Burce Ozgen Mocan | University of Illinois at Chicago (original) (raw)
Papers by Burce Ozgen Mocan
American Journal of Ophthalmology Case Reports, 2022
International Journal of Radiation Oncology, Biology, Physics, 2017
N onacoustic cranial nerve schwannomas (NACNS), also termed nonvestibular schwannomas, are rare b... more N onacoustic cranial nerve schwannomas (NACNS), also termed nonvestibular schwannomas, are rare benign intracranial tumors that constitute fewer than 10% of schwannomas (23). The traditional treatment approach has consisted of surgical resection, including microsurgical techniques, with local control rates exceeding 80% (
Diagnostic and Interventional Radiology, 2021
Otology & Neurotology, 2016
Objective: To report the long-term outcomes of children who received auditory brainstem implant (... more Objective: To report the long-term outcomes of children who received auditory brainstem implant (ABI) because of severe inner ear malformations. Study Design: Retrospective chart review. Setting: Tertiary referral otolaryngology clinic. Subjects and Methods: Between July 2006 and October 2014, 60 children received ABI at Hacettepe University. Preoperative work up included otolaryngologic examination, audiological assessment, radiological evaluation together with assessment of language development and psychological status. The surgeries were performed via retrosigmoid approach with a pediatric neurosurgeon. Intraoperatively, electrical auditory brainstem response was utilized. Initial stimulation was done 4 to 5 weeks postoperatively. Outcomes were evaluated with Categories of Auditory Performance (CAP), speech intelligibility rate (SIR), functional auditory performance of cochlear implant (FAPCI) and Manchester Spoken Language Development Scale scores; receptive and expressive language ages were determined. Results: Sixty children who received ABI were between ages of 12 and 64 months. Thirty-five patients with follow up period of at least 1 year, were reported in means of longterm audiological and language results. The most prevelant inner ear malformation was cochlear hypoplasia (n ¼ 19). No major complication was encountered. Majority of the patients were in CAP 5 category, which implies that they can understand common phrases without lip reading. SIR was found out to be better with improving hearing thresholds. Children with ABI were performing worse than average cochlear implantation (CI) users when FAPCI scores were compared. Patients with the best hearing thresholds have expressive vocabulary of 50 to 200 words when evaluated with Manchester Spoken Language Development Scale. There was no relationship between the number of active electrodes and hearing thresholds. The type of inner ear anomaly with the best and the worst hearing thresholds were common cavity and cochlear aperture aplasia, respectively. Patients with additional handicaps had worse outcomes. Among 35 children, 29 had closed set discrimination and 12 developed open set discrimination above 50%. It was determined that, progress of the patients is faster in the initial 2 years when compared with further use of ABI. Conclusion: ABI is an acceptable and effective treatment modality for pediatric population with severe inner ear malformations. Bilateral stimulation together with CI and contralateral ABI should be utilized in suitable cases.
