Claude Tomberg | Université libre de Bruxelles (original) (raw)

Papers by Claude Tomberg

Research paper thumbnail of Méthode d'identification chez l'homme d'une activité cérébrale de nature cognitive dans la réponse électrique non moyennée dérivée du cuir chevelu

Bulletin de la Classe des sciences. Académie royale de Belgique, 1993

Pour pouvoir étudier non-invasivement chez l'homme l'enregistrement non moyenné de potent... more Pour pouvoir étudier non-invasivement chez l'homme l'enregistrement non moyenné de potentiels cérébraux à un stimulus sensoriel, il faut dis¬ poser de critères permettant de valider les résultats en maîtrisant les interférences dues aux bruits instrumentaux ou physiologiques. Nous avons tiré parti de la latéralisation de la réponse cognitive P40 au cuir chevelu pariétal du côté opposé à la main stimulée pour déceler, dans la réponse non moyennée, la présence d'une positivité aux latences définies dans nos travaux antérieurs. La cartographie topographique de réponses cérébrales non moyennées apporte une méthodologie nouvelle pour valider les réponses cognitives précoces.

Research paper thumbnail of Oscillations à 40Hz du potentiel électrique de neurones cérébraux chez l 'homme et leur signification fonctionnelle

Bulletin de la Classe des sciences. Académie royale de Belgique, 1993

L'utilisation d'un logiciel pour le filtrage numérique de la bande de 35 à 45 Hz nous a p... more L'utilisation d'un logiciel pour le filtrage numérique de la bande de 35 à 45 Hz nous a permis d'analyser les oscillations électriques cérébrales dites gamma dérivées non-invasivement chez l'Homme. La méthode a été validée par la cohérence du profil de la transformée de Fourier pour cette bande de fréquences. Les oscillations à environ 40 Hz apparaissent de manière quasi ininterrompue sur la convexité du cerveau et elles correspondent à un certain niveau de vigilance de l'encéphale. De plus, nous montrons que des liaisons fonctionnelles de nature électrolphysiologique, avec mise en phase transitoire de certaines aires du cerveau à 40 Hz, sont mises en jeu pour l'élaboration cognitive d'un message sensoriel.

Research paper thumbnail of Horses (Equus caballus) facial micro-expressions: insight into discreet social information

Scientific Reports, May 27, 2023

Research paper thumbnail of L'intention de réaliser un mouvement volontaire prépare de manière sélective les aires corticales motrices du muscle «prime mover»

Bulletin de la Classe des sciences. Académie royale de Belgique, 1993

La stimulation transcortical magnétique est une méthode non invasive permettant d'analyser ch... more La stimulation transcortical magnétique est une méthode non invasive permettant d'analyser chez l'Homme l'excitabilité des centres moteurs corticaux. Nous utilisons un paradigme de temps de réaction où le sujet réagit par un mouvement des doigts de la main à un signal sensoriel, et nous appliquons une stimulation magnétique légèrement supraliminaire juste avant la réponse volontaire du sujet. Nous montrons ainsi des effets facilitateurs ou inhibiteurs sélectifs qui s'exercent synaptiquement sur les motoneurones des muscles considérés et qui reflètent l'intention motrice du sujet.

Research paper thumbnail of Alcohol Pathophysiology

Journal of Psychophysiology, 2010

There is no specialized alcohol addiction area in the brain; rather, alcohol acts on a wide range... more There is no specialized alcohol addiction area in the brain; rather, alcohol acts on a wide range of excitatory and inhibitory nervous networks to modulate neurotransmitters actions by binding with and altering the function of specific proteins. With no hemato-encephalic barrier for alcohol, its actions are strongly related to the amount of intake. Heavy alcohol intake is associated with both structural and functional changes in the central nervous system with long-term neuronal adaptive changes contributing to the phenomena of tolerance and withdrawal. The effects of alcohol on the function of neuronal networks are heterogeneous. Because ethanol affects neural activity in some brain sites but is without effect in others, its actions are analyzed in terms of integrated connectivities in the functional circuitry of neuronal networks, which are of particular interest because of the cognitive interactions discussed in the manuscripts contributing to this review. Recent molecular data are reviewed as a support for the other contributions dealing with cognitive disturbances related to alcohol acute and addicted consumption.

Research paper thumbnail of Mécanismes neurophysiologiques mis en jeu dans des temps de réaction simple

Research paper thumbnail of Stages of Somatosensory Processing Revealed by Mapping Event-Related Potentials

Adapted behaviour requires the selective processing of the stream of sensory stimuli impinging on... more Adapted behaviour requires the selective processing of the stream of sensory stimuli impinging on the sense organs so that distinct sensory inputs become integrated into current cognition. The perceptual evaluation of inputs involves both parallel and serial brain mechanisms whose complexity must be appreciated when designing experimental paradigms.

