Pio Liberatore | Università degli Studi di Foggia (original) (raw)

Papers by Pio Liberatore

Research paper thumbnail of Nasal High Frequency Oscillatory Ventilation for Respiratory Failure due to Respiratory Syncytial Virus Bronchiolitis: Case Report

American Journal of Perinatology Reports

The authors describe a case of acute respiratory failure due to severe bronchiolitis. During high... more The authors describe a case of acute respiratory failure due to severe bronchiolitis. During high-flow nasal cannula ventilation, the blood's high levels of hypercapnia had taken them to plan the sedation and the orotracheal intubation. However, before attempting intubation, a nasal high frequency oscillatory ventilation cycle was performed and it led to a marked improvement in the blood gas, avoiding in this way the invasive ventilation.

Research paper thumbnail of Nephrotic Syndrome Following H1N1 Influenza in a 3-Year-Old Boy

Iranian journal of pediatrics, 2012

The pandemic influenza A/H1N1, spread through the world in 2009, producing a serious epidemic in ... more The pandemic influenza A/H1N1, spread through the world in 2009, producing a serious epidemic in Italy. Complications are generally limited to patients at the extremes of age (<6 months or >65 years) and those with comorbid medical illness. The most frequent complications of influenza involve the respiratory system. A 3-year-old boy with a recent history of upper respiratory tract infection developed a nephrotic syndrome. Together with prednisone, furosemide and albumin bolus, a therapy with oseltamivir was started since the nasopharyngeal swab resulted positive for influenza A/H1N1. Clinical conditions and laboratory findings progressively improved during hospitalization, becoming normal during a 2 month follow up. The possibility of a renal involvement after influenza A/H1N1 infection should be considered.

Research paper thumbnail of Necrosis of mesenteric lymph nodes in Henoch–Schönlein purpura

Dear Sir, Henoch–Schönlein purpura (HSP) is the most common vasculitis of the pediatric age, most... more Dear Sir, Henoch–Schönlein purpura (HSP) is the most common vasculitis of the pediatric age, mostly occurring in children between 4 and 6 years [1]: this is a systemic disease related to IgA deposition in the capillaries and small-sized arteries of different organs [2], ...

Research paper thumbnail of Cardamom Ingestion as a Possible Cause of Hematuria

The Indian Journal of Pediatrics, 2011

Research paper thumbnail of Necrosis of mesenteric lymph nodes in Henoch–Schönlein purpura

Rheumatology International, 2012

Dear Sir, Henoch–Schönlein purpura (HSP) is the most common vasculitis of the pediatric age, most... more Dear Sir, Henoch–Schönlein purpura (HSP) is the most common vasculitis of the pediatric age, mostly occurring in children between 4 and 6 years [1]: this is a systemic disease related to IgA deposition in the capillaries and small-sized arteries of different organs [2], ...

Research paper thumbnail of Massive Proteinuria: A Possible Side Effect of Pyrantel Pamoate?

Renal Failure, 2011

Drug-induced renal injury represents a frequent clinical entity. The most common drugs associated... more Drug-induced renal injury represents a frequent clinical entity. The most common drugs associated with acute tubular necrosis are aminoglycosides, amphotericin B, radiocontrast agents, and cyclosporine, but no data exist about the potential renal toxicity due to anthelmintics administration. Anthelmintics are commonly considered quite safe agents, and side effects such as gastrointestinal, neurologic, hematologic, or hepatic injury have been only rarely described. We report a 4-year-old boy with persistent massive proteinuria without any other symptoms/signs suggesting nephrotic syndrome (NS). The only relevant anamnestic data was the administration of pyrantel pamoate due to oxyuriasis 7 days before the proteinuria development. The patient was affected by NS diagnosed 6 months before and treated with a 12-week course of corticosteroids. During follow-up, carried out at 3 and 6 months after discharge, he did not show further episodes of proteinuria, and no clinical symptoms/signs suggesting a relapse of NS were ever detected. Considering that the proteinuria observed in our patient spontaneously disappeared after 10 days without any treatment, apart from the interruption of the anthelmintic therapy, we would like to alert pediatricians about the possible occurrence of anthelmintics-related renal complications especially among predisposed patients and to perform a watchful waiting not considering the presence of even massive proteinuria as a certain sign of NS relapse.

Research paper thumbnail of Factitious disorders and Munchausen syndrome: The tip of the iceberg

Journal of Child Health Care, 2013

This population-based study evaluates the prevalence of factitious disorders, Münchausen syndrome... more This population-based study evaluates the prevalence of factitious disorders, Münchausen syndrome, and Münchausen syndrome by proxy in a clinical setting. All children referred to the Pediatric Unit of the Department of Pediatrics of the Catholic University Medical School (Agostino Gemelli Hospital) in Rome were recruited between November 2007 and March 2010. An experienced interdisciplinary team of medical professionals analyzed all suspected cases. A total of 751 patients were hospitalized. Factitious disorders were diagnosed in 14/751 patients, resulting in a prevalence of 1.8%. Three of 14 (21.4%) patients fulfilled the criteria for Münchausen syndrome. Münchausen syndrome by proxy was identified in four of 751 patients, resulting in a prevalence of 0.53%. The perpetrator was the mother in three of four of these cases. The epidemiological data obtained in this population-based study indicate that the prevalence of factitious disorders, Münchausen syndrome, and Münchausen syndrome by proxy is higher than previously observed. Moreover, early detection was possible thanks to the awareness of an expert interdisciplinary team. We suggest that physicians must consider the possibility of these diagnoses whenever there are discrepancies in a child&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39;s illness presentation.

Research paper thumbnail of Children left unattended in parked vehicles: a focus on recent italian cases and a review of literature

Italian Journal of Pediatrics, 2013

Research paper thumbnail of Atypical presentation of renal angiomyolipomas in a child with tuberous sclerosis complex

Iranian journal of pediatrics, 2011

Abstract: Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder with a birth... more Abstract: Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder with a birth incidence of 1: 6.000. It can virtually affect any organ system and all racial and ethnic groups. Clinical manifestations of TSC have variable penetrance. Many affected patients ...

Research paper thumbnail of Nasal High Frequency Oscillatory Ventilation for Respiratory Failure due to Respiratory Syncytial Virus Bronchiolitis: Case Report

American Journal of Perinatology Reports

The authors describe a case of acute respiratory failure due to severe bronchiolitis. During high... more The authors describe a case of acute respiratory failure due to severe bronchiolitis. During high-flow nasal cannula ventilation, the blood's high levels of hypercapnia had taken them to plan the sedation and the orotracheal intubation. However, before attempting intubation, a nasal high frequency oscillatory ventilation cycle was performed and it led to a marked improvement in the blood gas, avoiding in this way the invasive ventilation.

Research paper thumbnail of Nephrotic Syndrome Following H1N1 Influenza in a 3-Year-Old Boy

Iranian journal of pediatrics, 2012

The pandemic influenza A/H1N1, spread through the world in 2009, producing a serious epidemic in ... more The pandemic influenza A/H1N1, spread through the world in 2009, producing a serious epidemic in Italy. Complications are generally limited to patients at the extremes of age (<6 months or >65 years) and those with comorbid medical illness. The most frequent complications of influenza involve the respiratory system. A 3-year-old boy with a recent history of upper respiratory tract infection developed a nephrotic syndrome. Together with prednisone, furosemide and albumin bolus, a therapy with oseltamivir was started since the nasopharyngeal swab resulted positive for influenza A/H1N1. Clinical conditions and laboratory findings progressively improved during hospitalization, becoming normal during a 2 month follow up. The possibility of a renal involvement after influenza A/H1N1 infection should be considered.

Research paper thumbnail of Necrosis of mesenteric lymph nodes in Henoch–Schönlein purpura

Dear Sir, Henoch–Schönlein purpura (HSP) is the most common vasculitis of the pediatric age, most... more Dear Sir, Henoch–Schönlein purpura (HSP) is the most common vasculitis of the pediatric age, mostly occurring in children between 4 and 6 years [1]: this is a systemic disease related to IgA deposition in the capillaries and small-sized arteries of different organs [2], ...

Research paper thumbnail of Cardamom Ingestion as a Possible Cause of Hematuria

The Indian Journal of Pediatrics, 2011

Research paper thumbnail of Necrosis of mesenteric lymph nodes in Henoch–Schönlein purpura

Rheumatology International, 2012

Dear Sir, Henoch–Schönlein purpura (HSP) is the most common vasculitis of the pediatric age, most... more Dear Sir, Henoch–Schönlein purpura (HSP) is the most common vasculitis of the pediatric age, mostly occurring in children between 4 and 6 years [1]: this is a systemic disease related to IgA deposition in the capillaries and small-sized arteries of different organs [2], ...

Research paper thumbnail of Massive Proteinuria: A Possible Side Effect of Pyrantel Pamoate?

Renal Failure, 2011

Drug-induced renal injury represents a frequent clinical entity. The most common drugs associated... more Drug-induced renal injury represents a frequent clinical entity. The most common drugs associated with acute tubular necrosis are aminoglycosides, amphotericin B, radiocontrast agents, and cyclosporine, but no data exist about the potential renal toxicity due to anthelmintics administration. Anthelmintics are commonly considered quite safe agents, and side effects such as gastrointestinal, neurologic, hematologic, or hepatic injury have been only rarely described. We report a 4-year-old boy with persistent massive proteinuria without any other symptoms/signs suggesting nephrotic syndrome (NS). The only relevant anamnestic data was the administration of pyrantel pamoate due to oxyuriasis 7 days before the proteinuria development. The patient was affected by NS diagnosed 6 months before and treated with a 12-week course of corticosteroids. During follow-up, carried out at 3 and 6 months after discharge, he did not show further episodes of proteinuria, and no clinical symptoms/signs suggesting a relapse of NS were ever detected. Considering that the proteinuria observed in our patient spontaneously disappeared after 10 days without any treatment, apart from the interruption of the anthelmintic therapy, we would like to alert pediatricians about the possible occurrence of anthelmintics-related renal complications especially among predisposed patients and to perform a watchful waiting not considering the presence of even massive proteinuria as a certain sign of NS relapse.

Research paper thumbnail of Factitious disorders and Munchausen syndrome: The tip of the iceberg

Journal of Child Health Care, 2013

This population-based study evaluates the prevalence of factitious disorders, Münchausen syndrome... more This population-based study evaluates the prevalence of factitious disorders, Münchausen syndrome, and Münchausen syndrome by proxy in a clinical setting. All children referred to the Pediatric Unit of the Department of Pediatrics of the Catholic University Medical School (Agostino Gemelli Hospital) in Rome were recruited between November 2007 and March 2010. An experienced interdisciplinary team of medical professionals analyzed all suspected cases. A total of 751 patients were hospitalized. Factitious disorders were diagnosed in 14/751 patients, resulting in a prevalence of 1.8%. Three of 14 (21.4%) patients fulfilled the criteria for Münchausen syndrome. Münchausen syndrome by proxy was identified in four of 751 patients, resulting in a prevalence of 0.53%. The perpetrator was the mother in three of four of these cases. The epidemiological data obtained in this population-based study indicate that the prevalence of factitious disorders, Münchausen syndrome, and Münchausen syndrome by proxy is higher than previously observed. Moreover, early detection was possible thanks to the awareness of an expert interdisciplinary team. We suggest that physicians must consider the possibility of these diagnoses whenever there are discrepancies in a child&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39;s illness presentation.

Research paper thumbnail of Children left unattended in parked vehicles: a focus on recent italian cases and a review of literature

Italian Journal of Pediatrics, 2013

Research paper thumbnail of Atypical presentation of renal angiomyolipomas in a child with tuberous sclerosis complex

Iranian journal of pediatrics, 2011

Abstract: Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder with a birth... more Abstract: Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder with a birth incidence of 1: 6.000. It can virtually affect any organ system and all racial and ethnic groups. Clinical manifestations of TSC have variable penetrance. Many affected patients ...