Marcio Abrahão | Universidade Federal de São Paulo (UNIFESP) (original) (raw)

Papers by Marcio Abrahão

European Journal of Plastic Surgery, 1996

The analysis of the complications of the pectoralis major osteomyocutaneous flaps used for head a... more The analysis of the complications of the pectoralis major osteomyocutaneous flaps used for head and neck reconstruction and how to prevent them is the subject of this report. Ten patients with squamous cell carcinoma of the floor of the mouth who had undergone segmental glossectomy and mandibulectomy, radical uni-or bilateral cervical lymphadenectomy, and immediate reconstruction with the pectoralis major osteomyocutaneous flaps were evaluated. Neither partial nor total necrosis of the myocutaneous segment occurred in any patient but rib necrosis developed in five. An oral fistula occurred in four patients exposing the junction of the rib with the mandible. There were three cases of flap necrosis of the neck dissection. Two patients developed pneumothorax. The overall complication rate was 66.7%. Although this surgery requires major intraoral excision, the tumor is exophytic with previous infection and the patients' general condition debilitated, the incidence of complications is high. Despite the high morbidity, the pectoralis major myocutaneous flap remains a useful adjunct for head and neck reconstruction. The flap is versatile and for many patients repair with a free flap is impossible because of contraindications such as previous irradiation, problems with the vascular anastomoses, advanced age and poor general condition. It also aids in the surgical training of new specialists.

Brazilian journal of otorhinolaryngology

Acta cirúrgica brasileira / Sociedade Brasileira para Desenvolvimento Pesquisa em Cirurgia, 2010

To evaluate the influence of PRP addition on bone repair of circular defects created in irradiate... more To evaluate the influence of PRP addition on bone repair of circular defects created in irradiated tibiae of rats by histometric analysis. Sixty male Wistar rats had the right tibiae irradiated with 30 Gy. After 30 days monocortical defects were created and platelet-rich plasma was applied in 30 rats. In the control group defects were created but not filled. The animals were desanguinated after 4, 7, 14, 21, 56 and 84 days and the tibiae removed for histological processing. There was a tendency in the PRP group to increased bone neoformation from 14-days to 84-days; in the control group increased bone neoformation was not seen after 21 days or later. The addition of platelet-rich plasma had a beneficial effect in the initial cellular regeneration period and enhanced bone formation in later periods when compared to control.

Revista Brasileira De Otorrinolaringologia, 2009

... Murilo Catafesta Das Neves I ; Marcello Rosano II ; Flávio Carneiro Hojaij III ; Márcio Abrah... more ... Murilo Catafesta Das Neves I ; Marcello Rosano II ; Flávio Carneiro Hojaij III ; Márcio Abrahão IV ; Onivaldo Cervantes V ; Danielle Macellaro ... Além do mais, apesar de a técnica da tireoidectomia estar bem estabelecida com baixos índices de complicação, o mesmo não pode ...

Otolaryngology-head and Neck Surgery, 2004

Objectives: Emergency tracheotomy prior to total laryngectomy for laryngeal carcinoma has been as... more Objectives: Emergency tracheotomy prior to total laryngectomy for laryngeal carcinoma has been associated with peristomal recurrence. The aim of this study was to retrospectively analyze the peristomal recurrence and the variables presented in literature as risk factors for it.Methods: The charts of 83 patients submitted to total laryngectomy, from 1992 to 2002, were analyzed regarding the peristomal recurrence and the

Jornal Brasileiro de Patologia e Medicina Laboratorial, 2003

OBJETIVO: Revisão dos achados clinicopatológicos dos tumores de glândulas salivares diagnosticado... more OBJETIVO: Revisão dos achados clinicopatológicos dos tumores de glândulas salivares diagnosticados no período de 1980 a 1997 no Departamento de Patologia da Escola Paulista de Medicina da Universidade Federal de São Paulo (EPM/Unifesp). MÉTODO: ...

Revista De Saude Publica, 2008

Saúde bucal, práticas de higiene bucal e ocorrência de câncer da cavidade oral ABSTRACT OBJECTIVE... more Saúde bucal, práticas de higiene bucal e ocorrência de câncer da cavidade oral ABSTRACT OBJECTIVE: To assess the association between oral health and hygiene practices and oral cancer.

