Achim M Loske | Universidad Nacional Autónoma de México (original) (raw)
Papers by Achim M Loske
and extracorporeal shock wave lithotripsy (SWL) now allow almost any calculus to be removed witho... more and extracorporeal shock wave lithotripsy (SWL) now allow almost any calculus to be removed without open surgery. SWL refers to the use of high intensity pressure pulses, generated outside the body, to break up kidney stones (Chaussy, Brendel, & Schmiedt, 1980; Loske, 2007). It has become the standard treatment for the majority of patients and an alternative in the management of gallbladder stones, pancreatic concrements, and salivary gland stones. Even though initial studies concluded that shock waves had no damaging effect on renal tissue, later several authors reported that shock waves may cause tissue trauma (Evan, Willis, Connors, McAteer, & Lingeman, 1991; Evan, Willis, & Lingeman, 2003 Willis et al., 1999). Fortunately, techniques and devices are still evolving and improvements to increase stone fragmentation efficiency and reduce tissue trauma are being constantly sought.
Mundo nano, May 23, 2023
Chitin is a linear polysaccharide produced by animal and fungal species. One of its sources is th... more Chitin is a linear polysaccharide produced by animal and fungal species. One of its sources is the fungus Aspergillus niger, which is culturable in industrial bioreactors. Chitin is a neutral biopolymer that modifies the electrical properties of composite materials. These are useful features in some electronic devices. This study aimed to carry out physicochemical characterizations of chitin films obtained from the above-mentioned fungus, using a chemical method enhanced with exposure to heat and shock waves, and to determine their electrical resistivity at high voltages (between 10 and 20 kV). Shock waves were used in this study because they are known to induce pores into cells and could promote alkali entry into the hypha, allowing better removal of residual cellular components. Chitin was neutralized, dried, and films were produced. Residual protein values were quantified by bicinchoninic acid assay (BCA). The films obtained had low amounts of protein. The characterization of the specific morphotype extracted was done by FTIR and XRD. An especially designed circuit revealed significant variations of the resistivity as the voltage was varied. This behavior is typical of a non-linear varistor and, to the best of our knowledge, has not been reported for chitin.
Advancements in Genetic Engineering, Oct 30, 2013
Luz M. Lopez-Marin received her M.Sc. and Ph.D. in Biochemistry from the Paul Sabatier University... more Luz M. Lopez-Marin received her M.Sc. and Ph.D. in Biochemistry from the Paul Sabatier University, Toulouse, France. She has been studying the immune response to infectious diseases at the National University of Mexico (UNAM) since 1994 and joined the Center of Applied Physics and Advanced Technology, within the same university, in 2010. She has published more than 25 papers in reputed journals. Lipoplexes and shock waves: A promising strategy for gene therapy
Advancements in Genetic Engineering, Oct 30, 2013
Biomedical applications of shock waves are continuously growing. The use of shock waves to break ... more Biomedical applications of shock waves are continuously growing. The use of shock waves to break up urinary calculi without surgery, which is known as extracorporeal shock wave lithotripsy (SWL), has led to considerable research in physics, medicine, microbiology, and molecular biology. After the first SWL the number of successful treatments increased exponentially. SWL use was expanded to other types of stones, including gallbladder stones, pancreatic calculi, and salivary gland stones. Today, shock waves are also common in orthopedics, traumatology, cardiology, rehabilitation, aesthetic therapy, and veterinary medicine. Many of these treatments, which are referred to as extracorporeal shock wave therapy (ESWT), are attracting increasing attention. The purpose of this article is to give an overview of the biomedical applications of shock waves, including some current research topics, such as, human cell transfection, and genetic transformation of bacteria and fungi.
IGI Global eBooks, Jan 18, 2011
Before 1980, the majority of patients with urolithiasis and nephrolithiasis needed surgery (Kerbl... more Before 1980, the majority of patients with urolithiasis and nephrolithiasis needed surgery (Kerbl, Rehman, Landman, Lee, Sundaram, & Clayman, 2002; Soucie et al., 1994). Fortunately, percutaneous nephrolithotomy, ureteroscopic intrarenal surgery, laparoscopic surgery, and extracorporeal shock wave lithotripsy (SWL) now allow almost any calculus to be removed without open surgery. SWL refers to the use of high intensity pressure pulses, generated outside the body, to break up kidney stones (Chaussy, Brendel, & Schmiedt, 1980; Loske, 2007). It has become the standard treatment for the majority of patients and an alternative in the management of gallbladder stones, pancreatic concrements, and salivary gland stones. Even though initial studies concluded that shock waves had no damaging effect on renal tissue, later several authors reported that shock waves may cause tissue trauma (Evan, Willis, Connors, McAteer, & Lingeman, 1991; Evan, Willis, & Lingeman, 2003 Willis et al., 1999). Fortunately, techniques and devices are still evolving and improvements to increase stone fragmentation efficiency and reduce tissue trauma are being constantly sought.
