Tseganesh Asefa | University of Gondar (original) (raw)

Uploads

Papers by Tseganesh Asefa

Research paper thumbnail of Incidence and predictors of recurrent acute coronary syndrome among adult patients with acute coronary syndrome in West Amhara, Ethiopia: a multicenter retrospective follow-up study

Frontiers in Cardiovascular Medicine, Oct 15, 2023

Research paper thumbnail of Sleep Quality and Associated Factors Among Adult Cancer Patients Under Treatment at Oncology Units in Amhara Region, Ethiopia

Nature and Science of Sleep, Jun 1, 2022

Poor sleep quality, a common, under-diagnosed, and under-treated problem in cancer patients, has ... more Poor sleep quality, a common, under-diagnosed, and under-treated problem in cancer patients, has negative physical and psychological consequences, but its prevalence and associated factors are not well studied in Ethiopia. Thus, the present study aimed to assess the prevalence of sleep quality and its associated factors among adult cancer patients receiving treatment at oncology units in Amhara region, Ethiopia. Methods and Materials: An institution-based cross-sectional study was conducted among adult patients with cancer under treatment at the oncology units in the Amhara region from April 12 to May 12/2021. A systematic random sampling technique was used to select 423 samples. Data were collected using a structured Interviewer-administered questionnaire. Sleep quality and depression were assessed by the Pittsburgh Sleep Quality Index and depression subscale of Hospital Anxiety and Depression Scale, respectively. Bivariable and multivariable logistic regression analyses were computed, considering p < 0.25 to select candidate variables for multivariable analysis and p < 0.05 to be statistically significant in the final model. Results: A total of 410 cancer patients participated in this study. The mean of the participant's age was 44.2 (range: 20-77) years. More than half (52.7%) of participants received chemotherapy and the remaining were treated with a combination of treatments. Twohundred ninety-three (71.5%) of participants had poor sleep quality and 28.5% had good sleep quality. The factors found to be significantly associated with poor sleep quality were advanced age [AOR = 1.037, 95%

Research paper thumbnail of Knowledge, attitude and practice of breast self examination among female undergraduate nursing students at university of gondar, college of medicine and health sciences

Hospice & palliative medicine international journal, Nov 5, 2019

Introduction: BSE is simple, non-invasive, requires little time and cost free practice and it can... more Introduction: BSE is simple, non-invasive, requires little time and cost free practice and it can be perform by both young and old women. By performing BSE can recognize changes, such as thickening, lumps, spontaneous nipple discharge or skin change, and dimpling. However, the women who not perform BSE are high risk for breast cancer. Breast cancer is the second most frequent occurring cancer among women. Objective: The object of this study to assess the knowledge, attitude and practice of BSE among female undergraduate CMHS, university of Gondar student`s. Methods: An institution based cross sectional study design was conducted at the University of Gondar, collage of medicine and health science from April to June 2018. A total of 300 students were included in this study. The source population was all female undergraduate nursing students. The study was selected by simple random sampling technique. Selfadministered questionnaire was used for data collection. Then data was entered to Epi info version 3.5.4. The enter data was export to SPSS statistical package for analysis. Result: In this study, a total of 300 undergraduate female nursing students participated in the study and giving a response rate of 100% About knowledge of the female undergraduate students with regard to BSE is found to be 55.7% with 95% CI: (56-61%) had knowledge of breast self examination while 176 (56.7%) with 95% CI: (53-64%) of the female undergraduate students have favorable attitude about BSE. Of the total participants, 34 (11.3%) with 95% CI: (7-15%) of the female undergraduate students had practiced Conclusion: In general, the KAP of the participants were, 55.7% with 95% CI: (56-61%), 56.7% with 95% CI: (53-64%) and 11.3% with 95% CI: (7-15%) respectively. This finding showed that the participants had poor KAP toward BSE. Therefore, Universities and other stake holders should plan to promote provision of information, education and communication targeting females, and the general community to increase awareness to ward breast self examination.

