Franz Moggi | University of Bern (original) (raw)

Papers by Franz Moggi

BACKGROUND There is a lack of studies on internet-based interventions in inpatient settings. This... more BACKGROUND There is a lack of studies on internet-based interventions in inpatient settings. This is especially true for studies of internet-based interventions in acute psychiatric inpatient care. Internet-based interventions in this specific setting may provide benefits such as patient empowerment and overall improved treatment outcomes. However, there may also be specific barriers to their implementation that are unique due to the complexity of acute psychiatric inpatient care. OBJECTIVE The aim of this study is to examine the feasibility and preliminary evidence for effectiveness of a web-based emotion regulation intervention provided as an add-on to acute psychiatric inpatient care. METHODS The goal is to randomly allocate 60 patients with a range of different diagnoses in a 1:1 ratio to either treatment as usual (TAU), which consists of acute psychiatric inpatient treatment, or to the intervention group, which will receive TAU plus access to a web-based intervention that focus...

Psychiatrische Praxis, 2021

Zusammenfassung Ziel der Studie Das Zusammenhangsmuster 26 allgemeiner Wirkfaktoren wurde mit dem... more Zusammenfassung Ziel der Studie Das Zusammenhangsmuster 26 allgemeiner Wirkfaktoren wurde mit dem Ziel untersucht, die Debatte um Wirkmechanismen der Psychotherapie mit empirisch abgeleiteten Sekundärfaktoren (globale allgemeine Wirkfaktoren) konzeptuell zu erweitern und gleichzeitig Aspekte der Reliabilität und Validität eines neuen Instruments zur Erfassung allgemeiner Wirkfaktoren zu prüfen. Methodik Die Aktivierung allgemeiner Wirkfaktoren wurde mit dem Wochenerfahrungsbogen (WEB) bei 502 Patientinnen und Patienten in teil- oder vollstationärer psychotherapeutischer Behandlung erhoben. Die Faktorenstruktur des WEB wurde anhand einer explorativen Faktorenanalyse ermittelt und mit konfirmatorischen Faktorenanalysen geprüft. Ergebnisse Die vier Faktoren Bewältigung, Therapeutische Allianz, Kognitive Integration und Affektive Verarbeitung erklärten 59,8 % der Gesamtvarianz. Konfirmatorische Faktorenanalysen der teil- und vollstationären Stichproben unterstützten diese Faktorenstrukt...

Suchtmedizin, 2019

Kapitel zu Begriffsbestimmung, Epidemiologie, kritische Diskussion zu Studienmethoden sowie zu ps... more Kapitel zu Begriffsbestimmung, Epidemiologie, kritische Diskussion zu Studienmethoden sowie zu psychosoziale und pharmakologische Behandlung

Co-occurring Addictive and Psychiatric Disorders, 2014

Although research and clinical interventions for patients with dual disorders have been described... more Although research and clinical interventions for patients with dual disorders have been described since as early as the 1980s, the day-to-day treatment of these patients remains problematic and challenging in many countries. Throughout this book, many approaches and possible pathways have been outlined. Based upon these experiences, some key points can be extracted in order to guide to future developments. (1) New diagnostic approaches are warranted when dealing with patients who have multiple problems, given the limitations of the current categorical systems. (2) Greater emphasis should be placed on secondary prevention and early intervention for children and adolescents at an increased risk of later-life dual disorders. (3) Mental, addiction, and somatic care systems can be integrated, adopting a patient-focused approach to care delivery. (4) Recovery should be taken into consideration when defining treatment intervention and outcome goals. (5) It is important to reduce societal risk factors, such as poverty and early childhood adversity. (6) More resources are needed to provide adequate mental health care in the various countries. The development of European guidance initiatives would provide benefits in many of these areas, making it possible to ensure a more harmonized standard of care for patients with dual disorders.

