Yahya Bachra | University of Hassan II Casablanca (original) (raw)

Papers by Yahya Bachra

Polymer Bulletin, Nov 21, 2023

Properties and Applications of Superabsorbent Polymers, 2023

Journal of Drug Delivery Science and Technology

CRC Press eBooks, Nov 21, 2022

Nanotechnology in Intelligent Food Packaging

Chitin and Chitosan - Physicochemical Properties and Industrial Applications [Working Title], 2020

Recently, chitosan (CS) was given much attention as a functional biopolymer for designing various... more Recently, chitosan (CS) was given much attention as a functional biopolymer for designing various hydrogels for industrial, environmental and biomedical applications, but their biomedical use is limited due to the toxicity of the crosslinker agents. To overcome this inconvenience, we developed an auto cross-linked material based on a chitosan backbone that carries an amino and aldehyde moieties. This new drug delivery system (DDS) was designed by using oxidized chitosan (OCS) that crosslinks chitosan (CS). In the first part, a simple, rapid, low-cost and eco-friendly green method was introduced to synthesize magnetite nanoparticles (Fe3O4-NPs) successfully. These nanoparticles Fe3O4 have received a great deal of attention in the biomedical field. Especially in a targeted drug delivery system, drug-loaded Fe3O4-NPs can accumulate at the tumor site by the aid of an external magnetic field and increase the effectiveness of drug release to the tumor site. In the second part, we have inc...

Journal of Chemistry, 2020

In this study, chitosan-based hydrogels were produced by incorporating three drugs with a differe... more In this study, chitosan-based hydrogels were produced by incorporating three drugs with a different solubility into a polymer matrix. The lyophilized chitosan salt was prepared using an innovative and less-expensive synthetic process by the freeze-drying technique. Firstly, the three drugs (caffeine, ascorbic acid, and 5-fluorouracil (5-FU)) were selected as model drugs to test the in vitro release behavior of the hydrogel. The drugs were solubilized in chitosan salt, lyophilized, and cross-linked with benzaldehyde involving the formation of a Schiff base with (–C=N-) linkage to produce a physical hydrogel. Subsequently, the physicochemical properties of N-benzyl chitosan and lyophilized chitosan salt were evaluated by Fourier-transform infrared (FTIR) spectra, scanning electron microscopy (SEM), and thermogravimetric analysis (TGA). The intrinsic viscosity of the conventional chitosan was determined by the Mark–Houwink–Sakurada equation. Moreover, the kinetics of hydrogel swelling ...

Chinese Journal of Analytical Chemistry

Superabsorbent polymers (SAPs) are materials that can absorb and retain large amounts of water an... more Superabsorbent polymers (SAPs) are materials that can absorb and retain large amounts of water and aqueous solutions. This has made them ideal for a variety of valuable applications in medicine, agriculture, and industry in general. Nevertheless, their use as a material for absorbing liquids in disposable baby diapers (DBD) remains the most usable. DBDs on the market today are made up of three main layers in addition to SAP. The topsheet, the closest to the skin, is designed to isolate the baby's skin from the wet inner core. The absorbent core (AC) which is a mixture of the SAP in a cellulose core called fluff pulp. The backsheet is a waterproof outer material made of polyethylene or polypropylene. Besides other materials that help contain urine and waste. However, the composition, quantity, and SAP distribution differ with the diaper brand, so a diaper absorption assessment is recommended to judge its quality. For that reason, nine representative samples of commercial brands o...

International Journal of Biomaterials

Nowadays, current global environmental problems include measures to eliminate or reduce the negat... more Nowadays, current global environmental problems include measures to eliminate or reduce the negative impact of chemicals from petroleum sources and, therefore, the use of materials from natural resources is increasingly recommended. In this context, natural-based superabsorbent polymers derived from polypeptides and polysaccharides have undergone chemical and biochemical modifications to improve their ability to absorb and retain large amounts of liquids. In the present paper, a new process has been used to overcome the side effects of radical polymerization in the manufacture of conventional polyacrylate superabsorbents (SAPs). Tragacanth gum (TG) was selected to prepare a new superabsorbent material (CMTG-GA) based on carboxymethyl tragacanth (CMTG) crosslinked with glutaraldehyde (GA). The characterization of the polymer was carried out by FTIR, TGA, XRD, and SEM. The effect of the amount of crosslinking agent and the pH on the water absorption capacity was also examined. Subsequ...