Shock wave and high pressure phenomena, Dec 3, 2016
The use of shock waves and radial pressure waves generated outside the patient’s body and deliver... more The use of shock waves and radial pressure waves generated outside the patient’s body and delivered to the affected region to trigger the body’s mechanisms to initiate natural healing, called extracorporeal shock wave therapy (ESWT) is gaining worldwide recognition and the list of indications is increasing. ESWT is often considered when easier treatment modalities have failed. Many companies offer shock wave sources that use ballistic, electrohydraulic, electromagnetic, or piezoelectric transducers to generate either shock waves or radial pressure waves. Nevertheless, more research is still needed because the cellular and molecular working mechanisms for most ESWT modalities are not fully understood. In many applications evidence is still inconclusive, mainly due to short follow-up times, small sample sizes, different parameters and equipment used, subjective scores, and lack of treatment blinding. This chapter describes some representative ESWT devices and briefly covers results of clinical applications, such as pain relief therapy, and ESWT for patients suffering from plantar fasciitis, calcaneal spur, Achilles tendinopathy, tendinopathy of the shoulder, tennis elbow, patellar tendinopathy, spasticity, chronic pelvic pain syndrome, Peyronie’s disease, and erectile dysfunction. Comments on articles reporting bone and wound healing, treatments in dermatology, acupuncture, as well as ESWT to treat heart diseases are also included. A brief section of ESWT in veterinary medicine describes that devices designed to treat indications such as stress fractures, osteoarthritis, and injuries in tendons and ligaments of horses have been on the market for many years.
Veterinaria Mexico, 1993
El presente articulo describe los resultados de las primeras pruebas in vivo en roedores y perros... more El presente articulo describe los resultados de las primeras pruebas in vivo en roedores y perros para determinar el daño causado a diferentes órganos y tejidos expuestos al generador de ondas de choque MEXILIT 1. Recibido para su piiblicación el 26 dejiinio de 1992
Gaceta UNAM (2010-2015), Jan 10, 2013
UN GRUPO DE CIENTIFICOS DEL LABORATORIO DE ONDAS DE CHOQUE DEL CENTRO DE FISICA APLICADA Y TECNOL... more UN GRUPO DE CIENTIFICOS DEL LABORATORIO DE ONDAS DE CHOQUE DEL CENTRO DE FISICA APLICADA Y TECNOLOGIA AVANZADA (CFATA) HA LOGRADO LA TRANSFORMACION GENETICA DE BACTERIAS CON UNA EFICIENCIA 50 VECES MAYOR A LOS METODOS CONVENCIONALES.
Gaceta UNAM (2000-2009), Feb 12, 2001
Applied Microbiology and Biotechnology, Oct 19, 2014
Bioengineering, Mar 30, 2023
This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY
Biotechnology and Applied Biochemistry, Jan 9, 2023
arXiv (Cornell University), Mar 29, 2018
The action of focused underwater weak shock waves on a lead sample was revealed to be not restric... more The action of focused underwater weak shock waves on a lead sample was revealed to be not restricted by a mechanical influence only. A strong unexpected x-ray emission was registered from the lead foil exposed to those shock waves (sound into x-rays) which were extremely adiabatic compared to processes of x-ray generation. The lead foil, exposed to shock waves, lost a part of its area having the shape of a polygonal hole of the size of ∼ 2mm. The missing polygon of lead foil looks as a delicately removed part with no damage at the hole surroundings as it should be after a mechanical breaking. This points to a non-mechanical mechanism of hole formation. That missing polygonal lead matter seems to be "disappeared" because the total lead volume was reduced by that amount after exposure to acoustic waves (matter collapse). Both paradoxical phenomena cannot be explained by a combination of known effects and a fundamentally new mechanism is required to underlie them. The concept of electron anomalous states, which encouraged the experiments and specified main features of them, is likely that mechanism.
