MINAL BHADANE | The University of Toledo (original) (raw)
Papers by MINAL BHADANE
PM&R
Introduction: Reducing acute care readmissions from inpatient rehabilitation facilities (IRFs) is... more Introduction: Reducing acute care readmissions from inpatient rehabilitation facilities (IRFs) is a healthcare reform goal. Stroke patients have higher acute readmission rates & persistent impairments, warranting second IRF hospitalization consideration. Main Outcome Measure: Variables that increase the likelihood of a second IRF hospitalization.
Specialty section: This article was submitted to Stroke, a section of the journal
Optometry and Vision Science, 2020
SIGNIFICANCE: Visual demands today incorporate a significant amount of time using digital devices... more SIGNIFICANCE: Visual demands today incorporate a significant amount of time using digital devices. Results of this randomized crossover study of spherical and toric contact lenses demonstrated that participants were able to read smaller print size more comfortably and preferred toric contact lenses when using digital devices. PURPOSE: The purpose of this study was to assess how toric contact lens correction affects subjective and objective outcomes of astigmatic patients using real-world digital devices. METHODS: Adult participants, aged between 20 and 38 years with −0.75 to −1.50 D of astigmatism were enrolled in this double-masked randomized crossover 10-day study of Alcon Dailies Aqua Comfort Plus Sphere and Toric (Alcon, Geneva, Switzerland) contact lenses. Electronic high-and low-contrast near logMAR visual acuity and contrast sensitivity were tested. Reading performance was assessed using custom iPad applications; one used a reading sentences test, whereas the other analyzed zoom, contrast, and distance with website-based articles. Participants completed the Near Activity Visual Questionnaire and stated their preferred contact lens correction. RESULTS: Thirty seven participants were screened, 35 participants were enrolled, and 34 participants completed the study. Toric lens correction improved near high-and low-contrast visual acuity by 0.5 to 1 full line (P < .0001) and allowed participants to read one line smaller text on the iPad (P = .01). Participants increased the zoom 11% (P = .004) and the contrast 4% (P = .006) more with spherical lenses while reading articles. Participants held the iPad at approximately the same distance, about 33 cm (P = .63). Eighty five percent of participants preferred the toric correction (P < .0001). Participants reported improved satisfaction with toric lens correction (P = .0002) and noticed the most benefit with tasks such as reading small print and labels/instructions. CONCLUSIONS: This study used digital devices to demonstrate realistic benefits of toric contact lens designs for astigmatic patients.
BACKGROUND Minorities have an increased incidence of obesity-related cerebrovascular disease. Unf... more BACKGROUND Minorities have an increased incidence of obesity-related cerebrovascular disease. Unfortunately, effective weight management in this vulnerable population has significant barriers. OBJECTIVE Determine feasibility and preliminary treatment effects of using a SmartPhone based weight loss intervention versus food journals to monitor dietary patterns in minority acute stroke patients (Swipe out Stroke). METHODS Swipe out Stroke is a pilot Prospective Randomized Controlled Trial with Open Blinded Endpoint (PROBE) study. After written informed consent was obtained, both patients and their caregivers were screened for vascular risk factors using cluster enrollment at a Joint Commission Comprehensive Stroke Center in Houston Texas. Adaptive randomization was used for assignment to one of two groups – 1) behavior intervention with SmartPhone based self-monitoring, 2) behavior intervention with food journal self-monitoring. Caregivers joined the group of the study participant. The...
Journal of the National Medical Association, 2018
BACKGROUND AND PURPOSE: Women minorities have an overall increased lifetime incidence of cerebrov... more BACKGROUND AND PURPOSE: Women minorities have an overall increased lifetime incidence of cerebrovascular disease. The provision of risk factor modification in this group can prove difficult. In a population-based study, we used cluster enrollment to identify vascular risk factors in the female caregivers of stroke survivor study participants. METHODS: Obese women caregivers were identified as part of Swipe out Stroke, a Phase I PROBE study assessing the use of SmartPhone based intervention for dietary modification in minority stroke survivors. After written informed consent was obtained, both patients and caregivers were screened for vascular risk factors at study enrollment. Descriptive statistics were used to depict the study population. Continuous baseline variables were compared using 2 sample t-test or Wilcoxon rank-sum test by caregivers and patients. Categorical baseline variables were compared using Fisher's exact test. RESULTS: Thirty-six stroke patients (63.9% African-American, 36.1% Hispanic) and thirteen female caregivers (69.2% African-American, 30.8% Hispanic) were enrolled. Mean age, patients − 54.1 (SD 9.4), caregivers-51.3 (SD 15.6) years, education, employment status and family history of stroke or obesity did not differ significantly. Compared to stroke patients, female caregivers
Frontiers in neurology, 2017
Startling acoustic stimulation (SAS), via activation of reticulospinal (RS) pathways, has shown t... more Startling acoustic stimulation (SAS), via activation of reticulospinal (RS) pathways, has shown to increase muscle strength in healthy subjects. We hypothesized that, given RS hyperexcitability in stroke survivors, SAS could increase muscle strength in stroke survivors. The objective was to quantify the effect of SAS on maximal and sub-maximal voluntary elbow flexion on the contralesional (impaired) side in stroke survivors as compared to ipsilesional (non-impaired) side and healthy controls. Thirteen hemiparetic stroke survivors and 12 healthy subjects volunteered for this investigation. Acoustic stimulation was given at rest, during ballistic maximal and sustained sub-maximal isometric elbow contractions using low (80 dB) and high intensity sound (105 dB). The effect of acoustic stimuli was evaluated from EMG and force recordings. Prevalence of acoustic startle reflex with shorter latency in the impaired biceps was greater as compared to the response in the non-impaired side of st...
Scientific reports, Jun 28, 2016
The objective was to re-evaluate the controversial reports of EMG-torque relation between impaire... more The objective was to re-evaluate the controversial reports of EMG-torque relation between impaired and non-impaired sides using linear electrode array EMG recordings. Ten subjects with chronic stroke performed a series of submaximal isometric elbow flexion tasks. A 20-channel linear array was used to record surface EMG of the biceps brachii muscles from both impaired and non-impaired sides. M-wave recordings for bilateral biceps brachii muscles were also made. Distribution of the slope of the EMG-torque relations for the individual channels showed a quasi-symmetrical "M" shaped pattern. The lowest value corresponded to the innervation zone (IZ) location. The highest value from the slope curve for each side was selected for comparison to minimize the effect of electrode placement and IZ asymmetry. The slope was greater on the impaired side in 4 of 10 subjects. There were a weak correlation between slope ratio and strength ratio and a moderate to high correlation between slo...
Frontiers in Neurology, 2015
Objective: To evaluate whether resting joint angle is indicative of severity of spasticity of the... more Objective: To evaluate whether resting joint angle is indicative of severity of spasticity of the elbow flexors in chronic stroke survivors. Methods: Seventeen hemiparetic stroke subjects (male: n = 13; female: n = 4; age: 37-89 years; 11 right and 6 left hemiplegia; averaged 54.8 months after stroke, ranging 12-107 months) participated in the study. The number of subjects with modified Ashworth scale score (MAS) = 0, 1, 1+, 2, and 3 was 3, 3, 5, 3, and 3, respectively. In a single experimental session, resting elbow joint angle, MAS, and Tardieu scale score (Tardieu R1) were measured. A customized motorized stretching device was used to stretch elbow flexors at 5, 50, and 100°/s, respectively. Biomechanical responses (peak reflex torque and reflex stiffness) of elbow flexors were quantified. Correlation analyses between clinical and biomechanical assessments were performed. Results: Resting elbow joint angle showed a strong positive correlation with Tardieu R1 (r = 0.77, p < 0.01) and a very strong negative correlation with MAS (r = −0.89, p < 0.01). The resting angle also had strong correlations with biomechanical measures (r = −0.63 to −0.76, p < 0.01). Conclusion: Our study provides experimental evidence for anecdotal observation that the resting elbow joint angle correlates with severity of spasticity in chronic stroke. Resting angle observation for spasticity assessment can and will be an easy, yet a valid way of spasticity estimation in clinical settings, particularly for small muscles or muscles which are not easily measurable by common clinical methods.
