Synexpression groups in eukaryotes (original) (raw)

NASA/ADS

Abstract

In 1960, Jacob and Monod described the bacterial operon, a cluster of functionally interacting genes whose expression is tightly coordinated. Global expression analysis has shown that the highly coordinate expression of genes functioning in common processes is also a widespread phenomenon in eukaryotes. These sets of co-regulated genes, or `synexpression groups', show a striking parallel to the operon, and may be a key determinant facilitating evolutionary change leading to animal diversity.

Publication:

Nature

Pub Date:

December 1999

DOI:

10.1038/990025

Bibcode:

1999Natur.402..483N