Giovanni Cobellis | Università Politecnica delle Marche, Italy (original) (raw)
Papers by Giovanni Cobellis
Prenatal Diagnosis, 1988
We report the ultrasound prenatal diagnosis a t the 30th week of macroglossia in two sibs with th... more We report the ultrasound prenatal diagnosis a t the 30th week of macroglossia in two sibs with the Wiedemann-Beckwith syndrome; the syndrome was also present in their mother. A study of high resolution chromosomes did not show any anomaly. KEY WORDS Macroglossia Wiedemann-Beckwith syndrome Ultrasound prenatal diagnosis EMG syndrome
International Journal of Medical Robotics and Computer Assisted Surgery, Jun 1, 2023
BackgroundRobot‐assisted approach to UVJ is getting more and more used in pediatric patients.Meth... more BackgroundRobot‐assisted approach to UVJ is getting more and more used in pediatric patients.MethodsIn this retrospective study 26 patients affected by nephro‐urological malformations, robotic‐surgically treated from 2016 and 2021 at 3 Pediatric Surgery Department were included: 3 (11.5%) primary obstructive megaureter, 2 (7.7%) dysplastic kidneys, 3 (11.5%) duplex collecting system, 18 (69.2%) primary vescico‐ureteral reflux (VUR).ResultsMean age at surgery was 6 years old. 22 (84.6%) underwent Lich Gregoire extravesical ureteral reimplantation, 4 (15.4%) total nephroureterectomy. Mean operative time was 230 min. No conversions or intraoperative complications. Median hospital stay was 4 days. There were 4 (15.38%) postoperative complications: 3 (11.54%) persistent VUR and 1 (3.84%) refluxing megaureter. 2 (7.7%) redo‐surgery.ConclusionsRobotic Surgery should be considered a safe and effective technique for treatment of UVJ anomalies in children, because it firstly allows surgeons to approach both upper and lower ureteral ends without modifying trocars’ placement.
Journal of pediatric surgery case reports, 2021
Abstract Echinococcosis is a parasitic zoonosis in which humans are involved as an intermediate h... more Abstract Echinococcosis is a parasitic zoonosis in which humans are involved as an intermediate host. It is a very common pathology in the areas of Eastern Europe and Asia, where the main activity is represented by pastoralism and animal breeding. In humans, the most frequently affected sites are the liver (60–70%) and lungs (20–30%), manifesting themselves with symptoms such as abdominal pain, coughing, dyspnea, hemoptysis, up to cases of anaphylactic shock. In Italy it is not a common disease with an incidence of 2:100.000 inhabitants, and it's extremely rare in pediatric population. In this work we presented a case of a 11-years male patient came for a persistent cough, to whom was found a giant cystic mass in the thorax. Serological tests confirmed the diagnosis of echinococcosis. Patient underwent to thoracotomy to remove the cyst and he begun the antiparasitic therapy. Post-operative outcome was good and the patient is, until now, free of problems. Echinococcosis is a challenging problem for a pediatric surgeon, especially in non-endemic area, not only because it is not a common disease in pediatric population, but also for the surgical management that can presents some difficulties and complications in the post-operative course.
PubMed, Aug 1, 2014
Aim: Aim of the study was to compare multichannel intraluminal impedance (MII)-pH monitoring vers... more Aim: Aim of the study was to compare multichannel intraluminal impedance (MII)-pH monitoring versus pH only, as first-line assessment of gastroesophageal reflux (GER) in children and to define the relation between GER and symptoms as well relation between types of GER and age of children. Methods: All the patients with GER were divided in three groups: A, younger than 24 months, B, older than 24 months with typical symptoms and C, older than 24 months with atypical symptoms. The groups A and C underwent a combined MII-pH recording. The group B underwent a only pH recording. MII-pH measurements were performed in 89 children (63 group A and 26 group C), only pH measurements in 170 cases (group B). Results: Sixty-seven of the 247 pH measurements demonstrated abnormal reflux indices: 25.0% (group A), 28.8% (group B) and 20.8% (group C). The number of the reflux periods and the total reflux index were highest in the patients of the group B, but the number of long reflux periods was highest in the group C. Abnormal values at MII results were found in 36 cases: 41.7% in group A (high number of weakly acid refluxes events) and 45.8% in group C (similar number of acid and weakly acid events). The MII were considered pathological because of high number of reflux episodes and symptom index ≥ 50% respectively in 60.0% and 40.0% of the group A and 27.3% and 62.7% of the group C. Conclusion: MII-pH study must be reserved to patients younger than 2-year old (high probability of weakly acid reflux) and children with atypical symptoms.
