Hans Biesalski | University of Hohenheim, Stuttgart (original) (raw)
Papers by Hans Biesalski
Social Science Research Network, 2015
Asian journal of complementary and alternative medicine, Jun 1, 2021
Advances in Nutrition, Mar 1, 2012
International Journal of Tropical Insect Science, Feb 18, 2020
The sago grub (Rhynchophorus bilineatus) [Montrouzier, Coleoptera, Dryophthoridae] is a local del... more The sago grub (Rhynchophorus bilineatus) [Montrouzier, Coleoptera, Dryophthoridae] is a local delicacy in the Papua Province in Indonesia. In this study, the nutrient content of the edible insect was measured using chromatographic and spectrometric methods. The results showed that it contains 10.39 g protein and 17.17 g oil/ 100 g fresh weight. The sago grub meets the FAO/ WHO requirements of 40% essential amino acids and a 0.60 ratio between essential to non-essential amino acids. Its limiting amino acid is methionine + cysteine. The major fatty acids found in the sago grub are palmitic (42%), oleic (45%), and linoleic (3%) acids. Although vitamin E is exclusively produced by photosynthetic organisms, a gram of sago grub oil contains 51 μg vitamin E, which is composed mainly of tocopherols (92%). In contrast with palm oil, the sago grub oil contains δ-tocopherol (0.12 μg/g oil), and a significantly high amount of β-tocopherol (3.85 μg/g oil). It is a source of zinc and magnesium and contains safe levels of heavy metals. Based on these nutritional properties, the Indonesian sago grub can be considered as a good source of nutrients, and its propagation and utilization should be encouraged especially in other areas of Indonesia and maybe in neighboring countries where they are also endemic, and where malnutrition is prevalent. The consumption of edible insects should be considered as a component of dietary diversificationa sustainable way of alleviating the nutritional status of the population.
Ernährung & Medizin, 2018
ZusammenfassungWenn es um gesunde Ernährung und dabei ganz besonders um Vitamine geht, so wird im... more ZusammenfassungWenn es um gesunde Ernährung und dabei ganz besonders um Vitamine geht, so wird immer wieder darauf hingewiesen: „Wir brauchen keine (zusätzlichen) Vitamine, wir haben genug Obst und Gemüse!“ Beides ist nicht wirklich richtig! Natürlich brauchen wir Vitamine und wir haben durchaus auch genügend Obst und Gemüse. Allerdings sind Obst und Gemüse nicht alleine ausreichend, wenn es um die Versorgung mit Vitaminen geht!
Diätetik und Arteriosklerose, 1993
Under nutrition and food insecurity are major problems faced by most of the developing countries ... more Under nutrition and food insecurity are major problems faced by most of the developing countries including Tanzania. Approximately 42% of children below five years of age are stunted as a result of chronic undernutrition. Vitamin and mineral deficiencies are also very high where by about 59% and 34% of children below five years are iron and vitamin A deficient respectively and 48% of women are iodine deficient (National Bureau of Statistics [NBS] & ICF Macro, 2010). Foods with high nutrient content (vegetables and fruits) are difficult to find in the poorer rural areas during the dry seasons. Moreover rural households are affected with increasing food prices due to their low purchasing power (Adekunle, 2013). During this time, most people in rural areas are dependent on staple foods with little diversity.
Current Developments in Nutrition, 2019
Objectives Despite the availability of effective antimicrobials, tuberculosis (TB) remains as a p... more Objectives Despite the availability of effective antimicrobials, tuberculosis (TB) remains as a public health threat globally. There is a need for simple and inexpensive strategies to improve the treatment outcomes.The objective of our study was to deal with the potential use of vitamin D2 derived from sun-exposed oyster mushroom as adjunctive therapy to standard anti-TB treatment Methods Randomized controlled trial was conducted on 64 pulmonary TB patients (32 assigned to intervention and 32 assigned to control) in North Shewa, Ethiopia. Intervention group was provided with a sandwich prepared from sun-exposed oyster mushroom containing 146 µg (5840 IU) vitamin D2 continuously from Monday to Friday during the first 16 weeks of anti-TB treatment. Blood and sputum specimens were taken at the beginning and end of the study. The primary outcomes were changes in vitamin D status, clinical improvements (assessed by TB score and Karnofsky performance status scale) and immunologic response...
Zeitschrift für Phytotherapie, 2019
Clinical Interventions in Aging, 2018
Purpose: Despite some reports of high prevalence of thiamine deficiency in elderly people, the re... more Purpose: Despite some reports of high prevalence of thiamine deficiency in elderly people, the reported prevalence is controversial mainly due to the methods used in assessing thiamin concentrations. In this study, we sought to investigate the prevalence of vitamin B1 deficiency, using the high-performance liquid chromatography (HPLC) method, among older hospitalized patients. Patients and methods: This cross-sectional study retrospectively analyzed the results of routine measurements of vitamin B1 of 238 older patients who were consecutively hospitalized to a geriatric acute care ward. Whole blood vitamin B1 concentrations were measured using the HPLC method at hospital admission, and the whole blood vitamin B1 level of ,20 ng/mL was considered as deficiency. Results: Of 238 patients, with a mean age of 82.1±7.1 years, 63% of patients were women. In total, the mean whole blood vitamin B1 level was 66.1±24.8 ng/mL (range 29.5-215 ng/mL), indicating no vitamin B1 deficiency in the entire population. In addition, no significant differences in the mean whole blood vitamin B1 concentrations between sexes were observed (P=0.356). Conclusion: This study indicates that the mean whole blood vitamin B1 concentrations using the HPLC method were within the normal range in older hospitalized patients suggesting that thiamine deficiency appears to be rather uncommon among these patients.
British Journal of Cancer, 1989
International Journal of Obesity, 2004
Critical care (London, England), Jan 27, 2014
The use of vitamin C against different diseases has been controversially and emotionally discusse... more The use of vitamin C against different diseases has been controversially and emotionally discussed since Linus Pauling published his cancer studies. In vitro and animal studies showed promising results and explained the impact of vitamin C, particularly in cases with endothelial dysfunction. Indeed, studies (reviewed in this issue of Critical Care by Oudemans-van Straaten and colleagues) using high-dose vitamin C and the parenteral route of application seem to be more successful than oral vitamin C delivery.
Cancer research, Jan 15, 1988
BA-HAN-1C is a clonal rat rhabdomyosarcoma cell line composed of proliferating mononuclear cells,... more BA-HAN-1C is a clonal rat rhabdomyosarcoma cell line composed of proliferating mononuclear cells, which partly fuse to terminally differentiated postmitotic myotube-like giant cells. The exposure to retinoic acid in vitro resulted in time- and dose-dependent changes of both cell differentiation and cell growth. The mononuclear cells revealed bundles of newly formed thick and thin myofilaments, never observed in untreated cultures, and exhibited signs of contact inhibition. In addition, there was a statistically significant increase (P less than 0.001) in the number of terminally differentiated postmitotic myotube-like giant cells and in the creatine kinase activity (P less than 0.05) which was used as a biochemical differentiation marker. At the same time cell growth was significantly inhibited (P less than 0.001) in vitro and a decrease in plating efficiency, as well as in saturation density, was observed. These data demonstrate that retinoic acid can suppress cell growth and simul...
Social Science Research Network, 2015
Asian journal of complementary and alternative medicine, Jun 1, 2021
Advances in Nutrition, Mar 1, 2012
International Journal of Tropical Insect Science, Feb 18, 2020
The sago grub (Rhynchophorus bilineatus) [Montrouzier, Coleoptera, Dryophthoridae] is a local del... more The sago grub (Rhynchophorus bilineatus) [Montrouzier, Coleoptera, Dryophthoridae] is a local delicacy in the Papua Province in Indonesia. In this study, the nutrient content of the edible insect was measured using chromatographic and spectrometric methods. The results showed that it contains 10.39 g protein and 17.17 g oil/ 100 g fresh weight. The sago grub meets the FAO/ WHO requirements of 40% essential amino acids and a 0.60 ratio between essential to non-essential amino acids. Its limiting amino acid is methionine + cysteine. The major fatty acids found in the sago grub are palmitic (42%), oleic (45%), and linoleic (3%) acids. Although vitamin E is exclusively produced by photosynthetic organisms, a gram of sago grub oil contains 51 μg vitamin E, which is composed mainly of tocopherols (92%). In contrast with palm oil, the sago grub oil contains δ-tocopherol (0.12 μg/g oil), and a significantly high amount of β-tocopherol (3.85 μg/g oil). It is a source of zinc and magnesium and contains safe levels of heavy metals. Based on these nutritional properties, the Indonesian sago grub can be considered as a good source of nutrients, and its propagation and utilization should be encouraged especially in other areas of Indonesia and maybe in neighboring countries where they are also endemic, and where malnutrition is prevalent. The consumption of edible insects should be considered as a component of dietary diversificationa sustainable way of alleviating the nutritional status of the population.
Ernährung & Medizin, 2018
ZusammenfassungWenn es um gesunde Ernährung und dabei ganz besonders um Vitamine geht, so wird im... more ZusammenfassungWenn es um gesunde Ernährung und dabei ganz besonders um Vitamine geht, so wird immer wieder darauf hingewiesen: „Wir brauchen keine (zusätzlichen) Vitamine, wir haben genug Obst und Gemüse!“ Beides ist nicht wirklich richtig! Natürlich brauchen wir Vitamine und wir haben durchaus auch genügend Obst und Gemüse. Allerdings sind Obst und Gemüse nicht alleine ausreichend, wenn es um die Versorgung mit Vitaminen geht!
Diätetik und Arteriosklerose, 1993
Under nutrition and food insecurity are major problems faced by most of the developing countries ... more Under nutrition and food insecurity are major problems faced by most of the developing countries including Tanzania. Approximately 42% of children below five years of age are stunted as a result of chronic undernutrition. Vitamin and mineral deficiencies are also very high where by about 59% and 34% of children below five years are iron and vitamin A deficient respectively and 48% of women are iodine deficient (National Bureau of Statistics [NBS] & ICF Macro, 2010). Foods with high nutrient content (vegetables and fruits) are difficult to find in the poorer rural areas during the dry seasons. Moreover rural households are affected with increasing food prices due to their low purchasing power (Adekunle, 2013). During this time, most people in rural areas are dependent on staple foods with little diversity.
Current Developments in Nutrition, 2019
Objectives Despite the availability of effective antimicrobials, tuberculosis (TB) remains as a p... more Objectives Despite the availability of effective antimicrobials, tuberculosis (TB) remains as a public health threat globally. There is a need for simple and inexpensive strategies to improve the treatment outcomes.The objective of our study was to deal with the potential use of vitamin D2 derived from sun-exposed oyster mushroom as adjunctive therapy to standard anti-TB treatment Methods Randomized controlled trial was conducted on 64 pulmonary TB patients (32 assigned to intervention and 32 assigned to control) in North Shewa, Ethiopia. Intervention group was provided with a sandwich prepared from sun-exposed oyster mushroom containing 146 µg (5840 IU) vitamin D2 continuously from Monday to Friday during the first 16 weeks of anti-TB treatment. Blood and sputum specimens were taken at the beginning and end of the study. The primary outcomes were changes in vitamin D status, clinical improvements (assessed by TB score and Karnofsky performance status scale) and immunologic response...
Zeitschrift für Phytotherapie, 2019
Clinical Interventions in Aging, 2018
Purpose: Despite some reports of high prevalence of thiamine deficiency in elderly people, the re... more Purpose: Despite some reports of high prevalence of thiamine deficiency in elderly people, the reported prevalence is controversial mainly due to the methods used in assessing thiamin concentrations. In this study, we sought to investigate the prevalence of vitamin B1 deficiency, using the high-performance liquid chromatography (HPLC) method, among older hospitalized patients. Patients and methods: This cross-sectional study retrospectively analyzed the results of routine measurements of vitamin B1 of 238 older patients who were consecutively hospitalized to a geriatric acute care ward. Whole blood vitamin B1 concentrations were measured using the HPLC method at hospital admission, and the whole blood vitamin B1 level of ,20 ng/mL was considered as deficiency. Results: Of 238 patients, with a mean age of 82.1±7.1 years, 63% of patients were women. In total, the mean whole blood vitamin B1 level was 66.1±24.8 ng/mL (range 29.5-215 ng/mL), indicating no vitamin B1 deficiency in the entire population. In addition, no significant differences in the mean whole blood vitamin B1 concentrations between sexes were observed (P=0.356). Conclusion: This study indicates that the mean whole blood vitamin B1 concentrations using the HPLC method were within the normal range in older hospitalized patients suggesting that thiamine deficiency appears to be rather uncommon among these patients.
British Journal of Cancer, 1989
International Journal of Obesity, 2004
Critical care (London, England), Jan 27, 2014
The use of vitamin C against different diseases has been controversially and emotionally discusse... more The use of vitamin C against different diseases has been controversially and emotionally discussed since Linus Pauling published his cancer studies. In vitro and animal studies showed promising results and explained the impact of vitamin C, particularly in cases with endothelial dysfunction. Indeed, studies (reviewed in this issue of Critical Care by Oudemans-van Straaten and colleagues) using high-dose vitamin C and the parenteral route of application seem to be more successful than oral vitamin C delivery.
Cancer research, Jan 15, 1988
BA-HAN-1C is a clonal rat rhabdomyosarcoma cell line composed of proliferating mononuclear cells,... more BA-HAN-1C is a clonal rat rhabdomyosarcoma cell line composed of proliferating mononuclear cells, which partly fuse to terminally differentiated postmitotic myotube-like giant cells. The exposure to retinoic acid in vitro resulted in time- and dose-dependent changes of both cell differentiation and cell growth. The mononuclear cells revealed bundles of newly formed thick and thin myofilaments, never observed in untreated cultures, and exhibited signs of contact inhibition. In addition, there was a statistically significant increase (P less than 0.001) in the number of terminally differentiated postmitotic myotube-like giant cells and in the creatine kinase activity (P less than 0.05) which was used as a biochemical differentiation marker. At the same time cell growth was significantly inhibited (P less than 0.001) in vitro and a decrease in plating efficiency, as well as in saturation density, was observed. These data demonstrate that retinoic acid can suppress cell growth and simul...