James Murday | University of Southern California (original) (raw)

Papers by James Murday

Research paper thumbnail of Nanoscale Science and Engineering Education (NSEE)—The Next Steps

Journal of Nano Education, 2015

Identify and leverage insertion points that can be linked across grade levels for NSE concepts in... more Identify and leverage insertion points that can be linked across grade levels for NSE concepts in existing standards and curricula.  Create a central, searchable NSEE portal repository for teachers (possible models and/or partners included nanoHUB and the National Science Teachers Association). CC/TC  Create a best practices manual which builds on the efforts of the Nanotechnology Applications and Career Knowledge (NACK) Network, Nano-Link, and others to help with nationwide translation, replication, and tailoring of programs to specific local and regional needs. This manual should reflect the multitude and diversity of approaches. Undergraduate  Create and promote interdisciplinary cooperation and professional development opportunities among educators.  Promote the interdisciplinary nature and societal impacts of NSE in order to increase diversity in the student population. Graduate  Address the pipeline for students entering graduate education with special attention to building and maintaining trusted relationships with institutions which traditionally serve underrepresented groups in order to encourage underrepresented populations in STEM and NSE. Continuing  Identify the resources already available, for example from the ATE Centers or courses on nanoHUB, and make it easy for anyone to assemble these into learning packages tailored to specific curricula need. Informal  Refocus NSE outreach efforts around specific applications that address societal Grand Challenges in order to increase relevance and interest for the public.  Expand the reach of the Nanoscale Informal Science Education (NISE) Network beyond museums and research centers to youth-serving, community based national organizations that reach a broad demographic including underserved and underrepresented audiences. Consideration of all the recommendations leads to a number of key findings that cut across the stages (the following list is not prioritized):  Identify, develop, and evolve the NSEE workforce skillset requirements (and the education stages necessary to acquire those skills).  Review the existing NSEE efforts to identify and disseminate best practices. (As a start, the existing web accessible K-12 teaching aides have been collated in Appendix D.)  Identify, evolve, and/or develop NSEE materials with well-defined links to appropriate standards and curricula. Additionally, promote that material scale-up and widespread use of those materials.  Establish a central, searchable, e-portal that identifies and provides links to vetted NSEE materials, is readily accessible, designed for intuitive use, and sustainable.  Develop a national network of regional education hubs that effectively utilize the diverse stakeholder communities, leverage national forums, and address the challenges identified in the other recommendations.  Establish clearly defined, nanotechnology-enabled approaches toward the solution of societal Grand Challenges in order to engage students, underrepresented populations, and general public interest. The Commonwealth of Virginia and the state of Colorado recently incorporated nanotechnology into their new K-12 Science Standards of Learning. As they work to implement those standards, there is an immediate opportunity for the NSEE community to assist. The National Nanotechnology Coordination Office (NNCO) has an interest and charter in promulgating NSEE at a national scale. Workshop funds were used to procure selected teaching aides that were displayed at the workshop exhibition. The NNCO will use those materials in its national level NSEE efforts.

Research paper thumbnail of Review of surface physics

Naval Research Lab. Report, 1975

Objectives:IL17 is a critical pro-in ammatory cytokine that is involved in in ammation, multidrug... more Objectives:IL17 is a critical pro-in ammatory cytokine that is involved in in ammation, multidrug resistance and growth persistence pathways in cancer. This study is aiming at studying the expression of IL17 and hormonal receptors expressionin benign and malignant breast lesions using immunohistochemical staining methods. Results:A total of 137 cases of breast lesions were studied,97 (70.8%) were malignant and 40 (29.2%) were benign cases. Age range for malignant and benign cases were between 26 to 80 years [mean age 50±2 years], and 20 to 70 years[mean age 41±4 years], respectively, Odds ratio= 2.3 [1.78-1.99, 95% CI].The majority of the histopathological diagnosis of the benign and malignant lesions were 21 (15.3%) bro-adenomas and 87 (63.5%) invasive ductal carcinoma, respectively. Expression of IL17 and age were insigni cantly negatively correlated for both groups; benign cases [r=-0.054, P value 0.742] and malignant cases [r=-0.080, P value 0.444]. IL17 expression was showing insigni cant association with age group, P value 0.065. IL17 expression showed a statistical signi cance based on the different histopathological diagnosis, P value 0.035. Expression levels of estrogen, progesterone, and human epidermal receptors were showing insigni cant difference among IL17 expression categories, P values 0.678, 0.623, and 0.361, respectively. Introduction: Breast cancer (BC) is one of the global prevalent malignancies among females [1]. According to 2019 cancer statistics, the incidence of BC is surprisingly increasing compared to earlier reports in 2018. Not surprisingly, the rate of mortality is very high in the African developing countries owing to socioeconomic factors [2]. Importantly, the majority of women in these countries were diagnosed at late stages of the disease that ominously, has been metastasized [2]. in a previous study, among 120 patients diagnosed with benign lesion and were followed up for almost 20 years, 34% of all palpable lesions were found to be malignant tumors followed by bro-adenoma (28%), brocystic diseases (11%), in ammatory changes (11%), and other phylloid tumors and lactation changes (6%) [3]. According to the WHO there are several features in present in the benign lesions that are well known as pre-cancerous signs [4]. Metastasis and drug resistance constitute important problems in BC management and survival as well [5]. Lately, a number of studies have addressed the role of several mediators in determining the underlying mechanisms of BC invasion and persistence. These studies investigated the role of cytokines expression among both benign and malignant cancer patients, their nding was quite unique to further investigate the role of cytokines expression not only to understand the invasion mechanism, but also as diagnostic and prognostic markers for cancer development [6, 7]. Recently, cytokines and other ligands of immune system have been reported as instrumental factors in tumor microenvironment, and many of them are considered as prognostic and therapeutic targets in cancer [8, 9]. Basically, Interleukin-17 (IL17) is one of these important mediators which have strong