Hintergrund: Wahrend eine Reihe von Studien zeigen konnte, dass Personen mit einer Aufmerksamkeit... more Hintergrund: Wahrend eine Reihe von Studien zeigen konnte, dass Personen mit einer Aufmerksamkeitsdefizit-/Hyperaktivitatsstorung (ADHS) eine relativ hohe Pravalenz von Storungen durch Substanzkonsum aufweisen, wurden kaum prospektive Langsschnittstudien zur Initialisierung bzw. Eskalation von Substanzkonsum durchgefuhrt. Diese Kohortenstudie untersucht den pradiktiven Wert von ADHS Symptomen fur den Verlauf von Substanzkonsum in einer reprasentativen Stichprobe junger Schweizer Manner. Methode: In der „Cohort Study on Substance Use Risk Factors“ (C-SURF) wurden 5’103 Manner im Alter von 20 Jahren mit dem Screening Instrument „ADHS self-report scale“ (ASRS-v1.1) zu ADHS Symptomen sowie mit verschiedenen Fragebogen zu Storungen des Sozialverhaltens und zu Substanzkonsum befragt (Baseline) und 15 Monate spater nachuntersucht (Nachbefragung). Verglichen wurden Manner, deren Screening positiv fur ADHS ausfiel (ADHS+), mit Mannern mit negativem ADHS Screening (ADHS-) einerseits zum Zeitp...

European Psychiatry, 1994

Clinical Psychology & Psychotherapy, May 19, 2023

ObjectiveA large body of literature discusses change mechanisms underlying psychotherapy with an ... more ObjectiveA large body of literature discusses change mechanisms underlying psychotherapy with an emphasis on common factors. The present study examined how different comprehensive common factors change over the course of therapy and whether this change was associated with clinical outcome at discharge.MethodThree hundred forty‐eight adults (mean age = 32.1, SD = 10.6; 64% female) attended a standardized 14‐week day‐clinic psychotherapy program. They provided longitudinal data on common factors based on weekly assessments. Additionally, pre‐ and post‐assessment questionnaires on clinical outcome were completed. Using multilevel modelling, we predicted common factors by time (week in therapy). Multiple linear regression models tested the association between changes in common factors and clinical outcome.ResultsThe common factor ‘Therapeutic Alliance’ was best fitted by linear growth models, whereas models for the common factors ‘Coping’, ‘Cognitive Integration’ and ‘Affective Processing’ indicated logarithmic changes over time. ‘Coping’, that is change in patients' ability to cope with their individual problems, was most closely linked with outcome.ConclusionsThe present study provides evidence for the changeability of common factors over the course of therapy as well as their specific contributions to psychotherapeutic progress.

Neuropsychobiology, 2022

Introduction: In individuals with alcohol use disorder (AUD), the brain areas underlying cue-indu... more Introduction: In individuals with alcohol use disorder (AUD), the brain areas underlying cue-induced reactions (e.g., cingulum, striatum, thalamus) and altered activation of these regions have been identified by functional neuroimaging. Neuronal responses to a complex alcohol-related context are yet to investigate. To better understand contextual effects as well as the interplay of cue-induced neural reactions and context exposure, the present study implemented an imagination procedure during functional magnetic resonance imaging (fMRI). Methods: Thirteen patients with AUD and 13 healthy controls completed two rounds of a cue-reactivity paradigm inside an MRI scanner. Two individualized imagination tasks were conducted before each of the two cue reactivity tasks. A 2 (group) × 2 (imagination) × 2 (picture-type) analysis of variance (ANOVA) was performed. Results: The ANOVA revealed a main effect for imagination with higher activation in bilateral thalamus and right caudate nucleus and an interaction effect between imagination and group in right thalamus and left caudate nucleus, due to the patient group reacting stronger during alcohol-related imagination. These structures are involved in relaying sensory information and habit learning. No main or interaction effects of picture type were observed. Conclusions: These results support the view that context effects alter the neural responses in thalamus and nucleus caudatus in patients with AUD, and that imagination tasks are suited to incorporate contextual influences in neurophysiological research designs. Future research needs to investigate whether the failure to observe a picture-type effect was due to limited statistical power and omission to individualize picture set, or whether an imagination procedure interferes with the evocation of picture-type effects.

