Ali Bouzekri | University of 20 Aoùt 1955-Skikda (original) (raw)

Papers by Ali Bouzekri

CYTOLOGIA

Spirotetramat (SPT) is a new insecticide derivative of tetronic acid used extensively in agricult... more Spirotetramat (SPT) is a new insecticide derivative of tetronic acid used extensively in agriculture to enhance the protection of major food crops against scales and aphids. This study aims to determine SPT s cytotoxic and genotoxic effects using two model plants, Allium cepa and Vicia faba. This evaluation consists of studying the root growth, morphology, and color and the parameters of mitotic index (MI) and chromosome aberrations (CAs) as accurate toxicity markers. Our results showed a significant decrease in mean root length in A. cepa from the 0.0025% concentration. In contrast, a substantial reduction in mean root length in V. faba was recorded only at the 0.02% concentration. Furthermore, the MI was decreased proportionally with increasing concentration and time of exposure to SPT. A significant increase in CAs was observed in A. cepa and V. faba from the 0.0025% concentration after 24 h of treatment. The substantial reduction in MI and abundance of CAs indicated strong genotoxicity of SPT. From the data obtained, it can be concluded that SPT could be absorbed by the exposed plant or other non-target organisms in the proximity, causing damage to agricultural plants, affecting their genomes, and harming the environment.

Caryologia

Tribulus terrestris is a plant of the Zygophyllaceae family frequently used worldwide to treat va... more Tribulus terrestris is a plant of the Zygophyllaceae family frequently used worldwide to treat various diseases due to the therapeutic effects of its pharmacological components. This study examines the cytotoxic and genotoxic effects of T. terrestris using two plant models, Allium cepa and Vicia faba. Extracts of 0.00625, 0.0125, 0.025, 0.05 and 0.1mg/mL were tested on meristematic cells of A. cepa and V. faba roots. This assessment includes the study of root growth, structure and coloration, as well as the determination of the mitotic index (MI) and chromosomal aberrations (CAs) as accurate indicators of toxicity. Our results showed a significant decrease in the mean length of roots treated with 0.025, 0.05 and 0.1 mg/ml for A. cepa and 0.1 mg/ml for V. faba. Cytotoxicity and genotoxicity results showed a significant decrease in MI from 0.025 mg/ml in A. cepa and from 0.05 mg/ml in V. faba, and this decrease in MI is linked to the increase in concentration and treatment time with T...

Synergies Roumanie, 2017

Les relations entre la Roumanie et la France sont très anciennes, la reconstruction de l'Euro... more Les relations entre la Roumanie et la France sont très anciennes, la reconstruction de l'Europe unie avec la communauté du charbon et de l'acier (CECA) et l'élargissement de l'union à 28 pays a rendu la Roumanie à son espace géostratégique naturel. Dans cet article, nous abordons la question de l'annexion de la Roumanie à l'Union européenne au-delà des efforts de l'état français afin de favoriser son intégration à l'Union européenne et à l'OTAN.

Pakistan Journal of Zoology, 2022

Tribulus terrestris is traditionally used to treat various diseases. The current research aimed t... more Tribulus terrestris is traditionally used to treat various diseases. The current research aimed to study the protective effects of methanolic extract of Tribulus terrestris (TT) against Spirotetramat (SPT) induced reproductive toxicity in adult male domestic pigeons (Columba livia domestica). For ten consecutive weeks and under an artificial photoperiod (19L: 5D), thirty male pigeons weighing approximately 309,20 ± 14,41g were divided equally into six groups as follows: CT served as the control, SPT group orally given with 15 mg/kg BW/day, TT100 and TT50 groups orally administrated with 100 and 50 mg/kg BW/
day of TT respectively, and SPT+ TT100 and SPT + TT50 groups. Testicular volume and body weight were measured each two weeks. Whereas histopathological profile and luteinizing hormone (LH), folliclestimulating hormone (FSH), testosterone (T), total cholesterol (TC), LDL-C, HDL-C, and triglyceride (TG) were evaluated at week 10. The obtained data reveal that under a long photoperiod of 19L:5D, sexual activity lasted only 06 weeks in the control and TT groups, with a significant increase in testicular volume followed by spontaneous gonadal regression up to week 10. But testicular weights were superior in TT pigeons compared to the control during all experiments. However, the administration of SPT has suppressed gonadal growth and delayed photo-refractoriness. Sex hormones levels revealed a significant increase in LH and FSH levels in all groups compared to controls. However, a significant depletion in testosterone levels. Nevertheless, there was a substantial increase in TC, HDL-C, and LDL-C levels.
Furthermore, co-administration of TT with SPT restored the lowered testicular volume, relative testicular weight, and T level but decreased the TC, HDL-C, and LDL-C levels. Finally, the histopathological investigation revealed degenerative changes in testes and gonad damage in the SPT group. However, TT reduced the damage induced by SPT. In conclusion, TT could be beneficial in preventing SPT reproductive

arXiv: Analysis of PDEs, 2019

The Foldy-Lax (or the point-interaction) approximation of the electromagnetic fields generated by... more The Foldy-Lax (or the point-interaction) approximation of the electromagnetic fields generated by a cluster of small scaled inhomogeneities is derived in the mesoscale regime, i.e. when the minimum distance delta\deltadelta between the particles is proportional to their maximum radi aaa in the form delta=cr;a\delta=c_r \; adelta=cr;a with a positive constant crc_rcr that we call the dilution parameter. We consider two types of families of inhomogeneities. In the first one, the small particles are modeled by anisotropic electric permittivities and/or magnetic permeabilities with possibly complex values. In the second one, they are given as perfectly conductive inclusions. In both the cases, we provide the dominating field (the so-called Foldy-Lax field) with explicit error estimates in terms of the dilution parameter crc_rcr. In the case of perfectly conductive inclusions, the results provided here improve sharply the ones derived recently in \cite{AB-SM:MMS2019}. Such approximations are key steps in different re...

Annales Henri Poincaré, 2021

The point-interaction approximation (or the Foldy-Lax approximation) of the electromagnetic field... more The point-interaction approximation (or the Foldy-Lax approximation) of the electromagnetic fields generated by a cluster of small scaled inhomogeneities is derived in the mesoscale (i.e. mesoscopic scale) regime, that is when the minimum distance δ between the particles is proportional to their maximum diameter a in the form δ = cr a with a positive constant cr that we call the dilution parameter. The small particles are modeled by anisotropic and variable electric permittivities and/or magnetic permeabilities with possibly complex values. We provide the dominating field (the so-called Foldy-Lax field) with explicit error estimates in terms of the dilution parameter cr uniformly in terms of the distribution of these inhomogeneities. Such approximations are key steps in different research areas as imaging and material sciences.

Multiscale Modeling & Simulation, 2019

We deal with the electromagnetic waves propagation in the harmonic regime. We derive the Foldy-La... more We deal with the electromagnetic waves propagation in the harmonic regime. We derive the Foldy-Lax approximation of the scattered fields generated by a cluster of small conductive inhomogeneities arbitrarily distributed in a bounded domain Ω of R 3. This approximation is valid under a sufficient but general condition on the number of such inhomogeneities m, their maximum radii ǫ and the minimum distances between them δ, of the form (ln m) 1 3 ǫ δ ≤ C, where C is a constant depending only on the Lipschitz characters of the scaled inhomogeneities. In addition, we provide explicit error estimates of this approximation in terms of aforementioned parameters, m, ǫ, δ but also the used frequencies k under the Rayleigh regime. Both the far-fields and the near-fields (stated at a distance δ to the cluster) are estimated. In particular, for a moderate number of small inhomogeneities m, the derived expansions are valid in the mesoscale regime where δ ∼ ǫ. At the mathematical analysis level and based on integral equation methods, we prove a priori estimates of the densities in the L 2,Div t spaces instead of the usual L 2 spaces (which are not enough). A key point in such a proof is a derivation of a particular Helmholtz type decomposition of the densities. Those estimates allow to obtain the needed qualitative as well as quantitative estimates while refining the approximation. Finally, to prove the invertibility of the Foldy-Lax linear algebraic system, we reduce the coercivity inequality to the one related to the scalar Helmholtz model. As this linear algebraic system comes from the boundary conditions, such a reduction is not straightforward.

CYTOLOGIA

Spirotetramat (SPT) is a new insecticide derivative of tetronic acid used extensively in agricult... more Spirotetramat (SPT) is a new insecticide derivative of tetronic acid used extensively in agriculture to enhance the protection of major food crops against scales and aphids. This study aims to determine SPT s cytotoxic and genotoxic effects using two model plants, Allium cepa and Vicia faba. This evaluation consists of studying the root growth, morphology, and color and the parameters of mitotic index (MI) and chromosome aberrations (CAs) as accurate toxicity markers. Our results showed a significant decrease in mean root length in A. cepa from the 0.0025% concentration. In contrast, a substantial reduction in mean root length in V. faba was recorded only at the 0.02% concentration. Furthermore, the MI was decreased proportionally with increasing concentration and time of exposure to SPT. A significant increase in CAs was observed in A. cepa and V. faba from the 0.0025% concentration after 24 h of treatment. The substantial reduction in MI and abundance of CAs indicated strong genotoxicity of SPT. From the data obtained, it can be concluded that SPT could be absorbed by the exposed plant or other non-target organisms in the proximity, causing damage to agricultural plants, affecting their genomes, and harming the environment.

Caryologia

Tribulus terrestris is a plant of the Zygophyllaceae family frequently used worldwide to treat va... more Tribulus terrestris is a plant of the Zygophyllaceae family frequently used worldwide to treat various diseases due to the therapeutic effects of its pharmacological components. This study examines the cytotoxic and genotoxic effects of T. terrestris using two plant models, Allium cepa and Vicia faba. Extracts of 0.00625, 0.0125, 0.025, 0.05 and 0.1mg/mL were tested on meristematic cells of A. cepa and V. faba roots. This assessment includes the study of root growth, structure and coloration, as well as the determination of the mitotic index (MI) and chromosomal aberrations (CAs) as accurate indicators of toxicity. Our results showed a significant decrease in the mean length of roots treated with 0.025, 0.05 and 0.1 mg/ml for A. cepa and 0.1 mg/ml for V. faba. Cytotoxicity and genotoxicity results showed a significant decrease in MI from 0.025 mg/ml in A. cepa and from 0.05 mg/ml in V. faba, and this decrease in MI is linked to the increase in concentration and treatment time with T...

Synergies Roumanie, 2017

Les relations entre la Roumanie et la France sont très anciennes, la reconstruction de l'Euro... more Les relations entre la Roumanie et la France sont très anciennes, la reconstruction de l'Europe unie avec la communauté du charbon et de l'acier (CECA) et l'élargissement de l'union à 28 pays a rendu la Roumanie à son espace géostratégique naturel. Dans cet article, nous abordons la question de l'annexion de la Roumanie à l'Union européenne au-delà des efforts de l'état français afin de favoriser son intégration à l'Union européenne et à l'OTAN.

Pakistan Journal of Zoology, 2022

Tribulus terrestris is traditionally used to treat various diseases. The current research aimed t... more Tribulus terrestris is traditionally used to treat various diseases. The current research aimed to study the protective effects of methanolic extract of Tribulus terrestris (TT) against Spirotetramat (SPT) induced reproductive toxicity in adult male domestic pigeons (Columba livia domestica). For ten consecutive weeks and under an artificial photoperiod (19L: 5D), thirty male pigeons weighing approximately 309,20 ± 14,41g were divided equally into six groups as follows: CT served as the control, SPT group orally given with 15 mg/kg BW/day, TT100 and TT50 groups orally administrated with 100 and 50 mg/kg BW/
day of TT respectively, and SPT+ TT100 and SPT + TT50 groups. Testicular volume and body weight were measured each two weeks. Whereas histopathological profile and luteinizing hormone (LH), folliclestimulating hormone (FSH), testosterone (T), total cholesterol (TC), LDL-C, HDL-C, and triglyceride (TG) were evaluated at week 10. The obtained data reveal that under a long photoperiod of 19L:5D, sexual activity lasted only 06 weeks in the control and TT groups, with a significant increase in testicular volume followed by spontaneous gonadal regression up to week 10. But testicular weights were superior in TT pigeons compared to the control during all experiments. However, the administration of SPT has suppressed gonadal growth and delayed photo-refractoriness. Sex hormones levels revealed a significant increase in LH and FSH levels in all groups compared to controls. However, a significant depletion in testosterone levels. Nevertheless, there was a substantial increase in TC, HDL-C, and LDL-C levels.
Furthermore, co-administration of TT with SPT restored the lowered testicular volume, relative testicular weight, and T level but decreased the TC, HDL-C, and LDL-C levels. Finally, the histopathological investigation revealed degenerative changes in testes and gonad damage in the SPT group. However, TT reduced the damage induced by SPT. In conclusion, TT could be beneficial in preventing SPT reproductive

arXiv: Analysis of PDEs, 2019

The Foldy-Lax (or the point-interaction) approximation of the electromagnetic fields generated by... more The Foldy-Lax (or the point-interaction) approximation of the electromagnetic fields generated by a cluster of small scaled inhomogeneities is derived in the mesoscale regime, i.e. when the minimum distance delta\deltadelta between the particles is proportional to their maximum radi aaa in the form delta=cr;a\delta=c_r \; adelta=cr;a with a positive constant crc_rcr that we call the dilution parameter. We consider two types of families of inhomogeneities. In the first one, the small particles are modeled by anisotropic electric permittivities and/or magnetic permeabilities with possibly complex values. In the second one, they are given as perfectly conductive inclusions. In both the cases, we provide the dominating field (the so-called Foldy-Lax field) with explicit error estimates in terms of the dilution parameter crc_rcr. In the case of perfectly conductive inclusions, the results provided here improve sharply the ones derived recently in \cite{AB-SM:MMS2019}. Such approximations are key steps in different re...

Annales Henri Poincaré, 2021

The point-interaction approximation (or the Foldy-Lax approximation) of the electromagnetic field... more The point-interaction approximation (or the Foldy-Lax approximation) of the electromagnetic fields generated by a cluster of small scaled inhomogeneities is derived in the mesoscale (i.e. mesoscopic scale) regime, that is when the minimum distance δ between the particles is proportional to their maximum diameter a in the form δ = cr a with a positive constant cr that we call the dilution parameter. The small particles are modeled by anisotropic and variable electric permittivities and/or magnetic permeabilities with possibly complex values. We provide the dominating field (the so-called Foldy-Lax field) with explicit error estimates in terms of the dilution parameter cr uniformly in terms of the distribution of these inhomogeneities. Such approximations are key steps in different research areas as imaging and material sciences.

Multiscale Modeling & Simulation, 2019

We deal with the electromagnetic waves propagation in the harmonic regime. We derive the Foldy-La... more We deal with the electromagnetic waves propagation in the harmonic regime. We derive the Foldy-Lax approximation of the scattered fields generated by a cluster of small conductive inhomogeneities arbitrarily distributed in a bounded domain Ω of R 3. This approximation is valid under a sufficient but general condition on the number of such inhomogeneities m, their maximum radii ǫ and the minimum distances between them δ, of the form (ln m) 1 3 ǫ δ ≤ C, where C is a constant depending only on the Lipschitz characters of the scaled inhomogeneities. In addition, we provide explicit error estimates of this approximation in terms of aforementioned parameters, m, ǫ, δ but also the used frequencies k under the Rayleigh regime. Both the far-fields and the near-fields (stated at a distance δ to the cluster) are estimated. In particular, for a moderate number of small inhomogeneities m, the derived expansions are valid in the mesoscale regime where δ ∼ ǫ. At the mathematical analysis level and based on integral equation methods, we prove a priori estimates of the densities in the L 2,Div t spaces instead of the usual L 2 spaces (which are not enough). A key point in such a proof is a derivation of a particular Helmholtz type decomposition of the densities. Those estimates allow to obtain the needed qualitative as well as quantitative estimates while refining the approximation. Finally, to prove the invertibility of the Foldy-Lax linear algebraic system, we reduce the coercivity inequality to the one related to the scalar Helmholtz model. As this linear algebraic system comes from the boundary conditions, such a reduction is not straightforward.