Alayna P Tackett | University of Southern California (original) (raw)

Papers by Alayna P Tackett

Research paper thumbnail of A Proposed Collaboration against Big Tobacco: Common Ground between the Vaping and Public Health Community in the United States

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, Jan 26, 2015

An unfortunate conflict is underway between the public health community and the vaping community ... more An unfortunate conflict is underway between the public health community and the vaping community over e-cigarettes' harmfulness or lack thereof. This conflict is made worse by an information vacuum that is being filled by vocal members on both sides of the debate; a perceived lack of credibility of public health officials among those in the vaping community; the tobacco industry's recent involvement in e-cigarettes; and the constant evolution of different styles and types of e-cigarettes. This conflict is avoidable; common ground exists. If both groups rally around what is in their own and the public's best interest-the end of combustible tobacco-all will benefit significantly. If not, the result may be missed opportunities, misguided alliances, and ultimately-poorer public health.

Research paper thumbnail of Illness Uncertainty, Global Psychological Distress, and Posttraumatic Stress in Pediatric Cancer: A Preliminary Examination Using a Path Analysis Approach

Journal of Pediatric Psychology, 2015

To investigate the relationship of illness uncertainty (IU) to global psychological distress (GP... more To investigate the relationship of illness uncertainty (IU) to global psychological distress (GPD) and posttraumatic stress symptomatology (PTSS) using a path analysis approach. Participants were 105 caregivers (MAge = 36.9 years, standard deviation [SD] = 8.7) of children (MAge = 8.6 years, SD = 5.0) with newly diagnosed cancer. A path analysis model examined the indirect and direct effects of each IU subscale on PTSS through GPD. RESULTS: The final model accounted for 47.30% of the variance in PTSS, and the ambiguity facet of IU had a significant indirect effect on PTSS through GPD. Lack of clarity and unpredictability were not significant predictors. CONCLUSIONS: Ambiguity experienced by parents may be salient in the development of PTSS. Future research should examine these relationships longitudinally in larger samples to better understand adjustment in parents of children with cancer.

Research paper thumbnail of Models of Resilience: Developing Psychosocial Interventions for Parents of Children with Chronic Health Conditions

Research paper thumbnail of Adolescents and Young Adults With Asthma: Self-Identification, Adjustment and Psychological Distress

Journal of Developmental & Behavioral Pediatrics

Research paper thumbnail of Characterizing early psychosocial functioning of parents of children with moderate to severe genital ambiguity due to a disorder of sex development (DSD)

The Journal of Urology, 2015

We examined the psychosocial characteristics of parents of children with disorders of sex develop... more We examined the psychosocial characteristics of parents of children with disorders of sex development at early presentation to a disorders of sex development clinic. Parental anxiety, depression, quality of life, illness uncertainty and posttraumatic stress symptoms were assessed. Additionally we evaluated the relationship of assigned child gender to parental outcomes. A total of 51 parents of children with ambiguous or atypical genitalia were recruited from 7 centers specializing in treatment of disorders of sex development. At initial assessment no child had undergone genitoplasty. Parents completed the Cosmetic Appearance Rating Scale, Beck Anxiety Inventory, Beck Depression Inventory, SF-36, Parent Perception of Uncertainty Scale and Impact of Event Scale-Revised. A large percentage of parents (54.5%) were dissatisfied with the genital appearance of their child, and a small but significant percentage reported symptoms of anxiety, depression, diminished quality of life, uncertainty and posttraumatic stress. Few gender differences emerged. Although many parents function well, a subset experience significant psychological distress around the time of diagnosis of a disorder of sex development in their child. Early screening to assess the need for psychosocial interventions is warranted.

