Kardinah Kardinah | University of Indonesia (original) (raw)

Papers by Kardinah Kardinah

Research paper thumbnail of The Global Reading Room: Performing a Core-Needle Breast Biopsy

American Journal of Roentgenology, Jan 2, 2024

Research paper thumbnail of The Debulking of Recurrent Right Testicular Seminoma with Anterolateral Thigh Flap Reconstruction

Indonesian Journal of Cancer

Introduction: Radical orchidectomy is considered both a therapy and a part of the staging procedu... more Introduction: Radical orchidectomy is considered both a therapy and a part of the staging procedure. Stage I seminoma may be treated with orchiectomy alone while the remaining 15% to 20% may have a relapse if they receive no additional treatment during the five-year surveillance. Most recurrences occur within the first 2 years after diagnosis, and the location of the recurrence is typically in the retroperitoneum. This article aims to share the experience in the management of testicular seminoma recurrence in a multidisciplinary approach.Case Presentation: We are reporting a case of a 26-year-old male with a growing mass at the right scrotum just two months after right radical orchidectomy. This patient was previously treated with a stage I seminoma and underwent surveillance. Tumor debulking and right inguinoscrotal reconstruction using a pedicled anterolateral thigh (ALT) flap were done through collaborative surgery between urology and plastic surgery. However, according to Nation...

Research paper thumbnail of International Interobserver Variability of Breast Density Assessment

Journal of the American College of Radiology

Research paper thumbnail of Contextualizing policy implementation, challenges, and plans for improving breast cancer early detection programs in Indonesia

Background Late-stage breast cancer (BC) is commonly diagnosed in limited-resource countries such... more Background Late-stage breast cancer (BC) is commonly diagnosed in limited-resource countries such as Indonesia. The lack of information for decision-making emphasizes the need for efforts to support evidence-informed practice for improving BC early detection in Indonesia. This study attempts to understand the local context evidence on policy implementation, challenges, and plans for enhancing BC early detection programs in Indonesia. The evidence gained from this study will help harness the power of scientific reasoning that shapes theories of how BC early detection intervention works and its operationalization in practice. Methods This study engaged three interrelated phases of qualitative methods. Phase I involved a document analysis in determining the predominant strategy and approach to the landscape of BC early detection programs. Phase II was an in-depth interview to clarify the operationalization of the technical aspect, eliciting stakeholder experiences and their perceptions...

Research paper thumbnail of Penelitian Pendahuluan: Pelatihan Pemeriksaan Payudara bagi Tenaga Medis RS. Kanker Dharmais

Indonesian Journal of Cancer

Indonesia mempunyai masalah yang sama dengan negara berkembang lainnya yaitu pasien kanker payuda... more Indonesia mempunyai masalah yang sama dengan negara berkembang lainnya yaitu pasien kanker payudara yang datang ke rumah sakit dalam stadium lanjut. Oleh karena itu diperlukan upaya peningkatan kepedulian khususnya di lingkup tenaga medis terhadap kanker payudara melalui penyuluhan dan ketrampilan pemeriksaan payudara. Tujuan penelitian ini adalah mengumpulkan data awal untuk menentukan metode yang tepat untuk pelatihan pemeriksaan payudara bagi tenaga medis khususnya perawat, bidan dan dokter umum.Dilakukan penyuluhan bagi staf medis yang berminat dan pelatihan pemeriksaan payudara pada tenaga medis (perawat dan bidan) di RS.Kanker Dharmais periode April - Desember 2005. Untuk meningkatkan kepedulian dan kemampuan ketrampilan pemeriksaan payudara para peserta kemudian diminta untuk memberikan penyuluhan di lingkungannya dan mengajak wanita yang bersedia dilakukan pemeriksaan payudara dan USG payudara di RS. Kanker Dharmais.Sebanyak 25 orang perawat dan bidan serta 1 orang dokter um...

Research paper thumbnail of An Asian Body to Tackle Cancers in Asia – The Asian National Cancer Centers Alliance

Asian Pacific Journal of Cancer Prevention

Research paper thumbnail of Strategi RS. Kanker "Dharmais" sebagai Bagian dari Pusat Kanker Nasional dalam Mengimplementasikan Kebijakan Departemen Kesehatan

Indonesian Journal of Cancer

Pada bulan Oktober 2007 Rumah Sakit Kanker "Dharmais" genap berdiri selama 14 tahun dan... more Pada bulan Oktober 2007 Rumah Sakit Kanker "Dharmais" genap berdiri selama 14 tahun dan merupakan tantangan bagi pihak rumah sakit untuk menjawab berbagai masalah yang timbul khususnya di bidang kanker. Kebijakan Departemen Kesehatan untuk menurunkan angka kesakitan dan kematian akibat penyakit kanker, memperpanjang umur harapan hidup serta meningkatkan kualitas hidup penderita dilaksanakan dengan strategi sebagai berikut; menggerakkan dan memberdayakan masyarakat untuk hidup sehat , meningkatkan akses masyarakat terhadap pelayanan kesehatan yang berkualitas, meningkatkan sistem surveilans, monitoring dan informasi kesehatan dan meningkatkan pembiayaan kesehatan.