PubMed, Jul 1, 1995
Hemangioma of the bladder is a rare benign tumor. Hematuria is the most common symptom of the dis... more Hemangioma of the bladder is a rare benign tumor. Hematuria is the most common symptom of the disease. The Authors report their experience on two isolated cases of bladder hemangioma. The lesions were diagnosed by endoscopy and biopsy. In both cases the hemangiomas were electrocoagulated endoscopically. Follow-up examination after 1 year, has shown complete eradication of the lesion.
Digestive and Liver Disease, Oct 1, 2015
Gastroenterology Research and Practice, 2015
Transumbilical laparoscopic-assisted appendectomy (TULAA) is increasingly being performed worldwi... more Transumbilical laparoscopic-assisted appendectomy (TULAA) is increasingly being performed worldwide. The authors report their experience in the treatment of acute uncomplicated appendicitis in children with TULAA. From January 2008 to December 2012 all types of acute appendicitis were divided, according to the clinical and ultrasonographic findings, into complicated (appendiceal mass/abscess, diffuse peritonitis) and uncomplicated. Complicated appendicitis was treated by open appendectomy (OA). All patients with the suspicion of uncomplicated appendicitis were offered TULAA by all surgeons of the team. Conversion to open or laparoscopic appendectomy (LA) was performed in case of impossibility to complete TULAA, depending on the choice of surgeon. The histopathologic examination of appendix was always performed. 444 children (252 males) with acute appendicitis were treated. The mean age was 9.2 years (range, 2 to 14 years). Primary OA was performed in 144 cases. In 300 patients a transumbilical laparoscopic-assisted approach was performed. TULAA was completed in 252 patients. Conversion to OA was performed in 45 patients and to LA in 3. Conversion was related to the impossibility to adequately expose the appendix in 47 patients and bleeding in 1. The mean operative time for TULAA was 42 minutes. Histopathologic examination of the appendix removed by TULAA showed a phlegmonous/gangrenous type in 92.8% of cases. Among the 252 TULAA there were 11 cases of umbilical wound infection. TULAA is a feasible and effective procedure for uncomplicated appendicitis in children. It combines the advantages of open and laparoscopic technique (low operative time, low complications rate, and excellent cosmetic results).
Gynecological Endocrinology, May 9, 2022
Journal of pediatric surgery case reports, Jun 1, 2018
Gynecological Endocrinology, May 31, 2017
Objective: The authors present their experience in the management of pediatric patients with Herl... more Objective: The authors present their experience in the management of pediatric patients with Herlyn-Werner-Wunderlich syndrome (HWWS) considering clinical classification and anatomical characteristics of the malformation. Methods: All the data of the patient presented at our Pediatric Surgery Unit from February 2010 to August 2015 were collected. According to the type of malformations, patients were divided in 3 groups: A (completely obstructed hemivagina), B (incompletely obstructed hemivagina), and C (communication between the duplicated cervices). Results: Six patients were treated in the study period. The mean age was 9 years (2 months-15 years). According to the characteristics of the HWWS, we had 5 patients in group A, 1 in group B, and none in group C. One-stage surgical treatment was performed in all cases of complete obstruction, but in one case a second look was necessary for a better resection of the septum. At a mean follow-up of 18 months all patients were symptoms free. Conclusions: Prognosis of this malformation is good in case of early diagnosis and treatment. We suggest that when a renal agenesia is diagnosed, the patient needs an ultrasonographic follow-up of the contralateral kidney but also of the genital tract to find each minimal abnormalities, furthermore, a MRI scanning before the onset of menstruation can be necessary.
Digestive and Liver Disease, Oct 1, 2015
Background: Evaluation of celiac autoantibodies is a crucial step in the diagnostic algorithm of ... more Background: Evaluation of celiac autoantibodies is a crucial step in the diagnostic algorithm of celiac disease (CD). The need of intestinal biopsy mainly relies on TTG IgA levels (with biopsy still needed if levels are less than 10 times the ULN, subdiagnostic levels [SDLs]). Aim: To evaluate the agreement of serological CD markers between different regional peripheral laboratories (PLs) and our referral regional laboratory (RL) in Salesi Children’s Hospital (Ancona). Methods: Childrenwith a final diagnosis of CD confirmed in our centre (May 2014–April 2015) and a previous (within 1 month) serological evaluation (TTG IgA and DGP IgG) performed in one PLs were included. Levels (times the ULN) of TTG IgA and DGP IgGwere compared between the RL and the PLs. Results: Forty-one subjects (mean age: 6.2 years) with a diagnosis of CD were included. Overall the RL confirmed abnormal CD antibodies detected in PLs in 100% of patients. A small proportion were discordant in TTG IgA levels: 10% with SDLs detected in a PL had diagnostic levels in the RL, while 17% with>10 times the ULN in a PLwere found to have SDLs in the RL, requiring confirmation by biopsy. Bland Altaman analysis suggested that the levels of TTG IgA in the RL was on average 4.8 times higher (SD 14.8) than the levels in the PLs with wide limits of agreement (95% limit of agreement: −33.83 to 24.20 times). Conclusion: In our regional setting the determination of serological CDmarkers in a PLswas overall reliable andwe found a good correlationwithmeasurement in the RL. Howeverwe still consider the confirmation in our RL a fundamental step in the diagnostic process.
Frontiers in Pediatrics, May 19, 2022
Results: Children are seriously penalized both for surgical treatment as well as for the diagnost... more Results: Children are seriously penalized both for surgical treatment as well as for the diagnostic component. In most centers, the pediatric surgical teams have been Morini et al. COVID-19 and Pediatric Surgical Care in Italy integrated with the adult ones and the specificity of training the pediatric operating nursing is in danger of survival. "Emotional" management of the child is not considered by the general management and the child has become again an adults patient of reduced size. Conclusion: A new functional pediatric surgical model needs to be established in general hospitals, including activities for day surgery and outpatient surgery. To support the care of the fragile child, a national health plan for the pediatric surgery is required.
Digestive and Liver Disease, Oct 1, 2016
La Pediatria Medica e Chirurgica
Urothelial bladder neoplasms (UBN) are uncommon in children and are poorly understood. Their mana... more Urothelial bladder neoplasms (UBN) are uncommon in children and are poorly understood. Their management is contentious, and there are currently no pediatric guidelines available, making it difficult to envision a surgical approach that can be defined as the gold standard for the treatment of these diseases. Pneumovesicoscopy, which has already been used to treat other urological diseases, could be a promising treatment option for selected cases of this group of pathologies. We present our experience with three pediatric UBN cases in which pneumovesicoscopy was used for complete excision of a perimeatal papilloma in two cases and biopsy of a botryoid rhabdomyosarcoma in one. The pneumovesicoscopic approach, in our experience, provided a viable alternative technique for the management of selected cases of UBN.
Surgical Endoscopy
Background Pediatric robotic-assisted surgeries have increased in recent years; however, guidance... more Background Pediatric robotic-assisted surgeries have increased in recent years; however, guidance documents are still lacking. This study aimed to develop evidence-based recommendations, or best practice statements when evidence is lacking or inadequate, to assist surgical teams internationally. Methods A joint consensus taskforce of anesthesiologists and surgeons from the Italian Society of Pediatric and Neonatal Anesthesia and Intensive Care (SARNePI) and the Italian Society of Pediatric Surgery (SICP) have identified critical areas and reviewed the available evidence. The taskforce comprised 21 experts representing the fields of anesthesia (n = 11) and surgery (n = 10) from clinical centers performing pediatric robotic surgery in the Italian cities of Ancona, Bologna, Milan, Naples, Padua, Pavia, Perugia, Rome, Siena, and Verona. Between December 2020 and September 2021, three meetings, two Delphi rounds, and a final consensus conference took place. Results During the first plann...
Children (Basel), Mar 15, 2022
This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY
European Urology Supplements, 2018
La Clinica terapeutica, 2017
Survival of preterm infants have dramatically improved over the last decades. Nonetheless, infant... more Survival of preterm infants have dramatically improved over the last decades. Nonetheless, infants born preterm remain vulnerable to many complications, including necrotizing enterocolitis (NEC). The severity of the disease and the mortality rate are directly correlated with decreasing gestational age and birth weight. Despite surgical treatment mortality rate remains very high in extremely premature infants, especially in newborns at the lowest limit of viability. Survival of infants of birth weight (BW) below 750 g has been increasingly reported in recent years, however the overall mortality in extremely low "BW" infants (ELBW) requiring surgery for NEC has not decreased over the past years. We describe our experience with a male preterm infant who survived after an ileostomy procedure for Bell stage II NEC, with improving neuromotor skills at 2 years follow up. Although standard indication to surgery is Bell stage III, in our case the choice of minimal laparotomy, explo...
European urology open science, Oct 1, 2020
Prenatal Diagnosis, 1988
We report the ultrasound prenatal diagnosis a t the 30th week of macroglossia in two sibs with th... more We report the ultrasound prenatal diagnosis a t the 30th week of macroglossia in two sibs with the Wiedemann-Beckwith syndrome; the syndrome was also present in their mother. A study of high resolution chromosomes did not show any anomaly. KEY WORDS Macroglossia Wiedemann-Beckwith syndrome Ultrasound prenatal diagnosis EMG syndrome
International Journal of Medical Robotics and Computer Assisted Surgery, Jun 1, 2023
BackgroundRobot‐assisted approach to UVJ is getting more and more used in pediatric patients.Meth... more BackgroundRobot‐assisted approach to UVJ is getting more and more used in pediatric patients.MethodsIn this retrospective study 26 patients affected by nephro‐urological malformations, robotic‐surgically treated from 2016 and 2021 at 3 Pediatric Surgery Department were included: 3 (11.5%) primary obstructive megaureter, 2 (7.7%) dysplastic kidneys, 3 (11.5%) duplex collecting system, 18 (69.2%) primary vescico‐ureteral reflux (VUR).ResultsMean age at surgery was 6 years old. 22 (84.6%) underwent Lich Gregoire extravesical ureteral reimplantation, 4 (15.4%) total nephroureterectomy. Mean operative time was 230 min. No conversions or intraoperative complications. Median hospital stay was 4 days. There were 4 (15.38%) postoperative complications: 3 (11.54%) persistent VUR and 1 (3.84%) refluxing megaureter. 2 (7.7%) redo‐surgery.ConclusionsRobotic Surgery should be considered a safe and effective technique for treatment of UVJ anomalies in children, because it firstly allows surgeons to approach both upper and lower ureteral ends without modifying trocars’ placement.
Journal of pediatric surgery case reports, 2021
Abstract Echinococcosis is a parasitic zoonosis in which humans are involved as an intermediate h... more Abstract Echinococcosis is a parasitic zoonosis in which humans are involved as an intermediate host. It is a very common pathology in the areas of Eastern Europe and Asia, where the main activity is represented by pastoralism and animal breeding. In humans, the most frequently affected sites are the liver (60–70%) and lungs (20–30%), manifesting themselves with symptoms such as abdominal pain, coughing, dyspnea, hemoptysis, up to cases of anaphylactic shock. In Italy it is not a common disease with an incidence of 2:100.000 inhabitants, and it's extremely rare in pediatric population. In this work we presented a case of a 11-years male patient came for a persistent cough, to whom was found a giant cystic mass in the thorax. Serological tests confirmed the diagnosis of echinococcosis. Patient underwent to thoracotomy to remove the cyst and he begun the antiparasitic therapy. Post-operative outcome was good and the patient is, until now, free of problems. Echinococcosis is a challenging problem for a pediatric surgeon, especially in non-endemic area, not only because it is not a common disease in pediatric population, but also for the surgical management that can presents some difficulties and complications in the post-operative course.
PubMed, Aug 1, 2014
Aim: Aim of the study was to compare multichannel intraluminal impedance (MII)-pH monitoring vers... more Aim: Aim of the study was to compare multichannel intraluminal impedance (MII)-pH monitoring versus pH only, as first-line assessment of gastroesophageal reflux (GER) in children and to define the relation between GER and symptoms as well relation between types of GER and age of children. Methods: All the patients with GER were divided in three groups: A, younger than 24 months, B, older than 24 months with typical symptoms and C, older than 24 months with atypical symptoms. The groups A and C underwent a combined MII-pH recording. The group B underwent a only pH recording. MII-pH measurements were performed in 89 children (63 group A and 26 group C), only pH measurements in 170 cases (group B). Results: Sixty-seven of the 247 pH measurements demonstrated abnormal reflux indices: 25.0% (group A), 28.8% (group B) and 20.8% (group C). The number of the reflux periods and the total reflux index were highest in the patients of the group B, but the number of long reflux periods was highest in the group C. Abnormal values at MII results were found in 36 cases: 41.7% in group A (high number of weakly acid refluxes events) and 45.8% in group C (similar number of acid and weakly acid events). The MII were considered pathological because of high number of reflux episodes and symptom index ≥ 50% respectively in 60.0% and 40.0% of the group A and 27.3% and 62.7% of the group C. Conclusion: MII-pH study must be reserved to patients younger than 2-year old (high probability of weakly acid reflux) and children with atypical symptoms.
PubMed, Jul 1, 1995
Hemangioma of the bladder is a rare benign tumor. Hematuria is the most common symptom of the dis... more Hemangioma of the bladder is a rare benign tumor. Hematuria is the most common symptom of the disease. The Authors report their experience on two isolated cases of bladder hemangioma. The lesions were diagnosed by endoscopy and biopsy. In both cases the hemangiomas were electrocoagulated endoscopically. Follow-up examination after 1 year, has shown complete eradication of the lesion.
Digestive and Liver Disease, Oct 1, 2015
Gastroenterology Research and Practice, 2015
Transumbilical laparoscopic-assisted appendectomy (TULAA) is increasingly being performed worldwi... more Transumbilical laparoscopic-assisted appendectomy (TULAA) is increasingly being performed worldwide. The authors report their experience in the treatment of acute uncomplicated appendicitis in children with TULAA. From January 2008 to December 2012 all types of acute appendicitis were divided, according to the clinical and ultrasonographic findings, into complicated (appendiceal mass/abscess, diffuse peritonitis) and uncomplicated. Complicated appendicitis was treated by open appendectomy (OA). All patients with the suspicion of uncomplicated appendicitis were offered TULAA by all surgeons of the team. Conversion to open or laparoscopic appendectomy (LA) was performed in case of impossibility to complete TULAA, depending on the choice of surgeon. The histopathologic examination of appendix was always performed. 444 children (252 males) with acute appendicitis were treated. The mean age was 9.2 years (range, 2 to 14 years). Primary OA was performed in 144 cases. In 300 patients a transumbilical laparoscopic-assisted approach was performed. TULAA was completed in 252 patients. Conversion to OA was performed in 45 patients and to LA in 3. Conversion was related to the impossibility to adequately expose the appendix in 47 patients and bleeding in 1. The mean operative time for TULAA was 42 minutes. Histopathologic examination of the appendix removed by TULAA showed a phlegmonous/gangrenous type in 92.8% of cases. Among the 252 TULAA there were 11 cases of umbilical wound infection. TULAA is a feasible and effective procedure for uncomplicated appendicitis in children. It combines the advantages of open and laparoscopic technique (low operative time, low complications rate, and excellent cosmetic results).
Gynecological Endocrinology, May 9, 2022
Journal of pediatric surgery case reports, Jun 1, 2018
Gynecological Endocrinology, May 31, 2017
Objective: The authors present their experience in the management of pediatric patients with Herl... more Objective: The authors present their experience in the management of pediatric patients with Herlyn-Werner-Wunderlich syndrome (HWWS) considering clinical classification and anatomical characteristics of the malformation. Methods: All the data of the patient presented at our Pediatric Surgery Unit from February 2010 to August 2015 were collected. According to the type of malformations, patients were divided in 3 groups: A (completely obstructed hemivagina), B (incompletely obstructed hemivagina), and C (communication between the duplicated cervices). Results: Six patients were treated in the study period. The mean age was 9 years (2 months-15 years). According to the characteristics of the HWWS, we had 5 patients in group A, 1 in group B, and none in group C. One-stage surgical treatment was performed in all cases of complete obstruction, but in one case a second look was necessary for a better resection of the septum. At a mean follow-up of 18 months all patients were symptoms free. Conclusions: Prognosis of this malformation is good in case of early diagnosis and treatment. We suggest that when a renal agenesia is diagnosed, the patient needs an ultrasonographic follow-up of the contralateral kidney but also of the genital tract to find each minimal abnormalities, furthermore, a MRI scanning before the onset of menstruation can be necessary.
