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Papers by Francesco Bosco

Research paper thumbnail of Arthroscopic and endoscopic techniques for iliopsoas release in THA are safe and effective: a systematic review of the literature

European journal of orthopaedic surgery & traumatology, Jul 8, 2024

Research paper thumbnail of Challenges in Total Hip Arthroplasty with Prior Spinal Arthrodesis: A Comprehensive Review of Biomechanics, Complications, and Surgical Strategies

Journal of clinical medicine, May 28, 2024

Research paper thumbnail of Advancements in Anterior Cruciate Ligament Repair—Current State of the Art

Research paper thumbnail of The pie-crust surgical technique for medial collateral ligament release: enhancing visualization of the medial compartment in knee arthroscopy

Annals of joint, Apr 1, 2024

Research paper thumbnail of Nonmetallic tension band fixation is a viable and low-complication surgical technique in patellar fractures: a five-year retrospective study

European journal of orthopaedic surgery & traumatology, Mar 26, 2024

Research paper thumbnail of No significant clinical differences between native or reduced posterior tibial slope in kinematically aligned total knee replacement with posterior cruciate-retaining

Journal of Orthopaedics, Aug 1, 2024

Research paper thumbnail of Combining an Anterolateral Complex Procedure With Anterior Cruciate Ligament Reconstruction Reduces the Graft Reinjury Rate and Improves Clinical Outcomes: A Systematic Review and Meta-analysis of Randomized Controlled Trials

˜The œAmerican journal of sports medicine, Feb 14, 2024

Research paper thumbnail of Treatment of Scaphoid Non-Unions with Custom-Made 3D-Printed Titanium Partial and Total Scaphoid Prostheses and Scaphoid Interosseous Ligament Reconstruction

Research paper thumbnail of Irreducible knee dislocation: improved clinical outcomes of open and arthroscopic surgical treatment. A systematic review of the literature

European Journal of Orthopaedic Surgery and Traumatology, Nov 22, 2023

Research paper thumbnail of Outcomes of modular stem for the treatment of periprosthetic femoral fracture: a systematic review of the literature

Annals of joint, Sep 30, 2023

Research paper thumbnail of Superior outcomes of total hip arthroplasty without prior lumbar arthrodesis: a systematic review and meta-analysis

European Journal of Orthopaedic Surgery and Traumatology, Oct 16, 2023

Research paper thumbnail of Two-stage total joint replacement for hip or knee septic arthritis: post-traumatic etiology and difficult-to-treat infections predict poor outcomes

Archives of orthopaedic and trauma surgery, Mar 2, 2024

Research paper thumbnail of Long-Term Follow-Up of Medial Pivot Total Knee Arthroplasty: A Systematic Review of the Current Evidence

Prosthesis, Jul 12, 2023

This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY

Research paper thumbnail of Treatment of infected soft tissue loss

Plastic and Aesthetic Research

Hand coverage in infected soft tissue loss (STL) is a challenging clinical condition. Appropriate... more Hand coverage in infected soft tissue loss (STL) is a challenging clinical condition. Appropriate and well-timed antibiotic therapy and careful debridement are crucial for the success of the subsequent reconstructive procedure. Debridement must be radical, and all nonviable or infected tissue should be removed. Strict medical control and multiple procedures can be required when infection recurrence is observed after primary procedure. Secondary healing of STL is usually necessary in these complex conditions. Negative pressure wound therapy (NPWT) is often used as a temporary instrument to reduce oedema and drainage, facilitating the attainment of a clean wound for subsequent reconstruction. According to the type and size of the defect, multiple options ranging from skin grafts and substitutes to local and free flaps can be selected for the treatment of infected STL. A reconstructive ladder approach and case-by-case decision making should always be considered. Due to the unique funct...

Research paper thumbnail of Platelet-rich plasma for jumper's knee: a comprehensive review of efficacy, protocols, and future directions

European Journal of Orthopaedic Surgery & Traumatology

Purpose This comprehensive review evaluates the current state of platelet-rich plasma (PRP) treat... more Purpose This comprehensive review evaluates the current state of platelet-rich plasma (PRP) treatment for jumper's knee, also known as patellar tendinopathy. The aim is to assess the efficacy of PRP as a therapeutic option compared to other available procedures, investigate the benefits and potential drawbacks of PRP infiltration, and provide insights into the optimal protocols for PRP preparation and administration. Methods A comprehensive literature search of English articles published up to June 2023 was conducted using PubMed and Scopus databases. Studies evaluating PRP for treating jumper's knee or patellar tendinopathy were analyzed to assess the current state of research in this field. Results PRP has demonstrated promising results in promoting cellular remodeling and accelerating the healing process in the jumper's knee. It shows potential benefits in pain reduction, improved function, and accelerated recovery. However, the efficacy of PRP varies depending on pat...

