Grigoris Stratakos | National & Kapodistrian University of Athens (original) (raw)

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Papers by Grigoris Stratakos

Journal of Cancer, 2016

Background: Although interventional management of malignant central airway obstruction (mCAO) is ... more Background: Although interventional management of malignant central airway obstruction (mCAO) is well established, its impact on survival and quality of life (QoL) has not been extensively studied. Aim: We prospectively assessed survival, QoL and dyspnea (using validated EORTC questionnaire) in patients with mCAO 1 day before interventional bronchoscopy, 1 week after and every following month, in comparison to patients who declined this approach. Material/Patients/Methods: 36 patients underwent extensive interventional bronchoscopic management as indicated, whereas 12 declined. All patients received full chemotherapy and radiotherapy as indicated. Patients of the 2 groups were matched for age, comorbidities, type of malignancy and level of obstruction. Follow up time was 8.0±8.7 (range 1-38) months. Results: Mean survival for intervention and control group was 10±9 and 4±3 months respectively (p=0.04). QoL improved significantly in intervention group patients up to the 6 th month (p<0.05) not deteriorating for those surviving up to 12 months. Dyspnea decreased in patients of the intervention group 1 month post procedure remaining reduced for survivors over the 12th month. Patients of the control group had worse QoL and dyspnea in all time points. Conclusions: Interventional management of patients with mCAO, may achieve prolonged survival with sustained significant improvement of QoL and dyspnea.

DOAJ (DOAJ: Directory of Open Access Journals), 2011

... 13 Η προσωπική συμβουλή μπορεί να παρέχεται με διάφορους τρόπους: Μέσω video, 14 ... Όμως δεν... more ... 13 Η προσωπική συμβουλή μπορεί να παρέχεται με διάφορους τρόπους: Μέσω video, 14 ... Όμως δεν θεωρούνται όλα τα προγράμματα διακοπής καπνίσματος του διαδικτύου αξιόπιστα εύχρηστα και ... από τη μετά- ανάλυση των Μelvin και συνεργατών η συμβουλευτική έχει βασιστεί ...

Journal of Medical Cases, Oct 2, 2013

Transverse myelitis is a rare, serious complication of Mycoplasma pneumoniae infection. Here we r... more Transverse myelitis is a rare, serious complication of Mycoplasma pneumoniae infection. Here we report a case of acute transverse myelitis in a previously healthy 26-year-old male, during the course of a lower respiratory infection. The diagnosis was based on magnetic resonance imaging findings of the spinal cord and on the quantitative determination of IgM and IgG antibodies against M. pneumoniae in the serum and a positive nested PCR test in the sputum. Diagnostic workout did not reveal any other cause of the neurological symptoms. The patient was treated successfully with intravenous azithomycin and doxycycline. His recovery was progressive and he was discharged without any neurologic sequelae.

DOAJ (DOAJ: Directory of Open Access Journals), Sep 1, 2013

Pulmonary Pharmacology & Therapeutics, Dec 1, 2022

Respiration, 2005

We report on a 26-year-old woman who during early infancy (6 months) suffered from a chemical bur... more We report on a 26-year-old woman who during early infancy (6 months) suffered from a chemical burn of the skin and upper airways due to spill of formic acid powder. Twenty years after the initial injury, she presented with dyspnea and stridor due to severe tracheal stenosis. Several interventional bronchoscopic manipulations were initiated: incision of the stenotic lesion with Nd:YAG laser and dilatation with a valvuloplasty balloon which enabled silicone stent placement which was subsequently kept in place for 3 years. Complications during the 4th year after stenting led to the successful replacement of this stent by two autoexpandable metallic stents covering the total length of the trachea from the subglottic area to the carina. In post-burn inhalation injuries, a complex inflammatory process may be active for many years after the initial insult. These injuries respond to prolonged tracheal stenting and a conservative approach is recommended.

European Respiratory Review, Nov 18, 2020

Therapeutic bronchoscopy modalities may effectively treat difficult central airway problems in bo... more Therapeutic bronchoscopy modalities may effectively treat difficult central airway problems in both malignant and benign diseases. This also involves responsibility for treating related complications. Training in interventional pulmonology is warranted.

American Journal of Respiratory and Critical Care Medicine, Jul 1, 2006

The exact site(s) and pathophysiology of air leakage in patients with primary spontaneous pneumot... more The exact site(s) and pathophysiology of air leakage in patients with primary spontaneous pneumothorax (PSP) are unknown. In one patient with PSP, fluorescein-enhanced autofluorescence thoracoscopy (FEAT) has shown areas of parenchymal abnormality unnoticed during white light thoracoscopy (WLT). Objectives: To prospectively perform and compare WLT and FEAT in patients with spontaneous pneumothorax and in normal subjects. Methods: One-time FEAT and WLT inspection with systematic mapping of semiquantified lesions in 12 consecutive patients with PSP was compared with one-time FEAT and WLT during sequential bilateral thoracoscopy in 17 control subjects. Results: WLT abnormalities (anthracosis, cobblestone malformation, and blebs/bullae) were more prevalent in PSP. FEAT, however, showed high-grade lesions in PSP only, which often were present at areas that were normal, or that only showed anthracosis at WLT. When blebs/bullae were present, bleb-associated FEAT abnormalities were only present in two. Actual fluorescein leakage was seen in two patients with PSP. Conclusions: Lungs in patients with PSP show significantly more abnormalities at WLT when compared with normal subjects. Highgrade FEAT lesions were exclusively present in PSP, and predominantly at lung zones that appeared normal at white light inspection. These findings suggest that significant parenchymal abnormalities are not limited to lesions visible during WLT, such as blebs and bullae.

The Korean Journal of Thoracic and Cardiovascular Surgery, Aug 5, 2018

Radiofrequency ablation is an effective treatment for atrial fibrillation. Pulmonary vein stenosi... more Radiofrequency ablation is an effective treatment for atrial fibrillation. Pulmonary vein stenosis/occlusion is one of its rare complications. Herein, the case of a 50-year-old man with hemoptysis and migratory pulmonary infiltrations after transcatheter radiofrequency ablation for atrial fibrillation is presented. Initially, pneumonia, interstitial pulmonary disease, or lung cancer was suspected, but wedge resection revealed hemorrhagic infiltrations. Chest computed tomography pulmonary angiography detected no left superior pulmonary vein due to its total occlusion, and left upper lobectomy was performed. Post-ablation pulmonary vein occlusion must be strongly suspected in cases of migratory pulmonary infiltrations and/or hemoptysis.

Advances in respiratory medicine, Sep 2, 2021

This article is available in open access under Creative Common Attribution-Non-Commercial-No Deri... more This article is available in open access under Creative Common Attribution-Non-Commercial-No Derivatives 4.0 International (CC BY-NC-ND 4.0) license, allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially.

Life, Dec 13, 2022

This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY

Journal of Personalized Medicine

Despite that COPD remains one of the most common respiratory diseases worldwide, it can be manage... more Despite that COPD remains one of the most common respiratory diseases worldwide, it can be managed effectively with certain treatments and, more importantly, be prevented by the early implementation of various measures. The pathology and pathophysiology of this disease continue to be studied, with new pharmacological and invasive therapies emerging. In this consensus paper, the Working Group of the Hellenic Thoracic Society aimed to consolidate the up-to-date information and new advances in the treatment of COPD. Local and international data on its prevalence are presented, with revised strategies on the diagnostic approach and the evaluation of risk assessment and disease severity classification. Emphasis is placed on the management and therapy of patients with COPD, covering both common principles, specialized modalities, and algorithms to distinguish between home care and the need for hospitalization. Although pharmacological treatment is commonly recognized in COPD, an integrati...

Interactive CardioVascular and Thoracic Surgery, 2017

International Journal of Clinical Practice, 2021

Endoluminal therapy either by dilatation, scar tissue resection or stent insertion is an establis... more Endoluminal therapy either by dilatation, scar tissue resection or stent insertion is an established treatment for non‐malignant airway stenosis although the surgical approach is still considered the “gold standard.” No clear consensus exists on the structured role of each modality.