Research paper thumbnail of Postpartum depression and associated factor among mothers attending public health centers of Yeka sub city, addis ababa Ethiopia

Research paper thumbnail of Sleep Quality and Associated Factors Among Adult Cancer Patients Under Treatment at Oncology Units in Amhara Region, Ethiopia

Nature and Science of Sleep

Poor sleep quality, a common, under-diagnosed, and under-treated problem in cancer patients, has ... more Poor sleep quality, a common, under-diagnosed, and under-treated problem in cancer patients, has negative physical and psychological consequences, but its prevalence and associated factors are not well studied in Ethiopia. Thus, the present study aimed to assess the prevalence of sleep quality and its associated factors among adult cancer patients receiving treatment at oncology units in Amhara region, Ethiopia. Methods and Materials: An institution-based cross-sectional study was conducted among adult patients with cancer under treatment at the oncology units in the Amhara region from April 12 to May 12/2021. A systematic random sampling technique was used to select 423 samples. Data were collected using a structured Interviewer-administered questionnaire. Sleep quality and depression were assessed by the Pittsburgh Sleep Quality Index and depression subscale of Hospital Anxiety and Depression Scale, respectively. Bivariable and multivariable logistic regression analyses were computed, considering p < 0.25 to select candidate variables for multivariable analysis and p < 0.05 to be statistically significant in the final model. Results: A total of 410 cancer patients participated in this study. The mean of the participant's age was 44.2 (range: 20-77) years. More than half (52.7%) of participants received chemotherapy and the remaining were treated with a combination of treatments. Twohundred ninety-three (71.5%) of participants had poor sleep quality and 28.5% had good sleep quality. The factors found to be significantly associated with poor sleep quality were advanced age [AOR = 1.037, 95%

Research paper thumbnail of The Impact of Impaired Swallowing Related Quality of Life of Head and Neck Cancer Survivors at Tikur Anbessa Specialized Referral Hospital, Addis Ababa, Ethiopia: 2019 G.C (Mixed Method Study)

Introduction: Different research and international clinical guidelines deals about the importance... more Introduction: Different research and international clinical guidelines deals about the importance of addressing and supporting the Quality of Life needs of individuals with impaired swallowing. However, data support that the presence of swallowing impairment related Quality of Life has not directly addressed in the reviewed studies in Ethiopia. Objective: This study was conducted to assess factors that affect swallowing related quality of life and it is impacts in head and neck cancer survivors. Methods: To achieve the objective of this study 102 patients were enrolled in cross sectional study, of whom 7 were purposively selected for in depth interviews of qualitative study. The study was conducted from March to April 2019 G.C at the oncology center of Tikur Anbessa Specialized Referral Hospital, Addis Ababa, Ethiopia. The pre coded data was entered in to EpiData version 4.4.3.1 then exported to Statistical Package for the Social Sciences version 24 for further cleaning, and analysi...

Research paper thumbnail of Determinants of Mortality among Cervical Cancer Patients Attending in Tikur Anbessa Specialized Hospital, Ethiopia: Institutional-Based Retrospective Study

Background Globally, about 570,000 cases and 311,000 deaths of cervical cancer occurred in 2018. ... more Background Globally, about 570,000 cases and 311,000 deaths of cervical cancer occurred in 2018. It was the leading cause of cancer-related deaths among women in Africa. The global mean age at death of cervical cancer was about 59 years. This study aimed to assess the determinants of cervical cancer mortality among cervical cancer patients attending in Tikur Anbessa Specialized Hospital (TASH). Methods Institutional-based retrospective cohort study was conducted in the oncology center of TASH, Ethiopia, from March to April 2019. Data were extracted from patients' chart using structured checklist and analyzed using Stata 14.2. Cox regression was used to identify variables that affect the outcome variable. Result From the total of 2045 reviewed medical records of cervical cancer patients, 1057 medical records were found to be complete and included in this study. The incidence of mortality among cervical cancer patients was 15.6/100/years. Mortality was significantly increased with...

Research paper thumbnail of Human immune deficiency virus among cervical cancer patients at Tikur Anbessa Specialized Hospital, Ethiopia: a cross sectional study

Background The discrepancy in cervical cancer incidence between women with HIV and women without ... more Background The discrepancy in cervical cancer incidence between women with HIV and women without HIV is highest in low and middle-income countries. In Africa, cervical cancer is the most common cause of cancer death. As a result, HIV-infected women are 6 times more likely to develop cervical cancer than uninfected women. In addition, HIV is associated with several triggering factors for cervical cancer, including multiple sexual partners, early sexual debut, economic status and substance use. Objective To assess the prevalence and associated factors of HIV among cervical cancer patients at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Methods A cross sectional study was conducted among 1057 cervical cancer patients registered from January 1, 2014 to December 31, 2018 at Oncology Center of Tikur Anbessa Specialized Hospital. A structured English version checklist was used to collect the data from patient charts. The pre coded data were entered in to EPI-data version 3.1 ...

