Ladislav Volicer | University of South Florida (original) (raw)
Uploads
Papers by Ladislav Volicer
Neurobiology of Aging, 2000
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2005
Normal sleep-wake regulation is dependent upon an oscillatory circadian rhythm promoting alertnes... more Normal sleep-wake regulation is dependent upon an oscillatory circadian rhythm promoting alertness and sleep at appropriate times of day. Circadian rhythms have been noted to be disturbed as a consequence of both normal aging and age-associated pathologies like Alzheimer disease (AD). However, the relationship between the consequences of normal versus pathological aging upon circadian regulation remains unclear. The authors evaluated the similarities and differences between the consequences of aging and AD on endogenous circadian rhythm. Authors measured locomotor activity and, with a constant routine protocol, core body temperature, examining differences and similarities in circadian disturbances in groups of normal elderly and patients with probable AD (pAD), as compared with a comparison group of young, normal volunteers, measuring endogenous circadian amplitude (ECA) and endogenous circadian phase (ECP) of core body temperature, and made parametric and nonparametric assessments ...
Experimental Neurology, 1995
Pick disease is a rare progressive dementing illness characterized by severe atrophy of the front... more Pick disease is a rare progressive dementing illness characterized by severe atrophy of the frontal and temporal lobes. Clinically, Pick disease may be difficult to distinguish from Alzheimer disease (AD). The fact that Pick disease is often familial, and the evidence ...
Alzheimer's & Dementia, 2007
International Journal of Environmental Research and Public Health
An investigation of inappropriate medication use in treatment of depressivity in institutionalize... more An investigation of inappropriate medication use in treatment of depressivity in institutionalized older adults, based on a nurse-led evaluation of functional status and depressive symptoms in nursing home residents. Methods: A cross-sectional multicenter study was performed using records from 1087 residents cared for in fifteen nursing homes (NHs) in the Czech Republic. Inclusion criteria were being a permanent resident of one of the facilities, being 60 years of age or older, having a Geriatric Depression Scale score of 6 or more, and having a Mini Mental State examination score 10 or more. The final sample for analysis included 317 depressed NH residents. Results: 52 percent of NH residents with depressivity had no antidepressant treatment. Benzodiazepines were the only medication in 16 percent of depressed residents, and were added to antidepressant treatment in 18 percent of residents. Benzodiazepine users had significantly higher GDS scores compared to non-users (p = 0.007). C...
Geriatrics, 2021
Palliative care including hospice care is appropriate for advanced dementia, but policy initiativ... more Palliative care including hospice care is appropriate for advanced dementia, but policy initiatives and implementation have lagged, while treatment may vary. We compare care for people with advanced dementia in the United States (US), The Netherlands, and Israel. We conducted a narrative literature review and expert physician consultation around a case scenario focusing on three domains in the care of people with advanced dementia: (1) place of residence, (2) access to palliative care, and (3) treatment. We found that most people with advanced dementia live in nursing homes in the US and The Netherlands, and in the community in Israel. Access to specialist palliative and hospice care is improving in the US but is limited in The Netherlands and Israel. The two data sources consistently showed that treatment varies considerably between countries with, for example, artificial nutrition and hydration differing by state in the US, strongly discouraged in The Netherlands, and widely used ...
Geriatric Medicine and Care, 2018
Geriatric Medicine and Care, 2018
Journal of the American Medical Directors Association, 2020
MOJ Gerontology & Geriatrics, 2017
Journal of the American Medical Directors Association, 2020
MOJ Gerontology & Geriatrics, 2017
European Geriatric Medicine, 2011
BackgroundDepression in nursing home residents decreases their quality of life and is related to ... more BackgroundDepression in nursing home residents decreases their quality of life and is related to behavioral symptoms of dementia. Diagnosing depression in patients with advanced cognitive impairment may be challenging. The purpose of this study was to find out how well depression is diagnosed and treated in Dutch nursing homes in relation with age and dementia severity.
European Geriatric Medicine, 2011
BackgroundDepression in nursing home residents decreases their quality of life and is related to ... more BackgroundDepression in nursing home residents decreases their quality of life and is related to behavioral symptoms of dementia. Diagnosing depression in patients with advanced cognitive impairment may be challenging. The purpose of this study was to find out how well depression is diagnosed and treated in Dutch nursing homes in relation with age and dementia severity.
Archives of Neuroscience, 2016
Journal of Aging Science, 2016
Journal of Aging Science, 2015
International Psychogeriatrics, 2015
ABSTRACTBackground:People with dementia may benefit from palliative care which specifically addre... more ABSTRACTBackground:People with dementia may benefit from palliative care which specifically addresses the needs of patients and families affected by this life-limiting disease. On behalf of the European Association for Palliative Care (EAPC), we recently performed a Delphi study to define domains for palliative care in dementia and to provide recommendations for optimal care. An international panel of experts in palliative care, dementia care or both, achieved consensus on almost all domains and recommendations, but the domain concerning the applicability of palliative care to dementia required revision.Methods:To examine in detail, the opinions of the international panel of 64 experts around the applicability of palliative care, we explored feedback they provided in the Delphi process. To examine which experts found it less important or less applicable, ordinal regression analyses related characteristics of the panelists to ratings of overall importance of the applicability domain,...