Research paper thumbnail of 体侧联胎一例报告

Research paper thumbnail of Evaluasi Dosis Glandular dalam Pemeriksaan Mammografi

Indonesian Journal of Cancer

Telah dilakukan pengukuran dosis rata-rata Glandular (mean glandular dose) pada pemeriksaan mammo... more Telah dilakukan pengukuran dosis rata-rata Glandular (mean glandular dose) pada pemeriksaan mammografi dengan menggunakan Thermoluminiscence Dosimeter (TLD) terhadap 49 pasien. Dosis yang terbaca pada TLD adalah Entrance Surface Dose (ESD) dengan nilai rata-rata yang didapat 7.6(±’b1 3.9) mGy. Untuk konversi ke nilai mean glandular dose, nilai ESD dikalikan dengan nilai Dgn (ESD dengan factor konversi average glandular dose per unit exposure) yang terkonversi dengan memperhitungkan prosentase glandular terhadap adipose. Data Dgn diperoleh dari perhitungan Jhon M Boone yang menggunakan metode Monte Carlo yang masih tergantung dari nilai HVL dan ketebalan payudara. Prosentase glandular terhadap adipose dihitung dengan menggunakan metoda analisa film Nooriah Djamal. Kemudian nilai Dgn 0% glandular untuk kontribusi adipose maupun Dgn 100% glandular untuk kontribusi glandular diperoleh dari table Dgn Boone. Nilai MGD yang diperoleh adalah 1.818 (±’b1 0.615) mGy. Nilai masih dibawah limi...

Research paper thumbnail of Kegemukan Dan Frekuensi Konsumsi Makanan Berlemak Yang Tinggi Merupakan Faktor Risiko Perlemakan Hati Pada Pasien Kanker Payudara Dengan Pemeriksaan Ultrasonografi Di Rumah Sakit Kanker Dharmais, Jakarta

Indonesian Journal of Cancer, Dec 5, 2015

ABSTRACT Fatty liver is a term applied to wide spectrum of conditions characterized hispatologica... more ABSTRACT Fatty liver is a term applied to wide spectrum of conditions characterized hispatologically by trigliseride accumulation within the cytoplasm of hepatocytes which is examined using ultrasound. This study was aimed to identify the risk factors affecting fatty liver in the patients with breast cancer on ultrasound examination at Dharmais Cancer Hospital Jakarta. The design was a cross sectional study with 70 subjects, consisted of 37 fatty liver subjects and 33 normal subjects. The result showed that risk factors of fatty liver in patient with breast cancer were overweight and obesity (Body Mass Index ≥25 kg/m2) (OR : 5.5, 95%CI : 1.881 – 16.243) and high frequency of dietary fat (OR: 3.8, 95%CI : 1.084 – 13.445). ABSTRAK Perlemakan hati merupakan akumulasi asam lemak dalam bentuk trigliserida di dalam sitoplasma hepatosit yang diperiksa dengan menggunakan alat ultrasonografi.Tujuan penelitian ini adalah untuk mengetahui faktor risiko yang berpengaruh terhadap kejadian perlemakan hati pada pasien kanker payudara dengan pemeriksaan ultrasonografi di Rumah Sakit Kanker “Dharmais”, Jakarta. Desain penelitian ini adalah cross sectional study, dengan subjek penelitian berjumlah 70 orang yang terdiri dari 37 contoh perlemakan hati dan 33 contoh normal. Hasil analisis menunjukkan bahwa faktor risiko perlemakan hati pada pasien kanker payudara adalah kegemukan (overweight dan obes, Indeks Massa Tubuh ≥ 25 kg/m2) (OR=5.5, 95%CI : 1.881 – 16.243) dan tingginya frekuensi konsumsi makanan berlemak (OR=3.8, 95%CI : 1.084 – 13.455)

Research paper thumbnail of Literature in America

Research paper thumbnail of Spectral Analysis of Proton-Irradiated Natural MoO3 Relevant for Technetium-99m Radionuclide Production