Clinical Neurophysiology, 2014
Objective-To use evoked (M-wave) and voluntary (during maximal voluntary contraction (MVC)) EMG r... more Objective-To use evoked (M-wave) and voluntary (during maximal voluntary contraction (MVC)) EMG recordings to estimate the voluntary activation level in chronic stroke. Methods-Nine chronic hemiparetic stroke subjects participated in the experiment. M-wave (EMG M-wave) and MVC (EMG MVC) EMG values of the biceps brachii muscles were recorded. Results-Peak torque was significantly smaller on the impaired than non-impaired side. EMG M-wave was also significantly smaller on the impaired than non-impaired side. However, the normalized EMG M-wave /Torque MVC ratio was not significantly different between two sides. In contrast, both absolute EMG MVC and normalized EMG MVC /Torque MVC were smaller on the impaired than non-impaired side. The voluntary activation level, EMG MVC/M-wave , was also smaller on the impaired than non-impaired side. The voluntary activation level on the impaired side was highly correlated with weakness (R=0.72), but very low (R=0.32) on the non-impaired side. Conclusion-Collectively, our findings suggest that both peripheral and central factors contribute to post-stroke weakness, but activation deficit correlates most closely with weakness as estimated from maximum voluntary torque generation.
ABSTRACT: This paper presents a control of stiffness for an actuator that utilizes the properties... more ABSTRACT: This paper presents a control of stiffness for an actuator that utilizes the properties of shape memory alloy (SMA) wires. The control algorithm is developed based on angular position of the SMA actuated arm. The model for calculation of stiffness is prepared in MATLAB/Simulink environment. In this application, a PID controller is designed to regulate the applied voltage of the SMA wire. For all the experiments, dSPACE hardware-in-the-loop solution is used. Simulation and experimental results are collected to validate system model. Result show good performance and control of stiffness through PID control system. INTRODUCTION:
PM&R
Introduction: Reducing acute care readmissions from inpatient rehabilitation facilities (IRFs) is... more Introduction: Reducing acute care readmissions from inpatient rehabilitation facilities (IRFs) is a healthcare reform goal. Stroke patients have higher acute readmission rates & persistent impairments, warranting second IRF hospitalization consideration. Main Outcome Measure: Variables that increase the likelihood of a second IRF hospitalization.
Specialty section: This article was submitted to Stroke, a section of the journal
Optometry and Vision Science, 2020
SIGNIFICANCE: Visual demands today incorporate a significant amount of time using digital devices... more SIGNIFICANCE: Visual demands today incorporate a significant amount of time using digital devices. Results of this randomized crossover study of spherical and toric contact lenses demonstrated that participants were able to read smaller print size more comfortably and preferred toric contact lenses when using digital devices. PURPOSE: The purpose of this study was to assess how toric contact lens correction affects subjective and objective outcomes of astigmatic patients using real-world digital devices. METHODS: Adult participants, aged between 20 and 38 years with −0.75 to −1.50 D of astigmatism were enrolled in this double-masked randomized crossover 10-day study of Alcon Dailies Aqua Comfort Plus Sphere and Toric (Alcon, Geneva, Switzerland) contact lenses. Electronic high-and low-contrast near logMAR visual acuity and contrast sensitivity were tested. Reading performance was assessed using custom iPad applications; one used a reading sentences test, whereas the other analyzed zoom, contrast, and distance with website-based articles. Participants completed the Near Activity Visual Questionnaire and stated their preferred contact lens correction. RESULTS: Thirty seven participants were screened, 35 participants were enrolled, and 34 participants completed the study. Toric lens correction improved near high-and low-contrast visual acuity by 0.5 to 1 full line (P < .0001) and allowed participants to read one line smaller text on the iPad (P = .01). Participants increased the zoom 11% (P = .004) and the contrast 4% (P = .006) more with spherical lenses while reading articles. Participants held the iPad at approximately the same distance, about 33 cm (P = .63). Eighty five percent of participants preferred the toric correction (P < .0001). Participants reported improved satisfaction with toric lens correction (P = .0002) and noticed the most benefit with tasks such as reading small print and labels/instructions. CONCLUSIONS: This study used digital devices to demonstrate realistic benefits of toric contact lens designs for astigmatic patients.
