this study. Pneumococcal carriage was determined at 6, 9 and 12 months of age, prior to PPS immunization. Serum samples collected at 18 weeks (post-PCV7), 12 months (pre-PPS), 12.5 months and 17 months (post-PPS) of age were assessed for serotype-specific IgG and opsonophagocytic responses. The most frequently carried serotypes were 6B (N=11), 19F (N=14) and 23F (N=23). Significantly lower serotype-specific IgG for 19F, 23F but not 6B post-PPS were detected in infants with homologous serotype carriage prior to PPS compared with non-carriers (N=230). However, OPA levels for 6B and 23F were lower in infants that carried these serotypes. Pneumococcal carriage with 19F or 23F at any time prior to PPS immunization in infants at 12 months of age who were previously primed with PCV resulted in serotype-specific hyporesponsiveness that persisted until 17 months of age. These results may have implications for the timing of infant vaccine schedules, particularly in high disease burden settings.
Sand Control Completion Design, Installation and Performance of High Rate Gas Wells in the Jupiter Field
SPE Formation Damage Control Conference, 1998
... Particulate invasion of the pore throats was not indicated as a primary damage mechanism. The... more ... Particulate invasion of the pore throats was not indicated as a primary damage mechanism. The conventional water based mud containing 35 ppb KCL and 110ppb dolomite provided ... The use of polymeric fluid loss control additives resulted in impaired return permeability. ...
International Journal of Osteopathic Medicine, 2003
The application of electro-thermal coupling simulation and high impedance dynamic loadline probin... more The application of electro-thermal coupling simulation and high impedance dynamic loadline probing to the understanding and optimization of a GSM power amplifier (PA) is described. Electro-thermal simulation explains the temperature imbalance across the output HBT PA stage, which may lead to thermal collapse and amplifier damage. Direct probing of the voltage and current waveforms at different locations on the output
Surface displacements for high speed rubs
Wear, 1980
The T-REX valley wind intercomparison project
An accurate simulation of the evolution of the atmospheric boundary layer is very important, as t... more An accurate simulation of the evolution of the atmospheric boundary layer is very important, as the evolution of the boundary layer sets the stage for many weather phenomena, such as deep convection. Over mountain areas the evolution of the boundary layer is particularly complex, due to the nonlinear interaction between boundary layer turbulence and thermally-induced mesoscale wind systems, such as
THE SHORE WHALING STATIONS AT SOUTH GEORGIA: A STUDY IN ANTARCTIC INDUSTRIAL ARCHAEOLOGY . Bjørn Basberg. 2004. Oslo: Novus forlag. 226 p, illustrated, hard cover. ISBN 82-7099-394-8. NOK298; EUR36.30
Polar Record, 2005
ATP-dependent protein degradation and unfolding by ClpXP
GBM Annual Fall meeting Halle 2002, 2002
The Pediatric infectious disease journal, 2010
The heptavalent pneumococcal CRM197 conjugate vaccine (PCV-7) has been incompletely studied in ve... more The heptavalent pneumococcal CRM197 conjugate vaccine (PCV-7) has been incompletely studied in very-low-birth-weight (< or =1500 g) infants. To assess PCV-7 immunogenicity in very-low-birth-weight, premature infants. We hypothesized that the frequency of postvaccine antibody concentrations > or =0.15 microg/mL would vary directly with birth weight. This was a multicenter observational study. Infants 401 to 1500 g birth weight and <32 0/7 weeks gestation, stratified by birth weight, were enrolled from 9 National Institute of Child Health and Human Development Neonatal Research Network centers. Infants received PCV-7 at 2, 4, and 6 months after birth and had blood drawn 4 to 6 weeks following the third dose. Antibodies against the 7 vaccine serotypes were measured by enzyme-linked immunosorbent assay. Of 369 enrolled infants, 244 completed their primary vaccine series by 8 months and had serum obtained. Subjects were 27.8 +/- 2.2 (mean +/- standard deviation) weeks gestation ...
| 7. Understanding the Value of Biodiversity in Water Ecosystems: Economics, Ethics and Social Psychology
The empirical work involved an extension of the standard CVM to include social psychological driv... more The empirical work involved an extension of the standard CVM to include social psychological drivers and to test their power in explaining willingness to pay (WTP). Investigating the motives that drive responses to CVM surveys was a key concern because of the range of problems which have been encountered in CVM surveys in the past. Specific attention was given to
The variational principle for Gibbs states fails on trees
Markov Process. Related Fields, 1995
We show how the variational principle for Gibbs States (which says that for the d {dimensional cu... more We show how the variational principle for Gibbs States (which says that for the d {dimensional cubic lattice, the set of translation invariant Gibbs States is the same as the set of translation invariant measures which maximize entropy minus energy and moreover ...