UN EQUIPO MULTIDISCIPLINARIO DE CIENTIFICOS DE LA UNAM DESARROLLA UN METODO NOVEDOSO EN EL MBITO... more UN EQUIPO MULTIDISCIPLINARIO DE CIENTIFICOS DE LA UNAM DESARROLLA UN METODO NOVEDOSO EN EL MBITO INTERNACIONAL, BASADO EN ONDAS DE CHOQUE, QUE PODRIA SER UTIL PARA LA CONSERVACION DE ALIMENTOS Y PARA TRATAR INFECCIONES LOCALIZADAS Y PERSISTENTES, FRECUENTES EN ORGANOS COMO LA VESICULA BILIAR Y LA PROSTATA. ESAS ONDAS -CUYO ESTUDIO ES LIDERADO POR ACHIM LOSKE, DEL CENTRO DE FISICA APLICADA Y TECNOLOGIA AVANZADA (CFATA), CON SEDE EN JURIQUILLA, QUERETARO- FUNCIONARIAN COMO UNA TECNICA ALTERNATIVA DE TRATAMIENTO NO TERMICO DE COMESTIBLES. AUNQUE VA M S ALL , PORQUE TENDRIA UN ALTO POTENCIAL MEDICO PARA DESTRUIR BACTERIAS DENTRO DEL ORGANISMO. HASTA AHORA SE HAN EMPLEADO METODOS CONVENCIONALES PARA ELIMINAR MICROORGANISMOS DE DIFERENTES PRODUCTOS COMO LA PASTEURIZACION, CONSISTENTE EN AUMENTAR LA TEMPERATURA PARA INACTIVAR A LOS GERMENES. NO OBSTANTE, ADVIRTIO EL CIENTIFICO, CON ESE PROCESO SE MODIFICAN LAS PROPIEDADES ORGANOLEPTICAS -SABOR, COLOR U OLOR- E, INCLUSO, NUTRICIONALES. EN ...
Perhaps one of the brightest, and certainly the funniest, theoretical physicists of the XXth cent... more Perhaps one of the brightest, and certainly the funniest, theoretical physicists of the XXth century was the author of the phrase that gives the title to this present Comment: Richard Phillips Feynman (1918–1988) who, according to tradition, left written onto his blackboard, at the California Institute of Technology, precisely that “what I cannot create, I do not understand”, shortly before his death [1–3]. For several generations of physics students around the globe, Nobel Prize Laureate Feynman has represented an icon of how creativity, ingenuity, and little respect for the establishment, can lead to great discoveries and, along the way, have fun with the type of science which dares to overcome disciplinary boundaries. Feynman was always not only interested in Biology, but also puzzled by how biological problems seemed to challenge the, otherwise, successful tools developed by the same theoretical physics that helped to change our vision of the world and which has rocketed the dev...
Ciencia Y Desarrollo, 1991
and extracorporeal shock wave lithotripsy (SWL) now allow almost any calculus to be removed witho... more and extracorporeal shock wave lithotripsy (SWL) now allow almost any calculus to be removed without open surgery. SWL refers to the use of high intensity pressure pulses, generated outside the body, to break up kidney stones (Chaussy, Brendel, & Schmiedt, 1980; Loske, 2007). It has become the standard treatment for the majority of patients and an alternative in the management of gallbladder stones, pancreatic concrements, and salivary gland stones. Even though initial studies concluded that shock waves had no damaging effect on renal tissue, later several authors reported that shock waves may cause tissue trauma (Evan, Willis, Connors, McAteer, & Lingeman, 1991; Evan, Willis, & Lingeman, 2003 Willis et al., 1999). Fortunately, techniques and devices are still evolving and improvements to increase stone fragmentation efficiency and reduce tissue trauma are being constantly sought.
Mundo nano, May 23, 2023
Chitin is a linear polysaccharide produced by animal and fungal species. One of its sources is th... more Chitin is a linear polysaccharide produced by animal and fungal species. One of its sources is the fungus Aspergillus niger, which is culturable in industrial bioreactors. Chitin is a neutral biopolymer that modifies the electrical properties of composite materials. These are useful features in some electronic devices. This study aimed to carry out physicochemical characterizations of chitin films obtained from the above-mentioned fungus, using a chemical method enhanced with exposure to heat and shock waves, and to determine their electrical resistivity at high voltages (between 10 and 20 kV). Shock waves were used in this study because they are known to induce pores into cells and could promote alkali entry into the hypha, allowing better removal of residual cellular components. Chitin was neutralized, dried, and films were produced. Residual protein values were quantified by bicinchoninic acid assay (BCA). The films obtained had low amounts of protein. The characterization of the specific morphotype extracted was done by FTIR and XRD. An especially designed circuit revealed significant variations of the resistivity as the voltage was varied. This behavior is typical of a non-linear varistor and, to the best of our knowledge, has not been reported for chitin.