Revista Brasileira de Otorrinolaringologia, 2005

As a result of technology evolution and development, methods of voice evaluation have changed bot... more As a result of technology evolution and development, methods of voice evaluation have changed both in medical and speech and language pathology practice. To relate the results of perceptual evaluation, acoustic analysis and medical evaluation in the diagnosis of vocal and/or laryngeal affections of the population with vocal complaint. Clinical prospective. 29 people that attended vocal health protection campaign were evaluated. They were submitted to perceptual evaluation (AFPA), acoustic analysis (AA), indirect laryngoscopy (LI) and telelaryngoscopy (TL). Correlations between medical and speech language pathology evaluation methods were established, verifying possible statistical signification with the application of Fischer Exact Test. There were statistically significant results in the correlation between AFPA and LI, AFPA and TL, LI and TL. This research study conducted in a vocal health protection campaign presented correlations between speech language pathology evaluation and perceptual evaluation and clinical evaluation, as well as between vocal affection and/or laryngeal medical exams.

Brazilian Journal of Medical and Biological Research, 2005

Brazilian journal of otorhinolaryngology

As a result of technology evolution and development, methods of voice evaluation have changed bot... more As a result of technology evolution and development, methods of voice evaluation have changed both in medical and speech and language pathology practice. To relate the results of perceptual evaluation, acoustic analysis and medical evaluation in the diagnosis of vocal and/or laryngeal affections of the population with vocal complaint. Clinical prospective. 29 people that attended vocal health protection campaign were evaluated. They were submitted to perceptual evaluation (AFPA), acoustic analysis (AA), indirect laryngoscopy (LI) and telelaryngoscopy (TL). Correlations between medical and speech language pathology evaluation methods were established, verifying possible statistical signification with the application of Fischer Exact Test. There were statistically significant results in the correlation between AFPA and LI, AFPA and TL, LI and TL. This research study conducted in a vocal health protection campaign presented correlations between speech language pathology evaluation and ...

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2006

To assess obstructive sleep apnea (OSA) in patients undergoing supracricoid horizontal partial la... more To assess obstructive sleep apnea (OSA) in patients undergoing supracricoid horizontal partial laryngectomy (SCPL) or frontolateral vertical partial laryngectomy (VPL) for the treatment of laryngeal carcinoma and correlate it with age, body mass index, physical examination, and upper airway evaluation. A prospective study was carried out involving 22 patients between 50 and 80 years of age divided into 2 equal groups. The patients underwent SCPL and VPL, and were evaluated by anamnesis, otolaryngologic examinations, nasopharyngolaryngoscopy, and polysomnography. A significant direct correlation was observed between the apnea/hypopnea index (AHI) and age of the patients. An inversely proportional relation was found between glottic opening and AHI. The presence of OSA was 81% in SCPL and 91% in VPL. We observed a high incidence of OSA in patients undergoing SCPL and VPL.

Sao Paulo Medical Journal, 2000

Paranasal sinus cancer is considered rare, with an incidence of less than 1 per 100,000 per year,... more Paranasal sinus cancer is considered rare, with an incidence of less than 1 per 100,000 per year, with the frontal sinus being the primary site in only 0.3%. We report a case of adenocarcinoma arising in the frontal sinus. Case report. A 59-year-old woman, secretary, came in February 1998 with a 4-month history of low intensity frontal headache. She denied contact with wood dust. On examination a non-tender swelling was noted over her right forehead next to the medial aspect of the right orbit. CT scan showed a soft-tissue mass involving frontal sinus with intracranial invasion through the posterior wall. The anterior ethmoid sinus and the medial aspect of the right orbit were also involved. MRI demonstrated dural thickening in communication with the frontal mass. She underwent an en-bloc tumor resection by craniotomy including orbital clearance. Histology revealed an adenocarcinoma. After surgery she had tumor recurrence, and chemotherapy and radiotherapy were started resulting in partial improvement.

