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Research paper thumbnail of Evaluation of an artificial intelligence coronary artery calcium scoring model from computed tomography

European Radiology

Objectives Coronary artery calcium (CAC) scores derived from computed tomography (CT) scans are u... more Objectives Coronary artery calcium (CAC) scores derived from computed tomography (CT) scans are used for cardiovascular risk stratification. Artificial intelligence (AI) can assist in CAC quantification and potentially reduce the time required for human analysis. This study aimed to develop and evaluate a fully automated model that identifies and quantifies CAC. Methods Fully convolutional neural networks for automated CAC scoring were developed and trained on 2439 cardiac CT scans and validated using 771 scans. The model was tested on an independent set of 1849 cardiac CT scans. Agatston CAC scores were further categorised into five risk categories (0, 1–10, 11–100, 101–400, and > 400). Automated scores were compared to the manual reference standard (level 3 expert readers). Results Of 1849 scans used for model testing (mean age 55.7 ± 10.5 years, 49% males), the automated model detected the presence of CAC in 867 (47%) scans compared with 815 (44%) by human readers (p = 0.09). ...

Research paper thumbnail of Multi-disciplinary treatment of retroperitoneal lymphatic malformations

Journal of Pediatric Surgery Case Reports, 2020

Research paper thumbnail of Management of adnexal torsion in the paediatric adolescent population at Western Australia's single tertiary children's hospital over the last 10 years: Retrospective study

Journal of Minimally Invasive Gynecology, 2020

OBJECTIVE To review our institutional data regarding the management of adnexal torsion (AT) and a... more OBJECTIVE To review our institutional data regarding the management of adnexal torsion (AT) and assess the ovarian conservation rates. DESIGN Retrospective study SETTING: Tertiary Children's Hospital PATIENTS: Paediatric and adolescent patients with surgically diagnosed AT. Participants (n=54, mean age 9.80 ± 3.95 years) were identified between June 2010 to May 2019. INTERVENTIONS Surgical management of adnexal AT. MEASUREMENTS The primary outcome was to determine the ovarian conservation rates in AT cases. The secondary outcomes were to determine the incidence of AT to total Emergency Department (ED) presentations, decision to operation theatre (OT) time in AT cases, return to OT, histopathology and follow-up with ultrasound to determine ovarian function. Data were collected on demographic and clinical characteristics. Continuous data were compared with t- or Kruskal-Wallis tests; categorical data were compared with Chi-Square test. MAIN RESULTS 52 patients (96.3%) had ovarian conservation. 53 (98%) had laparoscopic management. Incidence rate for AT cases to total ED presentations for the last 10 years was 9.9/100,000 which were based on a Poisson distribution. Presentations to ED for AT cases have trended upwards since 2010. Decision to OT time was statistically significantly shorter in cases with preoperative suspicion of AT as compared to those with intraoperative diagnosis of AT (P=000). 7 (12.9%) returned to OT for suspicion of recurrent torsion. 5 (9.2%) of these had confirmed repeat AT. The presence of fever, pain duration, severity of pain and severity of torsion did not correlate with the follow up USS findings of ovarian activity. CONCLUSION The findings from our study suggests that high ovarian conservation rates are achievable in adnexal torsion cases. High index of suspicion is required to prevent delay in surgery.

Research paper thumbnail of Evaluation of an artificial intelligence coronary artery calcium scoring model from computed tomography

European Radiology

Objectives Coronary artery calcium (CAC) scores derived from computed tomography (CT) scans are u... more Objectives Coronary artery calcium (CAC) scores derived from computed tomography (CT) scans are used for cardiovascular risk stratification. Artificial intelligence (AI) can assist in CAC quantification and potentially reduce the time required for human analysis. This study aimed to develop and evaluate a fully automated model that identifies and quantifies CAC. Methods Fully convolutional neural networks for automated CAC scoring were developed and trained on 2439 cardiac CT scans and validated using 771 scans. The model was tested on an independent set of 1849 cardiac CT scans. Agatston CAC scores were further categorised into five risk categories (0, 1–10, 11–100, 101–400, and > 400). Automated scores were compared to the manual reference standard (level 3 expert readers). Results Of 1849 scans used for model testing (mean age 55.7 ± 10.5 years, 49% males), the automated model detected the presence of CAC in 867 (47%) scans compared with 815 (44%) by human readers (p = 0.09). ...

Research paper thumbnail of Multi-disciplinary treatment of retroperitoneal lymphatic malformations

Journal of Pediatric Surgery Case Reports, 2020

Research paper thumbnail of Management of adnexal torsion in the paediatric adolescent population at Western Australia's single tertiary children's hospital over the last 10 years: Retrospective study

Journal of Minimally Invasive Gynecology, 2020

OBJECTIVE To review our institutional data regarding the management of adnexal torsion (AT) and a... more OBJECTIVE To review our institutional data regarding the management of adnexal torsion (AT) and assess the ovarian conservation rates. DESIGN Retrospective study SETTING: Tertiary Children's Hospital PATIENTS: Paediatric and adolescent patients with surgically diagnosed AT. Participants (n=54, mean age 9.80 ± 3.95 years) were identified between June 2010 to May 2019. INTERVENTIONS Surgical management of adnexal AT. MEASUREMENTS The primary outcome was to determine the ovarian conservation rates in AT cases. The secondary outcomes were to determine the incidence of AT to total Emergency Department (ED) presentations, decision to operation theatre (OT) time in AT cases, return to OT, histopathology and follow-up with ultrasound to determine ovarian function. Data were collected on demographic and clinical characteristics. Continuous data were compared with t- or Kruskal-Wallis tests; categorical data were compared with Chi-Square test. MAIN RESULTS 52 patients (96.3%) had ovarian conservation. 53 (98%) had laparoscopic management. Incidence rate for AT cases to total ED presentations for the last 10 years was 9.9/100,000 which were based on a Poisson distribution. Presentations to ED for AT cases have trended upwards since 2010. Decision to OT time was statistically significantly shorter in cases with preoperative suspicion of AT as compared to those with intraoperative diagnosis of AT (P=000). 7 (12.9%) returned to OT for suspicion of recurrent torsion. 5 (9.2%) of these had confirmed repeat AT. The presence of fever, pain duration, severity of pain and severity of torsion did not correlate with the follow up USS findings of ovarian activity. CONCLUSION The findings from our study suggests that high ovarian conservation rates are achievable in adnexal torsion cases. High index of suspicion is required to prevent delay in surgery.

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