Juan Gutierrez V | UNAM Universidad Nacional Autónoma de México (original) (raw)

Papers by Juan Gutierrez V

This document shows the relationship among organizational culture, job satisfaction and engagemen... more This document shows the relationship among organizational culture, job satisfaction and engagement in the garment industry in Piedecuesta. For the development of this investigation, the organizational culture was determined taking into account the following dimensions: dominant characteristics, leaders of the organization, management style, union of the organization, strategic emphasis and criteria of success, by means of the OCAI questionnaire. On the other hand, the level of job satisfaction was defined with the variables working conditions, participation in decisions, relationship with superiors, work, and recognition, by applying the job satisfaction questionnaire S20/23. Likewise, engagement was determined with the dimensions vigor, dedication, and absorption, applying the UWES-17 questionnaire. Finally, the relationship was examined using the Spearman correlation. The findings indicate that good relationships should be fostered and the gaps that may exist between worker-employ...

Revista Facultad de Ciencias Contables Económicas y Administrativas -FACCEA, 2020

La cultura de la innovación es fundamental para cualquier sector económico, ya que facilita la ge... more La cultura de la innovación es fundamental para cualquier sector económico, ya que facilita la generación de nuevos productos, servicios o procesos los cuales pueden contribuir al crecimiento y competitividad. Una de las industrias donde esta tiene alta importancia es el sector hotelero, el cual ha tenido fuerte impacto sobre la economía de varios países a lo largo de la historia, Colombia, no es la excepción. No obstante, algunas regiones, como Santander, carecen de perfilamientos detallados de la innovación de este sector. En este sentido, el presente artículo busca describir la cultura de la innovación de los establecimientos hoteleros de Santander; para esto, se aplicó una metodología cualitativa exploratoria con la que se encontró que los pilares más fuertes de esta cultura son la “estrategia” y las “personas”, pero es necesario reforzar la “gestión” mediante actividades de ideación, capacitaciones sobre nuevas tendencias y mayores recursos económicos destinados a iniciativas i...

Criterio Libre, 2021

El presente artículo presenta una revisión de literatura referente a la gestión del conocimiento,... more El presente artículo presenta una revisión de literatura referente a la gestión del conocimiento, teniendo en cuenta la importancia de esta en las organizaciones particularmente en el sector turístico hotelero, producto de la complejidad de los entornos de esta industria. Para tal fin, se realizó una fundamentación teórica, seguidamente se referencian los tipos de conocimiento, posteriormente la presentación de los modelos y los procesos, y finalmente lo relacionado con la actividad hotelera. De igual modo, se plantean una serie de conclusiones, propendiendo el desarrollo de investigaciones, así mismo, se precisa el uso de planos temporales, con el fin de impulsar la rigurosidad metodológica. Los hallazgos de este trabajo indican que la gestión del conocimiento tiene gran importancia en el contexto actual, pues contribuye en la generación de una ventaja competitiva sostenible.

Coronavirus disease 2019 (COVID-19) is a novel human respiratory disease caused by the SARS-CoV-2... more Coronavirus disease 2019 (COVID-19) is a novel human respiratory disease caused by the SARS-CoV-2 virus. Asymptomatic carriers of the virus display no clinical symptoms but are known to be contagious. Recent evidence reveals that this sub-population, as well as persons with mild disease, are a major contributor in the propagation of COVID-19. The asymptomatic sub-population frequently escapes detection by public health surveillance systems. Because of this, the currently accepted estimates of the basic reproduction number (R 0) of the disease are inaccurate. It is unlikely that a pathogen can blanket the planet in three months with an R 0 in the

Bulletin of Mathematical Biology, 2020

Asymptomatic individuals in the context of malarial disease are subjects who carry a parasite loa... more Asymptomatic individuals in the context of malarial disease are subjects who carry a parasite load, but do not show clinical symptoms. A correct understanding of the influence of asymptomatic individuals on transmission dynamics will provide a comprehensive description of the complex interplay between the definitive host (female Anopheles mosquito), intermediate host (human), and agent (Plasmodium parasite). The goal of this article is to conduct a rigorous mathematical analysis of a new compartmentalized malaria model accounting for asymptomatic human hosts for the purpose of calculating the basic reproductive number ($$\mathcal {R}_0$$R0) and determining the bifurcations that might occur at the onset of disease-free equilibrium. A point of departure of this model from others appearing in the literature is that the asymptomatic compartment is decomposed into two mutually disjoint sub-compartments by making use of the naturally acquired immunity of the population under consideration...