Due to the declining number of available nuclear reactors capable of Tc-99m production and tight ... more Due to the declining number of available nuclear reactors capable of Tc-99m production and tight regulations related to uranium enrichment, cyclotron-based Tc-99m production has recently been suggested as a new method to help ease Tc-99m supply shortages. In this investigation, a solid natural MoO 3 target was irradiated using 11-MeV proton beams at variable proton doses. The proton doses were varied by varying the irradiation time while keeping the proton beam current constant at 20 µA. At the end of the bombardment, the post-irradiated solid MoO 3 targets were analyzed for their radioactive contents using a portable gamma-ray spectroscopy system. The analysis was also performed for the post-irradiated targets after dissolving the solid MoO 3 in a 6M NaOH solution. The experimental results indicated that as much as 75.71% of Tc-99m radioactivity was directly generated via a 100 Mo(p,2n) 99m Tc nuclear reaction, while the rest of the Tc-99m radioactivity was a result of a 98 Mo(n,γ)...

Research paper thumbnail of Production of F-18 and Tc-99m Radionuclides using an 11 MeV Proton Accelerating Cyclotron

An 11-MeV proton-accelerating cyclotron has been employed to produce F-18 and Tc-99m radionuclide... more An 11-MeV proton-accelerating cyclotron has been employed to produce F-18 and Tc-99m radionuclides. In this report, F-18 radionuclide was produced from enriched-water (H2O) target whereas Tc-99m was generated from natural molybdenum trioxide (MoO3) target. Two recoiled radioactive impurities such as Co-56 and Ag110m are identified in the F-18 solution whereas N-13 was recognized as an impurity in the Tc-99m production. The Co-56 radionuclidic impurity is presumably sputtered off the havar window in the target system whereas Ag110m is originally from a silver body housing the enriched water target which is generated by secondary neutron irradiated Ag-109. In addition, N-13 impurity found in the post-irradiated MoO3 target occurs presumably via (p,α) nuclear reaction.

Research paper thumbnail of Risk factors of deep vein thrombosis in cancer patients

Iranian Journal of Blood and Cancer, 2018

Background: Venous thromboembolism (VTE) is a significant complication in cancer patients which w... more Background: Venous thromboembolism (VTE) is a significant complication in cancer patients which was found in 4-20% of the patients. This study was aimed to evaluate risk factors of deep vein thrombosis (DVT) in cancer patients in an oncology center in Indonesia. Methods: This was a retrospective cohort study. Data were obtained from medical records of adult cancer patients with DVT referring to Dharmais National Cancer Center in Indonesia since 2013-2016. Control group were adult cancer patients without DVT. Association of risk factors (sex, age, presence of metastasis, Khorana score, complete blood count and D-dimer level) with DVT were compared and analyzed between DVT patients and control group. Results: A total of 129 cancer patients with DVT at Dharmais Cancer Hospital during year 2013-2016 met the inclusion criteria. Median age of the patients was 56 years old. Multivariate logistic regression analysis was performed to investigate the effect of sex, age, hypertension, diabetes...

Research paper thumbnail of Breast Cancer and Malignant Melanoma Preoperative Lymphoscintigraphy in Dharmais Cancer Hospital

Pemeriksaan limfoskintigrafi sebagai pemetaan kelenjar getah bening preoperatif telah banyak dite... more Pemeriksaan limfoskintigrafi sebagai pemetaan kelenjar getah bening preoperatif telah banyak diteliti khususnya pada pasien kanker payudara dan melanoma maligna sebagai bagian dari prosedur sentinel node. Prosedur ini telah diterapkan pula di RS. Kanker "Dharmais" dimana dilakukan injeksi isotop preoperatif, injeksi blue dye dan penggunaan gamma probe intraoperatif. Dilaporkan 48 pasien kanker payudara dan 5 pasien melanoma maligna yang menjalani prosedur limfoskintigrafi. Sebanyak 75.7% dari 37 pasien breast conserving treatment ditemukan positif limfoskintigrafi sedangkan seluruh pasien melanoma maligna didapatkan hasil positif limfoskintigrafi. Dengan menggunakan blue dye dan gamma probe intraoperatif, sentinel node dapat diidentifikasi walaupun hasil limfoskintigrafi negatif. Preoperatif limfoskintigrafi merupakan komplemen prosedur sentinel node dimana hasil pemetaannya akan memberikan arahan saat operasi. Kata kunci: kanker payudara, melanoma maligna, limfoskintigraf...