International Journal of Oral and Maxillofacial Surgery, 2011

International Journal of Oral and Maxillofacial Surgery, 2011

interarch space and antral pneumatization for prosthetics rehabilitation at the posterior edentul... more interarch space and antral pneumatization for prosthetics rehabilitation at the posterior edentulous maxillary segments. Surgical intrusion of the osteotomised block bone segment as a corticocancelouse block bone graft to sinus cavity resulted in an adequate interarch space and simultaneous vertical ridge augmentation in posterior maxillary ridge deficiency for surgical and prosthetic outcomes without need for harvesting bone from another site.

Cadernos de Saúde Pública, 2007

... Dirce Maria Lobo Marchioni 1 Regina Mara Fisberg 1 José Francisco de Góis Filho 2 Luiz Paulo ... more ... Dirce Maria Lobo Marchioni 1 Regina Mara Fisberg 1 José Francisco de Góis Filho 2 Luiz Paulo Kowalski 2 Marcos Brasilino de ... indivíduo dois anos antes da entrevista, somató-ria do número de porções dos itens alimentares consumidos, macrorregião de nascimento e es ...

Acta Cirurgica Brasileira, 2004

Brazilian Journal of Otorhinolaryngology, 2014

Introduction: Several methods have been proposed to improve operative success in renal hyperparat... more Introduction: Several methods have been proposed to improve operative success in renal hyperparathyroidism. Objective: To evaluate stereomicroscopy in parathyroid tissue selection for total parathyroidectomy with autotransplantation in secondary (SHPT)/tertiary (THPT) hyperparathyroidism.

Sleep and Breathing, 2013

Goiters cause a series of compressive symptoms, including dyspnea and dysphagia. There have been ... more Goiters cause a series of compressive symptoms, including dyspnea and dysphagia. There have been reports of the coexistence of this syndrome with obstructive sleep apnea (OSA). The objective of this study was to evaluate the prevalence of OSA in a group of patients with goiters. Twenty-four patients with a mean age of 52.7 ± 12.7 years, including five males (20.8 %) and 19 (79.2 %) females, who were diagnosed with euthyroid goiters with volumes exceeding 100 ml were consecutively selected. The protocol consisted of sleep questionnaires, physical examinations, and baseline polysomnography measurements. Patients were divided into two groups, OSA and NOSA (no OSA), and all findings were compared between the two groups. Of the studied patients, 70.8 % had OSA (p = 0.004). Regarding clinical parameters, age (p = 0.001), Epworth Sleepiness Scale scores (p = 0.039) and complaints of habitual snoring (p < 0.001) had higher values in the OSA group. Regarding physical examination parameters, body mass index (p = 0.012), neck circumference (p = 0.009) and the presence of tracheal compression (p = 0.021) had higher values in the OSA group. The polysomnographic parameters that were significantly different between the two groups were the greater apnea and hypopnea index per hour of sleep (p < 0.001) and the lower minimum oxyhemoglobin saturation in the OSA group (p = 0.011). There is a high prevalence of OSA in patients with goiters. The main findings that were associated with the presence of OSA are known clinical predictors of OSA and the presence of tracheal compression.

Sleep and Breathing, 2014

A large goiter can cause a series of compressive symptoms such as dyspnea and dysphagia, and prev... more A large goiter can cause a series of compressive symptoms such as dyspnea and dysphagia, and previous case reports have indicated the coexistence of obstructive sleep apnea syndrome (OSAS) in these patients. The aim of this study was to evaluate the impact of thyroidectomy on the control of OSAS in patients with large goiters. Twenty-four patients with euthyroid goiters larger than 100 ml were consecutively selected. Of these, 17 (70.8%) presented OSAS and formed the research group. The protocol consisted of sleep questionnaires, physical examination, and polysomnography in baseline and after 3 months of surgery. The average age of the patients was 58.3±9.9 years, and there were 5 (29.4%) males and 12 (70.6%) females. The significant findings in the postoperative period included a reduced neck circumference (p=0.041), reduced Epworth sleepiness score (p=0.025), decreased percentage of high-risk OSAS cases according to the Berlin questionnaire (p<0.001), and a tendency for a significant reduction in snoring (p=0.052). However, polysomnographic respiratory parameters showed no significant improvement after surgery. Despite the high prevalence of OSAS in patients with large goiters and the improvement of OSAS symptoms, thyroidectomy showed no significant impact on the polysomnographic parameters.

