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Research paper thumbnail of Using Risk to Balance Agile and Plan-Driven Methods

Computer, Jan 1, 2003

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Research paper thumbnail of Risk factors in enterprise-wide/ERP projects

Journal of Information Technology, Jan 1, 2001

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Research paper thumbnail of Estimation of contribution of changes in classic risk factors to trends in coronary-event rates across the WHO MONICA Project populations

The Lancet, Jan 1, 2000

From the mid-1980s to mid-1990s, the WHO MONICA Project monitored coronary events and classic ris... more From the mid-1980s to mid-1990s, the WHO MONICA Project monitored coronary events and classic risk factors for coronary heart disease (CHD) in 38 populations from 21 countries. We assessed the extent to which changes in these risk factors explain the variation in the trends in coronary-event rates across the populations. In men and women aged 35-64 years, non-fatal myocardial infarction and coronary deaths were registered continuously to assess trends in rates of coronary events. We carried out population surveys to estimate trends in risk factors. Trends in event rates were regressed on trends in risk score and in individual risk factors. Smoking rates decreased in most male populations but trends were mixed in women; mean blood pressures and cholesterol concentrations decreased, bodymass index increased, and overall risk scores and coronary-event rates decreased. The model of trends in 10-year coronary-event rates against risk scores and single risk factors showed a poor fit, but this was improved with a 4-year time lag for coronary events. The explanatory power of the analyses was limited by imprecision of the estimates and homogeneity of trends in the study populations. Changes in the classic risk factors seem to partly explain the variation in population trends in CHD. Residual variance is attributable to difficulties in measurement and analysis, including time lag, and to factors that were not included, such as medical interventions. The results support prevention policies based on the classic risk factors but suggest potential for prevention beyond these.

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Research paper thumbnail of Risk factors and outcome in European cardiac surgery: analysis of the EuroSCORE multinational database of 19030 patients

European journal of …, Jan 1, 1999

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Research paper thumbnail of …  Calcium Independently Predicts Incident Premature Coronary Heart Disease Over Measured Cardiovascular Risk Factors:: Mean Three-Year Outcomes in the  …

Journal of the American …, Jan 1, 2005

Coronary calcium was found in 22.4% of men and 7.9% of women. A total of 9 acute events occurred ... more Coronary calcium was found in 22.4% of men and 7.9% of women. A total of 9 acute events occurred in men at a mean age of 46 years, including 7 of 364 men with coronary calcium (1.95%) and 2 of 1,263 men without coronary calcium (0.16%; p < 0.0001 by log-rank). No events ...

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Research paper thumbnail of International project risk assessment: methods, procedures, and critical factors

… Industry Studies, University of Texas at …, Jan 1, 2003

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Research paper thumbnail of Using Risk to Balance Agile and Plan-Driven Methods

Computer, Jan 1, 2003

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Research paper thumbnail of Risk factors in enterprise-wide/ERP projects

Journal of Information Technology, Jan 1, 2001

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Estimation of contribution of changes in classic risk factors to trends in coronary-event rates across the WHO MONICA Project populations

The Lancet, Jan 1, 2000

From the mid-1980s to mid-1990s, the WHO MONICA Project monitored coronary events and classic ris... more From the mid-1980s to mid-1990s, the WHO MONICA Project monitored coronary events and classic risk factors for coronary heart disease (CHD) in 38 populations from 21 countries. We assessed the extent to which changes in these risk factors explain the variation in the trends in coronary-event rates across the populations. In men and women aged 35-64 years, non-fatal myocardial infarction and coronary deaths were registered continuously to assess trends in rates of coronary events. We carried out population surveys to estimate trends in risk factors. Trends in event rates were regressed on trends in risk score and in individual risk factors. Smoking rates decreased in most male populations but trends were mixed in women; mean blood pressures and cholesterol concentrations decreased, bodymass index increased, and overall risk scores and coronary-event rates decreased. The model of trends in 10-year coronary-event rates against risk scores and single risk factors showed a poor fit, but this was improved with a 4-year time lag for coronary events. The explanatory power of the analyses was limited by imprecision of the estimates and homogeneity of trends in the study populations. Changes in the classic risk factors seem to partly explain the variation in population trends in CHD. Residual variance is attributable to difficulties in measurement and analysis, including time lag, and to factors that were not included, such as medical interventions. The results support prevention policies based on the classic risk factors but suggest potential for prevention beyond these.

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Risk factors and outcome in European cardiac surgery: analysis of the EuroSCORE multinational database of 19030 patients

European journal of …, Jan 1, 1999

Bookmarks Related papers MentionsView impact

Research paper thumbnail of …  Calcium Independently Predicts Incident Premature Coronary Heart Disease Over Measured Cardiovascular Risk Factors:: Mean Three-Year Outcomes in the  …

Journal of the American …, Jan 1, 2005

Coronary calcium was found in 22.4% of men and 7.9% of women. A total of 9 acute events occurred ... more Coronary calcium was found in 22.4% of men and 7.9% of women. A total of 9 acute events occurred in men at a mean age of 46 years, including 7 of 364 men with coronary calcium (1.95%) and 2 of 1,263 men without coronary calcium (0.16%; p < 0.0001 by log-rank). No events ...

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Research paper thumbnail of International project risk assessment: methods, procedures, and critical factors

… Industry Studies, University of Texas at …, Jan 1, 2003

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