Research paper thumbnail of Adherence to Adjuvant Hormonal Therapy and Associated Factors Among Women with Breast Cancer Attending the Tikur Anbessa Specialized Hospital, Addis Ababa Ethiopia, 2019: A Cross-sectional Study

Background In breast cancer patients, adherence to adjuvant hormone therapy (AHT) is uncertain. S... more Background In breast cancer patients, adherence to adjuvant hormone therapy (AHT) is uncertain. Seven in every 10 patients were hormone receptor positive and adjuvant hormone therapy (AHT) is prescribed for 5–10 years for a woman with breast cancer. Therefore, the aim of this research was to examine adherence to adjuvant hormone therapy and related factors among women with breast cancer attending the Tikur Anbessa Specialized Hospital Oncology Center. Methods An institutional-based cross-sectional study was conducted from March to April, 2019. Systematic random sampling technique was used to select participants. A semi-structured questionnaire was used. Medication possession ratio (MPR) was used where score ≥80% was adherence. Data were entered in EpiData version 4.4.2.1 and transferred to SPSS version 25, and analyzed using binary logistic regression. Results Out of 216 women with breast cancer 209 participated in the study with a response rate of 97%. The overall adherence in this...

Research paper thumbnail of Adherence to Adjuvant Hormonal Therapy and Associated Factors Among Women with Breast Cancer Attending the Tikur Anbessa Specialized Hospital, Addis Ababa Ethiopia, 2019: A Cross-sectional Study

Background In breast cancer patients, adherence to adjuvant hormone therapy (AHT) is uncertain. S... more Background In breast cancer patients, adherence to adjuvant hormone therapy (AHT) is uncertain. Seven in every 10 patients were hormone receptor positive and adjuvant hormone therapy (AHT) is prescribed for 5–10 years for a woman with breast cancer. Therefore, the aim of this research was to examine adherence to adjuvant hormone therapy and related factors among women with breast cancer attending the Tikur Anbessa Specialized Hospital Oncology Center. Methods An institutional-based cross-sectional study was conducted from March to April, 2019. Systematic random sampling technique was used to select participants. A semi-structured questionnaire was used. Medication possession ratio (MPR) was used where score ≥80% was adherence. Data were entered in EpiData version 4.4.2.1 and transferred to SPSS version 25, and analyzed using binary logistic regression. Results Out of 216 women with breast cancer 209 participated in the study with a response rate of 97%. The overall adherence in this...

Research paper thumbnail of Knowledge, attitude and practice of breast self examination among female undergraduate nursing students at university of gondar, college of medicine and health sciences

Hospice and Palliative Medicine International Journal

Research paper thumbnail of Incidence and predictors of recurrent acute coronary syndrome among adult patients with acute coronary syndrome in West Amhara, Ethiopia: a multicenter retrospective follow-up study

Frontiers in Cardiovascular Medicine, Oct 15, 2023

Research paper thumbnail of Sleep Quality and Associated Factors Among Adult Cancer Patients Under Treatment at Oncology Units in Amhara Region, Ethiopia

Nature and Science of Sleep, Jun 1, 2022

Poor sleep quality, a common, under-diagnosed, and under-treated problem in cancer patients, has ... more Poor sleep quality, a common, under-diagnosed, and under-treated problem in cancer patients, has negative physical and psychological consequences, but its prevalence and associated factors are not well studied in Ethiopia. Thus, the present study aimed to assess the prevalence of sleep quality and its associated factors among adult cancer patients receiving treatment at oncology units in Amhara region, Ethiopia. Methods and Materials: An institution-based cross-sectional study was conducted among adult patients with cancer under treatment at the oncology units in the Amhara region from April 12 to May 12/2021. A systematic random sampling technique was used to select 423 samples. Data were collected using a structured Interviewer-administered questionnaire. Sleep quality and depression were assessed by the Pittsburgh Sleep Quality Index and depression subscale of Hospital Anxiety and Depression Scale, respectively. Bivariable and multivariable logistic regression analyses were computed, considering p < 0.25 to select candidate variables for multivariable analysis and p < 0.05 to be statistically significant in the final model. Results: A total of 410 cancer patients participated in this study. The mean of the participant's age was 44.2 (range: 20-77) years. More than half (52.7%) of participants received chemotherapy and the remaining were treated with a combination of treatments. Twohundred ninety-three (71.5%) of participants had poor sleep quality and 28.5% had good sleep quality. The factors found to be significantly associated with poor sleep quality were advanced age [AOR = 1.037, 95%

Research paper thumbnail of Knowledge, attitude and practice of breast self examination among female undergraduate nursing students at university of gondar, college of medicine and health sciences