Research paper thumbnail of Indications, complications, and clinical outcomes of fixation and acute total hip arthroplasty for the treatment of acetabular fractures: A systematic review

European Journal of Orthopaedic Surgery & Traumatology

Purpose Acetabular fracture fixation can be challenging, especially in the elderly. Open reductio... more Purpose Acetabular fracture fixation can be challenging, especially in the elderly. Open reduction and internal fixation (ORIF) alone may not allow for early weight bearing and is associated with a high rate of secondary osteoarthritis; therefore, a combined hip procedure (CHP) or ORIF with acute total hip arthroplasty, may be beneficial in this population. The objective of this study was to perform a systematic review of all reported cases of CHP. Methods PubMed, Embase, Scopus, and Cochrane databases were searched for studies analyzing acetabular fractures in the elderly managed with a combined hip procedure (CHP). The research was performed following the PRISMA guidelines. The included studies' methodological quality was evaluated using the MINORS score. The present study was registered on PROSPERO. Results Eleven clinical studies were included in the final analysis. The mean age was 74.4 (63.2–78) years. Low-energy trauma was the most common mechanism of injury (64%). The mo...

Research paper thumbnail of Is Gentamicin Elution Influenced by the Timing of Antibiotic Addition to the Bone Cement? An In Vitro Study on Articulating Hip Spacers

Prosthesis

Periprosthetic Joint Infection (PJI) is a challenging complication after joint replacements, and ... more Periprosthetic Joint Infection (PJI) is a challenging complication after joint replacements, and cement spacers are standard treatment in two-stage revision surgery. This experimental in vitro study aimed to evaluate the elution properties of different gentamicin formulations from commercially available intraoperative molded hip cement spacers. The study compared spacers prepared with premixed antibiotic bone cement, spacers with antibiotic powder added during preparation, spacers stored for two months, and spacers with an additional antibiotic. The results showed that the timing of antibiotic addition influenced gentamicin elution, with immediate elution resulting in higher levels than stored spacers. Spacers with antibiotic powder added during preparation exhibited higher elution than premixed antibiotic spacers. Furthermore, adding vancomycin to the bone cement significantly increased gentamicin elution. These findings suggest that optimizing the timing and method of antibiotic a...

Research paper thumbnail of Surgical treatment of popliteomeniscal fascicles tears is associated with better patient-reported outcome measures. A systematic review and meta-analysis

European Journal of Orthopaedic Surgery & Traumatology

Purpose Popliteomeniscal fascicles (PMFs) are a component of the popliteal hiatus complex in the ... more Purpose Popliteomeniscal fascicles (PMFs) are a component of the popliteal hiatus complex in the knee, and their injury primarily affects young athletes participating in sports activities involving twisting movements. The identification of PMFs tears presents a challenge, often accompanied by lateral pain and a locking sensation. The objective of this systematic review (SR) and meta-analysis is to enhance the suspicion and recognition of PMFs tears, aiming to facilitate the treatment of this condition, particularly in symptomatic young patients. Methods A comprehensive search, focused on studies examining PMFs injuries and their treatment, was conducted in four databases, PubMed, Scopus, Embase, and Web of Science. The ROBINS-I tool was used to evaluate the risks of bias. The PRISMA flow diagram was used to conduct the research and select the included studies. A meta-analysis was conducted for the Lysholm score, the Tegner Activity Scale, and the subjective IKDC score. The present S...

Research paper thumbnail of Two-stage revision in periprosthetic joint infection of the hip using a new intraoperatively molded articulating spacer design

Journal of Clinical Orthopaedics and Trauma

Research paper thumbnail of Comparison between gaits after a medial pivot and posterior stabilized primary total knee arthroplasty: a systematic review of the literature

Arthroplasty

Background Total knee arthroplasty (TKA) is one of the most performed orthopedic procedures world... more Background Total knee arthroplasty (TKA) is one of the most performed orthopedic procedures worldwide. While excellent efficacy has been reported, about 20% of patients are not satisfied with the result. A potential cause is the problematic reproduction of knee kinematics. This systematic review examines gait analysis studies in primary medial pivot (MP) and posterior stabilized (PS) TKAs to investigate the differences between the two prosthesis designs. Methods A systematic review was conducted by following PRISMA guidelines. Five databases (PubMed, Medline, Embase, Scopus and the Cochrane Database of Systematic Reviews) were analyzed, and eligible articles were evaluated in terms of the levels of evidence. The methodological quality of the articles was assessed by using the MINORS scoring. This review was registered in PROSPERO. Results Nine studies were included. Gait analysis was performed in 197 MP TKA and 192 PS TKA patients. PS TKA cases showed (P < 0.05) a significantly h...

