Van Pham | Ghent University (original) (raw)

Van Pham

Address: Dung, Thanh Hoa, Vietnam

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Papers by Van Pham

Research paper thumbnail of An insight into the sialome of the adult female mosquito Aedes albopictus

Insect Biochemistry and Molecular Biology, 2007

Research paper thumbnail of Exploring the salivary gland transcriptome and proteome of the Anopheles stephensi mosquito

Insect Biochemistry and Molecular Biology, 2003

Research paper thumbnail of From transcriptome to immunome: Identification of DTH inducing proteins from a Phlebotomus ariasi salivary gland cDNA library

Research paper thumbnail of A Role for Insect Galectins in Parasite Survival

Cell, 2004

Insect galectins are associated with embryonic development or immunity against pathogens. Here, w... more Insect galectins are associated with embryonic development or immunity against pathogens. Here, we show that they can be exploited by parasites for survival in their insect hosts. PpGalec, a tandem repeat galectin expressed in the midgut of the sand fly Phlebotomus papatasi, is used by Leishmania major as a receptor for mediating specific binding to the insect midgut, an event crucial for parasite survival, and accounts for species-specific vector competence. PpGalec is thus identified as a key molecule controlling vector competence for the most widely distributed form of cutaneous leishmaniasis in the Old World. In addition, these studies demonstrate the feasibility of using midgut receptors for parasite ligands as target antigens for transmission-blocking vaccines.

Research paper thumbnail of Identification of the most abundant secreted proteins from the salivary glands of the sand fly Lutzomyia longipalpis, vector of Leishmania chagasi

Journal of Experimental Biology, 2004

Research paper thumbnail of The transcriptome of the salivary glands of the female western black-legged tick Ixodes pacificus (Acari: Ixodidae

Insect Biochemistry and Molecular Biology, 2005

Research paper thumbnail of An insight into the salivary transcriptome and proteome of the adult female mosquito Culex pipiens quinquefasciatus

Insect Biochemistry and Molecular Biology, 2004

Research paper thumbnail of Comparative sialomics between hard and soft ticks: Implications for the evolution of blood-feeding behavior

Insect Biochemistry and Molecular Biology, 2008

Research paper thumbnail of The effect of low-k ILD on the electromigration reliability of Cu interconnects with different line lengths

We have compared the electromigration performance of Cu electromigration structures with varying ... more We have compared the electromigration performance of Cu electromigration structures with varying line lengths imbedded in two different ILD materials. In the regime of high jL where there is no significant back-stress, we observed that three of the key electromigration parameters (i.e., MTF, n, and σ) are constant and approximately equivalent between the two materials. In the regime of lower jL where there is significant back-stress, both materials exhibit similar trends, however, the Cu with low-k material performed relatively worse in terms of MTF and similarly in terms of n and σ. That is, while the MTF of Cu with both materials increased with decreasing jL, the MTF of Cu with low-k material was less than that of the Cu with SiO2-based material due to lower back-stress at a given jL. Further, while a regime of complete immortality was observed for the SiO2-based material, no regime of immortality was observed for the low-k material. The values of n and σ were comparable for both materials, and were constant in the absence of significant back-stress but increased in the presence of significant back-stress. Due to the higher MTFs in the regime of high backstress, MTF is more sensitive to j and L, thereby increasing n as per Black's Law. The increase in σ is a consequence of heightened sensitivity to process variations such as via barrier integrity and CD variation.

Research paper thumbnail of An insight into the sialome of the adult female mosquito Aedes albopictus

Insect Biochemistry and Molecular Biology, 2007

Research paper thumbnail of Exploring the salivary gland transcriptome and proteome of the Anopheles stephensi mosquito

Insect Biochemistry and Molecular Biology, 2003

Research paper thumbnail of From transcriptome to immunome: Identification of DTH inducing proteins from a Phlebotomus ariasi salivary gland cDNA library

Research paper thumbnail of A Role for Insect Galectins in Parasite Survival

Cell, 2004

Insect galectins are associated with embryonic development or immunity against pathogens. Here, w... more Insect galectins are associated with embryonic development or immunity against pathogens. Here, we show that they can be exploited by parasites for survival in their insect hosts. PpGalec, a tandem repeat galectin expressed in the midgut of the sand fly Phlebotomus papatasi, is used by Leishmania major as a receptor for mediating specific binding to the insect midgut, an event crucial for parasite survival, and accounts for species-specific vector competence. PpGalec is thus identified as a key molecule controlling vector competence for the most widely distributed form of cutaneous leishmaniasis in the Old World. In addition, these studies demonstrate the feasibility of using midgut receptors for parasite ligands as target antigens for transmission-blocking vaccines.

Research paper thumbnail of Identification of the most abundant secreted proteins from the salivary glands of the sand fly Lutzomyia longipalpis, vector of Leishmania chagasi

Journal of Experimental Biology, 2004

Research paper thumbnail of The transcriptome of the salivary glands of the female western black-legged tick Ixodes pacificus (Acari: Ixodidae

Insect Biochemistry and Molecular Biology, 2005

Research paper thumbnail of An insight into the salivary transcriptome and proteome of the adult female mosquito Culex pipiens quinquefasciatus

Insect Biochemistry and Molecular Biology, 2004

Research paper thumbnail of Comparative sialomics between hard and soft ticks: Implications for the evolution of blood-feeding behavior

Insect Biochemistry and Molecular Biology, 2008

Research paper thumbnail of The effect of low-k ILD on the electromigration reliability of Cu interconnects with different line lengths

We have compared the electromigration performance of Cu electromigration structures with varying ... more We have compared the electromigration performance of Cu electromigration structures with varying line lengths imbedded in two different ILD materials. In the regime of high jL where there is no significant back-stress, we observed that three of the key electromigration parameters (i.e., MTF, n, and σ) are constant and approximately equivalent between the two materials. In the regime of lower jL where there is significant back-stress, both materials exhibit similar trends, however, the Cu with low-k material performed relatively worse in terms of MTF and similarly in terms of n and σ. That is, while the MTF of Cu with both materials increased with decreasing jL, the MTF of Cu with low-k material was less than that of the Cu with SiO2-based material due to lower back-stress at a given jL. Further, while a regime of complete immortality was observed for the SiO2-based material, no regime of immortality was observed for the low-k material. The values of n and σ were comparable for both materials, and were constant in the absence of significant back-stress but increased in the presence of significant back-stress. Due to the higher MTFs in the regime of high backstress, MTF is more sensitive to j and L, thereby increasing n as per Black's Law. The increase in σ is a consequence of heightened sensitivity to process variations such as via barrier integrity and CD variation.

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