Sylvie Gadeyne - Profile on Academia.edu (original) (raw)
Papers by Sylvie Gadeyne
Essential Driven Elements of African Student Mobility from Africa to China during 1999-2015
Social Science Research Network, 2022
Background: Residing in greener areas may decrease the burden of chronic diseases, but the associ... more Background: Residing in greener areas may decrease the burden of chronic diseases, but the association with cancer is unclear. We studied the associations between residential green spaces and site-specific cancer mortality in urban Belgium. Methodology: We linked the 2001 Belgian census, register mortality data for 2001-2014, and environmental information (green spaces and air pollution) at baseline residence (2001). We included residents from the largest Belgian urban areas aged ≥ 30 years at baseline. Exposure to residential green spaces was assessed using the Normalized Difference Vegetation Index (NDVI), Urban Atlas, and perceived neighbourhood greenness (from the census). We used Cox proportional hazards models to obtain hazard ratios (HR) and their 95 % confidence intervals (95 %CI) of the mortality risk from lung, colorectal, breast (in women) and prostate cancer (in men) per interquartile range increment in residential green spaces. We further analyzed the role of outdoor air pollution and effect modification by age and socioeconomic position (SEP) in main associations. Results: 2,441,566 individuals were included at baseline. During follow-up, 1.2 % died from lung cancer, 0.6 % from colorectal cancer, 0.8 % from breast cancer, and 0.6 % from prostate cancer. After adjustment, higher exposure to green spaces was associated with a reduced mortality risk from lung cancer and breast cancer [e.g., for NDVI within 300 m, HR:0.946 (95 %CI:0.924,0.970), and HR:0.927 (95 %CI:0.892,0.963), respectively], but not with colorectal or prostate cancer mortality. For the latter, a suggestive hazardous effect of green spaces was found. Air pollution seemed to have only a marginal role. Beneficial effects of greenspace were generally stronger in < 65-year-old, but no clear trend by SEP was found. Conclusions: Our findings suggest that residing in green areas could decrease mortality risk from lung and breast cancer, potentially independent from air pollution. Future studies should consider different indicators of greenspace exposure and investigate potential pathways underlying the associations.
The Driving Element of South-to-South Student Mobility from Africa to China 1999-2015
Transversale analyse van de vruchtbaarheid en regionale differentiatie
Bevolking en Gezin, 2000
PLOS ONE, Oct 7, 2022
The Democratic Republic of Congo (DRC) has experienced high levels of unmet need for family plann... more The Democratic Republic of Congo (DRC) has experienced high levels of unmet need for family planning (UNFP) for many years, alongside high fertility, maternal and infant mortality rates. Previous research addressed the UNFP in DRC, but analyses were limited to the individual-level and to specific regions. This study aims to determine the individual-and community-level factors associated with UNFP among married women of reproductive age in DRC. Using data from the 2014 DRC Demographic and Health Survey, a two-level mixed-effect logistic model examined i) the associations between UNFP and individual-and community level factors, and ii) the extent to which individual variability in UNFP is due to the variability observed at the community-level, given the individual characteristics. A total of 10,415 women in 539 clusters were included. Prevalence of unmet need for limiting was 8.13%, and 23.81% for spacing. Compared to adolescents (15-24), young (25-34) (aOR = 0.75, CI: 0.63-0.90) and middle-aged (35-49) (aOR = 0.65, CI: 0.51-0.82) women were less likely to have unmet need for family planning. The odds of having unmet need increased significantly with number of living children [1-2 children (aOR = 2.46, CI: 1.81-3.35), 7+ children (aOR = 6.46, CI: 4.28-9.73)] and among women in a female-headed household (aOR
Socioeconomic inequalities and cancer in Belgium
Urban green spaces and suicide mortality in Belgium (2001-2011): a census-based longitudinal study
Environmental health perspectives, Sep 18, 2022
Social Disparities in Survival from Head and Neck Cancers in Europe
Springer eBooks, 2021
Much has been written about the social disparities in incidence and mortality from head and neck ... more Much has been written about the social disparities in incidence and mortality from head and neck cancer, but comparatively, little is understood about how socioeconomic factors affect survival. As a major form of cancer incidence in Europe, it is important to more fully contextualise the social effects on survival from this complex disease. We conducted a systematic review of the literature on social disparities and head and neck cancer survival in Europe and found clear evidence to support the role of social status on survivability, with those at the lower end of the hierarchy having worse survival outcomes. Tobacco and alcohol (ab)use were the most commonly studied and cited risk factors associated with both social position and length of survival, but it remains evident that much more work is needed to explicate the exact ways these and other less-studied risks directly impact survival.