Research paper thumbnail of Arthroscopic and endoscopic techniques for iliopsoas release in THA are safe and effective: a systematic review of the literature

European journal of orthopaedic surgery & traumatology, Jul 8, 2024

Research paper thumbnail of Challenges in Total Hip Arthroplasty with Prior Spinal Arthrodesis: A Comprehensive Review of Biomechanics, Complications, and Surgical Strategies

Journal of clinical medicine, May 28, 2024

Research paper thumbnail of Advancements in Anterior Cruciate Ligament Repair—Current State of the Art

Research paper thumbnail of The pie-crust surgical technique for medial collateral ligament release: enhancing visualization of the medial compartment in knee arthroscopy

Annals of joint, Apr 1, 2024

Research paper thumbnail of Nonmetallic tension band fixation is a viable and low-complication surgical technique in patellar fractures: a five-year retrospective study

European journal of orthopaedic surgery & traumatology, Mar 26, 2024

Research paper thumbnail of No significant clinical differences between native or reduced posterior tibial slope in kinematically aligned total knee replacement with posterior cruciate-retaining

Journal of Orthopaedics, Aug 1, 2024

Research paper thumbnail of Combining an Anterolateral Complex Procedure With Anterior Cruciate Ligament Reconstruction Reduces the Graft Reinjury Rate and Improves Clinical Outcomes: A Systematic Review and Meta-analysis of Randomized Controlled Trials

˜The œAmerican journal of sports medicine, Feb 14, 2024

Research paper thumbnail of Treatment of Scaphoid Non-Unions with Custom-Made 3D-Printed Titanium Partial and Total Scaphoid Prostheses and Scaphoid Interosseous Ligament Reconstruction

Research paper thumbnail of Irreducible knee dislocation: improved clinical outcomes of open and arthroscopic surgical treatment. A systematic review of the literature

European Journal of Orthopaedic Surgery and Traumatology, Nov 22, 2023

Research paper thumbnail of Outcomes of modular stem for the treatment of periprosthetic femoral fracture: a systematic review of the literature

Annals of joint, Sep 30, 2023

Research paper thumbnail of Superior outcomes of total hip arthroplasty without prior lumbar arthrodesis: a systematic review and meta-analysis

European Journal of Orthopaedic Surgery and Traumatology, Oct 16, 2023

Research paper thumbnail of Two-stage total joint replacement for hip or knee septic arthritis: post-traumatic etiology and difficult-to-treat infections predict poor outcomes

Archives of orthopaedic and trauma surgery, Mar 2, 2024

Research paper thumbnail of Long-Term Follow-Up of Medial Pivot Total Knee Arthroplasty: A Systematic Review of the Current Evidence

Prosthesis, Jul 12, 2023

This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY

Research paper thumbnail of Treatment of infected soft tissue loss

Plastic and Aesthetic Research

Hand coverage in infected soft tissue loss (STL) is a challenging clinical condition. Appropriate... more Hand coverage in infected soft tissue loss (STL) is a challenging clinical condition. Appropriate and well-timed antibiotic therapy and careful debridement are crucial for the success of the subsequent reconstructive procedure. Debridement must be radical, and all nonviable or infected tissue should be removed. Strict medical control and multiple procedures can be required when infection recurrence is observed after primary procedure. Secondary healing of STL is usually necessary in these complex conditions. Negative pressure wound therapy (NPWT) is often used as a temporary instrument to reduce oedema and drainage, facilitating the attainment of a clean wound for subsequent reconstruction. According to the type and size of the defect, multiple options ranging from skin grafts and substitutes to local and free flaps can be selected for the treatment of infected STL. A reconstructive ladder approach and case-by-case decision making should always be considered. Due to the unique funct...

Research paper thumbnail of Platelet-rich plasma for jumper's knee: a comprehensive review of efficacy, protocols, and future directions

European Journal of Orthopaedic Surgery & Traumatology

Purpose This comprehensive review evaluates the current state of platelet-rich plasma (PRP) treat... more Purpose This comprehensive review evaluates the current state of platelet-rich plasma (PRP) treatment for jumper's knee, also known as patellar tendinopathy. The aim is to assess the efficacy of PRP as a therapeutic option compared to other available procedures, investigate the benefits and potential drawbacks of PRP infiltration, and provide insights into the optimal protocols for PRP preparation and administration. Methods A comprehensive literature search of English articles published up to June 2023 was conducted using PubMed and Scopus databases. Studies evaluating PRP for treating jumper's knee or patellar tendinopathy were analyzed to assess the current state of research in this field. Results PRP has demonstrated promising results in promoting cellular remodeling and accelerating the healing process in the jumper's knee. It shows potential benefits in pain reduction, improved function, and accelerated recovery. However, the efficacy of PRP varies depending on pat...