Research paper thumbnail of Self-esteem, Self-focused Attention, and the Mediating Role of Fear of Negative Evaluation in College Students With and Without Asthma

Journal of American college health : J of ACH, Jan 7, 2015

The current study investigated the mediating role of fear of negative evaluation on the relations... more The current study investigated the mediating role of fear of negative evaluation on the relationship between self-focused attention and self-esteem among college students with and without asthma. Young adults with (N = 148) and without (N = 530) childhood-onset asthma were recruited from a college student population. Self-focused attention and fear of negative evaluation measures were completed. Participants also answered questions about inclusion in a social activity. Higher levels of self-focused attention and fear of negative evaluation were associated with lower self-esteem in both groups within the context of social activity participation. Fear of negative evaluation mediated the relationship between self-consciousness and self-esteem. No significant differences were found between groups. Findings indicate significant relationships among self-focused attention, fear of negative evaluation, and self-esteem in the context of social activity participation. Further examination of s...

Research paper thumbnail of Caregivers' interest in using smokeless tobacco products: Novel methods that may reduce children's exposure to secondhand smoke

Journal of health psychology, Jan 6, 2015

The study examined caregivers' interest in using potentially reduced exposure tobacco product... more The study examined caregivers' interest in using potentially reduced exposure tobacco products for smoking cessation, reduction, and to help them not smoke in places such as around their child, as all three methods would potentially lead to reduced secondhand smoke exposure for their children. A sample of 136 caregivers completed carbon monoxide testing to assess smoking status and a brief survey. Few caregivers had ever used potentially reduced exposure tobacco products (<1%), but a majority were interested in trying them as means of smoking reduction (54%), to quit/stay quit from smoking (51%), and to help them not smoke around their child or in the home (55%). Caregivers less motivated to quit smoking and with no home smoking ban were more interested in using potentially reduced exposure tobacco products to help them quit/stay quit from smoking (p < .05).

Research paper thumbnail of Parent Medication Barriers Scale (PMBS): A Preliminary Investigation of Factor Structures with Hematopoietic Stem Cell Transplant Recipients

Children's Health Care, 2014

ABSTRACT Purpose. To examine caregiver barriers to medication adherence and the factor structure ... more ABSTRACT Purpose. To examine caregiver barriers to medication adherence and the factor structure of the Parent Medication Barrier Scale (PMBS), a self-report measure, in children with hematopoietic stem cell transplantation (HSCT). Methods. Caregivers of 81 children/adolescents with HSCT completed the PMBS. Results. Internal consistency in the current sample was acceptable (α = .85); subscale reliability ranged from .34 to .72. Criterion validity was examined with the Medical Adherence Measure. Confirmatory factor analyses yielded a 2-factor solution and the factors were found to be moderately reliable (α = .77; α = .67). Conclusions. Results suggest that adapting the PMBS measure to create a young child HSCT-specific caregiver version is warranted.

Research paper thumbnail of Postpartum depression on the neonatal intensive care unit: current perspectives

International Journal of Women's Health, 2014

Research paper thumbnail of Effectiveness of Electronic Aids for Smoking Cessation

Current Cardiovascular Risk Reports, 2013

Tobacco use continues to be the leading cause of preventable death in the world, and though curre... more Tobacco use continues to be the leading cause of preventable death in the world, and though current evidencebased approaches have substantially reduced rates of smoking, these rates remain disturbingly high. Two recent technological advancements, the electronic cigarette (e-cigarette) and mobile health (mHealth) interventions, may offer smokers an alternative way to quit smoking. E-cigarettes continue to be fiercely debated. Preliminary evidence suggests that e-cigarettes are likely much safer than regular cigarettes and are helpful to some smokers as a means of reducing or quitting smoking. Questions, however, still remain as to how they will affect overall public health-if they will be used as a "gateway" product or reduce motivation to quit smoking, to name but a few. Similarly, mHealth interventions appear to be effective and accepted by users. However, mobile 'apps' have yet to be tested in randomized trials and there are concerns about violations of users privacy and state jurisdictions.

Research paper thumbnail of Biochemically verified smoking cessation and vaping beliefs among vape store customers

Addiction, 2015

To evaluate biochemically verified smoking status, and electronic nicotine delivery systems (ENDS... more To evaluate biochemically verified smoking status, and electronic nicotine delivery systems (ENDS) use behaviors and beliefs among a sample of customers from vapor stores (stores specializing in ENDS). A cross-sectional survey of 215 adult vapor store customers at four retail locations in the Midwestern United States; a subset of participants (n=181) also completed exhaled carbon monoxide (CO) testing to verify smoking status. Outcomes evaluated included ENDS preferences, harm beliefs, use behaviors, smoking history and current biochemically verified smoking status. Most customers reported starting ENDS as a means of smoking cessation (86%), using newer generation devices (89%), vaping non-tobacco/non-menthol flavors (72%), and using e-liquid with nicotine strengths of ≤20 mg/ml (72%). There was a high rate of switching (91.4%) to newer generation ENDS among those who started with a first generation product. Exhaled CO readings confirmed that 66% of the tested sample had quit smoking. Among those who continued to smoke, mean cigarettes per day decreased from 22.1 to 7.5 (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;.001). People who reported vaping longer (OR=4.7, 95% CI = 2.0-10.8), using newer generation devices (OR=3.0, 95% CI = 1.0-8.4) and using non-tobacco and non-menthol flavors (OR=2.6, 95% CI = 1.1-6.1) were more likely to have quit smoking. Among vapor store customers in the US who use electronic nicotine delivery devices to stop smoking, vaping longer, using newer generation devices, and using non-tobacco and non-menthol flavored e-liquid appear to be associated with higher rates of smoking cessation. This article is protected by copyright. All rights reserved.

Research paper thumbnail of Psychosocial Assessment Tool 2.0_General: Validity of a psychosocial risk screener in a pediatric kidney transplant sample

Pediatric Transplantation, 2011

To present the preliminary psychometric properties of the PAT2.0_GEN, a brief, caregiver complete... more To present the preliminary psychometric properties of the PAT2.0_GEN, a brief, caregiver completed screener of psychosocial for children who were recipients of kidney transplants. Caregivers of 45 children and adolescents with kidney transplants completed the PAT2.0_GEN and the PedsQL. Internal consistency and predictive validity of the PAT2.0 were examined. Internal consistency for the PAT2.0_GEN Total score was strong. Internal consistency for the PAT2.0_GEN subscales ranged from 0.31 to 0.82. Evidence supporting convergent validity was observed; higher PAT2.0_GEN scores were significantly associated with lower caregiver- and self-rated patient quality of life and poorer family communication. PAT2.0_GEN scores were also associated with an increased likelihood that a patient received or had been independently referred for psychological services within two yr of completing the PAT2.0_GEN. The PAT2.0_GEN Total score is a promising screening tool for psychosocial risk in the pediatric kidney transplant population.

Research paper thumbnail of System for integrated adherence monitoring: Real-time non-adherence risk assessment in pediatric kidney transplantation

Pediatric Transplantation, 2012

This study reports initial results of the development of the SIAM, a non-adherence risk assessmen... more This study reports initial results of the development of the SIAM, a non-adherence risk assessment system for tacrolimus and sirolimus for the pediatric kidney transplant population. Forty-eight youths between 10 and 25 yr of age diagnosed with chronic kidney disease or a kidney transplant used an electronic pill bottle (EM; time stamps each bottle opening) to dispense their medication for at least 30 days or until their next clinic appointment. Youth also completed a self-report adherence measure, and standard deviations were calculated for the last four medication serum trough levels obtained for each patient. Estimation models were developed for each medication (i.e., SIAM(TACRO) and SIAM(SIRO) ) to assign weights to these clinically available adherence measures (self-report and trough levels) for the calculation of a non-adherence risk composite score. SIAM(TACRO) models included both self-report and tacrolimus trough levels and significantly predicted EM. For sirolimus, the model predictive of adherence as measured by EM consisted of the standard deviation of sirolimus trough levels only (SIAM(SIRO) ). Non-adherence risk can be effectively assessed using clinically available assessment tools. However, the best methods for using self-report and trough levels to predict non-adherence likely differ based on the medication for which adherence is being assessed.

Research paper thumbnail of Effects of Duration of Electronic Cigarette Use

Nicotine & Tobacco Research, 2014

This study examined the effect of duration electronic cigarette (e-cigarette) use on e-cigarette ... more This study examined the effect of duration electronic cigarette (e-cigarette) use on e-cigarette dependence, frequency of use, and strength of nicotine solution as well as number of cigarettes smoked per day. Individuals were recruited at e-cigarette retail locations in a large Midwestern metropolitan city of the United States in July 2013. A total of 159 participants completed a brief 29-item self-report measure that assessed behaviors and perceptions of use. The mean age of the participants was 35.8 years; 84.4% were White, and 53.7% were male. Increased duration of e-cigarette use was associated with fewer cigarettes smoked per day and differing patterns of dependence to e-cigarettes contingent upon smoking history. Additionally, increased duration of e-cigarette use was associated with increased frequency of use; however, this finding became nonsignificant when current tobacco cigarette use was accounted for, suggesting that individuals may increase e-cigarette use frequency as they decrease cigarette use. Overall, e-cigarette users tended to decrease the strength of nicotine in their e-cigarette products regardless of duration of use. Although preliminary in nature, this study identifies several factors that are important to consider when examining the effects of prolonged e-cigarette use. The implications of the current results should be informative to future studies that examine these variables in longitudinal designs.

Research paper thumbnail of Assessing Psychosocial Risk in Pediatric Inflammatory Bowel Disease

Journal of Pediatric Gastroenterology and Nutrition, 2014

Purpose: To present the preliminary psychometric properties of the Psychosocial Assessment Tool 2... more Purpose: To present the preliminary psychometric properties of the Psychosocial Assessment Tool 2.0_General (PAT2.0_GEN), a brief screener for psychosocial risk in families of children with Inflammatory Bowel Disease (IBD).

Research paper thumbnail of Which Nicotine Products Are Gateways to Regular Use?

American Journal of Preventive Medicine, 2015

Background: The potential for emerging tobacco products (ETPs) to be gateway products for further... more Background: The potential for emerging tobacco products (ETPs) to be gateway products for further tobacco use among youth is of significant concern.

Research paper thumbnail of A Proposed Collaboration against Big Tobacco: Common Ground between the Vaping and Public Health Community in the United States

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, Jan 26, 2015

An unfortunate conflict is underway between the public health community and the vaping community ... more An unfortunate conflict is underway between the public health community and the vaping community over e-cigarettes' harmfulness or lack thereof. This conflict is made worse by an information vacuum that is being filled by vocal members on both sides of the debate; a perceived lack of credibility of public health officials among those in the vaping community; the tobacco industry's recent involvement in e-cigarettes; and the constant evolution of different styles and types of e-cigarettes. This conflict is avoidable; common ground exists. If both groups rally around what is in their own and the public's best interest-the end of combustible tobacco-all will benefit significantly. If not, the result may be missed opportunities, misguided alliances, and ultimately-poorer public health.

Research paper thumbnail of Illness Uncertainty, Global Psychological Distress, and Posttraumatic Stress in Pediatric Cancer: A Preliminary Examination Using a Path Analysis Approach

Journal of Pediatric Psychology, 2015

To investigate the relationship of illness uncertainty (IU) to global psychological distress (GP... more To investigate the relationship of illness uncertainty (IU) to global psychological distress (GPD) and posttraumatic stress symptomatology (PTSS) using a path analysis approach. Participants were 105 caregivers (MAge = 36.9 years, standard deviation [SD] = 8.7) of children (MAge = 8.6 years, SD = 5.0) with newly diagnosed cancer. A path analysis model examined the indirect and direct effects of each IU subscale on PTSS through GPD. RESULTS: The final model accounted for 47.30% of the variance in PTSS, and the ambiguity facet of IU had a significant indirect effect on PTSS through GPD. Lack of clarity and unpredictability were not significant predictors. CONCLUSIONS: Ambiguity experienced by parents may be salient in the development of PTSS. Future research should examine these relationships longitudinally in larger samples to better understand adjustment in parents of children with cancer.

Research paper thumbnail of Models of Resilience: Developing Psychosocial Interventions for Parents of Children with Chronic Health Conditions

Research paper thumbnail of Adolescents and Young Adults With Asthma: Self-Identification, Adjustment and Psychological Distress

Journal of Developmental & Behavioral Pediatrics

Research paper thumbnail of Characterizing early psychosocial functioning of parents of children with moderate to severe genital ambiguity due to a disorder of sex development (DSD)

The Journal of Urology, 2015

We examined the psychosocial characteristics of parents of children with disorders of sex develop... more We examined the psychosocial characteristics of parents of children with disorders of sex development at early presentation to a disorders of sex development clinic. Parental anxiety, depression, quality of life, illness uncertainty and posttraumatic stress symptoms were assessed. Additionally we evaluated the relationship of assigned child gender to parental outcomes. A total of 51 parents of children with ambiguous or atypical genitalia were recruited from 7 centers specializing in treatment of disorders of sex development. At initial assessment no child had undergone genitoplasty. Parents completed the Cosmetic Appearance Rating Scale, Beck Anxiety Inventory, Beck Depression Inventory, SF-36, Parent Perception of Uncertainty Scale and Impact of Event Scale-Revised. A large percentage of parents (54.5%) were dissatisfied with the genital appearance of their child, and a small but significant percentage reported symptoms of anxiety, depression, diminished quality of life, uncertainty and posttraumatic stress. Few gender differences emerged. Although many parents function well, a subset experience significant psychological distress around the time of diagnosis of a disorder of sex development in their child. Early screening to assess the need for psychosocial interventions is warranted.

Research paper thumbnail of Self-esteem, Self-focused Attention, and the Mediating Role of Fear of Negative Evaluation in College Students With and Without Asthma

Journal of American college health : J of ACH, Jan 7, 2015

The current study investigated the mediating role of fear of negative evaluation on the relations... more The current study investigated the mediating role of fear of negative evaluation on the relationship between self-focused attention and self-esteem among college students with and without asthma. Young adults with (N = 148) and without (N = 530) childhood-onset asthma were recruited from a college student population. Self-focused attention and fear of negative evaluation measures were completed. Participants also answered questions about inclusion in a social activity. Higher levels of self-focused attention and fear of negative evaluation were associated with lower self-esteem in both groups within the context of social activity participation. Fear of negative evaluation mediated the relationship between self-consciousness and self-esteem. No significant differences were found between groups. Findings indicate significant relationships among self-focused attention, fear of negative evaluation, and self-esteem in the context of social activity participation. Further examination of s...

Research paper thumbnail of Caregivers' interest in using smokeless tobacco products: Novel methods that may reduce children's exposure to secondhand smoke

Journal of health psychology, Jan 6, 2015

The study examined caregivers' interest in using potentially reduced exposure tobacco product... more The study examined caregivers' interest in using potentially reduced exposure tobacco products for smoking cessation, reduction, and to help them not smoke in places such as around their child, as all three methods would potentially lead to reduced secondhand smoke exposure for their children. A sample of 136 caregivers completed carbon monoxide testing to assess smoking status and a brief survey. Few caregivers had ever used potentially reduced exposure tobacco products (<1%), but a majority were interested in trying them as means of smoking reduction (54%), to quit/stay quit from smoking (51%), and to help them not smoke around their child or in the home (55%). Caregivers less motivated to quit smoking and with no home smoking ban were more interested in using potentially reduced exposure tobacco products to help them quit/stay quit from smoking (p < .05).

Research paper thumbnail of Parent Medication Barriers Scale (PMBS): A Preliminary Investigation of Factor Structures with Hematopoietic Stem Cell Transplant Recipients

Children's Health Care, 2014

ABSTRACT Purpose. To examine caregiver barriers to medication adherence and the factor structure ... more ABSTRACT Purpose. To examine caregiver barriers to medication adherence and the factor structure of the Parent Medication Barrier Scale (PMBS), a self-report measure, in children with hematopoietic stem cell transplantation (HSCT). Methods. Caregivers of 81 children/adolescents with HSCT completed the PMBS. Results. Internal consistency in the current sample was acceptable (α = .85); subscale reliability ranged from .34 to .72. Criterion validity was examined with the Medical Adherence Measure. Confirmatory factor analyses yielded a 2-factor solution and the factors were found to be moderately reliable (α = .77; α = .67). Conclusions. Results suggest that adapting the PMBS measure to create a young child HSCT-specific caregiver version is warranted.

Research paper thumbnail of Postpartum depression on the neonatal intensive care unit: current perspectives

International Journal of Women's Health, 2014

Research paper thumbnail of Effectiveness of Electronic Aids for Smoking Cessation

Current Cardiovascular Risk Reports, 2013

Tobacco use continues to be the leading cause of preventable death in the world, and though curre... more Tobacco use continues to be the leading cause of preventable death in the world, and though current evidencebased approaches have substantially reduced rates of smoking, these rates remain disturbingly high. Two recent technological advancements, the electronic cigarette (e-cigarette) and mobile health (mHealth) interventions, may offer smokers an alternative way to quit smoking. E-cigarettes continue to be fiercely debated. Preliminary evidence suggests that e-cigarettes are likely much safer than regular cigarettes and are helpful to some smokers as a means of reducing or quitting smoking. Questions, however, still remain as to how they will affect overall public health-if they will be used as a "gateway" product or reduce motivation to quit smoking, to name but a few. Similarly, mHealth interventions appear to be effective and accepted by users. However, mobile 'apps' have yet to be tested in randomized trials and there are concerns about violations of users privacy and state jurisdictions.

Research paper thumbnail of Biochemically verified smoking cessation and vaping beliefs among vape store customers

Addiction, 2015

To evaluate biochemically verified smoking status, and electronic nicotine delivery systems (ENDS... more To evaluate biochemically verified smoking status, and electronic nicotine delivery systems (ENDS) use behaviors and beliefs among a sample of customers from vapor stores (stores specializing in ENDS). A cross-sectional survey of 215 adult vapor store customers at four retail locations in the Midwestern United States; a subset of participants (n=181) also completed exhaled carbon monoxide (CO) testing to verify smoking status. Outcomes evaluated included ENDS preferences, harm beliefs, use behaviors, smoking history and current biochemically verified smoking status. Most customers reported starting ENDS as a means of smoking cessation (86%), using newer generation devices (89%), vaping non-tobacco/non-menthol flavors (72%), and using e-liquid with nicotine strengths of ≤20 mg/ml (72%). There was a high rate of switching (91.4%) to newer generation ENDS among those who started with a first generation product. Exhaled CO readings confirmed that 66% of the tested sample had quit smoking. Among those who continued to smoke, mean cigarettes per day decreased from 22.1 to 7.5 (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;.001). People who reported vaping longer (OR=4.7, 95% CI = 2.0-10.8), using newer generation devices (OR=3.0, 95% CI = 1.0-8.4) and using non-tobacco and non-menthol flavors (OR=2.6, 95% CI = 1.1-6.1) were more likely to have quit smoking. Among vapor store customers in the US who use electronic nicotine delivery devices to stop smoking, vaping longer, using newer generation devices, and using non-tobacco and non-menthol flavored e-liquid appear to be associated with higher rates of smoking cessation. This article is protected by copyright. All rights reserved.

Research paper thumbnail of Psychosocial Assessment Tool 2.0_General: Validity of a psychosocial risk screener in a pediatric kidney transplant sample

Pediatric Transplantation, 2011

To present the preliminary psychometric properties of the PAT2.0_GEN, a brief, caregiver complete... more To present the preliminary psychometric properties of the PAT2.0_GEN, a brief, caregiver completed screener of psychosocial for children who were recipients of kidney transplants. Caregivers of 45 children and adolescents with kidney transplants completed the PAT2.0_GEN and the PedsQL. Internal consistency and predictive validity of the PAT2.0 were examined. Internal consistency for the PAT2.0_GEN Total score was strong. Internal consistency for the PAT2.0_GEN subscales ranged from 0.31 to 0.82. Evidence supporting convergent validity was observed; higher PAT2.0_GEN scores were significantly associated with lower caregiver- and self-rated patient quality of life and poorer family communication. PAT2.0_GEN scores were also associated with an increased likelihood that a patient received or had been independently referred for psychological services within two yr of completing the PAT2.0_GEN. The PAT2.0_GEN Total score is a promising screening tool for psychosocial risk in the pediatric kidney transplant population.

Research paper thumbnail of System for integrated adherence monitoring: Real-time non-adherence risk assessment in pediatric kidney transplantation

Pediatric Transplantation, 2012

This study reports initial results of the development of the SIAM, a non-adherence risk assessmen... more This study reports initial results of the development of the SIAM, a non-adherence risk assessment system for tacrolimus and sirolimus for the pediatric kidney transplant population. Forty-eight youths between 10 and 25 yr of age diagnosed with chronic kidney disease or a kidney transplant used an electronic pill bottle (EM; time stamps each bottle opening) to dispense their medication for at least 30 days or until their next clinic appointment. Youth also completed a self-report adherence measure, and standard deviations were calculated for the last four medication serum trough levels obtained for each patient. Estimation models were developed for each medication (i.e., SIAM(TACRO) and SIAM(SIRO) ) to assign weights to these clinically available adherence measures (self-report and trough levels) for the calculation of a non-adherence risk composite score. SIAM(TACRO) models included both self-report and tacrolimus trough levels and significantly predicted EM. For sirolimus, the model predictive of adherence as measured by EM consisted of the standard deviation of sirolimus trough levels only (SIAM(SIRO) ). Non-adherence risk can be effectively assessed using clinically available assessment tools. However, the best methods for using self-report and trough levels to predict non-adherence likely differ based on the medication for which adherence is being assessed.

Research paper thumbnail of Effects of Duration of Electronic Cigarette Use

Nicotine & Tobacco Research, 2014

This study examined the effect of duration electronic cigarette (e-cigarette) use on e-cigarette ... more This study examined the effect of duration electronic cigarette (e-cigarette) use on e-cigarette dependence, frequency of use, and strength of nicotine solution as well as number of cigarettes smoked per day. Individuals were recruited at e-cigarette retail locations in a large Midwestern metropolitan city of the United States in July 2013. A total of 159 participants completed a brief 29-item self-report measure that assessed behaviors and perceptions of use. The mean age of the participants was 35.8 years; 84.4% were White, and 53.7% were male. Increased duration of e-cigarette use was associated with fewer cigarettes smoked per day and differing patterns of dependence to e-cigarettes contingent upon smoking history. Additionally, increased duration of e-cigarette use was associated with increased frequency of use; however, this finding became nonsignificant when current tobacco cigarette use was accounted for, suggesting that individuals may increase e-cigarette use frequency as they decrease cigarette use. Overall, e-cigarette users tended to decrease the strength of nicotine in their e-cigarette products regardless of duration of use. Although preliminary in nature, this study identifies several factors that are important to consider when examining the effects of prolonged e-cigarette use. The implications of the current results should be informative to future studies that examine these variables in longitudinal designs.

Research paper thumbnail of Assessing Psychosocial Risk in Pediatric Inflammatory Bowel Disease

Journal of Pediatric Gastroenterology and Nutrition, 2014

Purpose: To present the preliminary psychometric properties of the Psychosocial Assessment Tool 2... more Purpose: To present the preliminary psychometric properties of the Psychosocial Assessment Tool 2.0_General (PAT2.0_GEN), a brief screener for psychosocial risk in families of children with Inflammatory Bowel Disease (IBD).

Research paper thumbnail of Which Nicotine Products Are Gateways to Regular Use?

American Journal of Preventive Medicine, 2015

Background: The potential for emerging tobacco products (ETPs) to be gateway products for further... more Background: The potential for emerging tobacco products (ETPs) to be gateway products for further tobacco use among youth is of significant concern.