Otology & Neurotology, 2009
Poster: "ECR 2015 / C-2100 / Spinal imaging findings of mucopolysaccharidosis type VI" ... more Poster: "ECR 2015 / C-2100 / Spinal imaging findings of mucopolysaccharidosis type VI" by: "E. Bulut, B. Ozgen Mocan, H. S. Sivri; Ankara/TR"
Poster: "ECR 2015 / B-0581 / The evaluation of residual bone marrow signal changes in nasoph... more Poster: "ECR 2015 / B-0581 / The evaluation of residual bone marrow signal changes in nasopharyngeal carcinoma patients treated with radiation therapy" by: "Ş. Parlak, B. Ozgen Mocan, G. Yazici, A. Dolgun Barak; Ankara/TR"
Poster: "ECR 2011 / C-0785 / Significance of the cochlear aqueduct size and type in the deve... more Poster: "ECR 2011 / C-0785 / Significance of the cochlear aqueduct size and type in the development of postmeningitic sensorineural hearing loss" by: "B. Ozgen Mocan1, O. A. Ozmen2, A. Dolgun1, S. Sarac1, L. Sennaroglu1; 1Ankara/TR, 2Bursa/TR"
Cureus, 2016
Objectives: Evaluation of treatment results in patients with optic glioma and meningioma treated ... more Objectives: Evaluation of treatment results in patients with optic glioma and meningioma treated with fractionated stereotactic radiotherapy (FSRT). Methods: Twenty-five patients with optic glioma and meningioma who were treated with FSRT between July 2007 and September 2014 were retrospectively analyzed. All treatments were applied with CyberKnife® (Accuray Inc., Sunnyvale, CA, USA). Median age was 40 years (4-67 years). Twenty-one (84%) patients were female, and 4 (16%) were male. The diagnosis was glioma in 7 (28%), and meningioma in 18 (72%) patients, respectively, based on magnetic resonance imaging (MRI). The intracranial part of the optic nerve was invaded in 11 (44%) patients. Median tumor size was 21 mm (10-45 mm). Patients received a median dose of 22.5 Gy (20-25 Gy) FSRT in median 5 fractions (3-5). Maximum dose on plan was median 28.5 Gy (25-32 Gy) and the gross tumor volume (GTV) was median 4 cm3 (0.4-23 cm3). Mean doses of the ipsilateral eye, ipsilateral lens, ipsilat...
Poster: "ECR 2016 / C-1675 / Rhabdomyosarcoma everywhere: Differential diagnosis on Imaging&... more Poster: "ECR 2016 / C-1675 / Rhabdomyosarcoma everywhere: Differential diagnosis on Imaging" by: "A. Gunes, K. K. Oguz, B. Oguz, B. Ozgen Mocan, F. B. Ergen, U. Aydingoz, M. Haliloglu; Ankara/TR"
Poster: "ECR 2011 / C-1262 / Prevalance and relative frequencies of the congenital inner ear... more Poster: "ECR 2011 / C-1262 / Prevalance and relative frequencies of the congenital inner ear abnormalities in patients evaluated with temporal bone CT for sensorineural hearing loss" by: "B. Ozgen Mocan, E. Sanverdi, N. Orhan, S. Sarac, L. Sennaroglu; Ankara/TR"
PURPOSE To evaluate treatment results of stereotactic radiosurgery or fractionated stereotactic r... more PURPOSE To evaluate treatment results of stereotactic radiosurgery or fractionated stereotactic radiation therapy (SRS/FSRT) for uveal melanoma. METHODS AND MATERIALS We retrospectively evaluated 181 patients with 182 uveal melanomas receiving SRS/FSRT between 2007 and 2013. Treatment was administered with CyberKnife. RESULTS According to Collaborative Ocular Melanoma Study criteria, tumor size was small in 1%, medium in 49.5%, and large in 49.5% of the patients. Seventy-one tumors received <45 Gy, and 111 received ≥45 Gy. Median follow-up time was 24 months. Complete and partial response was observed in 8 and 104 eyes, respectively. The rate of 5-year overall survival was 98%, disease-free survival 57%, local recurrence-free survival 73%, distant metastasis-free survival 69%, and enucleation-free survival 73%. There was a significant correlation between tumor size and disease-free survival, SRS/FSRT dose and enucleation-free survival; and both were prognostic for local recurrenc...
Objectives: The aim of the present study is to evaluate the audiological, radiological, and etiol... more Objectives: The aim of the present study is to evaluate the audiological, radiological, and etiological in terms of clinical findings relating to babies and children with congenital unilateral hearing loss. Materials and Methods: Audiometric tests, tympanometric and acoustic reflex measurements, otoacoustic emission tests, and auditory brainstem response assessments were conducted. Twenty-nine babies and children (13 F ;16 M) diagnosed with congenital unilateral hearing loss, between the ages of 3–87 months, were included in this study. Results: Of these patients, 65.5% (n:19) were diagnosed with sensorineural hearing loss and 34.5% (n:10) with conductive hearing loss. Of the subjects with sensorineural hearing loss, 57.9% were diagnosed with profound hearing loss. Of the subjects with conductive hearing loss, 7 of the 10 (70%) had been diagnosed with microtia. Of the patients with conductive hearing loss, all those who had received CT scans were diagnosed with ossicular chain malfo...