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Frontiers in genetics, 2018

Metallothioneins (MT) are multi-stress proteins mainly involved in metal detoxification. MT gene ... more Metallothioneins (MT) are multi-stress proteins mainly involved in metal detoxification. MT gene expression is normally induced by a broad variety of stimulus and its gene expression regulation mainly occurs at a transcriptional level. Conserved motifs in the MT promoters have been described. These motifs show a consensus sequence very similar to AP-1 sites, and bZIP type transcription factors might participate in the MT gene expression regulation. In this research work, we characterize four AP-1 transcription factors in each of four different analyzed species, detecting a high conservation among them. Each AP-1 molecule has its counterpart in the other three species. A comparative qRT-PCR analysis of these AP-1 genes have been carried out in different strains (including metal-adapted, knockout and/or knockdown strains among others), and under different metal-stress conditions (1 or 24 h Cd, Cu, or Pb treatments). The possible interaction of these transcription factors with the cons...

Musculoskeletal care, Mar 13, 2017

The aim of the present study was to evaluate the effectiveness of an educational tool for general... more The aim of the present study was to evaluate the effectiveness of an educational tool for general physicians, based on rheumatological clinical simulation, for the diagnosis of rheumatoid arthritis and osteoarthritis. A randomized clinical study was carried out, in which the physician research subjects were assigned to one of two groups: the experimental group (educational intervention for rheumatoid arthritis with clinical simulation) or the control group (educational intervention for the basic aspects of the diagnosis and treatment of osteoporosis). Four weeks after the educational intervention, the members of both groups completed an examination that included four clinical cases with real patients, two clinical cases with two clinical simulation models and six virtual clinical cases. In this examination, the participants noted clinical findings, established a diagnosis and defined the complementary tests they would request, if necessary, to corroborate their diagnosis. A total of...

Renewable Energy and Power Quality Journal, 2009

Voltage fluctuations related to light flicker can propagate along a distribution network with the... more Voltage fluctuations related to light flicker can propagate along a distribution network with their attenuation being affected by the topology of the network, the line impedances, and the characteristics of the loads and the transformers. The propagation leads to different simultaneous flicker measurements at different voltage levels. This work documents a case study in which three points in a distribution network were monitored, with the flicker level being measured simultaneously at 132KV, 30KV, and 13KV. Two types of flicker transfer coefficient are discussed, taking into account the impact of different types of loads, the spectral characteristics involved in the flicker measurements, and possible strategies for flagging dip events at the three voltage levels.

Gynecologic Oncology Reports, 2017

Investigación en Educación Médica, 2017

Introduction: Anatomy is considered a cornerstone in human and veterinary medical education, as t... more Introduction: Anatomy is considered a cornerstone in human and veterinary medical education, as this basic science discipline provides a vital foundation on which to build the knowledge of the clinical practice of medicine. Objective: The aims of this study were: 1) to collect information on first year veterinary student preference, and use of supportive educational tools, and 2) to assess long-term knowledge retention in senior veterinary students who successfully completed the bovine anatomy course. Method: A survey was administered to first-year veterinary students in order to identify their learning tools of choice, and a diagnostic examination was designed to reflect highly relevant basic anatomy knowledge was administered to senior veterinary students. Results: Besides the regular cadaver-dissection laboratories, textbooks were the tool used most frequently by first-year students to learn bovine anatomy. Computer technology was used by only 12.2% of the students. When evaluating knowledge retention of bovine anatomy by fourth year (senior) students, only 33.2% of the questions were answered correctly in the fourth year examination. Conclusions: These results were interpreted as a low long-term retention of knowledge in Chilean veterinary medical students.