Research paper thumbnail of Alcohol and Its Impact on Motor Control

Journal of Psychophysiology, 2010

Acute and chronic alcohol intoxications have particularly deleterious consequences on physiologic... more Acute and chronic alcohol intoxications have particularly deleterious consequences on physiological processes involving motor control and balance. This paper describes alcohol impairments to the central motor system networks in social and heavy drinkers and in individuals dependent on alcohol with or without neurological diseases.

Research paper thumbnail of The search for 'neutral' conditions for recording control event-related potentials in order to assess cognitive components to both irrelevant and relevant stimuli: evidence for short-latency cognitive somatosensory effects

Research paper thumbnail of Focal enhancement of chaotic strange attractor dimension in the left semantic (Wernicke) human cortex during reading without concomitant change in vigilance level

Neuroscience Letters, Mar 1, 1999

Research paper thumbnail of Rapport de la 2e Journée scientifique de la plateforme belge des méthodes alternatives à l'expérimentation animale. Fondation Prince Laurent

Bulletins de l'Académie Royale de Belgique, 2004

Tomberg Claude. Rapport de la 2e Journée scientifique de la plateforme belge des méthodes alterna... more Tomberg Claude. Rapport de la 2e Journée scientifique de la plateforme belge des méthodes alternatives à l'expérimentation animale. Fondation Prince Laurent.. In: Bulletin de la Classe des sciences, tome 15, n°1-6, 2004. pp. 77-80

Research paper thumbnail of PS-24-10 Is the ability to reach a high level in the motor program selectivity related to the mode of the daily manipulatory activities?

Electroencephalography and clinical neurophysiology, Sep 1, 1995

Research paper thumbnail of Categories of Alcohol Consumers

Journal of Psychophysiology, 2010

Common patterns of alcohol consumption are described with their main criteria, blood alcohol leve... more Common patterns of alcohol consumption are described with their main criteria, blood alcohol levels, and diagnostic criteria. Binge drinking, an acute alcohol intoxication pattern of particularly concern, is also described, as it appears to be the most common pattern among teenagers when the brain is not yet mature. A number of classification schemes have been proposed specially for social drinking and alcohol dependence, and discussions still surround about them. The article summarize a consensus in classification.

Research paper thumbnail of Failure to recognise objects by active touch (astereognosia) results from lesion of parietalcortex representation of finger kinaesthesis

The Lancet, Jul 1, 1999

The inability to identify objects by manipulation with eyes closed (astereognosia) results from a... more The inability to identify objects by manipulation with eyes closed (astereognosia) results from a focal cortical lesion of the second order parietal area 2, which integrates inputs from finger joints with tactile information.

Research paper thumbnail of Non-averaged human brain potentials in somatic attention: the short-latency cognition-related P40 component

The Journal of Physiology, Oct 15, 1996

Research paper thumbnail of Inadequacy of the average reference for the topographic mapping of focal enhancements of brain potentials

Clinical Neurophysiology, Jul 1, 1990

Research paper thumbnail of Nasopharyngeal recordings of somatosensory evoked potentials document the medullary origin of the N18 far-field

Clinical Neurophysiology, Nov 1, 1991

Because the nasopharyngeal électrode provides non-invasive access to the ventral brain-stem at th... more Because the nasopharyngeal électrode provides non-invasive access to the ventral brain-stem at the medullo-pontine level we used it for recording somatosensory evoked potentials (SEPs) to médian nerve stimulation (non-cephalic référence). After the P9 and Pli far-fields, the nasopharyngeal SEPs disclosed a negative-going component which was interpreted as the near-field équivalent of the P14 scalp far-field generated in the caudal part of the medial lemniscus. Nasopharyngeal SEPs also revealed a large N18 with voltage and features strikingly similar to those of the scalp-recorded N18 far-field. Thèse results suggest that N18 is generated in the medulla and not more rostrally in the brain-stem. The use of a nasopharyngeal électrode as référence for topographie brain mapping is discussed. The paper documents the feasibility and relevance of nasopharyngeal recordings for non-invasive analysis of short-latency SEPs.