Poster: "ECR 2015 / C-1312 / Notochord Derived “Pitfalls” of Central Skull Base " by: &... more Poster: "ECR 2015 / C-1312 / Notochord Derived “Pitfalls” of Central Skull Base " by: "E. Gumeler, O. Akca, B. Ozgen Mocan, K. Karli Oguz; Ankara/TR"
Neuroimaging Clinics of North America
Annals of Otology, Rhinology & Laryngology
Objectives: To present a systematic checklist to improve diagnosing otosclerosis (OS) on high-res... more Objectives: To present a systematic checklist to improve diagnosing otosclerosis (OS) on high-resolution computed tomography (HRCT) of the temporal bones and review this protocol’s efficacy in diagnosing OS on HRCT. Methods: A retrospective case series was performed at a University Referral Hospital in urban Chicago, Illinois. High-resolution computed tomographies of the temporal bone were reviewed including 17 ears in the test group with surgically confirmed OS and 21 ears in the control group surgically confirmed to not have OS. Preoperative HRCTs were evaluated by a single neuroradiologist using a systematic protocol created to assist in diagnosing OS. This looked for radiolucency at the fissula ante fenestram and pericochlear region, and new bone formation around the oval and round windows. Results: The radiologist accurately diagnosed OS in all 17 test group ears and ruled out OS in all 21 control group ears using the protocol. All 17 test ears were read to have lucency at the ...
Polish Journal of Radiology
A variety of conditions may affect the trigeminal nerve. Magnetic resonance imaging is the modali... more A variety of conditions may affect the trigeminal nerve. Magnetic resonance imaging is the modality of choice when trigeminal nerve pathology is suspected, and this modality plays an essential role in detecting causes. This review illustrates some of the pathological conditions relevant to the trigeminal nerve in magnetic resonance imaging.
American Journal of Ophthalmology Case Reports, 2022
International Journal of Radiation Oncology, Biology, Physics, 2017
N onacoustic cranial nerve schwannomas (NACNS), also termed nonvestibular schwannomas, are rare b... more N onacoustic cranial nerve schwannomas (NACNS), also termed nonvestibular schwannomas, are rare benign intracranial tumors that constitute fewer than 10% of schwannomas (23). The traditional treatment approach has consisted of surgical resection, including microsurgical techniques, with local control rates exceeding 80% (
Diagnostic and Interventional Radiology, 2021
Otology & Neurotology, 2016
Objective: To report the long-term outcomes of children who received auditory brainstem implant (... more Objective: To report the long-term outcomes of children who received auditory brainstem implant (ABI) because of severe inner ear malformations. Study Design: Retrospective chart review. Setting: Tertiary referral otolaryngology clinic. Subjects and Methods: Between July 2006 and October 2014, 60 children received ABI at Hacettepe University. Preoperative work up included otolaryngologic examination, audiological assessment, radiological evaluation together with assessment of language development and psychological status. The surgeries were performed via retrosigmoid approach with a pediatric neurosurgeon. Intraoperatively, electrical auditory brainstem response was utilized. Initial stimulation was done 4 to 5 weeks postoperatively. Outcomes were evaluated with Categories of Auditory Performance (CAP), speech intelligibility rate (SIR), functional auditory performance of cochlear implant (FAPCI) and Manchester Spoken Language Development Scale scores; receptive and expressive language ages were determined. Results: Sixty children who received ABI were between ages of 12 and 64 months. Thirty-five patients with follow up period of at least 1 year, were reported in means of longterm audiological and language results. The most prevelant inner ear malformation was cochlear hypoplasia (n ¼ 19). No major complication was encountered. Majority of the patients were in CAP 5 category, which implies that they can understand common phrases without lip reading. SIR was found out to be better with improving hearing thresholds. Children with ABI were performing worse than average cochlear implantation (CI) users when FAPCI scores were compared. Patients with the best hearing thresholds have expressive vocabulary of 50 to 200 words when evaluated with Manchester Spoken Language Development Scale. There was no relationship between the number of active electrodes and hearing thresholds. The type of inner ear anomaly with the best and the worst hearing thresholds were common cavity and cochlear aperture aplasia, respectively. Patients with additional handicaps had worse outcomes. Among 35 children, 29 had closed set discrimination and 12 developed open set discrimination above 50%. It was determined that, progress of the patients is faster in the initial 2 years when compared with further use of ABI. Conclusion: ABI is an acceptable and effective treatment modality for pediatric population with severe inner ear malformations. Bilateral stimulation together with CI and contralateral ABI should be utilized in suitable cases.