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, Jan 29, 2015

Ultrasound-guided interscalene brachial plexus blocks are commonly used to provide anesthesia for... more Ultrasound-guided interscalene brachial plexus blocks are commonly used to provide anesthesia for the shoulder and proximal upper extremity. Some reviews identify a sheath that envelops the brachial plexus as a potential tissue plane target, and current editorials in the literature highlight the need to establish precise and reproducible injection targets under ultrasound guidance. We hypothesize that an injection of a local anesthetic inside the brachial plexus sheath during ultrasound-guided interscalene nerve blocks will result in enhanced procedure success and provide a consistent tissue plane target for this approach with a reproducible and characteristic local anesthetic spread pattern. Sixty patients scheduled for shoulder surgery with a preoperative interscalene block for postoperative pain management were enrolled in this prospective randomized observer-blinded study. Each patient was randomly assigned to receive a single-shot interscalene block either inside or outside the...

Mathematical biosciences, Jan 8, 2015

We study a time dependent partial differential equation (PDE) which arises from classic models in... more We study a time dependent partial differential equation (PDE) which arises from classic models in ecology involving logistic growth with Allee effect by introducing a discrete weak solution. Existence, uniqueness and stability of the discrete weak solutions are discussed. We use bivariate splines to approximate the discrete weak solution of the nonlinear PDE. A computational algorithm is designed to solve this PDE. A convergence analysis of the algorithm is presented. We present some simulations of population development over some irregular domains. Finally, we discuss applications in epidemiology and other ecological problems.

Lecture Notes in Computer Science, 2004

Ad Hoc networking is a technology that is gaining relevance. It is still an area under developmen... more Ad Hoc networking is a technology that is gaining relevance. It is still an area under development where there are multiple open items such as routing, addressing, interoperability and service distribution. However, one of the major problems is the scalability. Most of the protocols designed specifically for Ad Hoc networks show scalability problems. In this paper, we propose network architecture

Mathematical biosciences, Jan 15, 2015

Since their earliest days, humans have been struggling with infectious diseases. Caused by viruse... more Since their earliest days, humans have been struggling with infectious diseases. Caused by viruses, bacteria, protozoa, or even higher organisms like worms, these diseases depend critically on numerous intricate interactions between parasites and hosts, and while we have learned much about these interactions, many details are still obscure. It is evident that the combined host-parasite dynamics constitutes a complex system that involves components and processes at multiple scales of time, space, and biological organization. At one end of this hierarchy we know of individual molecules that play crucial roles for the survival of a parasite or for the response and survival of its host. At the other end, one realizes that the spread of infectious diseases by far exceeds specific locales and, due to today's easy travel of hosts carrying a multitude of organisms, can quickly reach global proportions. The community of mathematical modelers has been addressing specific aspects of infect...

International Journal of Biological Sciences, 2015

The metal binding preference of metallothioneins (MTs) groups them in two extreme subsets, the Zn... more The metal binding preference of metallothioneins (MTs) groups them in two extreme subsets, the Zn/Cd-and the Cu-thioneins. Ciliates harbor the largest MT gene/protein family reported so far, including 5 paralogs that exhibit relatively low sequence similarity, excepting MTT2 and MTT4. In Tetrahymena thermophila, three MTs (MTT1, MTT3 and MTT5) were considered Cd-thioneins and two (MTT2 and MTT4) Cu-thioneins, according to gene expression inducibility and phylogenetic analysis. In this study, the metal-binding abilities of the five MTT proteins were characterized, to obtain information about the folding and stability of their cognate-and non-cognate metal complexes, and to characterize the T. thermophila MT system at protein level. Hence, the five MTTs were recombinantly synthesized as Zn 2+-, Cd 2+-or Cu +-complexes, which were analyzed by electrospray mass spectrometry (ESI-MS), circular dichroism (CD), and UV-vis spectrophotometry. Among the Cd-thioneins, MTT1 and MTT5 were optimal for Cd 2+ coordination, yielding unique Cd17-and Cd8-complexes, respectively. When binding Zn 2+ , they rendered a mixture of Zn-species. Only MTT5 was capable to coordinate Cu + , although yielding heteronuclear Zn-, Cu-species or highly unstable Cu-homometallic species. MTT3 exhibited poor binding abilities both for Cd 2+ and for Cu + , and although not optimally, it yielded the best result when coordinating Zn 2+. The two Cu-thioneins, MTT2 and MTT4 isoforms formed homometallic Cu-complexes (major Cu20-MTT) upon synthesis in Cu-supplemented hosts. Contrarily, they were unable to fold into stable Cd-complexes, while Zn-MTT species were only recovered for MTT4 (major Zn10-MTT4). Thus, the metal binding preferences of the five T. thermophila MTs correlate well with their previous classification as Cd-and Cu-thioneins, and globally, they can be classified from Zn/Cd-to Cu-thioneins according to the gradation: MTT1>MTT5>MTT3>MTT4>MTT2. The main mechanisms underlying the evolution and specialization of the MTT metal binding preferences may have been internal tandem duplications, presence of doublet and triplet Cys patterns in Zn/Cd-thioneins, and optimization of site specific amino acid determinants (Lys for Zn/Cd-and Asn for Cu-coordination).

