Mahanem Noor | Universiti Kebangsaan Malaysia (original) (raw)

Papers by Mahanem Noor

DOAJ (DOAJ: Directory of Open Access Journals), 2004

Mahanem Mat Noor et al. 54 data, aphrodisiac and sperm quality analysis, can be used to further s... more Mahanem Mat Noor et al. 54 data, aphrodisiac and sperm quality analysis, can be used to further strengthen our belief that E. longifolia root extract can be used to enhance the male reproductive system. METHODS Animals Adult Sprague-Dawley male rats (250350 gram), fed ...

Education and Information Technologies, May 25, 2023

Environment-Behaviour Proceedings Journal

The aim of conducting this research is to examine the influence of social media engagement on inf... more The aim of conducting this research is to examine the influence of social media engagement on information-seeking behavior. There is lack of concern about generalizability and implementation towards emphasizing the effects of social media engagement on information-seeking behavior in Malaysia. A close-ended questionnaire was distributed to the students to conduct the data collection for this research. The data was collected from students and was analyzed using SPSS version 26. Findings show that two hypotheses were accepted; Novelty and Perceived Usability have a positive and significant relationship between information-seeking behavior, while Focus Attention and aesthetics were found insignificant for information-seeking behavior. Keywords: Social media, information-seeking behavior, Social media engagement, aesthetic, education eISSN: 2398-4287 © 2022. The Authors. Published for AMER ABRA cE-Bs by E-International Publishing House, Ltd., UK. This is an open-access article under th...

Medicinal and Aromatic plants, Nov 3, 2017

Background: The present investigation was conducted to study the antibacterial effect of aqueous,... more Background: The present investigation was conducted to study the antibacterial effect of aqueous, ethanolic and ethyl acetate extracts of Teucrium polium plant on the bacteria isolated from urine samples of those with UTI and to compare it with the effect of commonly used antibiotics in treating UTIs. Materials and Methods: The antibiotic resistance of 147 strains of bacteria causing UTIs to the antibiotics selected through Kirby-Bauer disk diffusion method was determined. In the meantime, the aqueous, ethanolic and ethyl acetate extracts of T. polium plant were prepared. The antibacterial activity of these extracts was examined using Disk Diffusion Method. Finally, Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of antibacterial were determined using serial dilution method. Results: T. polium extracts were merely effective in enterococcus and pseudomonas bacteria. In general, the MIC rate of aqueous extract in enterococcus was 1.25-5 mg/ml. The MIC rate of ethanolic extract for enterococcus was calculated as 10 mg/ml. The MIC of aqueous and ethyl acetate extracts for pseudomonas bacteria were achieved as 5 and 20 mg/ml, respectively. The MBC contents of aqueous and ethyl acetate extracts of teucrium for pseudomonas bacteria was 10 mg/ml in aqueous and 20 mg/ml in ethyl acetate extracts. The MBC content of extracts for enterococcus bacteria were 10 mg/ml in aqueous extract and 20 mg/ml in ethanolic extract. Conclusion: T. polium extract can be effective in some bacteria causing urinary tract infection, especially enterococcus.

Medicinal & Aromatic Plants, 2017

Australian journal of basic and applied sciences, 2011

The present study was conducted to observe the beneficial effect of goat milk on the sperm parame... more The present study was conducted to observe the beneficial effect of goat milk on the sperm parameters of nicotine treated rats. Sprague Dawley juvenile rats (5 to 6 weeks old) were randomly divided into three groups. For nicotine (N) and goat milk (GM) groups, the rats were daily injected with 5.0mg/kg body weight of nicotine and force-fed with 20.0ml/kg body weight of goat milk, respectively. However, for nicotine with goat milk (N-GM) group, the rats were injected with 5.0mg/kg body weight of nicotine and force-fed with 20.0ml/kg body weight of goat milk. After 60 days of treatments, the rats were sacrificed and the reproductive organs were removed. Sperm were collected from epididymis and assessed for sperm count, viability and morphology. Goat milk (GM) group showed higher sperm count (40.30±13.39 x 10 5 /ml), more live sperm (385.49±12.97) and more normal sperm (188.31±0.61) than N and N-GM groups (P<0.05). However, co-administration of nicotine with goat milk (N-GM) gave hi...

Pertanika J. Trop. …, 2010

The beef industry prefers male calves as they tend to have higher growth rates and feed efficienc... more The beef industry prefers male calves as they tend to have higher growth rates and feed efficiency for meat production. The dairy industry, however, prefers female calves which produce offspring and milk for dairy products. Thus, methods are required to determine ...