Otology & Neurotology, 2009
Poster: "ECR 2015 / C-2100 / Spinal imaging findings of mucopolysaccharidosis type VI" ... more Poster: "ECR 2015 / C-2100 / Spinal imaging findings of mucopolysaccharidosis type VI" by: "E. Bulut, B. Ozgen Mocan, H. S. Sivri; Ankara/TR"
Poster: "ECR 2015 / B-0581 / The evaluation of residual bone marrow signal changes in nasoph... more Poster: "ECR 2015 / B-0581 / The evaluation of residual bone marrow signal changes in nasopharyngeal carcinoma patients treated with radiation therapy" by: "Ş. Parlak, B. Ozgen Mocan, G. Yazici, A. Dolgun Barak; Ankara/TR"
Poster: "ECR 2011 / C-0785 / Significance of the cochlear aqueduct size and type in the deve... more Poster: "ECR 2011 / C-0785 / Significance of the cochlear aqueduct size and type in the development of postmeningitic sensorineural hearing loss" by: "B. Ozgen Mocan1, O. A. Ozmen2, A. Dolgun1, S. Sarac1, L. Sennaroglu1; 1Ankara/TR, 2Bursa/TR"
Cureus, 2016
Objectives: Evaluation of treatment results in patients with optic glioma and meningioma treated ... more Objectives: Evaluation of treatment results in patients with optic glioma and meningioma treated with fractionated stereotactic radiotherapy (FSRT). Methods: Twenty-five patients with optic glioma and meningioma who were treated with FSRT between July 2007 and September 2014 were retrospectively analyzed. All treatments were applied with CyberKnife® (Accuray Inc., Sunnyvale, CA, USA). Median age was 40 years (4-67 years). Twenty-one (84%) patients were female, and 4 (16%) were male. The diagnosis was glioma in 7 (28%), and meningioma in 18 (72%) patients, respectively, based on magnetic resonance imaging (MRI). The intracranial part of the optic nerve was invaded in 11 (44%) patients. Median tumor size was 21 mm (10-45 mm). Patients received a median dose of 22.5 Gy (20-25 Gy) FSRT in median 5 fractions (3-5). Maximum dose on plan was median 28.5 Gy (25-32 Gy) and the gross tumor volume (GTV) was median 4 cm3 (0.4-23 cm3). Mean doses of the ipsilateral eye, ipsilateral lens, ipsilat...