Hospice & palliative medicine international journal, Nov 5, 2019

Introduction: BSE is simple, non-invasive, requires little time and cost free practice and it can... more Introduction: BSE is simple, non-invasive, requires little time and cost free practice and it can be perform by both young and old women. By performing BSE can recognize changes, such as thickening, lumps, spontaneous nipple discharge or skin change, and dimpling. However, the women who not perform BSE are high risk for breast cancer. Breast cancer is the second most frequent occurring cancer among women. Objective: The object of this study to assess the knowledge, attitude and practice of BSE among female undergraduate CMHS, university of Gondar student`s. Methods: An institution based cross sectional study design was conducted at the University of Gondar, collage of medicine and health science from April to June 2018. A total of 300 students were included in this study. The source population was all female undergraduate nursing students. The study was selected by simple random sampling technique. Selfadministered questionnaire was used for data collection. Then data was entered to Epi info version 3.5.4. The enter data was export to SPSS statistical package for analysis. Result: In this study, a total of 300 undergraduate female nursing students participated in the study and giving a response rate of 100% About knowledge of the female undergraduate students with regard to BSE is found to be 55.7% with 95% CI: (56-61%) had knowledge of breast self examination while 176 (56.7%) with 95% CI: (53-64%) of the female undergraduate students have favorable attitude about BSE. Of the total participants, 34 (11.3%) with 95% CI: (7-15%) of the female undergraduate students had practiced Conclusion: In general, the KAP of the participants were, 55.7% with 95% CI: (56-61%), 56.7% with 95% CI: (53-64%) and 11.3% with 95% CI: (7-15%) respectively. This finding showed that the participants had poor KAP toward BSE. Therefore, Universities and other stake holders should plan to promote provision of information, education and communication targeting females, and the general community to increase awareness to ward breast self examination.

Research paper thumbnail of Postpartum depression and associated factor among mothers attending public health centers of Yeka sub city, addis ababa Ethiopia

Research paper thumbnail of Sleep Quality and Associated Factors Among Adult Cancer Patients Under Treatment at Oncology Units in Amhara Region, Ethiopia

Nature and Science of Sleep

Poor sleep quality, a common, under-diagnosed, and under-treated problem in cancer patients, has ... more Poor sleep quality, a common, under-diagnosed, and under-treated problem in cancer patients, has negative physical and psychological consequences, but its prevalence and associated factors are not well studied in Ethiopia. Thus, the present study aimed to assess the prevalence of sleep quality and its associated factors among adult cancer patients receiving treatment at oncology units in Amhara region, Ethiopia. Methods and Materials: An institution-based cross-sectional study was conducted among adult patients with cancer under treatment at the oncology units in the Amhara region from April 12 to May 12/2021. A systematic random sampling technique was used to select 423 samples. Data were collected using a structured Interviewer-administered questionnaire. Sleep quality and depression were assessed by the Pittsburgh Sleep Quality Index and depression subscale of Hospital Anxiety and Depression Scale, respectively. Bivariable and multivariable logistic regression analyses were computed, considering p < 0.25 to select candidate variables for multivariable analysis and p < 0.05 to be statistically significant in the final model. Results: A total of 410 cancer patients participated in this study. The mean of the participant's age was 44.2 (range: 20-77) years. More than half (52.7%) of participants received chemotherapy and the remaining were treated with a combination of treatments. Twohundred ninety-three (71.5%) of participants had poor sleep quality and 28.5% had good sleep quality. The factors found to be significantly associated with poor sleep quality were advanced age [AOR = 1.037, 95%

Research paper thumbnail of The Impact of Impaired Swallowing Related Quality of Life of Head and Neck Cancer Survivors at Tikur Anbessa Specialized Referral Hospital, Addis Ababa, Ethiopia: 2019 G.C (Mixed Method Study)

Introduction: Different research and international clinical guidelines deals about the importance... more Introduction: Different research and international clinical guidelines deals about the importance of addressing and supporting the Quality of Life needs of individuals with impaired swallowing. However, data support that the presence of swallowing impairment related Quality of Life has not directly addressed in the reviewed studies in Ethiopia. Objective: This study was conducted to assess factors that affect swallowing related quality of life and it is impacts in head and neck cancer survivors. Methods: To achieve the objective of this study 102 patients were enrolled in cross sectional study, of whom 7 were purposively selected for in depth interviews of qualitative study. The study was conducted from March to April 2019 G.C at the oncology center of Tikur Anbessa Specialized Referral Hospital, Addis Ababa, Ethiopia. The pre coded data was entered in to EpiData version 4.4.3.1 then exported to Statistical Package for the Social Sciences version 24 for further cleaning, and analysi...