BACKGROUND Minorities have an increased incidence of obesity-related cerebrovascular disease. Unf... more BACKGROUND Minorities have an increased incidence of obesity-related cerebrovascular disease. Unfortunately, effective weight management in this vulnerable population has significant barriers. OBJECTIVE Determine feasibility and preliminary treatment effects of using a SmartPhone based weight loss intervention versus food journals to monitor dietary patterns in minority acute stroke patients (Swipe out Stroke). METHODS Swipe out Stroke is a pilot Prospective Randomized Controlled Trial with Open Blinded Endpoint (PROBE) study. After written informed consent was obtained, both patients and their caregivers were screened for vascular risk factors using cluster enrollment at a Joint Commission Comprehensive Stroke Center in Houston Texas. Adaptive randomization was used for assignment to one of two groups – 1) behavior intervention with SmartPhone based self-monitoring, 2) behavior intervention with food journal self-monitoring. Caregivers joined the group of the study participant. The...
Journal of the National Medical Association, 2018
BACKGROUND AND PURPOSE: Women minorities have an overall increased lifetime incidence of cerebrov... more BACKGROUND AND PURPOSE: Women minorities have an overall increased lifetime incidence of cerebrovascular disease. The provision of risk factor modification in this group can prove difficult. In a population-based study, we used cluster enrollment to identify vascular risk factors in the female caregivers of stroke survivor study participants. METHODS: Obese women caregivers were identified as part of Swipe out Stroke, a Phase I PROBE study assessing the use of SmartPhone based intervention for dietary modification in minority stroke survivors. After written informed consent was obtained, both patients and caregivers were screened for vascular risk factors at study enrollment. Descriptive statistics were used to depict the study population. Continuous baseline variables were compared using 2 sample t-test or Wilcoxon rank-sum test by caregivers and patients. Categorical baseline variables were compared using Fisher's exact test. RESULTS: Thirty-six stroke patients (63.9% African-American, 36.1% Hispanic) and thirteen female caregivers (69.2% African-American, 30.8% Hispanic) were enrolled. Mean age, patients − 54.1 (SD 9.4), caregivers-51.3 (SD 15.6) years, education, employment status and family history of stroke or obesity did not differ significantly. Compared to stroke patients, female caregivers
Frontiers in neurology, 2017
Startling acoustic stimulation (SAS), via activation of reticulospinal (RS) pathways, has shown t... more Startling acoustic stimulation (SAS), via activation of reticulospinal (RS) pathways, has shown to increase muscle strength in healthy subjects. We hypothesized that, given RS hyperexcitability in stroke survivors, SAS could increase muscle strength in stroke survivors. The objective was to quantify the effect of SAS on maximal and sub-maximal voluntary elbow flexion on the contralesional (impaired) side in stroke survivors as compared to ipsilesional (non-impaired) side and healthy controls. Thirteen hemiparetic stroke survivors and 12 healthy subjects volunteered for this investigation. Acoustic stimulation was given at rest, during ballistic maximal and sustained sub-maximal isometric elbow contractions using low (80 dB) and high intensity sound (105 dB). The effect of acoustic stimuli was evaluated from EMG and force recordings. Prevalence of acoustic startle reflex with shorter latency in the impaired biceps was greater as compared to the response in the non-impaired side of st...