Poster: "ECR 2016 / C-1675 / Rhabdomyosarcoma everywhere: Differential diagnosis on Imaging&... more Poster: "ECR 2016 / C-1675 / Rhabdomyosarcoma everywhere: Differential diagnosis on Imaging" by: "A. Gunes, K. K. Oguz, B. Oguz, B. Ozgen Mocan, F. B. Ergen, U. Aydingoz, M. Haliloglu; Ankara/TR"
Poster: "ECR 2011 / C-1262 / Prevalance and relative frequencies of the congenital inner ear... more Poster: "ECR 2011 / C-1262 / Prevalance and relative frequencies of the congenital inner ear abnormalities in patients evaluated with temporal bone CT for sensorineural hearing loss" by: "B. Ozgen Mocan, E. Sanverdi, N. Orhan, S. Sarac, L. Sennaroglu; Ankara/TR"
PURPOSE To evaluate treatment results of stereotactic radiosurgery or fractionated stereotactic r... more PURPOSE To evaluate treatment results of stereotactic radiosurgery or fractionated stereotactic radiation therapy (SRS/FSRT) for uveal melanoma. METHODS AND MATERIALS We retrospectively evaluated 181 patients with 182 uveal melanomas receiving SRS/FSRT between 2007 and 2013. Treatment was administered with CyberKnife. RESULTS According to Collaborative Ocular Melanoma Study criteria, tumor size was small in 1%, medium in 49.5%, and large in 49.5% of the patients. Seventy-one tumors received <45 Gy, and 111 received ≥45 Gy. Median follow-up time was 24 months. Complete and partial response was observed in 8 and 104 eyes, respectively. The rate of 5-year overall survival was 98%, disease-free survival 57%, local recurrence-free survival 73%, distant metastasis-free survival 69%, and enucleation-free survival 73%. There was a significant correlation between tumor size and disease-free survival, SRS/FSRT dose and enucleation-free survival; and both were prognostic for local recurrenc...
Objectives: The aim of the present study is to evaluate the audiological, radiological, and etiol... more Objectives: The aim of the present study is to evaluate the audiological, radiological, and etiological in terms of clinical findings relating to babies and children with congenital unilateral hearing loss. Materials and Methods: Audiometric tests, tympanometric and acoustic reflex measurements, otoacoustic emission tests, and auditory brainstem response assessments were conducted. Twenty-nine babies and children (13 F ;16 M) diagnosed with congenital unilateral hearing loss, between the ages of 3–87 months, were included in this study. Results: Of these patients, 65.5% (n:19) were diagnosed with sensorineural hearing loss and 34.5% (n:10) with conductive hearing loss. Of the subjects with sensorineural hearing loss, 57.9% were diagnosed with profound hearing loss. Of the subjects with conductive hearing loss, 7 of the 10 (70%) had been diagnosed with microtia. Of the patients with conductive hearing loss, all those who had received CT scans were diagnosed with ossicular chain malfo...
Poster: "ECR 2015 / C-1312 / Notochord Derived “Pitfalls” of Central Skull Base " by: &... more Poster: "ECR 2015 / C-1312 / Notochord Derived “Pitfalls” of Central Skull Base " by: "E. Gumeler, O. Akca, B. Ozgen Mocan, K. Karli Oguz; Ankara/TR"
Neuroimaging Clinics of North America
Annals of Otology, Rhinology & Laryngology
Objectives: To present a systematic checklist to improve diagnosing otosclerosis (OS) on high-res... more Objectives: To present a systematic checklist to improve diagnosing otosclerosis (OS) on high-resolution computed tomography (HRCT) of the temporal bones and review this protocol’s efficacy in diagnosing OS on HRCT. Methods: A retrospective case series was performed at a University Referral Hospital in urban Chicago, Illinois. High-resolution computed tomographies of the temporal bone were reviewed including 17 ears in the test group with surgically confirmed OS and 21 ears in the control group surgically confirmed to not have OS. Preoperative HRCTs were evaluated by a single neuroradiologist using a systematic protocol created to assist in diagnosing OS. This looked for radiolucency at the fissula ante fenestram and pericochlear region, and new bone formation around the oval and round windows. Results: The radiologist accurately diagnosed OS in all 17 test group ears and ruled out OS in all 21 control group ears using the protocol. All 17 test ears were read to have lucency at the ...
Polish Journal of Radiology
A variety of conditions may affect the trigeminal nerve. Magnetic resonance imaging is the modali... more A variety of conditions may affect the trigeminal nerve. Magnetic resonance imaging is the modality of choice when trigeminal nerve pathology is suspected, and this modality plays an essential role in detecting causes. This review illustrates some of the pathological conditions relevant to the trigeminal nerve in magnetic resonance imaging.