Advancements in Genetic Engineering, Oct 30, 2013
Luz M. Lopez-Marin received her M.Sc. and Ph.D. in Biochemistry from the Paul Sabatier University... more Luz M. Lopez-Marin received her M.Sc. and Ph.D. in Biochemistry from the Paul Sabatier University, Toulouse, France. She has been studying the immune response to infectious diseases at the National University of Mexico (UNAM) since 1994 and joined the Center of Applied Physics and Advanced Technology, within the same university, in 2010. She has published more than 25 papers in reputed journals. Lipoplexes and shock waves: A promising strategy for gene therapy
Advancements in Genetic Engineering, Oct 30, 2013
Biomedical applications of shock waves are continuously growing. The use of shock waves to break ... more Biomedical applications of shock waves are continuously growing. The use of shock waves to break up urinary calculi without surgery, which is known as extracorporeal shock wave lithotripsy (SWL), has led to considerable research in physics, medicine, microbiology, and molecular biology. After the first SWL the number of successful treatments increased exponentially. SWL use was expanded to other types of stones, including gallbladder stones, pancreatic calculi, and salivary gland stones. Today, shock waves are also common in orthopedics, traumatology, cardiology, rehabilitation, aesthetic therapy, and veterinary medicine. Many of these treatments, which are referred to as extracorporeal shock wave therapy (ESWT), are attracting increasing attention. The purpose of this article is to give an overview of the biomedical applications of shock waves, including some current research topics, such as, human cell transfection, and genetic transformation of bacteria and fungi.
IGI Global eBooks, Jan 18, 2011
Before 1980, the majority of patients with urolithiasis and nephrolithiasis needed surgery (Kerbl... more Before 1980, the majority of patients with urolithiasis and nephrolithiasis needed surgery (Kerbl, Rehman, Landman, Lee, Sundaram, & Clayman, 2002; Soucie et al., 1994). Fortunately, percutaneous nephrolithotomy, ureteroscopic intrarenal surgery, laparoscopic surgery, and extracorporeal shock wave lithotripsy (SWL) now allow almost any calculus to be removed without open surgery. SWL refers to the use of high intensity pressure pulses, generated outside the body, to break up kidney stones (Chaussy, Brendel, & Schmiedt, 1980; Loske, 2007). It has become the standard treatment for the majority of patients and an alternative in the management of gallbladder stones, pancreatic concrements, and salivary gland stones. Even though initial studies concluded that shock waves had no damaging effect on renal tissue, later several authors reported that shock waves may cause tissue trauma (Evan, Willis, Connors, McAteer, & Lingeman, 1991; Evan, Willis, & Lingeman, 2003 Willis et al., 1999). Fortunately, techniques and devices are still evolving and improvements to increase stone fragmentation efficiency and reduce tissue trauma are being constantly sought.
Shock wave and high pressure phenomena, Dec 3, 2016
The use of shock waves and radial pressure waves generated outside the patient’s body and deliver... more The use of shock waves and radial pressure waves generated outside the patient’s body and delivered to the affected region to trigger the body’s mechanisms to initiate natural healing, called extracorporeal shock wave therapy (ESWT) is gaining worldwide recognition and the list of indications is increasing. ESWT is often considered when easier treatment modalities have failed. Many companies offer shock wave sources that use ballistic, electrohydraulic, electromagnetic, or piezoelectric transducers to generate either shock waves or radial pressure waves. Nevertheless, more research is still needed because the cellular and molecular working mechanisms for most ESWT modalities are not fully understood. In many applications evidence is still inconclusive, mainly due to short follow-up times, small sample sizes, different parameters and equipment used, subjective scores, and lack of treatment blinding. This chapter describes some representative ESWT devices and briefly covers results of clinical applications, such as pain relief therapy, and ESWT for patients suffering from plantar fasciitis, calcaneal spur, Achilles tendinopathy, tendinopathy of the shoulder, tennis elbow, patellar tendinopathy, spasticity, chronic pelvic pain syndrome, Peyronie’s disease, and erectile dysfunction. Comments on articles reporting bone and wound healing, treatments in dermatology, acupuncture, as well as ESWT to treat heart diseases are also included. A brief section of ESWT in veterinary medicine describes that devices designed to treat indications such as stress fractures, osteoarthritis, and injuries in tendons and ligaments of horses have been on the market for many years.
Veterinaria Mexico, 1993
El presente articulo describe los resultados de las primeras pruebas in vivo en roedores y perros... more El presente articulo describe los resultados de las primeras pruebas in vivo en roedores y perros para determinar el daño causado a diferentes órganos y tejidos expuestos al generador de ondas de choque MEXILIT 1. Recibido para su piiblicación el 26 dejiinio de 1992
Gaceta UNAM (2010-2015), Jan 10, 2013
UN GRUPO DE CIENTIFICOS DEL LABORATORIO DE ONDAS DE CHOQUE DEL CENTRO DE FISICA APLICADA Y TECNOL... more UN GRUPO DE CIENTIFICOS DEL LABORATORIO DE ONDAS DE CHOQUE DEL CENTRO DE FISICA APLICADA Y TECNOLOGIA AVANZADA (CFATA) HA LOGRADO LA TRANSFORMACION GENETICA DE BACTERIAS CON UNA EFICIENCIA 50 VECES MAYOR A LOS METODOS CONVENCIONALES.
