Pascal Bovet | University of Lausanne (original) (raw)
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Papers by Pascal Bovet
International Journal of Epidemiology, 2013
PloS one, 2014
Cardiovascular diseases (CVD) mortality has been shown to follow a seasonal pattern. Several stud... more Cardiovascular diseases (CVD) mortality has been shown to follow a seasonal pattern. Several studies suggested several possible determinants of this pattern, including misclassification of causes of deaths. We aimed at assessing seasonality in overall, CVD, cancer and non-CVD/non-cancer mortality using data from 19 countries from different latitudes. Monthly mortality data were compiled from 19 countries, amounting to over 54 million deaths. We calculated ratios of the observed to the expected numbers of deaths in the absence of a seasonal pattern. Seasonal variation (peak to nadir difference) for overall and cause-specific (CVD, cancer or non-CVD/non-cancer) mortality was analyzed using the cosinor function model. Mortality from overall, CVD and non-CVD/non-cancer showed a consistent seasonal pattern. In both hemispheres, the number of deaths was higher than expected in winter. In countries close to the Equator the seasonal pattern was considerably lower for mortality from any caus...
... 1994;14;1553-1560 Arterioscler Thromb Vasc Biol J Ferrieres, CF Sing, M Roy, J Davignon and S... more ... 1994;14;1553-1560 Arterioscler Thromb Vasc Biol J Ferrieres, CF Sing, M Roy, J Davignon and S Lussier-Cacan hypercholesterolemia. ... Sex-Specific Effects Jean Ferrieres, Charles F. Sing, Madeleine Roy, Jean Davignon, Suzanne Lussier-Cacan ...
A major reduction in ischemic cardiovascular diseases depends on prevention of risk factors (RF) ... more A major reduction in ischemic cardiovascular diseases depends on prevention of risk factors (RF) for atherosclerosis. To assess how screening and treatment of these RF were undertaken in an outpatient setting, we reviewed 300 charts of Swiss men (age 17 to 86, mean 50) who were compliant with medical follow-up. We noticed that the six RF taken into account were insufficiently investigated among young people. Furthermore, hypercholesterolemia was largely underinvestigated, even in the presence of other RF for atherosclerosis. These findings indicate that both the importance of early detection and the clinical significance of dyslipidemia are underestimated by physicians. This situation would be improved by a health policy adapted to Swiss medical practice which defined rules of screening and treatment of RF for atherosclerosis.
In medical practice, the consultation of specific information often proves necessary, but not all... more In medical practice, the consultation of specific information often proves necessary, but not all practitioners have access to a library rich enough in periodicals and up-to-date articles. However, since the rise of combined telecommunication and computer technology, it is possible to correct this deficiency by access to medical and scientific data bases using a personal computer and an easily learned technique. The object of this article is to present the steps necessary for such an acquisition.
The prevalence and clinical aspects of high-HDL-cholesterolemia were investigated in 2000 patient... more The prevalence and clinical aspects of high-HDL-cholesterolemia were investigated in 2000 patients (1215 males and 785 females) aged 14-88 years in our medical outpatient department. The incidence of high-HDL-cholesterolemia was 7% (greater than 1.68 mmol/l) in males and 9.9% (greater than 1.94 mmol/l) in females and was associated in 80% of cases with a normal lipid profile according to the Fredrickson classification. Compared with patients with low-HDL-cholesterolemia, high-HDL-cholesterolemia distinguished by a lower incidence of obesity, of hyperlipidemia, of diabetes and of cigarette smoking. In contrast, daily alcohol intake was significantly higher. Fewer patients had a history of ischemic cardiovascular events. High-HDL-cholesterolemia appears to arise from both environmental and genetic factors.
International Journal of Epidemiology, 2013
PloS one, 2014
Cardiovascular diseases (CVD) mortality has been shown to follow a seasonal pattern. Several stud... more Cardiovascular diseases (CVD) mortality has been shown to follow a seasonal pattern. Several studies suggested several possible determinants of this pattern, including misclassification of causes of deaths. We aimed at assessing seasonality in overall, CVD, cancer and non-CVD/non-cancer mortality using data from 19 countries from different latitudes. Monthly mortality data were compiled from 19 countries, amounting to over 54 million deaths. We calculated ratios of the observed to the expected numbers of deaths in the absence of a seasonal pattern. Seasonal variation (peak to nadir difference) for overall and cause-specific (CVD, cancer or non-CVD/non-cancer) mortality was analyzed using the cosinor function model. Mortality from overall, CVD and non-CVD/non-cancer showed a consistent seasonal pattern. In both hemispheres, the number of deaths was higher than expected in winter. In countries close to the Equator the seasonal pattern was considerably lower for mortality from any caus...
... 1994;14;1553-1560 Arterioscler Thromb Vasc Biol J Ferrieres, CF Sing, M Roy, J Davignon and S... more ... 1994;14;1553-1560 Arterioscler Thromb Vasc Biol J Ferrieres, CF Sing, M Roy, J Davignon and S Lussier-Cacan hypercholesterolemia. ... Sex-Specific Effects Jean Ferrieres, Charles F. Sing, Madeleine Roy, Jean Davignon, Suzanne Lussier-Cacan ...
A major reduction in ischemic cardiovascular diseases depends on prevention of risk factors (RF) ... more A major reduction in ischemic cardiovascular diseases depends on prevention of risk factors (RF) for atherosclerosis. To assess how screening and treatment of these RF were undertaken in an outpatient setting, we reviewed 300 charts of Swiss men (age 17 to 86, mean 50) who were compliant with medical follow-up. We noticed that the six RF taken into account were insufficiently investigated among young people. Furthermore, hypercholesterolemia was largely underinvestigated, even in the presence of other RF for atherosclerosis. These findings indicate that both the importance of early detection and the clinical significance of dyslipidemia are underestimated by physicians. This situation would be improved by a health policy adapted to Swiss medical practice which defined rules of screening and treatment of RF for atherosclerosis.
In medical practice, the consultation of specific information often proves necessary, but not all... more In medical practice, the consultation of specific information often proves necessary, but not all practitioners have access to a library rich enough in periodicals and up-to-date articles. However, since the rise of combined telecommunication and computer technology, it is possible to correct this deficiency by access to medical and scientific data bases using a personal computer and an easily learned technique. The object of this article is to present the steps necessary for such an acquisition.
The prevalence and clinical aspects of high-HDL-cholesterolemia were investigated in 2000 patient... more The prevalence and clinical aspects of high-HDL-cholesterolemia were investigated in 2000 patients (1215 males and 785 females) aged 14-88 years in our medical outpatient department. The incidence of high-HDL-cholesterolemia was 7% (greater than 1.68 mmol/l) in males and 9.9% (greater than 1.94 mmol/l) in females and was associated in 80% of cases with a normal lipid profile according to the Fredrickson classification. Compared with patients with low-HDL-cholesterolemia, high-HDL-cholesterolemia distinguished by a lower incidence of obesity, of hyperlipidemia, of diabetes and of cigarette smoking. In contrast, daily alcohol intake was significantly higher. Fewer patients had a history of ischemic cardiovascular events. High-HDL-cholesterolemia appears to arise from both environmental and genetic factors.