vojko didanovic | University of Ljubljana (original) (raw)
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Papers by vojko didanovic
Slovenian Medical Journal, 2010
Background: Orientation in space is of cardinal importance in surgery. In presurgical preparation... more Background: Orientation in space is of cardinal importance in surgery. In presurgical preparation surgeons make use of various virtual three-dimensional simulations, and since the beginning of 1990’s physical 3-d models made by a rapid prototyping technique have been employed. Conclusions: At the Clinical Department of Oral and Maxillofacial Surgery of the University Medical Centre in Ljubljana physical threedimensional models have been used since the beginning of 2007. We have done 120 virtual and 45 physical models, for the most demanding traumatological and oncological reconstructions. In this article, two cases of their usage are introduced.
Case Reports in Plastic Surgery and Hand Surgery, 2019
A 52-Year-old woman underwent a two-stage total nose reconstruction for complete nasal defect due... more A 52-Year-old woman underwent a two-stage total nose reconstruction for complete nasal defect due to skin cancer. In the 1 st stage, innervated osteocutaneous radial forearm flap ("Neo nose") was raised with the help of a 3D template. In the 2 nd stage, well vascularised "Neo-nose" was transferred to the face and covered with pre-expanded forehead flap.
Ear, Nose & Throat Journal, 2007
Radiology and Oncology, 2018
Background Among the diseases of oral mucosa, malignant tumors are the most dangerous, but not th... more Background Among the diseases of oral mucosa, malignant tumors are the most dangerous, but not the most common lesions that might appear in the oral cavity. Since most of the studies are focused on the detection of cancer in the oral cavity, we were interested in detecting the frequency of benign changes of the oral mucosa in Slovene population. Oral mucosal lesions are important pointer of oral health and quality of life, especially in elderly. The prevalence of oral mucosal lesions, together with information on the risk habits associated with oral health, such as tobacco and alcohol use, can help in planning future oral health studies and screening programs. Patients and methods Survey upon oral mucosal lesions was conducted during the national project for oral cancer screening in spring 2017 in the Slovenia in which more than 50% of dentists participated and 2395 patients (904 men and 1491 women) were included. Results Clinical examination, which was conducted according to the WH...
Oral Oncology Supplement, 2005
Introduction: There is no consensus about tile management of the clinically negative neck in pati... more Introduction: There is no consensus about tile management of the clinically negative neck in patients with head and neck cancer. The aim of this study was to ec-ahiate lymphatic mapping combined with attenuation corrected SPECT imaging for sentinel node biopsy. Materials and Methods: 40 patients with T1/T2 cN0 squamous cell carcmonla of tile oral cavity underwent pre-operatlve sentinel node Imaging. Techhnetmm (99mTc)-rhenium colloid was injected perl~morally in the submucosa. A dual head galnma camera with 90 degrees detector angulatlon was used for acqmsltlon of planar scmtlgraphy images as well as attenuated corrected SPECT images. Sentinel node biopsy was performed lnmledlately after the pro cesslng of tile sclntlgraphlc mlages. Patent Blue Dye was used m conlbmatlon with a hand held gamma probe to locate the sentinel nodes. Hlstologic exammahon included mulhstep sectioning followed by nnmmao hlsto chemistry. Results: 147 sentinel nodes were harvested m 39/40 patients with a median of 4 sen~lel nodes per patient Sentinel node Nopsy ldenhfied nodal dmease in 14/40 patients. Three patients dec-eloped nodal disease during follow-up. Three dec-eloped a metastasis m level I. In two of these patients the no des were not located due to scatter from the primary mmour. The patients were number 5 and 6 in our series. In patient number 4 no sentinel node was found at sclntlgraphy. The sentinel node was later ldenhfied in a review of the SPECT-scan. Conelus|on: The sentinel node technique is an accurate tool for staging small sqnamous cell carcinomas of the oral cavity. Identification of sentinel nodes close to the primary tumour contumes to be problematic. Failure of ldenhfiCatlon can certainly be clue to a "leanmag curve'-problem for both surgeon as well nuclear physician. SPECT mmgmg combined with peroperatlve ultrasonography can unprove the identification.
Oral Oncology Supplement, 2007
Wiener klinische Wochenschrift, 2004
First branchial cleft anomaly is a rare condition that is often misdiagnosed and falsely mistreat... more First branchial cleft anomaly is a rare condition that is often misdiagnosed and falsely mistreated before complete and definitive surgical treatment. Its origin is uncertain and the presence of ectodermal and sometimes also mesodermal elements has led some authors to the conclusion that it represents buried nests of cells forming the first branchial cleft and the underlying mesoderm. First branchial cleft anomaly can be presented as a cystic lesion, fistula or sinus extending towards the membranous external ear canal. The sinus tract runs through the parotid gland in close association with the facial nerve. There is no imaging method capable of identifying a first branchial cleft anomaly with certainty. The danger of facial nerve injury during surgery and the failure to identify the sinus tract running to the external ear canal are the main reasons for incomplete excision. The facial nerve must be identified and preserved and the lesion completely excised. Facial nerve injury is mo...
European Radiology, 2008
Our purpose was to determine the repeatability of squamous cell cancer in head and neck (SCCHN) a... more Our purpose was to determine the repeatability of squamous cell cancer in head and neck (SCCHN) and muscle tissue vascularity measurements as well as the inter- and intra-observer agreement using dynamic contrast-enhanced (DCE) multi-detector CT (MDCT). Twelve patients with histologically proven SCCHN were twice examined within 46 h. Measurement error and repeatability were assessed for each of the four functional parameters using the Bland-Altman plots. Two independent observers recorded the vascularity values of the tumor tissue; inter- and intra-observer agreement was assessed using the Bland-Altman plot analysis and intraclass correlation coefficients. For the tumor, the mean difference (95% limits of agreement) was 0.40 ml/min/100 g tissue (-6.80, 9.60); 0.01 (-0.96, 0.97) ml/100 g tissue; 0.20 (-1.80, 2.30) s; and 0.40 (-2.00, 2.80) ml/min/100 g tissue for BF, BV, MTT, and PS, respectively. For the muscle, the mean difference (95% limits of agreement) was -0.18 (-1.70, 1.35), 0.04 (-1.17, 1.35), -0.10 (-5.80, 5.60), and -0.10 (-2.20, 2.00), respectively. Measurement changes of at least +/-8%, 30%, 36%, and 13% were found to be significant for BF, BV, MTT, and PS, respectively. There was better intra- than inter-observer agreement.
Acta Neurochirurgica, 2006
Skull Base, 2007
Objective: To present the case of a rare tumor in the sphenoidoclival area and discuss potential ... more Objective: To present the case of a rare tumor in the sphenoidoclival area and discuss potential pitfalls in diagnosis and management. Design: Case report with literature review. Setting: Tertiary referral center. Case Summary: Our patient presented with headache, vertigo, vision problems, and feeling of pressure in the central segment of the face. MR and CT showed a lesion in the body of the sphenoid, with signs of bone destruction and irregular borders. Differential diagnosis included intraosseous meningioma, chordoma, and inflammatory process. Results: Endoscopic/microscopic transnasal approach was performed to reach clival bone and to biopsy the tumor. Histopathological examination showed intraosseous lipoma. Conclusion: Intraosseous lipoma is a rare tumor, or more accurately a hamartoma, and is usually found in the calcaneus or in the proximal femur. It is even rarer in the skull base. Usually it does not present any symptoms and is an incidental finding during imaging for other symptoms. As a rule it runs an indolent course and does not require any treatment. Since no definitive diagnosis can be made only on the basis of imaging (CT and MRI), it requires an open biopsy that if possible should be made in accordance with the principles of minimally invasive surgery.
Slovenian Medical Journal, 2010
Background: Orientation in space is of cardinal importance in surgery. In presurgical preparation... more Background: Orientation in space is of cardinal importance in surgery. In presurgical preparation surgeons make use of various virtual three-dimensional simulations, and since the beginning of 1990’s physical 3-d models made by a rapid prototyping technique have been employed. Conclusions: At the Clinical Department of Oral and Maxillofacial Surgery of the University Medical Centre in Ljubljana physical threedimensional models have been used since the beginning of 2007. We have done 120 virtual and 45 physical models, for the most demanding traumatological and oncological reconstructions. In this article, two cases of their usage are introduced.
Case Reports in Plastic Surgery and Hand Surgery, 2019
A 52-Year-old woman underwent a two-stage total nose reconstruction for complete nasal defect due... more A 52-Year-old woman underwent a two-stage total nose reconstruction for complete nasal defect due to skin cancer. In the 1 st stage, innervated osteocutaneous radial forearm flap ("Neo nose") was raised with the help of a 3D template. In the 2 nd stage, well vascularised "Neo-nose" was transferred to the face and covered with pre-expanded forehead flap.
Ear, Nose & Throat Journal, 2007
Radiology and Oncology, 2018
Background Among the diseases of oral mucosa, malignant tumors are the most dangerous, but not th... more Background Among the diseases of oral mucosa, malignant tumors are the most dangerous, but not the most common lesions that might appear in the oral cavity. Since most of the studies are focused on the detection of cancer in the oral cavity, we were interested in detecting the frequency of benign changes of the oral mucosa in Slovene population. Oral mucosal lesions are important pointer of oral health and quality of life, especially in elderly. The prevalence of oral mucosal lesions, together with information on the risk habits associated with oral health, such as tobacco and alcohol use, can help in planning future oral health studies and screening programs. Patients and methods Survey upon oral mucosal lesions was conducted during the national project for oral cancer screening in spring 2017 in the Slovenia in which more than 50% of dentists participated and 2395 patients (904 men and 1491 women) were included. Results Clinical examination, which was conducted according to the WH...
Oral Oncology Supplement, 2005
Introduction: There is no consensus about tile management of the clinically negative neck in pati... more Introduction: There is no consensus about tile management of the clinically negative neck in patients with head and neck cancer. The aim of this study was to ec-ahiate lymphatic mapping combined with attenuation corrected SPECT imaging for sentinel node biopsy. Materials and Methods: 40 patients with T1/T2 cN0 squamous cell carcmonla of tile oral cavity underwent pre-operatlve sentinel node Imaging. Techhnetmm (99mTc)-rhenium colloid was injected perl~morally in the submucosa. A dual head galnma camera with 90 degrees detector angulatlon was used for acqmsltlon of planar scmtlgraphy images as well as attenuated corrected SPECT images. Sentinel node biopsy was performed lnmledlately after the pro cesslng of tile sclntlgraphlc mlages. Patent Blue Dye was used m conlbmatlon with a hand held gamma probe to locate the sentinel nodes. Hlstologic exammahon included mulhstep sectioning followed by nnmmao hlsto chemistry. Results: 147 sentinel nodes were harvested m 39/40 patients with a median of 4 sen~lel nodes per patient Sentinel node Nopsy ldenhfied nodal dmease in 14/40 patients. Three patients dec-eloped nodal disease during follow-up. Three dec-eloped a metastasis m level I. In two of these patients the no des were not located due to scatter from the primary mmour. The patients were number 5 and 6 in our series. In patient number 4 no sentinel node was found at sclntlgraphy. The sentinel node was later ldenhfied in a review of the SPECT-scan. Conelus|on: The sentinel node technique is an accurate tool for staging small sqnamous cell carcinomas of the oral cavity. Identification of sentinel nodes close to the primary tumour contumes to be problematic. Failure of ldenhfiCatlon can certainly be clue to a "leanmag curve'-problem for both surgeon as well nuclear physician. SPECT mmgmg combined with peroperatlve ultrasonography can unprove the identification.
Oral Oncology Supplement, 2007
Wiener klinische Wochenschrift, 2004
First branchial cleft anomaly is a rare condition that is often misdiagnosed and falsely mistreat... more First branchial cleft anomaly is a rare condition that is often misdiagnosed and falsely mistreated before complete and definitive surgical treatment. Its origin is uncertain and the presence of ectodermal and sometimes also mesodermal elements has led some authors to the conclusion that it represents buried nests of cells forming the first branchial cleft and the underlying mesoderm. First branchial cleft anomaly can be presented as a cystic lesion, fistula or sinus extending towards the membranous external ear canal. The sinus tract runs through the parotid gland in close association with the facial nerve. There is no imaging method capable of identifying a first branchial cleft anomaly with certainty. The danger of facial nerve injury during surgery and the failure to identify the sinus tract running to the external ear canal are the main reasons for incomplete excision. The facial nerve must be identified and preserved and the lesion completely excised. Facial nerve injury is mo...
European Radiology, 2008
Our purpose was to determine the repeatability of squamous cell cancer in head and neck (SCCHN) a... more Our purpose was to determine the repeatability of squamous cell cancer in head and neck (SCCHN) and muscle tissue vascularity measurements as well as the inter- and intra-observer agreement using dynamic contrast-enhanced (DCE) multi-detector CT (MDCT). Twelve patients with histologically proven SCCHN were twice examined within 46 h. Measurement error and repeatability were assessed for each of the four functional parameters using the Bland-Altman plots. Two independent observers recorded the vascularity values of the tumor tissue; inter- and intra-observer agreement was assessed using the Bland-Altman plot analysis and intraclass correlation coefficients. For the tumor, the mean difference (95% limits of agreement) was 0.40 ml/min/100 g tissue (-6.80, 9.60); 0.01 (-0.96, 0.97) ml/100 g tissue; 0.20 (-1.80, 2.30) s; and 0.40 (-2.00, 2.80) ml/min/100 g tissue for BF, BV, MTT, and PS, respectively. For the muscle, the mean difference (95% limits of agreement) was -0.18 (-1.70, 1.35), 0.04 (-1.17, 1.35), -0.10 (-5.80, 5.60), and -0.10 (-2.20, 2.00), respectively. Measurement changes of at least +/-8%, 30%, 36%, and 13% were found to be significant for BF, BV, MTT, and PS, respectively. There was better intra- than inter-observer agreement.
Acta Neurochirurgica, 2006
Skull Base, 2007
Objective: To present the case of a rare tumor in the sphenoidoclival area and discuss potential ... more Objective: To present the case of a rare tumor in the sphenoidoclival area and discuss potential pitfalls in diagnosis and management. Design: Case report with literature review. Setting: Tertiary referral center. Case Summary: Our patient presented with headache, vertigo, vision problems, and feeling of pressure in the central segment of the face. MR and CT showed a lesion in the body of the sphenoid, with signs of bone destruction and irregular borders. Differential diagnosis included intraosseous meningioma, chordoma, and inflammatory process. Results: Endoscopic/microscopic transnasal approach was performed to reach clival bone and to biopsy the tumor. Histopathological examination showed intraosseous lipoma. Conclusion: Intraosseous lipoma is a rare tumor, or more accurately a hamartoma, and is usually found in the calcaneus or in the proximal femur. It is even rarer in the skull base. Usually it does not present any symptoms and is an incidental finding during imaging for other symptoms. As a rule it runs an indolent course and does not require any treatment. Since no definitive diagnosis can be made only on the basis of imaging (CT and MRI), it requires an open biopsy that if possible should be made in accordance with the principles of minimally invasive surgery.