Gaceta UNAM (2000-2009), Feb 12, 2001
Applied Microbiology and Biotechnology, Oct 19, 2014
Bioengineering, Mar 30, 2023
This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY
Biotechnology and Applied Biochemistry, Jan 9, 2023
arXiv (Cornell University), Mar 29, 2018
The action of focused underwater weak shock waves on a lead sample was revealed to be not restric... more The action of focused underwater weak shock waves on a lead sample was revealed to be not restricted by a mechanical influence only. A strong unexpected x-ray emission was registered from the lead foil exposed to those shock waves (sound into x-rays) which were extremely adiabatic compared to processes of x-ray generation. The lead foil, exposed to shock waves, lost a part of its area having the shape of a polygonal hole of the size of ∼ 2mm. The missing polygon of lead foil looks as a delicately removed part with no damage at the hole surroundings as it should be after a mechanical breaking. This points to a non-mechanical mechanism of hole formation. That missing polygonal lead matter seems to be "disappeared" because the total lead volume was reduced by that amount after exposure to acoustic waves (matter collapse). Both paradoxical phenomena cannot be explained by a combination of known effects and a fundamentally new mechanism is required to underlie them. The concept of electron anomalous states, which encouraged the experiments and specified main features of them, is likely that mechanism.
UN EQUIPO MULTIDISCIPLINARIO DE CIENTIFICOS DE LA UNAM DESARROLLA UN METODO NOVEDOSO EN EL MBITO... more UN EQUIPO MULTIDISCIPLINARIO DE CIENTIFICOS DE LA UNAM DESARROLLA UN METODO NOVEDOSO EN EL MBITO INTERNACIONAL, BASADO EN ONDAS DE CHOQUE, QUE PODRIA SER UTIL PARA LA CONSERVACION DE ALIMENTOS Y PARA TRATAR INFECCIONES LOCALIZADAS Y PERSISTENTES, FRECUENTES EN ORGANOS COMO LA VESICULA BILIAR Y LA PROSTATA. ESAS ONDAS -CUYO ESTUDIO ES LIDERADO POR ACHIM LOSKE, DEL CENTRO DE FISICA APLICADA Y TECNOLOGIA AVANZADA (CFATA), CON SEDE EN JURIQUILLA, QUERETARO- FUNCIONARIAN COMO UNA TECNICA ALTERNATIVA DE TRATAMIENTO NO TERMICO DE COMESTIBLES. AUNQUE VA M S ALL , PORQUE TENDRIA UN ALTO POTENCIAL MEDICO PARA DESTRUIR BACTERIAS DENTRO DEL ORGANISMO. HASTA AHORA SE HAN EMPLEADO METODOS CONVENCIONALES PARA ELIMINAR MICROORGANISMOS DE DIFERENTES PRODUCTOS COMO LA PASTEURIZACION, CONSISTENTE EN AUMENTAR LA TEMPERATURA PARA INACTIVAR A LOS GERMENES. NO OBSTANTE, ADVIRTIO EL CIENTIFICO, CON ESE PROCESO SE MODIFICAN LAS PROPIEDADES ORGANOLEPTICAS -SABOR, COLOR U OLOR- E, INCLUSO, NUTRICIONALES. EN ...
Perhaps one of the brightest, and certainly the funniest, theoretical physicists of the XXth cent... more Perhaps one of the brightest, and certainly the funniest, theoretical physicists of the XXth century was the author of the phrase that gives the title to this present Comment: Richard Phillips Feynman (1918–1988) who, according to tradition, left written onto his blackboard, at the California Institute of Technology, precisely that “what I cannot create, I do not understand”, shortly before his death [1–3]. For several generations of physics students around the globe, Nobel Prize Laureate Feynman has represented an icon of how creativity, ingenuity, and little respect for the establishment, can lead to great discoveries and, along the way, have fun with the type of science which dares to overcome disciplinary boundaries. Feynman was always not only interested in Biology, but also puzzled by how biological problems seemed to challenge the, otherwise, successful tools developed by the same theoretical physics that helped to change our vision of the world and which has rocketed the dev...
Ciencia Y Desarrollo, 1991