Frontiers in Microbiology, 2015

This review analyzes the advantages and disadvantages of using eukaryotic microorganisms to desig... more This review analyzes the advantages and disadvantages of using eukaryotic microorganisms to design whole-cell biosensors (WCBs) for monitoring environmental heavy metal pollution in soil or aquatic habitats. Basic considerations for designing a eukaryotic WCB are also shown. A comparative analysis of the promoter genes used to design WCBs is carried out, and the sensitivity and reproducibility of the main reporter genes used is also reviewed. Three main eukaryotic taxonomic groups are considered: yeasts, microalgae, and ciliated protozoa. Models that have been widely analyzed as potential WCBs are the Saccharomyces cerevisiae model among yeasts, the Tetrahymena thermophila model for ciliates and Chlamydomonas model for microalgae. The advantages and disadvantages of each microbial group are discussed, and a ranking of sensitivity to the same type of metal pollutant from reported eukaryotic WCBs is also shown. General conclusions and possible future developments of eukaryotic WCBs are reported.

Policy Research Working Papers, 2012

The Policy Research Working Paper Series disseminates the findings of work in progress to encoura... more The Policy Research Working Paper Series disseminates the findings of work in progress to encourage the exchange of ideas about development issues. An objective of the series is to get the findings out quickly, even if the presentations are less than fully polished. The papers carry the names of the authors and should be cited accordingly. The findings, interpretations, and conclusions expressed in this paper are entirely those of the authors. They do not necessarily represent the views of the International Bank for Reconstruction and Development/World Bank and its affiliated organizations, or those of the Executive Directors of the World Bank or the governments they represent.

Electrical Transmission and Substation Structures 2012, 2012

The prevalent coal mining technique in the United States and other countries is called long wall ... more The prevalent coal mining technique in the United States and other countries is called long wall mining and eventually removes entirely coal seams over extended areas. The removal causes subsidence settlement and horizontal displacements of several feet above the mined seam. Structures located at the surface of affected areas are subjected to differential foundation displacements that can induce stresses beyond the capacity of structural members. It is desirable to preserve the integrity of affected structures not only to avoid costly repairs or replacements but also because they house electrical and industrial equipment that must remain operational. This paper first describes a recent development in the prediction of ground displacements, rotations and curvatures caused by mine subsidence. Then we present the concepts, analyses and design of structural measures for mitigating the anticipated effects of mine subsidence and to alleviate any observed distress during the event.

Nature Precedings, 2010

Cell cycle progression through mitosis and meiosis involves regulation by serine/threonine kinase... more Cell cycle progression through mitosis and meiosis involves regulation by serine/threonine kinases from the aurora family. Aurora kinase b (Aurkb) is mainly involved in the proper segregation of chromosomes during mitosis as well as meiosis. However, over expression of Aurkb leads to the unequal distribution of genetic information creating aneuploid cells, a hallmark of cancer. Thus, Aurkb can be used as an effective molecular target for computer-aided drug discovery against cancer. Existing Aurkb inhibitors are less efficient, hence an in silico work was carried out to identify novel potent inhibitors. Three published inhibitors azd1152, zm447439 and N-(4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy) quinazolin- 4-yl] amino} phenyl) benzamide were subjected to high throughput virtual screening of over 1 million entries from a ligand info meta database, to generate a 1161 compound library. The crystal structure was optimized and energy was minimized applying an OPLS force field in Maestro...