Research paper thumbnail of The point correlation dimension: Performance with nonstationary surrogate data and noise

Integrative Physiological and Behavioral Science, Jul 1, 1994

Research paper thumbnail of P300 and conscious perception

Clinical Neurophysiology, 2005

info:eu-repo/semantics/publishe

Research paper thumbnail of Bit-mapping of cognitive somatosensory potentials

Electroencephalography and Clinical Neurophysiology, 1990

Research paper thumbnail of Méthode d'identification chez l'homme d'une activité cérébrale de nature cognitive dans la réponse électrique non moyennée dérivée du cuir chevelu

Bulletin de la Classe des sciences. Académie royale de Belgique, 1993

Pour pouvoir étudier non-invasivement chez l'homme l'enregistrement non moyenné de potent... more Pour pouvoir étudier non-invasivement chez l'homme l'enregistrement non moyenné de potentiels cérébraux à un stimulus sensoriel, il faut dis¬ poser de critères permettant de valider les résultats en maîtrisant les interférences dues aux bruits instrumentaux ou physiologiques. Nous avons tiré parti de la latéralisation de la réponse cognitive P40 au cuir chevelu pariétal du côté opposé à la main stimulée pour déceler, dans la réponse non moyennée, la présence d'une positivité aux latences définies dans nos travaux antérieurs. La cartographie topographique de réponses cérébrales non moyennées apporte une méthodologie nouvelle pour valider les réponses cognitives précoces.

Research paper thumbnail of Oscillations à 40Hz du potentiel électrique de neurones cérébraux chez l 'homme et leur signification fonctionnelle

Bulletin de la Classe des sciences. Académie royale de Belgique, 1993

L'utilisation d'un logiciel pour le filtrage numérique de la bande de 35 à 45 Hz nous a p... more L'utilisation d'un logiciel pour le filtrage numérique de la bande de 35 à 45 Hz nous a permis d'analyser les oscillations électriques cérébrales dites gamma dérivées non-invasivement chez l'Homme. La méthode a été validée par la cohérence du profil de la transformée de Fourier pour cette bande de fréquences. Les oscillations à environ 40 Hz apparaissent de manière quasi ininterrompue sur la convexité du cerveau et elles correspondent à un certain niveau de vigilance de l'encéphale. De plus, nous montrons que des liaisons fonctionnelles de nature électrolphysiologique, avec mise en phase transitoire de certaines aires du cerveau à 40 Hz, sont mises en jeu pour l'élaboration cognitive d'un message sensoriel.

Research paper thumbnail of Horses (Equus caballus) facial micro-expressions: insight into discreet social information

Scientific Reports, May 27, 2023

Research paper thumbnail of L'intention de réaliser un mouvement volontaire prépare de manière sélective les aires corticales motrices du muscle «prime mover»

Bulletin de la Classe des sciences. Académie royale de Belgique, 1993

La stimulation transcortical magnétique est une méthode non invasive permettant d'analyser ch... more La stimulation transcortical magnétique est une méthode non invasive permettant d'analyser chez l'Homme l'excitabilité des centres moteurs corticaux. Nous utilisons un paradigme de temps de réaction où le sujet réagit par un mouvement des doigts de la main à un signal sensoriel, et nous appliquons une stimulation magnétique légèrement supraliminaire juste avant la réponse volontaire du sujet. Nous montrons ainsi des effets facilitateurs ou inhibiteurs sélectifs qui s'exercent synaptiquement sur les motoneurones des muscles considérés et qui reflètent l'intention motrice du sujet.

Research paper thumbnail of Alcohol Pathophysiology

Journal of Psychophysiology, 2010

There is no specialized alcohol addiction area in the brain; rather, alcohol acts on a wide range... more There is no specialized alcohol addiction area in the brain; rather, alcohol acts on a wide range of excitatory and inhibitory nervous networks to modulate neurotransmitters actions by binding with and altering the function of specific proteins. With no hemato-encephalic barrier for alcohol, its actions are strongly related to the amount of intake. Heavy alcohol intake is associated with both structural and functional changes in the central nervous system with long-term neuronal adaptive changes contributing to the phenomena of tolerance and withdrawal. The effects of alcohol on the function of neuronal networks are heterogeneous. Because ethanol affects neural activity in some brain sites but is without effect in others, its actions are analyzed in terms of integrated connectivities in the functional circuitry of neuronal networks, which are of particular interest because of the cognitive interactions discussed in the manuscripts contributing to this review. Recent molecular data are reviewed as a support for the other contributions dealing with cognitive disturbances related to alcohol acute and addicted consumption.

Research paper thumbnail of Mécanismes neurophysiologiques mis en jeu dans des temps de réaction simple

Research paper thumbnail of Stages of Somatosensory Processing Revealed by Mapping Event-Related Potentials

Adapted behaviour requires the selective processing of the stream of sensory stimuli impinging on... more Adapted behaviour requires the selective processing of the stream of sensory stimuli impinging on the sense organs so that distinct sensory inputs become integrated into current cognition. The perceptual evaluation of inputs involves both parallel and serial brain mechanisms whose complexity must be appreciated when designing experimental paradigms.