Research paper thumbnail of The structure and infrastructure of the global nanotechnology literature

Journal of Nanoparticle Research, 2006

Text mining is the extraction of useful information from large volumes of text. A text mining ana... more Text mining is the extraction of useful information from large volumes of text. A text mining analysis of the global open nanotechnology literature was performed. Records from the Science Citation Index (SCI)/Social SCI were analyzed to provide the infrastructure of the global nanotechnology literature (prolific authors/journals/institutions/countries, most cited authors/papers/journals) and the thematic structure (taxonomy) of the global nanotechnology literature, from

Research paper thumbnail of Analytical approach to ball‐bearing surface chemistry

Journal of Vacuum Science and …, 1977

Page 1. Analytical approach to ball-bearing surface chemistry* Elaine G. Shafrin and James S. Mur... more Page 1. Analytical approach to ball-bearing surface chemistry* Elaine G. Shafrin and James S. Murday Naval Research Laboratory, Washington, D. С 20375 (Received 30 August 1976; in final form 18 October 1976) The surface ...

Research paper thumbnail of Nanoscale Science and Engineering Education (NSEE)—The Next Steps

Journal of Nano Education, 2015

Identify and leverage insertion points that can be linked across grade levels for NSE concepts in... more Identify and leverage insertion points that can be linked across grade levels for NSE concepts in existing standards and curricula.  Create a central, searchable NSEE portal repository for teachers (possible models and/or partners included nanoHUB and the National Science Teachers Association). CC/TC  Create a best practices manual which builds on the efforts of the Nanotechnology Applications and Career Knowledge (NACK) Network, Nano-Link, and others to help with nationwide translation, replication, and tailoring of programs to specific local and regional needs. This manual should reflect the multitude and diversity of approaches. Undergraduate  Create and promote interdisciplinary cooperation and professional development opportunities among educators.  Promote the interdisciplinary nature and societal impacts of NSE in order to increase diversity in the student population. Graduate  Address the pipeline for students entering graduate education with special attention to building and maintaining trusted relationships with institutions which traditionally serve underrepresented groups in order to encourage underrepresented populations in STEM and NSE. Continuing  Identify the resources already available, for example from the ATE Centers or courses on nanoHUB, and make it easy for anyone to assemble these into learning packages tailored to specific curricula need. Informal  Refocus NSE outreach efforts around specific applications that address societal Grand Challenges in order to increase relevance and interest for the public.  Expand the reach of the Nanoscale Informal Science Education (NISE) Network beyond museums and research centers to youth-serving, community based national organizations that reach a broad demographic including underserved and underrepresented audiences. Consideration of all the recommendations leads to a number of key findings that cut across the stages (the following list is not prioritized):  Identify, develop, and evolve the NSEE workforce skillset requirements (and the education stages necessary to acquire those skills).  Review the existing NSEE efforts to identify and disseminate best practices. (As a start, the existing web accessible K-12 teaching aides have been collated in Appendix D.)  Identify, evolve, and/or develop NSEE materials with well-defined links to appropriate standards and curricula. Additionally, promote that material scale-up and widespread use of those materials.  Establish a central, searchable, e-portal that identifies and provides links to vetted NSEE materials, is readily accessible, designed for intuitive use, and sustainable.  Develop a national network of regional education hubs that effectively utilize the diverse stakeholder communities, leverage national forums, and address the challenges identified in the other recommendations.  Establish clearly defined, nanotechnology-enabled approaches toward the solution of societal Grand Challenges in order to engage students, underrepresented populations, and general public interest. The Commonwealth of Virginia and the state of Colorado recently incorporated nanotechnology into their new K-12 Science Standards of Learning. As they work to implement those standards, there is an immediate opportunity for the NSEE community to assist. The National Nanotechnology Coordination Office (NNCO) has an interest and charter in promulgating NSEE at a national scale. Workshop funds were used to procure selected teaching aides that were displayed at the workshop exhibition. The NNCO will use those materials in its national level NSEE efforts.