Research paper thumbnail of Kegemukan Dan Frekuensi Konsumsi Makanan Berlemak Yang Tinggi Merupakan Faktor Risiko Perlemakan Hati Pada Pasien Kanker Payudara Dengan Pemeriksaan Ultrasonografi Di Rumah Sakit Kanker Dharmais, Jakarta

Indonesian Journal of Cancer, 2015

Fatty liver is a term applied to wide spectrum of conditions characterized hispatologically by tr... more Fatty liver is a term applied to wide spectrum of conditions characterized hispatologically by trigliseride accumulation within the cytoplasm of hepatocytes which is examined using ultrasound. This study was aimed to identify the risk factors affecting fatty liver in the patients with breast cancer on ultrasound examination at Dharmais Cancer Hospital Jakarta. The design was a cross sectional study with 70 subjects, consisted of 37 fatty liver subjects and 33 normal subjects. The result showed that risk factors of fatty liver in patient with breast cancer were overweight and obesity (Body Mass Index ≥25 kg/m2) (OR : 5.5, 95%CI : 1.881 – 16.243) and high frequency of dietary fat (OR: 3.8, 95%CI : 1.084 – 13.445). ABSTRAK Perlemakan hati merupakan akumulasi asam lemak dalam bentuk trigliserida di dalam sitoplasma hepatosit yang diperiksa dengan menggunakan alat ultrasonografi.Tujuan penelitian ini adalah untuk mengetahui faktor risiko yang berpengaruh terhadap kejadian perlemakan hati...

Research paper thumbnail of Rumah Sakit Kanker Dharmais (Pusat Kanker Nasional): Melangkah Untuk Melaksanakan Program Penanggulangan Kanker Di Indonesia

Indonesian Journal of Cancer, 2008

Ketika anak terdiagnosis menderita kanker maka orangtua akan merasakan hal ini sebagai sesuatu ya... more Ketika anak terdiagnosis menderita kanker maka orangtua akan merasakan hal ini sebagai sesuatu yang mengejutkan dan pukulan yang berat, terutama bagi sang ibu, yang telah melahirkan dan umumnya menjadi pengasuh utama anak. Melalui penelitian ini, penulis membahas secara mendalam mengenai emosi-emosi yang dirasakan oleh ibu ditinjau dari teori Colin Murray Parkes. Parkes membagi emosi ke dalam empat fase yaitu: (a) shock, numbness, and disbelief; (b) acute distress, anger, and protest; (c) depression and despair; dan (d) acceptance and resolution. Dari penelitian didapatkan bahwa fase-fase tersebut timbul secara tidak berurutan dan berbeda untuk setiap individu. Perbedaan individu dipengaruhi oleh berbagai hal antara lain kepribadian subyek, dukungan sosial, kondisi fisik anak, dan prediksi yang dilakukan individu. Selain itu, reiigiusitas juga terbukti menjadi faktor penting untuk membantu ibu menerima Kenyataan yang harus dihadapi.

Research paper thumbnail of Telaah Awal Pemetaan Indikasi Pemeriksaan 18F-FDG PET/CT di RS Kanker "Dharmais" dengan Pedoman Appropriateness Criteria dari IAEA

Research paper thumbnail of A Qualitative Study: Early Detection of Breast Cancer in Indonesia (After Universal Health Coverage Implementation)

ObjectivesEarly detection is of vital importance in breast cancer management. BPJS Kesehatan, as ... more ObjectivesEarly detection is of vital importance in breast cancer management. BPJS Kesehatan, as Indonesia’s national health insurance, is expected to provide an adequate health service for breast cancer patients. This study aimed to obtain insight into the current conditions of health care services in Indonesia, related to early detection of breast cancer, particularly after BPJS Kesehatan implementation. MethodsThe study was conducted in 2017 in Yogyakarta, Indonesia with a wide range of socio-demographic backgrounds. Subjects comprised breast cancer patients and their relatives, health care professionals (HCPs), and healthy women from the general population who had no history of breast cancer and no family members with breast cancer. The subjects’ experiences and knowledge of health care services regarding early detection of breast cancer, were investigated through in-depth interviews. The thematic analysis guided the result synthesis from semi-structured in-depth interviews with...

Research paper thumbnail of An Asian Body to Tackle Cancers in Asia – The Asian National Cancer Centers Alliance

Asian Pacific Journal of Cancer Prevention

The socioeconomic burden of cancer is growing rapidly in the Asian region, with a concentrated bu... more The socioeconomic burden of cancer is growing rapidly in the Asian region, with a concentrated burden on low-and middle-income countries. The residents of this region, representing almost 60% of the global population, demonstrate an eclectic and complex nature, with huge disparities in ethnicity, sociocultural practices among others. The Asian National Cancer Centers Alliance (ANCCA) was established in 2005 by heads of several national cancer centers (NCCs) in the region to address common issues and concerns among Asian countries. During the first 13 years of ANCCA's existence, the participating NCCs' senior managers paved the way toward collaboration through transparent sharing of key facts and activities. Concrete achievements of the Alliance include the Asia Tobacco-Free Declaration, the establishment of the ANCCA Constitution in 2014 as well as the creation of an official website more recently. In November 2019, the most active ANCCA members (