Research paper thumbnail of Indications, complications, and clinical outcomes of fixation and acute total hip arthroplasty for the treatment of acetabular fractures: A systematic review

European Journal of Orthopaedic Surgery & Traumatology

Purpose Acetabular fracture fixation can be challenging, especially in the elderly. Open reductio... more Purpose Acetabular fracture fixation can be challenging, especially in the elderly. Open reduction and internal fixation (ORIF) alone may not allow for early weight bearing and is associated with a high rate of secondary osteoarthritis; therefore, a combined hip procedure (CHP) or ORIF with acute total hip arthroplasty, may be beneficial in this population. The objective of this study was to perform a systematic review of all reported cases of CHP. Methods PubMed, Embase, Scopus, and Cochrane databases were searched for studies analyzing acetabular fractures in the elderly managed with a combined hip procedure (CHP). The research was performed following the PRISMA guidelines. The included studies' methodological quality was evaluated using the MINORS score. The present study was registered on PROSPERO. Results Eleven clinical studies were included in the final analysis. The mean age was 74.4 (63.2–78) years. Low-energy trauma was the most common mechanism of injury (64%). The mo...

Research paper thumbnail of Is Gentamicin Elution Influenced by the Timing of Antibiotic Addition to the Bone Cement? An In Vitro Study on Articulating Hip Spacers

Prosthesis

Periprosthetic Joint Infection (PJI) is a challenging complication after joint replacements, and ... more Periprosthetic Joint Infection (PJI) is a challenging complication after joint replacements, and cement spacers are standard treatment in two-stage revision surgery. This experimental in vitro study aimed to evaluate the elution properties of different gentamicin formulations from commercially available intraoperative molded hip cement spacers. The study compared spacers prepared with premixed antibiotic bone cement, spacers with antibiotic powder added during preparation, spacers stored for two months, and spacers with an additional antibiotic. The results showed that the timing of antibiotic addition influenced gentamicin elution, with immediate elution resulting in higher levels than stored spacers. Spacers with antibiotic powder added during preparation exhibited higher elution than premixed antibiotic spacers. Furthermore, adding vancomycin to the bone cement significantly increased gentamicin elution. These findings suggest that optimizing the timing and method of antibiotic a...

Research paper thumbnail of Surgical treatment of popliteomeniscal fascicles tears is associated with better patient-reported outcome measures. A systematic review and meta-analysis

European Journal of Orthopaedic Surgery & Traumatology

Purpose Popliteomeniscal fascicles (PMFs) are a component of the popliteal hiatus complex in the ... more Purpose Popliteomeniscal fascicles (PMFs) are a component of the popliteal hiatus complex in the knee, and their injury primarily affects young athletes participating in sports activities involving twisting movements. The identification of PMFs tears presents a challenge, often accompanied by lateral pain and a locking sensation. The objective of this systematic review (SR) and meta-analysis is to enhance the suspicion and recognition of PMFs tears, aiming to facilitate the treatment of this condition, particularly in symptomatic young patients. Methods A comprehensive search, focused on studies examining PMFs injuries and their treatment, was conducted in four databases, PubMed, Scopus, Embase, and Web of Science. The ROBINS-I tool was used to evaluate the risks of bias. The PRISMA flow diagram was used to conduct the research and select the included studies. A meta-analysis was conducted for the Lysholm score, the Tegner Activity Scale, and the subjective IKDC score. The present S...

Research paper thumbnail of Two-stage revision in periprosthetic joint infection of the hip using a new intraoperatively molded articulating spacer design

Journal of Clinical Orthopaedics and Trauma

Research paper thumbnail of Comparison between gaits after a medial pivot and posterior stabilized primary total knee arthroplasty: a systematic review of the literature

Arthroplasty

Background Total knee arthroplasty (TKA) is one of the most performed orthopedic procedures world... more Background Total knee arthroplasty (TKA) is one of the most performed orthopedic procedures worldwide. While excellent efficacy has been reported, about 20% of patients are not satisfied with the result. A potential cause is the problematic reproduction of knee kinematics. This systematic review examines gait analysis studies in primary medial pivot (MP) and posterior stabilized (PS) TKAs to investigate the differences between the two prosthesis designs. Methods A systematic review was conducted by following PRISMA guidelines. Five databases (PubMed, Medline, Embase, Scopus and the Cochrane Database of Systematic Reviews) were analyzed, and eligible articles were evaluated in terms of the levels of evidence. The methodological quality of the articles was assessed by using the MINORS scoring. This review was registered in PROSPERO. Results Nine studies were included. Gait analysis was performed in 197 MP TKA and 192 PS TKA patients. PS TKA cases showed (P < 0.05) a significantly h...