Research paper thumbnail of Review of surface physics

Naval Research Lab. Report, 1975

Objectives:IL17 is a critical pro-in ammatory cytokine that is involved in in ammation, multidrug... more Objectives:IL17 is a critical pro-in ammatory cytokine that is involved in in ammation, multidrug resistance and growth persistence pathways in cancer. This study is aiming at studying the expression of IL17 and hormonal receptors expressionin benign and malignant breast lesions using immunohistochemical staining methods. Results:A total of 137 cases of breast lesions were studied,97 (70.8%) were malignant and 40 (29.2%) were benign cases. Age range for malignant and benign cases were between 26 to 80 years [mean age 50±2 years], and 20 to 70 years[mean age 41±4 years], respectively, Odds ratio= 2.3 [1.78-1.99, 95% CI].The majority of the histopathological diagnosis of the benign and malignant lesions were 21 (15.3%) bro-adenomas and 87 (63.5%) invasive ductal carcinoma, respectively. Expression of IL17 and age were insigni cantly negatively correlated for both groups; benign cases [r=-0.054, P value 0.742] and malignant cases [r=-0.080, P value 0.444]. IL17 expression was showing insigni cant association with age group, P value 0.065. IL17 expression showed a statistical signi cance based on the different histopathological diagnosis, P value 0.035. Expression levels of estrogen, progesterone, and human epidermal receptors were showing insigni cant difference among IL17 expression categories, P values 0.678, 0.623, and 0.361, respectively. Introduction: Breast cancer (BC) is one of the global prevalent malignancies among females [1]. According to 2019 cancer statistics, the incidence of BC is surprisingly increasing compared to earlier reports in 2018. Not surprisingly, the rate of mortality is very high in the African developing countries owing to socioeconomic factors [2]. Importantly, the majority of women in these countries were diagnosed at late stages of the disease that ominously, has been metastasized [2]. in a previous study, among 120 patients diagnosed with benign lesion and were followed up for almost 20 years, 34% of all palpable lesions were found to be malignant tumors followed by bro-adenoma (28%), brocystic diseases (11%), in ammatory changes (11%), and other phylloid tumors and lactation changes (6%) [3]. According to the WHO there are several features in present in the benign lesions that are well known as pre-cancerous signs [4]. Metastasis and drug resistance constitute important problems in BC management and survival as well [5]. Lately, a number of studies have addressed the role of several mediators in determining the underlying mechanisms of BC invasion and persistence. These studies investigated the role of cytokines expression among both benign and malignant cancer patients, their nding was quite unique to further investigate the role of cytokines expression not only to understand the invasion mechanism, but also as diagnostic and prognostic markers for cancer development [6, 7]. Recently, cytokines and other ligands of immune system have been reported as instrumental factors in tumor microenvironment, and many of them are considered as prognostic and therapeutic targets in cancer [8, 9]. Basically, Interleukin-17 (IL17) is one of these important mediators which have strong

Research paper thumbnail of The structure and infrastructure of the global nanotechnology literature

Journal of Nanoparticle Research, 2006

Text mining is the extraction of useful information from large volumes of text. A text mining ana... more Text mining is the extraction of useful information from large volumes of text. A text mining analysis of the global open nanotechnology literature was performed. Records from the Science Citation Index (SCI)/Social SCI were analyzed to provide the infrastructure of the global nanotechnology literature (prolific authors/journals/institutions/countries, most cited authors/papers/journals) and the thematic structure (taxonomy) of the global nanotechnology literature, from

Research paper thumbnail of Analytical approach to ball‐bearing surface chemistry

Journal of Vacuum Science and …, 1977

Page 1. Analytical approach to ball-bearing surface chemistry* Elaine G. Shafrin and James S. Mur... more Page 1. Analytical approach to ball-bearing surface chemistry* Elaine G. Shafrin and James S. Murday Naval Research Laboratory, Washington, D. С 20375 (Received 30 August 1976; in final form 18 October 1976) The surface ...