Research paper thumbnail of The Global Reading Room: Performing a Core-Needle Breast Biopsy

American Journal of Roentgenology, Jan 2, 2024

Research paper thumbnail of The Debulking of Recurrent Right Testicular Seminoma with Anterolateral Thigh Flap Reconstruction

Indonesian Journal of Cancer

Introduction: Radical orchidectomy is considered both a therapy and a part of the staging procedu... more Introduction: Radical orchidectomy is considered both a therapy and a part of the staging procedure. Stage I seminoma may be treated with orchiectomy alone while the remaining 15% to 20% may have a relapse if they receive no additional treatment during the five-year surveillance. Most recurrences occur within the first 2 years after diagnosis, and the location of the recurrence is typically in the retroperitoneum. This article aims to share the experience in the management of testicular seminoma recurrence in a multidisciplinary approach.Case Presentation: We are reporting a case of a 26-year-old male with a growing mass at the right scrotum just two months after right radical orchidectomy. This patient was previously treated with a stage I seminoma and underwent surveillance. Tumor debulking and right inguinoscrotal reconstruction using a pedicled anterolateral thigh (ALT) flap were done through collaborative surgery between urology and plastic surgery. However, according to Nation...

Research paper thumbnail of International Interobserver Variability of Breast Density Assessment

Journal of the American College of Radiology

Research paper thumbnail of Contextualizing policy implementation, challenges, and plans for improving breast cancer early detection programs in Indonesia

Background Late-stage breast cancer (BC) is commonly diagnosed in limited-resource countries such... more Background Late-stage breast cancer (BC) is commonly diagnosed in limited-resource countries such as Indonesia. The lack of information for decision-making emphasizes the need for efforts to support evidence-informed practice for improving BC early detection in Indonesia. This study attempts to understand the local context evidence on policy implementation, challenges, and plans for enhancing BC early detection programs in Indonesia. The evidence gained from this study will help harness the power of scientific reasoning that shapes theories of how BC early detection intervention works and its operationalization in practice. Methods This study engaged three interrelated phases of qualitative methods. Phase I involved a document analysis in determining the predominant strategy and approach to the landscape of BC early detection programs. Phase II was an in-depth interview to clarify the operationalization of the technical aspect, eliciting stakeholder experiences and their perceptions...

Research paper thumbnail of Penelitian Pendahuluan: Pelatihan Pemeriksaan Payudara bagi Tenaga Medis RS. Kanker Dharmais

Indonesian Journal of Cancer

Indonesia mempunyai masalah yang sama dengan negara berkembang lainnya yaitu pasien kanker payuda... more Indonesia mempunyai masalah yang sama dengan negara berkembang lainnya yaitu pasien kanker payudara yang datang ke rumah sakit dalam stadium lanjut. Oleh karena itu diperlukan upaya peningkatan kepedulian khususnya di lingkup tenaga medis terhadap kanker payudara melalui penyuluhan dan ketrampilan pemeriksaan payudara. Tujuan penelitian ini adalah mengumpulkan data awal untuk menentukan metode yang tepat untuk pelatihan pemeriksaan payudara bagi tenaga medis khususnya perawat, bidan dan dokter umum.Dilakukan penyuluhan bagi staf medis yang berminat dan pelatihan pemeriksaan payudara pada tenaga medis (perawat dan bidan) di RS.Kanker Dharmais periode April - Desember 2005. Untuk meningkatkan kepedulian dan kemampuan ketrampilan pemeriksaan payudara para peserta kemudian diminta untuk memberikan penyuluhan di lingkungannya dan mengajak wanita yang bersedia dilakukan pemeriksaan payudara dan USG payudara di RS. Kanker Dharmais.Sebanyak 25 orang perawat dan bidan serta 1 orang dokter um...

Research paper thumbnail of An Asian Body to Tackle Cancers in Asia – The Asian National Cancer Centers Alliance

Asian Pacific Journal of Cancer Prevention

Research paper thumbnail of Strategi RS. Kanker "Dharmais" sebagai Bagian dari Pusat Kanker Nasional dalam Mengimplementasikan Kebijakan Departemen Kesehatan

Indonesian Journal of Cancer

Pada bulan Oktober 2007 Rumah Sakit Kanker "Dharmais" genap berdiri selama 14 tahun dan... more Pada bulan Oktober 2007 Rumah Sakit Kanker "Dharmais" genap berdiri selama 14 tahun dan merupakan tantangan bagi pihak rumah sakit untuk menjawab berbagai masalah yang timbul khususnya di bidang kanker. Kebijakan Departemen Kesehatan untuk menurunkan angka kesakitan dan kematian akibat penyakit kanker, memperpanjang umur harapan hidup serta meningkatkan kualitas hidup penderita dilaksanakan dengan strategi sebagai berikut; menggerakkan dan memberdayakan masyarakat untuk hidup sehat , meningkatkan akses masyarakat terhadap pelayanan kesehatan yang berkualitas, meningkatkan sistem surveilans, monitoring dan informasi kesehatan dan meningkatkan pembiayaan kesehatan.