Research paper thumbnail of Determinants of Mortality among Cervical Cancer Patients Attending in Tikur Anbessa Specialized Hospital, Ethiopia: Institutional-Based Retrospective Study

Background Globally, about 570,000 cases and 311,000 deaths of cervical cancer occurred in 2018. ... more Background Globally, about 570,000 cases and 311,000 deaths of cervical cancer occurred in 2018. It was the leading cause of cancer-related deaths among women in Africa. The global mean age at death of cervical cancer was about 59 years. This study aimed to assess the determinants of cervical cancer mortality among cervical cancer patients attending in Tikur Anbessa Specialized Hospital (TASH). Methods Institutional-based retrospective cohort study was conducted in the oncology center of TASH, Ethiopia, from March to April 2019. Data were extracted from patients' chart using structured checklist and analyzed using Stata 14.2. Cox regression was used to identify variables that affect the outcome variable. Result From the total of 2045 reviewed medical records of cervical cancer patients, 1057 medical records were found to be complete and included in this study. The incidence of mortality among cervical cancer patients was 15.6/100/years. Mortality was significantly increased with...

Research paper thumbnail of Human immune deficiency virus among cervical cancer patients at Tikur Anbessa Specialized Hospital, Ethiopia: a cross sectional study

Background The discrepancy in cervical cancer incidence between women with HIV and women without ... more Background The discrepancy in cervical cancer incidence between women with HIV and women without HIV is highest in low and middle-income countries. In Africa, cervical cancer is the most common cause of cancer death. As a result, HIV-infected women are 6 times more likely to develop cervical cancer than uninfected women. In addition, HIV is associated with several triggering factors for cervical cancer, including multiple sexual partners, early sexual debut, economic status and substance use. Objective To assess the prevalence and associated factors of HIV among cervical cancer patients at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Methods A cross sectional study was conducted among 1057 cervical cancer patients registered from January 1, 2014 to December 31, 2018 at Oncology Center of Tikur Anbessa Specialized Hospital. A structured English version checklist was used to collect the data from patient charts. The pre coded data were entered in to EPI-data version 3.1 ...

Research paper thumbnail of Adherence to Adjuvant Hormonal Therapy and Associated Factors Among Women with Breast Cancer Attending the Tikur Anbessa Specialized Hospital, Addis Ababa Ethiopia, 2019: A Cross-sectional Study

Background In breast cancer patients, adherence to adjuvant hormone therapy (AHT) is uncertain. S... more Background In breast cancer patients, adherence to adjuvant hormone therapy (AHT) is uncertain. Seven in every 10 patients were hormone receptor positive and adjuvant hormone therapy (AHT) is prescribed for 5–10 years for a woman with breast cancer. Therefore, the aim of this research was to examine adherence to adjuvant hormone therapy and related factors among women with breast cancer attending the Tikur Anbessa Specialized Hospital Oncology Center. Methods An institutional-based cross-sectional study was conducted from March to April, 2019. Systematic random sampling technique was used to select participants. A semi-structured questionnaire was used. Medication possession ratio (MPR) was used where score ≥80% was adherence. Data were entered in EpiData version 4.4.2.1 and transferred to SPSS version 25, and analyzed using binary logistic regression. Results Out of 216 women with breast cancer 209 participated in the study with a response rate of 97%. The overall adherence in this...

Research paper thumbnail of Adherence to Adjuvant Hormonal Therapy and Associated Factors Among Women with Breast Cancer Attending the Tikur Anbessa Specialized Hospital, Addis Ababa Ethiopia, 2019: A Cross-sectional Study

Background In breast cancer patients, adherence to adjuvant hormone therapy (AHT) is uncertain. S... more Background In breast cancer patients, adherence to adjuvant hormone therapy (AHT) is uncertain. Seven in every 10 patients were hormone receptor positive and adjuvant hormone therapy (AHT) is prescribed for 5–10 years for a woman with breast cancer. Therefore, the aim of this research was to examine adherence to adjuvant hormone therapy and related factors among women with breast cancer attending the Tikur Anbessa Specialized Hospital Oncology Center. Methods An institutional-based cross-sectional study was conducted from March to April, 2019. Systematic random sampling technique was used to select participants. A semi-structured questionnaire was used. Medication possession ratio (MPR) was used where score ≥80% was adherence. Data were entered in EpiData version 4.4.2.1 and transferred to SPSS version 25, and analyzed using binary logistic regression. Results Out of 216 women with breast cancer 209 participated in the study with a response rate of 97%. The overall adherence in this...

Research paper thumbnail of Knowledge, attitude and practice of breast self examination among female undergraduate nursing students at university of gondar, college of medicine and health sciences

Hospice and Palliative Medicine International Journal