Neurobiology of Aging, 2000
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2005
Normal sleep-wake regulation is dependent upon an oscillatory circadian rhythm promoting alertnes... more Normal sleep-wake regulation is dependent upon an oscillatory circadian rhythm promoting alertness and sleep at appropriate times of day. Circadian rhythms have been noted to be disturbed as a consequence of both normal aging and age-associated pathologies like Alzheimer disease (AD). However, the relationship between the consequences of normal versus pathological aging upon circadian regulation remains unclear. The authors evaluated the similarities and differences between the consequences of aging and AD on endogenous circadian rhythm. Authors measured locomotor activity and, with a constant routine protocol, core body temperature, examining differences and similarities in circadian disturbances in groups of normal elderly and patients with probable AD (pAD), as compared with a comparison group of young, normal volunteers, measuring endogenous circadian amplitude (ECA) and endogenous circadian phase (ECP) of core body temperature, and made parametric and nonparametric assessments ...
Experimental Neurology, 1995
Pick disease is a rare progressive dementing illness characterized by severe atrophy of the front... more Pick disease is a rare progressive dementing illness characterized by severe atrophy of the frontal and temporal lobes. Clinically, Pick disease may be difficult to distinguish from Alzheimer disease (AD). The fact that Pick disease is often familial, and the evidence ...
Alzheimer's & Dementia, 2007
International Journal of Environmental Research and Public Health
An investigation of inappropriate medication use in treatment of depressivity in institutionalize... more An investigation of inappropriate medication use in treatment of depressivity in institutionalized older adults, based on a nurse-led evaluation of functional status and depressive symptoms in nursing home residents. Methods: A cross-sectional multicenter study was performed using records from 1087 residents cared for in fifteen nursing homes (NHs) in the Czech Republic. Inclusion criteria were being a permanent resident of one of the facilities, being 60 years of age or older, having a Geriatric Depression Scale score of 6 or more, and having a Mini Mental State examination score 10 or more. The final sample for analysis included 317 depressed NH residents. Results: 52 percent of NH residents with depressivity had no antidepressant treatment. Benzodiazepines were the only medication in 16 percent of depressed residents, and were added to antidepressant treatment in 18 percent of residents. Benzodiazepine users had significantly higher GDS scores compared to non-users (p = 0.007). C...
Geriatrics, 2021
Palliative care including hospice care is appropriate for advanced dementia, but policy initiativ... more Palliative care including hospice care is appropriate for advanced dementia, but policy initiatives and implementation have lagged, while treatment may vary. We compare care for people with advanced dementia in the United States (US), The Netherlands, and Israel. We conducted a narrative literature review and expert physician consultation around a case scenario focusing on three domains in the care of people with advanced dementia: (1) place of residence, (2) access to palliative care, and (3) treatment. We found that most people with advanced dementia live in nursing homes in the US and The Netherlands, and in the community in Israel. Access to specialist palliative and hospice care is improving in the US but is limited in The Netherlands and Israel. The two data sources consistently showed that treatment varies considerably between countries with, for example, artificial nutrition and hydration differing by state in the US, strongly discouraged in The Netherlands, and widely used ...
Geriatric Medicine and Care, 2018
Geriatric Medicine and Care, 2018
Journal of the American Medical Directors Association, 2020
MOJ Gerontology & Geriatrics, 2017
Journal of the American Medical Directors Association, 2020
MOJ Gerontology & Geriatrics, 2017
European Geriatric Medicine, 2011
BackgroundDepression in nursing home residents decreases their quality of life and is related to ... more BackgroundDepression in nursing home residents decreases their quality of life and is related to behavioral symptoms of dementia. Diagnosing depression in patients with advanced cognitive impairment may be challenging. The purpose of this study was to find out how well depression is diagnosed and treated in Dutch nursing homes in relation with age and dementia severity.
European Geriatric Medicine, 2011
BackgroundDepression in nursing home residents decreases their quality of life and is related to ... more BackgroundDepression in nursing home residents decreases their quality of life and is related to behavioral symptoms of dementia. Diagnosing depression in patients with advanced cognitive impairment may be challenging. The purpose of this study was to find out how well depression is diagnosed and treated in Dutch nursing homes in relation with age and dementia severity.
Archives of Neuroscience, 2016
Journal of Aging Science, 2016
Journal of Aging Science, 2015
International Psychogeriatrics, 2015
ABSTRACTBackground:People with dementia may benefit from palliative care which specifically addre... more ABSTRACTBackground:People with dementia may benefit from palliative care which specifically addresses the needs of patients and families affected by this life-limiting disease. On behalf of the European Association for Palliative Care (EAPC), we recently performed a Delphi study to define domains for palliative care in dementia and to provide recommendations for optimal care. An international panel of experts in palliative care, dementia care or both, achieved consensus on almost all domains and recommendations, but the domain concerning the applicability of palliative care to dementia required revision.Methods:To examine in detail, the opinions of the international panel of 64 experts around the applicability of palliative care, we explored feedback they provided in the Delphi process. To examine which experts found it less important or less applicable, ordinal regression analyses related characteristics of the panelists to ratings of overall importance of the applicability domain,...