Springer eBooks, 2007

When individuals vote, decide on what to wear or what to eat, they do not do so in a societal vac... more When individuals vote, decide on what to wear or what to eat, they do not do so in a societal vacuum; rather, their actions are influenced and affected by society’s values, trends, commercials, and campaigns. From our daily experience, it seems plausible that social and cognitive processes are intertwined. However, in the area of natural recovery research, decisional processes of

Behavioural Brain Research, Feb 1, 2021

Alcohol use disorder (AUD) is characterized by both impaired inhibitory control and heightened cu... more Alcohol use disorder (AUD) is characterized by both impaired inhibitory control and heightened cue reactivity, including enhanced craving and drinking urges in response to alcohol-related stimuli. The interaction between these two mechanisms is thought to be crucial in the maintenance of addiction and relapse. The present study used a newly developed alcohol-related Go/NoGo-task to investigate how exposure to alcohol-related cues affects neural processing of inhibitory control in subjects with AUD. Functional magnetic resonance imaging (fMRI) was recorded during performance of a Go/NoGo task, which incorporated alcohol-related and neutral stimuli as Go and NoGo trials in abstinent AUD patients and healthy controls (HC). AUD patients exhibited increased activation of a fronto-striatal-parietal network during successful response inhibition relative to HC. Within the AUD group, activation for alcohol-related (relative to neutral) inhibition was enhanced in regions including bilateral anterior cingulate cortex (ACC), right medial frontal and precentral gyri, and right putamen. Activation differences in the right ACC increased with subjective craving. These preliminary findings suggest that AUD patients need to recruit enhanced neuronal resources for successful inhibition. In parts of the inhibitory network, this hyperactivation is enhanced when inhibition takes place in an alcohol-related context. Activation in the ACC increased stronger in patients experiencing high craving, possibly because of an enhanced conflict. The task introduced here thus allows to investigate neural processing of alcohol-related inhibition in an AUD sample. The preliminary results suggest that exposure to alcohol-related cues intensifies the demand on an already challenged inhibitory system in recently abstinent patients with AUD.

European Psychiatry, Mar 1, 2016

IntroductionAdults with attention-deficit/hyperactivity disorder (ADHD) symptoms show higher prev... more IntroductionAdults with attention-deficit/hyperactivity disorder (ADHD) symptoms show higher prevalence rates for substance use disorders (SUD).ObjectivesFew longitudinal studies have been conducted to observe the course of substance use among adults with ADHD.AimsThis study examined the predictive value of ADHD symptoms during the course of substance use in a population sample.MethodsIn two waves data from a representative sample of 5103 Swiss men in their early 20s were collected (baseline and 15-month follow-up) in the longitudinal “Cohort Study on Substance Use Risk Factors” (C-SURF). ADHD symptoms and substance use were assessed using the adult ADHD Self-Report Scale (ASRS-v1.1) and self-administered SUD questionnaires, respectively. Individuals who screened positive for ADHD (ADHD+) were compared to those who screened negative (ADHD−).ResultsAt baseline, the 215 individuals in the ADHD+ group (4.2%) showed considerably higher prevalence and frequency of substance use and prevalence of alcohol, tobacco, and cannabis use disorders relative to the ADHD− group. While alcohol, tobacco, cannabis, and heroin use remained stable from baseline to follow-up, the ADHD+ group was more likely to begin using illicit drugs (i.e. amphetamines, speed, ecstasy, hallucinogens, and cocaine) and initiate nonmedical use of prescription drugs (i.e. stimulants/amphetamines, hypnotics, and tranquilizers) relative to the ADHD− group.ConclusionsYoung men with ADHD symptoms displayed more severe substance use patterns and were at a high risk of initiating drug use within 15 months. The identification of ADHD symptoms during early adulthood may be relevant in early interventions to lower the risk of drug use.Disclosure of interestThe author has not supplied his declaration of competing interest.

Internet interventions, Sep 1, 2023