Scientific reports, Jun 28, 2016
The objective was to re-evaluate the controversial reports of EMG-torque relation between impaire... more The objective was to re-evaluate the controversial reports of EMG-torque relation between impaired and non-impaired sides using linear electrode array EMG recordings. Ten subjects with chronic stroke performed a series of submaximal isometric elbow flexion tasks. A 20-channel linear array was used to record surface EMG of the biceps brachii muscles from both impaired and non-impaired sides. M-wave recordings for bilateral biceps brachii muscles were also made. Distribution of the slope of the EMG-torque relations for the individual channels showed a quasi-symmetrical "M" shaped pattern. The lowest value corresponded to the innervation zone (IZ) location. The highest value from the slope curve for each side was selected for comparison to minimize the effect of electrode placement and IZ asymmetry. The slope was greater on the impaired side in 4 of 10 subjects. There were a weak correlation between slope ratio and strength ratio and a moderate to high correlation between slo...
Frontiers in Neurology, 2015
Objective: To evaluate whether resting joint angle is indicative of severity of spasticity of the... more Objective: To evaluate whether resting joint angle is indicative of severity of spasticity of the elbow flexors in chronic stroke survivors. Methods: Seventeen hemiparetic stroke subjects (male: n = 13; female: n = 4; age: 37-89 years; 11 right and 6 left hemiplegia; averaged 54.8 months after stroke, ranging 12-107 months) participated in the study. The number of subjects with modified Ashworth scale score (MAS) = 0, 1, 1+, 2, and 3 was 3, 3, 5, 3, and 3, respectively. In a single experimental session, resting elbow joint angle, MAS, and Tardieu scale score (Tardieu R1) were measured. A customized motorized stretching device was used to stretch elbow flexors at 5, 50, and 100°/s, respectively. Biomechanical responses (peak reflex torque and reflex stiffness) of elbow flexors were quantified. Correlation analyses between clinical and biomechanical assessments were performed. Results: Resting elbow joint angle showed a strong positive correlation with Tardieu R1 (r = 0.77, p < 0.01) and a very strong negative correlation with MAS (r = −0.89, p < 0.01). The resting angle also had strong correlations with biomechanical measures (r = −0.63 to −0.76, p < 0.01). Conclusion: Our study provides experimental evidence for anecdotal observation that the resting elbow joint angle correlates with severity of spasticity in chronic stroke. Resting angle observation for spasticity assessment can and will be an easy, yet a valid way of spasticity estimation in clinical settings, particularly for small muscles or muscles which are not easily measurable by common clinical methods.
Clinical Neurophysiology, 2014
Objective-To use evoked (M-wave) and voluntary (during maximal voluntary contraction (MVC)) EMG r... more Objective-To use evoked (M-wave) and voluntary (during maximal voluntary contraction (MVC)) EMG recordings to estimate the voluntary activation level in chronic stroke. Methods-Nine chronic hemiparetic stroke subjects participated in the experiment. M-wave (EMG M-wave) and MVC (EMG MVC) EMG values of the biceps brachii muscles were recorded. Results-Peak torque was significantly smaller on the impaired than non-impaired side. EMG M-wave was also significantly smaller on the impaired than non-impaired side. However, the normalized EMG M-wave /Torque MVC ratio was not significantly different between two sides. In contrast, both absolute EMG MVC and normalized EMG MVC /Torque MVC were smaller on the impaired than non-impaired side. The voluntary activation level, EMG MVC/M-wave , was also smaller on the impaired than non-impaired side. The voluntary activation level on the impaired side was highly correlated with weakness (R=0.72), but very low (R=0.32) on the non-impaired side. Conclusion-Collectively, our findings suggest that both peripheral and central factors contribute to post-stroke weakness, but activation deficit correlates most closely with weakness as estimated from maximum voluntary torque generation.
ABSTRACT: This paper presents a control of stiffness for an actuator that utilizes the properties... more ABSTRACT: This paper presents a control of stiffness for an actuator that utilizes the properties of shape memory alloy (SMA) wires. The control algorithm is developed based on angular position of the SMA actuated arm. The model for calculation of stiffness is prepared in MATLAB/Simulink environment. In this application, a PID controller is designed to regulate the applied voltage of the SMA wire. For all the experiments, dSPACE hardware-in-the-loop solution is used. Simulation and experimental results are collected to validate system model. Result show good performance and control of stiffness through PID control system. INTRODUCTION: