Antonietta Pepe | Università della Basilicata (original) (raw)

Papers by Antonietta Pepe

Chemistry: A European Journal, Jan 27, 2017

Synthetic (glyco-)peptides inspired by proteins able to self-assemble are appealing biomaterials ... more Synthetic (glyco-)peptides inspired by proteins able to self-assemble are appealing biomaterials in the field of tissue engineering and regenerative medicine. Herein for the first time, taking advantage of thiol-ene chemistry coupled to Solid Phase Peptide Synthesis, a self-assembling peptide inspired by elastin protein was bioconjugated to three carbohydrates in order to obtain the corresponding glycopeptides. They were studied at molecular and supramolecular level. The results show that the carbohydrate influences the molecular conformation of the glycopeptide and its self-aggregation properties as well. As future perspective, the results could enable us to tune the final self-aggregation properties of the glycopeptide by changing the sugar moiety.

ACS applied polymer materials, Jan 20, 2023

Coatings, Sep 29, 2022

This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY

Chemistry: A European Journal, Jan 27, 2017

Synthetic (glyco-)peptides inspired by proteins able to self-assemble are appealing biomaterials ... more Synthetic (glyco-)peptides inspired by proteins able to self-assemble are appealing biomaterials in the field of tissue engineering and regenerative medicine. Herein for the first time, taking advantage of thiol-ene chemistry coupled to Solid Phase Peptide Synthesis, a self-assembling peptide inspired by elastin protein was bioconjugated to three carbohydrates in order to obtain the corresponding glycopeptides. They were studied at molecular and supramolecular level. The results show that the carbohydrate influences the molecular conformation of the glycopeptide and its self-aggregation properties as well. As future perspective, the results could enable us to tune the final self-aggregation properties of the glycopeptide by changing the sugar moiety.

ACS applied polymer materials, Jan 20, 2023

Coatings, Sep 29, 2022

This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY