Swandari Paramita | Mulawarman University (original) (raw)

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Papers by Swandari Paramita

ULIN: Jurnal Hutan Tropis, 2024

Madu Heterotrigona itama dikenal sebagai alternatif dalam pengobatan yang sering dijumpai dengan ... more Madu Heterotrigona itama dikenal sebagai alternatif dalam pengobatan yang sering dijumpai dengan langsung dikonsumsi. Kemampuan madu dalam menghambat aktivitas bakteri karena mengandung senyawa antiseptik. Penelitian ini bertujuan untuk mengeksplorasi potensi madu lebah tanpa sengat (kelulut) Heterotrigona itama yang diternakkan pada areal tumbuhan kaliandra dalam menghambat aktivitas bakteri Escherichia coli selama 6 bulan pengamatan (Oktober 2022 – Maret 2023). Penelitian ini menggunakan metode difusi agar untuk menguji sifat antibakteri madu. Prosedur ini meliputi penuangan media nutrient agar ke cawan petri dan dibiarkan mengering. Kemudian, dibuat lubang pada media dan ditambahkan suspensi bakteri. Dilakukan pengujian pada sampel secara intensif selama enam bulan. Kloramfenikol digunakan sebagai kontrol positif dan aquades sebagai kontrol negatif. Hasil menunjukkan bahwa madu lebah tanpa
sengat H. itama efektif dalam menghambat pertumbuhan bakteri E. coli. Sifat antibakteri madu dipengaruhi oleh efek senyawa bioaktif yang dominan.

International Journal of Multidisciplinary, Mar 22, 2024

The Indonesian Biomedical Journal

BACKGROUND: Indonesia's tropical forest is home to around 80% of the world's medicinal pl... more BACKGROUND: Indonesia's tropical forest is home to around 80% of the world's medicinal plants. One of these is Zingiber purpureum, which have traditionally been used to treat joint discomfort, the common cold, and jaundice. The rhizomes of this plant have been suggested to possess antibacterial action in the treatment of infections. In this study, Z. purpureum was screened for antibacterial activity against 13 bacteria (Gram-positive and Gram-negative).METHODS: Z. purpureum rhizomes were obtained and the distillated extracts were made to generate essential oil. The minimum inhibitory concentration (MIC) and Kirby Bauer disk diffusion methods were used to determine the antibacterial activity.RESULTS: All bacteria activity were inhibited by the essential oil of Z. purpureum at concentrations ranging from 2.5 vol% to 10 vol%. However, several bacterias (Escherichia coli, Pseudomonas aeruginosa, and Enterobacter cloacae) were inhibited at the lowest concentration (0.63 vol %), w...

Journal of Applied Pharmaceutical Science

Malaysian Journal of Fundamental and Applied Sciences

Bee pollen has been used for generations to treat various diseases, including diabetes mellitus, ... more Bee pollen has been used for generations to treat various diseases, including diabetes mellitus, because it inhibits alpha glucosidase enzyme. Two major problems suffered by patients with type 2 Diabetes Mellitus (DM) are linked to insulin resistance and impaired insulin secretion. They often occur in patients aged above 30 years and obese patients. High blood glucose and other complications, including increased HBA1C, are some of the risks faced by people with type 2 diabetes mellitus. This study aimed to reveal the efficacy of bee pollen in lowering the HBA1C levels of patients with type 2 DM. Subjects were gave bee pollen kelulut bees to the intervention group, twice a day in the morning during 4 weeks. This study was quasy experimental research. It involved 30 patients who were divided into the intervention group and the control group. Data were analysis determined the differences in the control and intervention groups using the Mann Whitney test. The result of pre- and post-gr...

Malaysian Journal of Medical Sciences

The broader objective of this study is to identify natural materials that might inhibit the sever... more The broader objective of this study is to identify natural materials that might inhibit the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We have focused on stingless bee honey, which has a unique taste that is both sweet and sour and sometimes bitter. We screened 12 samples of honey from 11 species of stingless bees using an angiotensin-converting enzyme 2 (ACE2)-spike protein-binding assay and phytochemical analysis. Ten of the samples showed inhibition above 50% in this assay system. Most of the honey contained tannins, alkaloids, flavonoids, triterpenoids, carotenoids and carbohydrates. Our findings in this in vitro study showed that honey from stingless bees may have a potent effect against SARS-CoV-2 infection by inhibiting the ACE2-spike protein-binding.

3rd International Conference on Food Security Innovation (ICFSI 2019), Sep 9, 2019

Journal of advanced pharmaceutical technology & research, Aug 9, 2022

Cosmetics

The Eupatorium plant has been well used in medication and as a decorative plant. Some studies hav... more The Eupatorium plant has been well used in medication and as a decorative plant. Some studies have reported that this herb has biochemical compounds, such as sesquiterpenes, phenolics, polysaccharides, and pyrrolizidine alkaloids. Thus, it has pharmacological effects, including antifungal, antibacterial, cytotoxic, and antinociceptive properties, that can be utilized for cosmetic purposes. However, only a few published works have summarized the active compounds and the application of Eupatorium plants as cosmetic agents. Therefore, this article aims to review the application of Eupatorium plants as a potential cosmetic agent. The active compounds of Eupatorium are contained in the whole plant, as well as the stems, leaves, roots, and aerial parts (flower, fruit, and seeds). In terms of cosmetic applications, the activities of Eupathorium are antioxidant, anti-tyrosinase, anti-melanin/melanogenesis, anti-acne, and anti-inflammatory. This review aims to contribute to a better understa...

Verdure: Health Science Journal, Oct 5, 2021

IOP Conference Series: Earth and Environmental Science, Apr 1, 2018

Inflammation is a normal process in the human body as a response to injury from healing process. ... more Inflammation is a normal process in the human body as a response to injury from healing process. Meanwhile, chronic inflammation will cause new health problems to patients. Anti-inflammatory agents generally used for those conditions, have several side effects to patients. The aim of this research was to find alternative anti-inflammatory agents, especially from natural sources.Vernonia amygdalina knew locally as " daun afrika " belong to family Apiaceae is one of those potential natural sources for alternative anti-inflammatory agents. This plant is known astraditionalmedicine from East Kalimantanfor health problems caused by the muscle stiffness and used as material in this research. The experimental method of anti-inflammatory measurement using membrane stabilization activity for V. amygdalina leaves extracts. The results showed that significant differences of EC 50 (p<0.05)achieved between indomethacin as the positive control (26.39 ± 2.91 µg/mL) with V. amygdalina leaves extracts for concentration 1% (131.81 ± 2.95 µg/mL) and 10% (62.54 ± 2.05 µg/mL). EC 50 of V.amygdalina leaves extracts showed the potential anti-inflammatory activities. It could be concluded that V. amygdalina leaves extracts to have anti-inflammatory activities, which could be further developed as a new natural source of the anti-inflammatory agents.

Science Journal of Public Health, 2017

Poor indoor air quality may lead to hospital acquired infection. Microbiological parameter is one... more Poor indoor air quality may lead to hospital acquired infection. Microbiological parameter is one of main standards of indoor air quality. The study objective was to investigate microbiological assessment of indoor air of different wards of Takalar County Hospital, South Sulawesi, Indonesia. Four wards were used for sample collection and these included third, second, first and VIP class ward. Room air temperature, humidity, lighting and number of visitor were also observed. Passive air sampling technique using open Petri dishes containing different culture media was employed. Blood agar plate was used for the bacteria, while Sabouraud dextrose agar plates were used for the fungi. Samplings were done twice daily, one in the morning and other in the afternoon. Isolates were identified according to standard methods. Results show that there was second class ward recorded the highest bacterial growth (1,413 cfu/m 3 in the afternoon). The bacteria isolates were Bacillus sp, Enterobacter sp, Staphylococcus aureus, and Staphylococcus epidermidis. Staphylococcus aureus was the predominantly isolated bacterium. For the conclusion, from the reduction noticed in the morning samples, stringent measures such as proper disinfection and regular cleaning, restriction of patient relatives' movement in and out the wards need to be enforced so as to improve the quality of indoor air of hospital wards.