A model-driven question-answer-incy system for mixed-initiative computer-assisted instruction
Sanitary sewer rehabilitation at Lawrence Livermore National Laboratory
The objectives of this paper are the following: to present LLNL`s collection system and innovativ... more The objectives of this paper are the following: to present LLNL`s collection system and innovative approach to sanitary sewer rehabilitation; share issues identified and lessons learned from over four (4) years of rehabilitation work; and discuss proposed system standards for ongoing maintenance and repair activities.
Thermoelastic instability of sliding contact in the absence of wear
Wear, 1972
On the central limit theorem for dynamical system
A Disaggregate Analysis of University Patent and Licensing Behavior
Measurement of biological activity of ambient air mixtures using a mobile laboratory for in situ exposures: preliminary results from the Tradescantia plant test system
A variety of short-term bioassays has been developed to assess the mutagenicity of industrial che... more A variety of short-term bioassays has been developed to assess the mutagenicity of industrial chemicals. Many of these assays work well when used under laboratory conditions but are not suitable for monitoring ambient air under field conditions. To facilitate exposures of biological systems to ambient air pollution in natural or industrial sites a plan was implemented to design, assemble and
Development and validation of a fourfold multiplexed opsonization assay (MOPA4) for pneumococcal antibodies
Clinical and vaccine immunology : CVI, 2006
Opsonophagocytic killing assays (OPAs) are essential for developing and improving pneumococcal va... more Opsonophagocytic killing assays (OPAs) are essential for developing and improving pneumococcal vaccines. There is a need for a high-throughput, reliable, standardized, and fully characterized OPA for pneumococcal antibodies. To meet the need, we have developed and characterized a fourfold multiplexed OPA (MOPA4) against 13 serotypes (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, and 23F) of pneumococci. Thirteen target bacteria were made resistant to only one of the following antibiotics: optochin, streptomycin, spectinomycin, and trimethoprim. Following optimization of assay conditions, accuracy of MOPA4 was determined by testing 30 sera from old adults in the MOPA4 and the single-serotype assays. The opsonization titers obtained with both assays agreed well (r(2) > 0.95). Although 22 (out of 390; approximately 6%) results differed more than twofold, the differences were not reproducible. The assay was specific: preabsorbing test sera with homologous polysaccharide (PS) complet...
Heidrun - Results from Pre-Completed Techniques ells Using Innovative Gravelpacking
Offshore Technology Conference, 1996
Finite state bilaterally deterministic strongly mixing processes
Atmospheric effects on friction and wear of oxidized copper
Wear, 1965
Impaired serotype-specific immune function following pneumococcal vaccination in infants with prior carriage
Vaccine, 2014
The impact of prior nasopharyngeal carriage on serotype-specific IgG responses following immuniza... more The impact of prior nasopharyngeal carriage on serotype-specific IgG responses following immunization with pneumococcal conjugate vaccines (PCV) has recently been described. This report extends these findings to describe the attenuation of functional immune responses following 23-valent pneumococcal polysaccharide vaccination (PPS). We report the attenuation of immune responses following booster with the 23-valent pneumococcal polysaccharide vaccination (PPS) in infants with prior nasopharyngeal carriage of Streptococcus pneumoniae. Fijian infants who were part of a phase II randomized, controlled trial of reduced dose PCV7 schedules were the basis of this study. Pneumococcal carriage was determined at 6, 9 and 12 months of age, prior to PPS immunization. Serum samples collected at 18 weeks (post-PCV7), 12 months (pre-PPS), 12.5 months and 17 months (post-PPS) of age were assessed for serotype-specific IgG and opsonophagocytic responses. The most frequently carried serotypes were 6B (N=11), 19F (N=14) and 23F (N=23). Significantly lower serotype-specific IgG for 19F, 23F but not 6B post-PPS were detected in infants with homologous serotype carriage prior to PPS compared with non-carriers (N=230). However, OPA levels for 6B and 23F were lower in infants that carried these serotypes. Pneumococcal carriage with 19F or 23F at any time prior to PPS immunization in infants at 12 months of age who were previously primed with PCV resulted in serotype-specific hyporesponsiveness that persisted until 17 months of age. These results may have implications for the timing of infant vaccine schedules, particularly in high disease burden settings.