Research paper thumbnail of Alcohol and Its Impact on Motor Control

Journal of Psychophysiology, 2010

Acute and chronic alcohol intoxications have particularly deleterious consequences on physiologic... more Acute and chronic alcohol intoxications have particularly deleterious consequences on physiological processes involving motor control and balance. This paper describes alcohol impairments to the central motor system networks in social and heavy drinkers and in individuals dependent on alcohol with or without neurological diseases.

Research paper thumbnail of The search for 'neutral' conditions for recording control event-related potentials in order to assess cognitive components to both irrelevant and relevant stimuli: evidence for short-latency cognitive somatosensory effects

Research paper thumbnail of Focal enhancement of chaotic strange attractor dimension in the left semantic (Wernicke) human cortex during reading without concomitant change in vigilance level

Neuroscience Letters, Mar 1, 1999

Research paper thumbnail of Rapport de la 2e Journée scientifique de la plateforme belge des méthodes alternatives à l'expérimentation animale. Fondation Prince Laurent

Bulletins de l'Académie Royale de Belgique, 2004

Tomberg Claude. Rapport de la 2e Journée scientifique de la plateforme belge des méthodes alterna... more Tomberg Claude. Rapport de la 2e Journée scientifique de la plateforme belge des méthodes alternatives à l'expérimentation animale. Fondation Prince Laurent.. In: Bulletin de la Classe des sciences, tome 15, n°1-6, 2004. pp. 77-80

Research paper thumbnail of PS-24-10 Is the ability to reach a high level in the motor program selectivity related to the mode of the daily manipulatory activities?

Electroencephalography and clinical neurophysiology, Sep 1, 1995

Research paper thumbnail of Categories of Alcohol Consumers

Journal of Psychophysiology, 2010

Common patterns of alcohol consumption are described with their main criteria, blood alcohol leve... more Common patterns of alcohol consumption are described with their main criteria, blood alcohol levels, and diagnostic criteria. Binge drinking, an acute alcohol intoxication pattern of particularly concern, is also described, as it appears to be the most common pattern among teenagers when the brain is not yet mature. A number of classification schemes have been proposed specially for social drinking and alcohol dependence, and discussions still surround about them. The article summarize a consensus in classification.

Research paper thumbnail of Failure to recognise objects by active touch (astereognosia) results from lesion of parietalcortex representation of finger kinaesthesis

The Lancet, Jul 1, 1999

The inability to identify objects by manipulation with eyes closed (astereognosia) results from a... more The inability to identify objects by manipulation with eyes closed (astereognosia) results from a focal cortical lesion of the second order parietal area 2, which integrates inputs from finger joints with tactile information.

Research paper thumbnail of Non-averaged human brain potentials in somatic attention: the short-latency cognition-related P40 component

The Journal of Physiology, Oct 15, 1996

Research paper thumbnail of Inadequacy of the average reference for the topographic mapping of focal enhancements of brain potentials

Clinical Neurophysiology, Jul 1, 1990

Research paper thumbnail of Nasopharyngeal recordings of somatosensory evoked potentials document the medullary origin of the N18 far-field

Clinical Neurophysiology, Nov 1, 1991

Because the nasopharyngeal électrode provides non-invasive access to the ventral brain-stem at th... more Because the nasopharyngeal électrode provides non-invasive access to the ventral brain-stem at the medullo-pontine level we used it for recording somatosensory evoked potentials (SEPs) to médian nerve stimulation (non-cephalic référence). After the P9 and Pli far-fields, the nasopharyngeal SEPs disclosed a negative-going component which was interpreted as the near-field équivalent of the P14 scalp far-field generated in the caudal part of the medial lemniscus. Nasopharyngeal SEPs also revealed a large N18 with voltage and features strikingly similar to those of the scalp-recorded N18 far-field. Thèse results suggest that N18 is generated in the medulla and not more rostrally in the brain-stem. The use of a nasopharyngeal électrode as référence for topographie brain mapping is discussed. The paper documents the feasibility and relevance of nasopharyngeal recordings for non-invasive analysis of short-latency SEPs.

Research paper thumbnail of The point correlation dimension: Performance with nonstationary surrogate data and noise

Integrative Physiological and Behavioral Science, Jul 1, 1994

Research paper thumbnail of P300 and conscious perception

Clinical Neurophysiology, 2005

info:eu-repo/semantics/publishe

Research paper thumbnail of Bit-mapping of cognitive somatosensory potentials

Electroencephalography and Clinical Neurophysiology, 1990