Malaysian applied biology, Nov 30, 2021

Moringa oleifera leaves were essential for lowering blood glucose levels and increasing androgen ... more Moringa oleifera leaves were essential for lowering blood glucose levels and increasing androgen levels. This study evaluates the antihyperglycemic properties of Moringa oleifera (MO) leaves aqueous extract and its effect on diabetes-induced male Sprague Dawley rats in attenuating sexual dysfunction. A total of 40 mature male rats were divided into four main groups which were normal control group that received 1 mL of distilled water, the negative control group which did not receive any treatment, positive control group that received 500 mg/kg body weight of metformin, and MO treated group that received 400 mg/kg body weight of Moringa oleifera leaves aqueous extract. All groups were analyzed after 14 and 21 days for their fasting blood glucose level (FBGL) and sexual behavior (mounting latency and mounting frequency). Analysis of testosterone level was also conducted using the testosterone kit of enzyme-linked immunosorbent assay (ELISA). The data of the treatment group were compared to the control group subjected to one-way ANOVA using IBM SPSS Statistics 22 analysis. The FBGL of diabetes-induced rats treated with Moringa oleifera leaves aqueous extract significantly decreased (p<0.05) and the plasma testosterone level increased (p<0.05) compared to the negative and positive control groups. Diabetesinduced rats treated with Moringa oleifera leaves aqueous extract also showed a significant decrease (p<0.05) in mounting latency and increase (p<0.05) in mounting frequency within 15 min of the observation period. This study demonstrated that Moringa oleifera leaves aqueous extract could reduce FBGL significantly and improve the sexual dysfunction of diabetesinduced male rats.

Toxics

Xanthone is an organic compound mostly found in mangosteen pericarp and widely known for its anti... more Xanthone is an organic compound mostly found in mangosteen pericarp and widely known for its anti-proliferating effect on cancer cells. In this study, we evaluated the effects of xanthone crude extract (XCE) and α-mangostin (α-MG) on normoxic and hypoxic human hepatocellular carcinoma (HepG2) cells and their toxicity towards zebrafish embryos. XCE was isolated using a mixture of acetone and water (80:20) and verified via high performance liquid chromatography (HPLC). Both XCE and α-MG showed higher anti-proliferation effects on normoxic HepG2 cells compared to the control drug, 5-fluorouracil (IC50 = 50.23 ± 1.38, 8.39 ± 0.14, and 143.75 ± 15.31 μg/mL, respectively). In hypoxic conditions, HepG2 cells were two times less sensitive towards XCE compared to normoxic HepG2 cells (IC50 = 109.38 ± 1.80 μg/mL) and three times less sensitive when treated with >500 μg/mL 5-fluorouracil (5-FU). A similar trend was seen with the α-MG treatment on hypoxic HepG2 cells (IC50 = 10.11 ± 0.05 μg/...

International Journal of Emerging Technologies in Learning (iJET)

The boost of mobile devices and internet technologies has led to the development of new content g... more The boost of mobile devices and internet technologies has led to the development of new content geared to enhance the learning experience of students while simultaneously ensuring the economizing of the teacher’s time. The era of industrial revolution 4.0 transformed many aspects of life including the basic approaches towards teaching and learning. The needs and demands of students and teachers are changing in line with the revolution of emerging technologies. However, even with the advent of technology, STEM subjects are yet to fully grasp the attention of students. Learning especially in secondary schools and higher education intuitions needs to be redesigned to improve students' learning experience, especially in STEM subjects which involve complex concepts and processes that are difficult to visualize and require students to be fully engaged. Accordingly, this paper discusses the design and development of a learning experience model aimed at improving the teaching of Biology...

Biology, Medicine, & Natural Product Chemistry, 2021

Assesment of rat sperm motility can be carried out on sperm sample from epididimal source using m... more Assesment of rat sperm motility can be carried out on sperm sample from epididimal source using minimal amount of equipment. This method will aid researcher and practitioner working in the field of sperm quality to determined rat sperm motility rapidly and efficiently.

American Journal of Physiology-Endocrinology and Metabolism, 2021

The high-fat diet utilized in the present study induced obesity in the male rats. Bee bread suppl... more The high-fat diet utilized in the present study induced obesity in the male rats. Bee bread supplementation mitigated impaired steroidogenesis, spermatogenesis, mating behavior, and fertility potential by counteracting the downregulation of steroidogenic genes, thus increasing testosterone levels and suppressing epididymal oxidative stress. These benefits may be due to the abundance of phenolic and flavonoid compounds in bee bread.

Sains Malaysiana, 2017

Gynura procumbens (GP) has been widely used in traditional medicine due to its ability in treatin... more Gynura procumbens (GP) has been widely used in traditional medicine due to its ability in treating various types of diseases. This study was carried out to determine the effects of GP on blood glucose level, fertility and libido of streptozotocin-induced male rats. A total of 42 male rats were randomly sorted into six groups; normal, negative and positive controls and three treated groups with different dosages of GP aqueous extract (GPAE); 150, 300 and 450 mg/kg. Each group was treated via oral feeding for 14 consecutive days. The rats were sacrificed on day 15 for further analysis. Administration of GPAE significantly lowered the fasting blood glucose (FBG) level and increased the plasma testosterone level of diabetic-induced rats compared to the positive and negative control groups. There was also a significant increase in the sperm quality as well as the fertility of GPAE treated groups compared to the negative and positive control groups. Sexual behaviour analysis demonstrated that GPAE is able to facilitate the expression of sexual behaviour significantly; increased mounting frequency and reduced mounting latency. These lines of evidence suggested that GPAE can act as antihyperglycaemic, profertility and libido agents. However, its mechanism(s) remains unresolved.

Malaysian applied biology, 2016

Boletus qriseipurpureus (gelam mushroom) is a mushroom used by locals in Tok Bali, Kelantan, Mala... more Boletus qriseipurpureus (gelam mushroom) is a mushroom used by locals in Tok Bali, Kelantan, Malaysia to treat diabetes, cervical cancer and breast cancer. The active compounds in B. qriseipurpureus remain unidentified. Therefore, in this study, we investigated the potential medicinal properties of B. qriseipurpureus extracts (hot water, cold water and methanol extracts) by conducting preliminary phytochemical screening, in vitro antioxidant, in vitro antiproliferative and in vivo antidiabetic test. Biochemical assays were performed to detect the presence of alkaloids, anthraquinones, flavonoids, reducing sugars, saponins, steroids and tannins in B. qriseipurpureus extracts. 1,1-diphenyl-2-picrylhydrazyl (DPPH) was used to evaluate the antioxidant capacity of B. qriseipurpureus extracts, while MTT cell proliferation assay (3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide) was used to investigate the extracts antiproliferative activity. The effects of B. qriseipurpureus ex...

Mini-Reviews in Medicinal Chemistry, 2020

It is expected that in 2050, there will be more than 20% of senior citizens aged over 60 years wo... more It is expected that in 2050, there will be more than 20% of senior citizens aged over 60 years worldwide. Such alarming statistics require immediate attention to improve the health of the aging population. Since aging is closely related to the loss of antioxidant defense mechanisms, this situation eventually leads to numerous health problems, including fertility reduction. Furthermore, plant extracts have been used in traditional medicine as potent antioxidant sources. Although many experiments had reported the impact of various bioactive compounds on aging or fertility, there is a lack of review papers that combine both subjects. In this review, we have collected and discussed various bioactive compounds from 26 different plant species known to affect both longevity and fertility. These compounds, including phenolics and terpenes, are mostly involved in the antioxidant defense mechanisms of diverse organisms such as rats, mites, fruit flies, roundworms, and even roosters. A human c...

This study was conducted to gauge students’ competency and satisfaction in employment preparation... more This study was conducted to gauge students’ competency and satisfaction in employment preparation within programmes offered by the School of Biosciences and Biotechnology, at the Faculty of Science and Technology, Universiti Kebangsaan Malaysia (UKM). A survey questionnaire was distributed to all final year students of the School and 128 of them responded. The results showed that for the programme components, respondents were most satisfied with the quality of academic staff, followed by the quality of fellow students, curricular contents and overall learning environment. In terms of knowledge, general skills, and virtues they received, the respondents expressed high competency levels in various areas which include the languages, English and Bahasa Melayu, interpersonal skills, information technology and research skills, and work related skills gained through industrial training attachment. However, respondents rated the overall academic experience to be of average standing. These f...

Asian Pacific Journal of Reproduction, 2019

Objective: To study the effects of co-administration of Gynura procumbens (GP) and kelulut honey ... more Objective: To study the effects of co-administration of Gynura procumbens (GP) and kelulut honey (KH) on male fertility and libido in diabetes-induced rats. Methods: A total 42 males Sprague Dawley rats aged 8 weeks were randomly and equally divided into six different groups. All groups except a normal control group were induced with 50 mg/kg of streptozotocin (STZ) intravenously to induce diabetes. A positive control group was treated with an antidiabetic drug, metformin (500 mg/kg) whereas a negative control group remained untreated throughout the experiment. Meanwhile, another three treatments on diabetic rat groups were performed and categorised as Group 1 (450 mg/kg GP + 300 mg/kg KH), Group 2 (450 mg/kg GP + 600 mg/kg KH) and Group 3 (450 mg/kg GP + 1 200 mg/kg KH). Treatments were given for seven consecutive days through oral gavage and all rats were euthanized on day 8th for fasting blood glucose analysis, sperm quality, spermatogenesis, sexual behaviour and implantation sit...