Research paper thumbnail of 体侧联胎一例报告

Research paper thumbnail of Evaluasi Dosis Glandular dalam Pemeriksaan Mammografi

Indonesian Journal of Cancer

Telah dilakukan pengukuran dosis rata-rata Glandular (mean glandular dose) pada pemeriksaan mammo... more Telah dilakukan pengukuran dosis rata-rata Glandular (mean glandular dose) pada pemeriksaan mammografi dengan menggunakan Thermoluminiscence Dosimeter (TLD) terhadap 49 pasien. Dosis yang terbaca pada TLD adalah Entrance Surface Dose (ESD) dengan nilai rata-rata yang didapat 7.6(±’b1 3.9) mGy. Untuk konversi ke nilai mean glandular dose, nilai ESD dikalikan dengan nilai Dgn (ESD dengan factor konversi average glandular dose per unit exposure) yang terkonversi dengan memperhitungkan prosentase glandular terhadap adipose. Data Dgn diperoleh dari perhitungan Jhon M Boone yang menggunakan metode Monte Carlo yang masih tergantung dari nilai HVL dan ketebalan payudara. Prosentase glandular terhadap adipose dihitung dengan menggunakan metoda analisa film Nooriah Djamal. Kemudian nilai Dgn 0% glandular untuk kontribusi adipose maupun Dgn 100% glandular untuk kontribusi glandular diperoleh dari table Dgn Boone. Nilai MGD yang diperoleh adalah 1.818 (±’b1 0.615) mGy. Nilai masih dibawah limi...

Research paper thumbnail of Kegemukan Dan Frekuensi Konsumsi Makanan Berlemak Yang Tinggi Merupakan Faktor Risiko Perlemakan Hati Pada Pasien Kanker Payudara Dengan Pemeriksaan Ultrasonografi Di Rumah Sakit Kanker Dharmais, Jakarta

Indonesian Journal of Cancer, Dec 5, 2015

ABSTRACT Fatty liver is a term applied to wide spectrum of conditions characterized hispatologica... more ABSTRACT Fatty liver is a term applied to wide spectrum of conditions characterized hispatologically by trigliseride accumulation within the cytoplasm of hepatocytes which is examined using ultrasound. This study was aimed to identify the risk factors affecting fatty liver in the patients with breast cancer on ultrasound examination at Dharmais Cancer Hospital Jakarta. The design was a cross sectional study with 70 subjects, consisted of 37 fatty liver subjects and 33 normal subjects. The result showed that risk factors of fatty liver in patient with breast cancer were overweight and obesity (Body Mass Index ≥25 kg/m2) (OR : 5.5, 95%CI : 1.881 – 16.243) and high frequency of dietary fat (OR: 3.8, 95%CI : 1.084 – 13.445). ABSTRAK Perlemakan hati merupakan akumulasi asam lemak dalam bentuk trigliserida di dalam sitoplasma hepatosit yang diperiksa dengan menggunakan alat ultrasonografi.Tujuan penelitian ini adalah untuk mengetahui faktor risiko yang berpengaruh terhadap kejadian perlemakan hati pada pasien kanker payudara dengan pemeriksaan ultrasonografi di Rumah Sakit Kanker “Dharmais”, Jakarta. Desain penelitian ini adalah cross sectional study, dengan subjek penelitian berjumlah 70 orang yang terdiri dari 37 contoh perlemakan hati dan 33 contoh normal. Hasil analisis menunjukkan bahwa faktor risiko perlemakan hati pada pasien kanker payudara adalah kegemukan (overweight dan obes, Indeks Massa Tubuh ≥ 25 kg/m2) (OR=5.5, 95%CI : 1.881 – 16.243) dan tingginya frekuensi konsumsi makanan berlemak (OR=3.8, 95%CI : 1.084 – 13.455)

Research paper thumbnail of Literature in America

Research paper thumbnail of Spectral Analysis of Proton-Irradiated Natural MoO3 Relevant for Technetium-99m Radionuclide Production

Due to the declining number of available nuclear reactors capable of Tc-99m production and tight ... more Due to the declining number of available nuclear reactors capable of Tc-99m production and tight regulations related to uranium enrichment, cyclotron-based Tc-99m production has recently been suggested as a new method to help ease Tc-99m supply shortages. In this investigation, a solid natural MoO 3 target was irradiated using 11-MeV proton beams at variable proton doses. The proton doses were varied by varying the irradiation time while keeping the proton beam current constant at 20 µA. At the end of the bombardment, the post-irradiated solid MoO 3 targets were analyzed for their radioactive contents using a portable gamma-ray spectroscopy system. The analysis was also performed for the post-irradiated targets after dissolving the solid MoO 3 in a 6M NaOH solution. The experimental results indicated that as much as 75.71% of Tc-99m radioactivity was directly generated via a 100 Mo(p,2n) 99m Tc nuclear reaction, while the rest of the Tc-99m radioactivity was a result of a 98 Mo(n,γ)...

Research paper thumbnail of Production of F-18 and Tc-99m Radionuclides using an 11 MeV Proton Accelerating Cyclotron

An 11-MeV proton-accelerating cyclotron has been employed to produce F-18 and Tc-99m radionuclide... more An 11-MeV proton-accelerating cyclotron has been employed to produce F-18 and Tc-99m radionuclides. In this report, F-18 radionuclide was produced from enriched-water (H2O) target whereas Tc-99m was generated from natural molybdenum trioxide (MoO3) target. Two recoiled radioactive impurities such as Co-56 and Ag110m are identified in the F-18 solution whereas N-13 was recognized as an impurity in the Tc-99m production. The Co-56 radionuclidic impurity is presumably sputtered off the havar window in the target system whereas Ag110m is originally from a silver body housing the enriched water target which is generated by secondary neutron irradiated Ag-109. In addition, N-13 impurity found in the post-irradiated MoO3 target occurs presumably via (p,α) nuclear reaction.

Research paper thumbnail of Risk factors of deep vein thrombosis in cancer patients

Iranian Journal of Blood and Cancer, 2018

Background: Venous thromboembolism (VTE) is a significant complication in cancer patients which w... more Background: Venous thromboembolism (VTE) is a significant complication in cancer patients which was found in 4-20% of the patients. This study was aimed to evaluate risk factors of deep vein thrombosis (DVT) in cancer patients in an oncology center in Indonesia. Methods: This was a retrospective cohort study. Data were obtained from medical records of adult cancer patients with DVT referring to Dharmais National Cancer Center in Indonesia since 2013-2016. Control group were adult cancer patients without DVT. Association of risk factors (sex, age, presence of metastasis, Khorana score, complete blood count and D-dimer level) with DVT were compared and analyzed between DVT patients and control group. Results: A total of 129 cancer patients with DVT at Dharmais Cancer Hospital during year 2013-2016 met the inclusion criteria. Median age of the patients was 56 years old. Multivariate logistic regression analysis was performed to investigate the effect of sex, age, hypertension, diabetes...

Research paper thumbnail of Breast Cancer and Malignant Melanoma Preoperative Lymphoscintigraphy in Dharmais Cancer Hospital

Pemeriksaan limfoskintigrafi sebagai pemetaan kelenjar getah bening preoperatif telah banyak dite... more Pemeriksaan limfoskintigrafi sebagai pemetaan kelenjar getah bening preoperatif telah banyak diteliti khususnya pada pasien kanker payudara dan melanoma maligna sebagai bagian dari prosedur sentinel node. Prosedur ini telah diterapkan pula di RS. Kanker "Dharmais" dimana dilakukan injeksi isotop preoperatif, injeksi blue dye dan penggunaan gamma probe intraoperatif. Dilaporkan 48 pasien kanker payudara dan 5 pasien melanoma maligna yang menjalani prosedur limfoskintigrafi. Sebanyak 75.7% dari 37 pasien breast conserving treatment ditemukan positif limfoskintigrafi sedangkan seluruh pasien melanoma maligna didapatkan hasil positif limfoskintigrafi. Dengan menggunakan blue dye dan gamma probe intraoperatif, sentinel node dapat diidentifikasi walaupun hasil limfoskintigrafi negatif. Preoperatif limfoskintigrafi merupakan komplemen prosedur sentinel node dimana hasil pemetaannya akan memberikan arahan saat operasi. Kata kunci: kanker payudara, melanoma maligna, limfoskintigraf...

