Alexander Pulido-Rojano | Universidad Simón Bolívar (original) (raw)

Papers by Alexander Pulido-Rojano

Research paper thumbnail of Methodological design for the prevention of risk in production processes

This paper proposes a methodological design based on the development, creation, adaptation and im... more This paper proposes a methodological design based on the development, creation, adaptation and implementation of some analysis tools and the deployment of the risk management process content in standard ISO 31000. This allows for the design of a monitoring and quality control system of critical variables associated with equipment and operating conditions for the purpose of identifying and mitigating sources diversions product specifications. It also seeks to harmonize work philosophies with international management standards. The validation was performed by an industrial company from the city of Barranquilla. The content of this paper provides professionals and industry with a way to address and improve the capacity of any type of manufacturing process in any organization through standardized steps.

Research paper thumbnail of A multiobjective approach for optimization of the multihead weighing process

Packaging technology can be of strategic importance to a company, as it can be a key to competiti... more Packaging technology can be of strategic importance to a company, as it can be a key to competitive advantage in the modern food industry. A multihead weighing process is a packaging process based on the sum of weights from several individual hoppers. The final quality of the packaged product in a modern automated food packing system should fulfill two objectives —the quality of the packaging process itself and the sensory quality of the packaged food. The first one is often related to the proximity of the total weight to a nominal value of sale and to the variability of the packaging process, and the second one can be achieved by minimizing the total residence time of the food in the packing system. In this paper, we jointly address both objectives through multiobjective programming. More precisely, a biobjective algorithm is developed, in which a subset of hoppers is selected from the set of available ones at each packing operation, in such a way that the relative importance of both aforementioned objectives is dynamically managed and adjusted. We conduct numerical experiments to examine the quality of the solutions being produced.

Research paper thumbnail of Mitigation of defects in products manufactured

This paper proposes a process in which some statistical tools of quality and risk management proc... more This paper proposes a process in which some statistical tools of quality and risk management process contained in the NTC 5254 and ISO 31000 are used. The objective is to propose a set of simple steps to reduce the defects that occur in a production system. The proposal seeks to be a guide for combining quality tools and management standards while taking into account the operating characteristics of the company. The proposed process starts with the identification of products and processes critical to the organization within its product line and ends with review and monitoring of the actions proposed to mitigate the sources of nonconformities identified. It seeks to show how to implement a process of risk management in production systems and manufacturing.

Research paper thumbnail of Cross-Cultural Primary Care: A Patient-Based Approach

... In today's multicultural society, assuring quality health care for all persons requires ... more ... In today's multicultural society, assuring quality health care for all persons requires that physicians understand how each patient's sociocultural background affects his or her health beliefs and behaviors. Cross-cultural curricula have been developed to address these issues but ...

Research paper thumbnail of Flavonoid Genes in Petunia: Addition of a Limited Number of Gene Copies May Lead to a Suppression of Gene Expression

Plant Cell, 1990

To evaluate the effect of increased expression of genes involved in flower pigmentation, addition... more To evaluate the effect of increased expression of genes involved in flower pigmentation, additional dihydroflavonol-4-reductase (DFR) or chalcone synthase (CHS) genes were transferred to petunia. In most transformants, the increased expression had no measurable effect on floral pigmentation. Surprisingly, however, in up to 25% of the transformants, a reduced floral pigmentation, accompanied by a dramatic reduction of DFR or CHS gene expression, respectively, was observed. This phenomenon was obtained with both chimeric gene constructs and intact CHS genomic clones. The reduction in gene expression was independent of the promoter driving transcription of the transgene and involved both the endogenous gene and the homologous transgene. The gene-specific collapse in expression was obtained even after introduction of only a single gene copy. The similarity between the sense transformants and regulatory CHS mutants suggests that this mechanism of gene silencing may operate in naturally occurring regulatory circuits.

Research paper thumbnail of Methodological design for the prevention of risk in production processes

This paper proposes a methodological design based on the development, creation, adaptation and im... more This paper proposes a methodological design based on the development, creation, adaptation and implementation of some analysis tools and the deployment of the risk management process content in standard ISO 31000. This allows for the design of a monitoring and quality control system of critical variables associated with equipment and operating conditions for the purpose of identifying and mitigating sources diversions product specifications. It also seeks to harmonize work philosophies with international management standards. The validation was performed by an industrial company from the city of Barranquilla. The content of this paper provides professionals and industry with a way to address and improve the capacity of any type of manufacturing process in any organization through standardized steps.

Research paper thumbnail of A multiobjective approach for optimization of the multihead weighing process

Packaging technology can be of strategic importance to a company, as it can be a key to competiti... more Packaging technology can be of strategic importance to a company, as it can be a key to competitive advantage in the modern food industry. A multihead weighing process is a packaging process based on the sum of weights from several individual hoppers. The final quality of the packaged product in a modern automated food packing system should fulfill two objectives —the quality of the packaging process itself and the sensory quality of the packaged food. The first one is often related to the proximity of the total weight to a nominal value of sale and to the variability of the packaging process, and the second one can be achieved by minimizing the total residence time of the food in the packing system. In this paper, we jointly address both objectives through multiobjective programming. More precisely, a biobjective algorithm is developed, in which a subset of hoppers is selected from the set of available ones at each packing operation, in such a way that the relative importance of both aforementioned objectives is dynamically managed and adjusted. We conduct numerical experiments to examine the quality of the solutions being produced.

Research paper thumbnail of Mitigation of defects in products manufactured

This paper proposes a process in which some statistical tools of quality and risk management proc... more This paper proposes a process in which some statistical tools of quality and risk management process contained in the NTC 5254 and ISO 31000 are used. The objective is to propose a set of simple steps to reduce the defects that occur in a production system. The proposal seeks to be a guide for combining quality tools and management standards while taking into account the operating characteristics of the company. The proposed process starts with the identification of products and processes critical to the organization within its product line and ends with review and monitoring of the actions proposed to mitigate the sources of nonconformities identified. It seeks to show how to implement a process of risk management in production systems and manufacturing.

Research paper thumbnail of Cross-Cultural Primary Care: A Patient-Based Approach

... In today's multicultural society, assuring quality health care for all persons requires ... more ... In today's multicultural society, assuring quality health care for all persons requires that physicians understand how each patient's sociocultural background affects his or her health beliefs and behaviors. Cross-cultural curricula have been developed to address these issues but ...

Research paper thumbnail of Flavonoid Genes in Petunia: Addition of a Limited Number of Gene Copies May Lead to a Suppression of Gene Expression

Plant Cell, 1990

To evaluate the effect of increased expression of genes involved in flower pigmentation, addition... more To evaluate the effect of increased expression of genes involved in flower pigmentation, additional dihydroflavonol-4-reductase (DFR) or chalcone synthase (CHS) genes were transferred to petunia. In most transformants, the increased expression had no measurable effect on floral pigmentation. Surprisingly, however, in up to 25% of the transformants, a reduced floral pigmentation, accompanied by a dramatic reduction of DFR or CHS gene expression, respectively, was observed. This phenomenon was obtained with both chimeric gene constructs and intact CHS genomic clones. The reduction in gene expression was independent of the promoter driving transcription of the transgene and involved both the endogenous gene and the homologous transgene. The gene-specific collapse in expression was obtained even after introduction of only a single gene copy. The similarity between the sense transformants and regulatory CHS mutants suggests that this mechanism of gene silencing may operate in naturally occurring regulatory circuits.