Sand Control Completion Design, Installation and Performance of High Rate Gas Wells in the Jupiter Field
SPE Formation Damage Control Conference, 1998
... Particulate invasion of the pore throats was not indicated as a primary damage mechanism. The... more ... Particulate invasion of the pore throats was not indicated as a primary damage mechanism. The conventional water based mud containing 35 ppb KCL and 110ppb dolomite provided ... The use of polymeric fluid loss control additives resulted in impaired return permeability. ...
International Journal of Osteopathic Medicine, 2003
The application of electro-thermal coupling simulation and high impedance dynamic loadline probin... more The application of electro-thermal coupling simulation and high impedance dynamic loadline probing to the understanding and optimization of a GSM power amplifier (PA) is described. Electro-thermal simulation explains the temperature imbalance across the output HBT PA stage, which may lead to thermal collapse and amplifier damage. Direct probing of the voltage and current waveforms at different locations on the output
Surface displacements for high speed rubs
Wear, 1980
The T-REX valley wind intercomparison project
An accurate simulation of the evolution of the atmospheric boundary layer is very important, as t... more An accurate simulation of the evolution of the atmospheric boundary layer is very important, as the evolution of the boundary layer sets the stage for many weather phenomena, such as deep convection. Over mountain areas the evolution of the boundary layer is particularly complex, due to the nonlinear interaction between boundary layer turbulence and thermally-induced mesoscale wind systems, such as
THE SHORE WHALING STATIONS AT SOUTH GEORGIA: A STUDY IN ANTARCTIC INDUSTRIAL ARCHAEOLOGY . Bjørn Basberg. 2004. Oslo: Novus forlag. 226 p, illustrated, hard cover. ISBN 82-7099-394-8. NOK298; EUR36.30
Polar Record, 2005
ATP-dependent protein degradation and unfolding by ClpXP
GBM Annual Fall meeting Halle 2002, 2002
The Pediatric infectious disease journal, 2010
The heptavalent pneumococcal CRM197 conjugate vaccine (PCV-7) has been incompletely studied in ve... more The heptavalent pneumococcal CRM197 conjugate vaccine (PCV-7) has been incompletely studied in very-low-birth-weight (< or =1500 g) infants. To assess PCV-7 immunogenicity in very-low-birth-weight, premature infants. We hypothesized that the frequency of postvaccine antibody concentrations > or =0.15 microg/mL would vary directly with birth weight. This was a multicenter observational study. Infants 401 to 1500 g birth weight and <32 0/7 weeks gestation, stratified by birth weight, were enrolled from 9 National Institute of Child Health and Human Development Neonatal Research Network centers. Infants received PCV-7 at 2, 4, and 6 months after birth and had blood drawn 4 to 6 weeks following the third dose. Antibodies against the 7 vaccine serotypes were measured by enzyme-linked immunosorbent assay. Of 369 enrolled infants, 244 completed their primary vaccine series by 8 months and had serum obtained. Subjects were 27.8 +/- 2.2 (mean +/- standard deviation) weeks gestation ...
| 7. Understanding the Value of Biodiversity in Water Ecosystems: Economics, Ethics and Social Psychology
The empirical work involved an extension of the standard CVM to include social psychological driv... more The empirical work involved an extension of the standard CVM to include social psychological drivers and to test their power in explaining willingness to pay (WTP). Investigating the motives that drive responses to CVM surveys was a key concern because of the range of problems which have been encountered in CVM surveys in the past. Specific attention was given to
The variational principle for Gibbs states fails on trees
Markov Process. Related Fields, 1995
We show how the variational principle for Gibbs States (which says that for the d {dimensional cu... more We show how the variational principle for Gibbs States (which says that for the d {dimensional cubic lattice, the set of translation invariant Gibbs States is the same as the set of translation invariant measures which maximize entropy minus energy and moreover ...
A model-driven question-answer-incy system for mixed-initiative computer-assisted instruction
Sanitary sewer rehabilitation at Lawrence Livermore National Laboratory
The objectives of this paper are the following: to present LLNL`s collection system and innovativ... more The objectives of this paper are the following: to present LLNL`s collection system and innovative approach to sanitary sewer rehabilitation; share issues identified and lessons learned from over four (4) years of rehabilitation work; and discuss proposed system standards for ongoing maintenance and repair activities.
Thermoelastic instability of sliding contact in the absence of wear
Wear, 1972