Research paper thumbnail of Kegemukan Dan Frekuensi Konsumsi Makanan Berlemak Yang Tinggi Merupakan Faktor Risiko Perlemakan Hati Pada Pasien Kanker Payudara Dengan Pemeriksaan Ultrasonografi Di Rumah Sakit Kanker Dharmais, Jakarta

Indonesian Journal of Cancer, 2015

Fatty liver is a term applied to wide spectrum of conditions characterized hispatologically by tr... more Fatty liver is a term applied to wide spectrum of conditions characterized hispatologically by trigliseride accumulation within the cytoplasm of hepatocytes which is examined using ultrasound. This study was aimed to identify the risk factors affecting fatty liver in the patients with breast cancer on ultrasound examination at Dharmais Cancer Hospital Jakarta. The design was a cross sectional study with 70 subjects, consisted of 37 fatty liver subjects and 33 normal subjects. The result showed that risk factors of fatty liver in patient with breast cancer were overweight and obesity (Body Mass Index ≥25 kg/m2) (OR : 5.5, 95%CI : 1.881 – 16.243) and high frequency of dietary fat (OR: 3.8, 95%CI : 1.084 – 13.445). ABSTRAK Perlemakan hati merupakan akumulasi asam lemak dalam bentuk trigliserida di dalam sitoplasma hepatosit yang diperiksa dengan menggunakan alat ultrasonografi.Tujuan penelitian ini adalah untuk mengetahui faktor risiko yang berpengaruh terhadap kejadian perlemakan hati...

Research paper thumbnail of Rumah Sakit Kanker Dharmais (Pusat Kanker Nasional): Melangkah Untuk Melaksanakan Program Penanggulangan Kanker Di Indonesia

Indonesian Journal of Cancer, 2008

Ketika anak terdiagnosis menderita kanker maka orangtua akan merasakan hal ini sebagai sesuatu ya... more Ketika anak terdiagnosis menderita kanker maka orangtua akan merasakan hal ini sebagai sesuatu yang mengejutkan dan pukulan yang berat, terutama bagi sang ibu, yang telah melahirkan dan umumnya menjadi pengasuh utama anak. Melalui penelitian ini, penulis membahas secara mendalam mengenai emosi-emosi yang dirasakan oleh ibu ditinjau dari teori Colin Murray Parkes. Parkes membagi emosi ke dalam empat fase yaitu: (a) shock, numbness, and disbelief; (b) acute distress, anger, and protest; (c) depression and despair; dan (d) acceptance and resolution. Dari penelitian didapatkan bahwa fase-fase tersebut timbul secara tidak berurutan dan berbeda untuk setiap individu. Perbedaan individu dipengaruhi oleh berbagai hal antara lain kepribadian subyek, dukungan sosial, kondisi fisik anak, dan prediksi yang dilakukan individu. Selain itu, reiigiusitas juga terbukti menjadi faktor penting untuk membantu ibu menerima Kenyataan yang harus dihadapi.

Research paper thumbnail of Telaah Awal Pemetaan Indikasi Pemeriksaan 18F-FDG PET/CT di RS Kanker "Dharmais" dengan Pedoman Appropriateness Criteria dari IAEA

Research paper thumbnail of A Qualitative Study: Early Detection of Breast Cancer in Indonesia (After Universal Health Coverage Implementation)

ObjectivesEarly detection is of vital importance in breast cancer management. BPJS Kesehatan, as ... more ObjectivesEarly detection is of vital importance in breast cancer management. BPJS Kesehatan, as Indonesia’s national health insurance, is expected to provide an adequate health service for breast cancer patients. This study aimed to obtain insight into the current conditions of health care services in Indonesia, related to early detection of breast cancer, particularly after BPJS Kesehatan implementation. MethodsThe study was conducted in 2017 in Yogyakarta, Indonesia with a wide range of socio-demographic backgrounds. Subjects comprised breast cancer patients and their relatives, health care professionals (HCPs), and healthy women from the general population who had no history of breast cancer and no family members with breast cancer. The subjects’ experiences and knowledge of health care services regarding early detection of breast cancer, were investigated through in-depth interviews. The thematic analysis guided the result synthesis from semi-structured in-depth interviews with...

Research paper thumbnail of An Asian Body to Tackle Cancers in Asia – The Asian National Cancer Centers Alliance

Asian Pacific Journal of Cancer Prevention

The socioeconomic burden of cancer is growing rapidly in the Asian region, with a concentrated bu... more The socioeconomic burden of cancer is growing rapidly in the Asian region, with a concentrated burden on low-and middle-income countries. The residents of this region, representing almost 60% of the global population, demonstrate an eclectic and complex nature, with huge disparities in ethnicity, sociocultural practices among others. The Asian National Cancer Centers Alliance (ANCCA) was established in 2005 by heads of several national cancer centers (NCCs) in the region to address common issues and concerns among Asian countries. During the first 13 years of ANCCA's existence, the participating NCCs' senior managers paved the way toward collaboration through transparent sharing of key facts and activities. Concrete achievements of the Alliance include the Asia Tobacco-Free Declaration, the establishment of the ANCCA Constitution in 2014 as well as the creation of an official website more recently. In November 2019, the most active ANCCA members (