Anil Kumar H.S | Visvesvaraya Technological University (original) (raw)

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Papers by Anil Kumar H.S

Research paper thumbnail of alpha-galactosidase

α-D-Galactose-galactohydrolase (E.C.3.2.1.22), commonly referred to as α-galactosidase, catalyzes... more α-D-Galactose-galactohydrolase (E.C.3.2.1.22), commonly referred to as α-galactosidase, catalyzes the hydrolysis of α-galactosidic linkages in oligo-saccharide such as raffinose, melibiose, stachyose and verbaschose. Legumes and its derivatives represent nutritionally high quality food products whose major drawback is their high content of α-galacto-oligosaccharides. These are not digested in the small intestine due to the natural absence of α-galactosidase in mammals. Legume seeds were moistened and exposed to air for bacterial contamination through bating technique. In this work after alpha galactosidase producing bacteria were screened and isolated. α-galactosidase from different bacterial isolates was purified by ammonium sulphate precipitation of 45% and 65% saturation and further purified by gel filteration chromatography using Saphadex G-100. Optimization of temperature and pH was determined as 40 o C and 7.0 respectively. Effect of metallic ions on α-galactosidase was also investigated.

Research paper thumbnail of alpha-galactosidase

α-D-Galactose-galactohydrolase (E.C.3.2.1.22), commonly referred to as α-galactosidase, catalyzes... more α-D-Galactose-galactohydrolase (E.C.3.2.1.22), commonly referred to as α-galactosidase, catalyzes the hydrolysis of α-galactosidic linkages in oligo-saccharide such as raffinose, melibiose, stachyose and verbaschose. Legumes and its derivatives represent nutritionally high quality food products whose major drawback is their high content of α-galacto-oligosaccharides. These are not digested in the small intestine due to the natural absence of α-galactosidase in mammals. Legume seeds were moistened and exposed to air for bacterial contamination through bating technique. In this work after alpha galactosidase producing bacteria were screened and isolated. α-galactosidase from different bacterial isolates was purified by ammonium sulphate precipitation of 45% and 65% saturation and further purified by gel filteration chromatography using Saphadex G-100. Optimization of temperature and pH was determined as 40 o C and 7.0 respectively. Effect of metallic ions on α-galactosidase was also investigated.

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