Sao Paulo Medical Journal, 2004

European Journal of Plastic Surgery, 1996

The analysis of the complications of the pectoralis major osteomyocutaneous flaps used for head a... more The analysis of the complications of the pectoralis major osteomyocutaneous flaps used for head and neck reconstruction and how to prevent them is the subject of this report. Ten patients with squamous cell carcinoma of the floor of the mouth who had undergone segmental glossectomy and mandibulectomy, radical uni-or bilateral cervical lymphadenectomy, and immediate reconstruction with the pectoralis major osteomyocutaneous flaps were evaluated. Neither partial nor total necrosis of the myocutaneous segment occurred in any patient but rib necrosis developed in five. An oral fistula occurred in four patients exposing the junction of the rib with the mandible. There were three cases of flap necrosis of the neck dissection. Two patients developed pneumothorax. The overall complication rate was 66.7%. Although this surgery requires major intraoral excision, the tumor is exophytic with previous infection and the patients' general condition debilitated, the incidence of complications is high. Despite the high morbidity, the pectoralis major myocutaneous flap remains a useful adjunct for head and neck reconstruction. The flap is versatile and for many patients repair with a free flap is impossible because of contraindications such as previous irradiation, problems with the vascular anastomoses, advanced age and poor general condition. It also aids in the surgical training of new specialists.

Brazilian journal of otorhinolaryngology

Acta cirúrgica brasileira / Sociedade Brasileira para Desenvolvimento Pesquisa em Cirurgia, 2010

To evaluate the influence of PRP addition on bone repair of circular defects created in irradiate... more To evaluate the influence of PRP addition on bone repair of circular defects created in irradiated tibiae of rats by histometric analysis. Sixty male Wistar rats had the right tibiae irradiated with 30 Gy. After 30 days monocortical defects were created and platelet-rich plasma was applied in 30 rats. In the control group defects were created but not filled. The animals were desanguinated after 4, 7, 14, 21, 56 and 84 days and the tibiae removed for histological processing. There was a tendency in the PRP group to increased bone neoformation from 14-days to 84-days; in the control group increased bone neoformation was not seen after 21 days or later. The addition of platelet-rich plasma had a beneficial effect in the initial cellular regeneration period and enhanced bone formation in later periods when compared to control.

Revista Brasileira De Otorrinolaringologia, 2009

... Murilo Catafesta Das Neves I ; Marcello Rosano II ; Flávio Carneiro Hojaij III ; Márcio Abrah... more ... Murilo Catafesta Das Neves I ; Marcello Rosano II ; Flávio Carneiro Hojaij III ; Márcio Abrahão IV ; Onivaldo Cervantes V ; Danielle Macellaro ... Além do mais, apesar de a técnica da tireoidectomia estar bem estabelecida com baixos índices de complicação, o mesmo não pode ...

Otolaryngology-head and Neck Surgery, 2004

Objectives: Emergency tracheotomy prior to total laryngectomy for laryngeal carcinoma has been as... more Objectives: Emergency tracheotomy prior to total laryngectomy for laryngeal carcinoma has been associated with peristomal recurrence. The aim of this study was to retrospectively analyze the peristomal recurrence and the variables presented in literature as risk factors for it.Methods: The charts of 83 patients submitted to total laryngectomy, from 1992 to 2002, were analyzed regarding the peristomal recurrence and the

Jornal Brasileiro de Patologia e Medicina Laboratorial, 2003

OBJETIVO: Revisão dos achados clinicopatológicos dos tumores de glândulas salivares diagnosticado... more OBJETIVO: Revisão dos achados clinicopatológicos dos tumores de glândulas salivares diagnosticados no período de 1980 a 1997 no Departamento de Patologia da Escola Paulista de Medicina da Universidade Federal de São Paulo (EPM/Unifesp). MÉTODO: ...

Revista De Saude Publica, 2008

Saúde bucal, práticas de higiene bucal e ocorrência de câncer da cavidade oral ABSTRACT OBJECTIVE... more Saúde bucal, práticas de higiene bucal e ocorrência de câncer da cavidade oral ABSTRACT OBJECTIVE: To assess the association between oral health and hygiene practices and oral cancer.

Revista Brasileira de Otorrinolaringologia, 2005

As a result of technology evolution and development, methods of voice evaluation have changed bot... more As a result of technology evolution and development, methods of voice evaluation have changed both in medical and speech and language pathology practice. To relate the results of perceptual evaluation, acoustic analysis and medical evaluation in the diagnosis of vocal and/or laryngeal affections of the population with vocal complaint. Clinical prospective. 29 people that attended vocal health protection campaign were evaluated. They were submitted to perceptual evaluation (AFPA), acoustic analysis (AA), indirect laryngoscopy (LI) and telelaryngoscopy (TL). Correlations between medical and speech language pathology evaluation methods were established, verifying possible statistical signification with the application of Fischer Exact Test. There were statistically significant results in the correlation between AFPA and LI, AFPA and TL, LI and TL. This research study conducted in a vocal health protection campaign presented correlations between speech language pathology evaluation and perceptual evaluation and clinical evaluation, as well as between vocal affection and/or laryngeal medical exams.

Brazilian Journal of Medical and Biological Research, 2005

Brazilian journal of otorhinolaryngology

As a result of technology evolution and development, methods of voice evaluation have changed bot... more As a result of technology evolution and development, methods of voice evaluation have changed both in medical and speech and language pathology practice. To relate the results of perceptual evaluation, acoustic analysis and medical evaluation in the diagnosis of vocal and/or laryngeal affections of the population with vocal complaint. Clinical prospective. 29 people that attended vocal health protection campaign were evaluated. They were submitted to perceptual evaluation (AFPA), acoustic analysis (AA), indirect laryngoscopy (LI) and telelaryngoscopy (TL). Correlations between medical and speech language pathology evaluation methods were established, verifying possible statistical signification with the application of Fischer Exact Test. There were statistically significant results in the correlation between AFPA and LI, AFPA and TL, LI and TL. This research study conducted in a vocal health protection campaign presented correlations between speech language pathology evaluation and ...

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2006

To assess obstructive sleep apnea (OSA) in patients undergoing supracricoid horizontal partial la... more To assess obstructive sleep apnea (OSA) in patients undergoing supracricoid horizontal partial laryngectomy (SCPL) or frontolateral vertical partial laryngectomy (VPL) for the treatment of laryngeal carcinoma and correlate it with age, body mass index, physical examination, and upper airway evaluation. A prospective study was carried out involving 22 patients between 50 and 80 years of age divided into 2 equal groups. The patients underwent SCPL and VPL, and were evaluated by anamnesis, otolaryngologic examinations, nasopharyngolaryngoscopy, and polysomnography. A significant direct correlation was observed between the apnea/hypopnea index (AHI) and age of the patients. An inversely proportional relation was found between glottic opening and AHI. The presence of OSA was 81% in SCPL and 91% in VPL. We observed a high incidence of OSA in patients undergoing SCPL and VPL.

Sao Paulo Medical Journal, 2000

Paranasal sinus cancer is considered rare, with an incidence of less than 1 per 100,000 per year,... more Paranasal sinus cancer is considered rare, with an incidence of less than 1 per 100,000 per year, with the frontal sinus being the primary site in only 0.3%. We report a case of adenocarcinoma arising in the frontal sinus. Case report. A 59-year-old woman, secretary, came in February 1998 with a 4-month history of low intensity frontal headache. She denied contact with wood dust. On examination a non-tender swelling was noted over her right forehead next to the medial aspect of the right orbit. CT scan showed a soft-tissue mass involving frontal sinus with intracranial invasion through the posterior wall. The anterior ethmoid sinus and the medial aspect of the right orbit were also involved. MRI demonstrated dural thickening in communication with the frontal mass. She underwent an en-bloc tumor resection by craniotomy including orbital clearance. Histology revealed an adenocarcinoma. After surgery she had tumor recurrence, and chemotherapy and radiotherapy were started resulting in partial improvement.

International Journal of Oral and Maxillofacial Surgery, 2011

International Journal of Oral and Maxillofacial Surgery, 2011

interarch space and antral pneumatization for prosthetics rehabilitation at the posterior edentul... more interarch space and antral pneumatization for prosthetics rehabilitation at the posterior edentulous maxillary segments. Surgical intrusion of the osteotomised block bone segment as a corticocancelouse block bone graft to sinus cavity resulted in an adequate interarch space and simultaneous vertical ridge augmentation in posterior maxillary ridge deficiency for surgical and prosthetic outcomes without need for harvesting bone from another site.

Cadernos de Saúde Pública, 2007

... Dirce Maria Lobo Marchioni 1 Regina Mara Fisberg 1 José Francisco de Góis Filho 2 Luiz Paulo ... more ... Dirce Maria Lobo Marchioni 1 Regina Mara Fisberg 1 José Francisco de Góis Filho 2 Luiz Paulo Kowalski 2 Marcos Brasilino de ... indivíduo dois anos antes da entrevista, somató-ria do número de porções dos itens alimentares consumidos, macrorregião de nascimento e es ...

Acta Cirurgica Brasileira, 2004

Brazilian Journal of Otorhinolaryngology, 2014

Introduction: Several methods have been proposed to improve operative success in renal hyperparat... more Introduction: Several methods have been proposed to improve operative success in renal hyperparathyroidism. Objective: To evaluate stereomicroscopy in parathyroid tissue selection for total parathyroidectomy with autotransplantation in secondary (SHPT)/tertiary (THPT) hyperparathyroidism.

Sleep and Breathing, 2013

Goiters cause a series of compressive symptoms, including dyspnea and dysphagia. There have been ... more Goiters cause a series of compressive symptoms, including dyspnea and dysphagia. There have been reports of the coexistence of this syndrome with obstructive sleep apnea (OSA). The objective of this study was to evaluate the prevalence of OSA in a group of patients with goiters. Twenty-four patients with a mean age of 52.7 ± 12.7 years, including five males (20.8 %) and 19 (79.2 %) females, who were diagnosed with euthyroid goiters with volumes exceeding 100 ml were consecutively selected. The protocol consisted of sleep questionnaires, physical examinations, and baseline polysomnography measurements. Patients were divided into two groups, OSA and NOSA (no OSA), and all findings were compared between the two groups. Of the studied patients, 70.8 % had OSA (p = 0.004). Regarding clinical parameters, age (p = 0.001), Epworth Sleepiness Scale scores (p = 0.039) and complaints of habitual snoring (p < 0.001) had higher values in the OSA group. Regarding physical examination parameters, body mass index (p = 0.012), neck circumference (p = 0.009) and the presence of tracheal compression (p = 0.021) had higher values in the OSA group. The polysomnographic parameters that were significantly different between the two groups were the greater apnea and hypopnea index per hour of sleep (p < 0.001) and the lower minimum oxyhemoglobin saturation in the OSA group (p = 0.011). There is a high prevalence of OSA in patients with goiters. The main findings that were associated with the presence of OSA are known clinical predictors of OSA and the presence of tracheal compression.

Sleep and Breathing, 2014

A large goiter can cause a series of compressive symptoms such as dyspnea and dysphagia, and prev... more A large goiter can cause a series of compressive symptoms such as dyspnea and dysphagia, and previous case reports have indicated the coexistence of obstructive sleep apnea syndrome (OSAS) in these patients. The aim of this study was to evaluate the impact of thyroidectomy on the control of OSAS in patients with large goiters. Twenty-four patients with euthyroid goiters larger than 100 ml were consecutively selected. Of these, 17 (70.8%) presented OSAS and formed the research group. The protocol consisted of sleep questionnaires, physical examination, and polysomnography in baseline and after 3 months of surgery. The average age of the patients was 58.3±9.9 years, and there were 5 (29.4%) males and 12 (70.6%) females. The significant findings in the postoperative period included a reduced neck circumference (p=0.041), reduced Epworth sleepiness score (p=0.025), decreased percentage of high-risk OSAS cases according to the Berlin questionnaire (p<0.001), and a tendency for a significant reduction in snoring (p=0.052). However, polysomnographic respiratory parameters showed no significant improvement after surgery. Despite the high prevalence of OSAS in patients with large goiters and the improvement of OSAS symptoms, thyroidectomy showed no significant impact on the polysomnographic parameters.

Sao Paulo Medical Journal, 2004