Digestive and Liver Disease, Oct 1, 2015
Background: Evaluation of celiac autoantibodies is a crucial step in the diagnostic algorithm of ... more Background: Evaluation of celiac autoantibodies is a crucial step in the diagnostic algorithm of celiac disease (CD). The need of intestinal biopsy mainly relies on TTG IgA levels (with biopsy still needed if levels are less than 10 times the ULN, subdiagnostic levels [SDLs]). Aim: To evaluate the agreement of serological CD markers between different regional peripheral laboratories (PLs) and our referral regional laboratory (RL) in Salesi Children’s Hospital (Ancona). Methods: Childrenwith a final diagnosis of CD confirmed in our centre (May 2014–April 2015) and a previous (within 1 month) serological evaluation (TTG IgA and DGP IgG) performed in one PLs were included. Levels (times the ULN) of TTG IgA and DGP IgGwere compared between the RL and the PLs. Results: Forty-one subjects (mean age: 6.2 years) with a diagnosis of CD were included. Overall the RL confirmed abnormal CD antibodies detected in PLs in 100% of patients. A small proportion were discordant in TTG IgA levels: 10% with SDLs detected in a PL had diagnostic levels in the RL, while 17% with>10 times the ULN in a PLwere found to have SDLs in the RL, requiring confirmation by biopsy. Bland Altaman analysis suggested that the levels of TTG IgA in the RL was on average 4.8 times higher (SD 14.8) than the levels in the PLs with wide limits of agreement (95% limit of agreement: −33.83 to 24.20 times). Conclusion: In our regional setting the determination of serological CDmarkers in a PLswas overall reliable andwe found a good correlationwithmeasurement in the RL. Howeverwe still consider the confirmation in our RL a fundamental step in the diagnostic process.
Frontiers in Pediatrics, May 19, 2022
Results: Children are seriously penalized both for surgical treatment as well as for the diagnost... more Results: Children are seriously penalized both for surgical treatment as well as for the diagnostic component. In most centers, the pediatric surgical teams have been Morini et al. COVID-19 and Pediatric Surgical Care in Italy integrated with the adult ones and the specificity of training the pediatric operating nursing is in danger of survival. "Emotional" management of the child is not considered by the general management and the child has become again an adults patient of reduced size. Conclusion: A new functional pediatric surgical model needs to be established in general hospitals, including activities for day surgery and outpatient surgery. To support the care of the fragile child, a national health plan for the pediatric surgery is required.
Digestive and Liver Disease, Oct 1, 2016
La Pediatria Medica e Chirurgica
Urothelial bladder neoplasms (UBN) are uncommon in children and are poorly understood. Their mana... more Urothelial bladder neoplasms (UBN) are uncommon in children and are poorly understood. Their management is contentious, and there are currently no pediatric guidelines available, making it difficult to envision a surgical approach that can be defined as the gold standard for the treatment of these diseases. Pneumovesicoscopy, which has already been used to treat other urological diseases, could be a promising treatment option for selected cases of this group of pathologies. We present our experience with three pediatric UBN cases in which pneumovesicoscopy was used for complete excision of a perimeatal papilloma in two cases and biopsy of a botryoid rhabdomyosarcoma in one. The pneumovesicoscopic approach, in our experience, provided a viable alternative technique for the management of selected cases of UBN.
Surgical Endoscopy
Background Pediatric robotic-assisted surgeries have increased in recent years; however, guidance... more Background Pediatric robotic-assisted surgeries have increased in recent years; however, guidance documents are still lacking. This study aimed to develop evidence-based recommendations, or best practice statements when evidence is lacking or inadequate, to assist surgical teams internationally. Methods A joint consensus taskforce of anesthesiologists and surgeons from the Italian Society of Pediatric and Neonatal Anesthesia and Intensive Care (SARNePI) and the Italian Society of Pediatric Surgery (SICP) have identified critical areas and reviewed the available evidence. The taskforce comprised 21 experts representing the fields of anesthesia (n = 11) and surgery (n = 10) from clinical centers performing pediatric robotic surgery in the Italian cities of Ancona, Bologna, Milan, Naples, Padua, Pavia, Perugia, Rome, Siena, and Verona. Between December 2020 and September 2021, three meetings, two Delphi rounds, and a final consensus conference took place. Results During the first plann...
Children (Basel), Mar 15, 2022
This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY
European Urology Supplements, 2018
La Clinica terapeutica, 2017
Survival of preterm infants have dramatically improved over the last decades. Nonetheless, infant... more Survival of preterm infants have dramatically improved over the last decades. Nonetheless, infants born preterm remain vulnerable to many complications, including necrotizing enterocolitis (NEC). The severity of the disease and the mortality rate are directly correlated with decreasing gestational age and birth weight. Despite surgical treatment mortality rate remains very high in extremely premature infants, especially in newborns at the lowest limit of viability. Survival of infants of birth weight (BW) below 750 g has been increasingly reported in recent years, however the overall mortality in extremely low "BW" infants (ELBW) requiring surgery for NEC has not decreased over the past years. We describe our experience with a male preterm infant who survived after an ileostomy procedure for Bell stage II NEC, with improving neuromotor skills at 2 years follow up. Although standard indication to surgery is Bell stage III, in our case the choice of minimal laparotomy, explo...
European urology open science, Oct 1, 2020