Research Square (Research Square), Feb 7, 2022
Living in greener areas is associated with slower cognitive decline and reduced dementia risk amo... more Living in greener areas is associated with slower cognitive decline and reduced dementia risk among the elderly, but the evidence with neurodegenerative disease mortality is scarce. We studied the association between residential surrounding greenness and neurodegenerative disease mortality in an elderly population. We used data from the 2001 Belgian census linked to mortality register data during 2001-2014. We included individuals aged 60 years or older and residing in the ve largest Belgian urban areas at baseline (2001). Exposure to residential surrounding greenness was assessed using the Normalized Difference Vegetation Index (NDVI) within 500-m from residence. We considered all neurodegenerative diseases and four speci c outcomes: Alzheimer's disease, vascular dementia, unspeci ed dementia, and Parkinson's disease. We tted Cox proportional hazard models to obtain hazard ratios (HR) and 95% con dence intervals (CI) of the associations between one interquartile range (IQR) increment in surrounding greenness and neurodegenerative disease mortality outcomes. Furthermore, we conducted mediation analyses to assess potential mediation by air pollution (PM 2.5 ), and strati cation analyses to explore effect modi cation by sociodemographic characteristics. From 1,134,502 individuals included at baseline, 6.1% died from neurodegenerative diseases during followup. After full adjustment, one IQR (0.22) increment of surrounding greenness was associated with a 4-5% reduction in premature mortality from neurodegenerative diseases, Alzheimer's disease, vascular and unspeci ed dementia [e.g., for Alzheimer's disease mortality: HR 0.95 (95%CI: 0.93, 0.98)]. No association was found with Parkinson's disease mortality. Reductions in air pollution concentrations could potentially mediate 58% (95%CI: 31.7%, 95.7%) of the observed effect with all neurodegenerative disease mortality. Associations were strongest in the lower educated and residents from most deprived neighbourhoods. Living near greener spaces may reduce the risk of neurodegenerative disease mortality among the elderly, partly mediated by a reduction in air pollution concentrations. Socioeconomically disadvantaged groups may experience the greatest bene cial effect.
Gezondheid en Sterfte(Health and mortality)
Essential driven Elements of African Student Mobility from Africa to China 1999-2015 – A South to South migration perspective
Socioeconomic Inequalities In Health-related Outcomes Of Green Spaces In The Brussels Capital Region: An Intersectional Approach
Socioeconomic inequalities and cancer in Belgium
Additional file 3: Table S1. of The geographic pattern of Belgian mortality: can socio-economic characteristics explain area differences?
All-cause Mortality Rate Ratios (MRRs) and 95Â % confidence intervals (CIs) by district controlle... more All-cause Mortality Rate Ratios (MRRs) and 95Â % confidence intervals (CIs) by district controlled for age, before and after adjustment for individual socio-economic position and household position (Belgium, 2001â 2011). (DOCX 118 kb)
BMJ Open, May 1, 2023
Introduction Data linkage systems have proven to be a powerful tool in support of combating and m... more Introduction Data linkage systems have proven to be a powerful tool in support of combating and managing the COVID-19 pandemic. However, the interoperability and the reuse of different data sources may pose a number of technical, administrative and data security challenges. Methods and analysis This protocol aims to provide a case study for linking highly sensitive individual-level information. We describe the data linkages between health surveillance records and administrative data sources necessary to investigate social health inequalities and the long-term health impact of COVID-19 in Belgium. Data at the national institute for public health, Statistics Belgium and InterMutualistic Agency are used to develop a representative case-cohort study of 1.2 million randomly selected Belgians and 4.5 million Belgians with a confirmed COVID-19 diagnosis (PCR or antigen test), of which 108 211 are COVID-19 hospitalised patients (PCR or antigen test). Yearly updates are scheduled over a period of 4 years. The data set covers inpandemic and postpandemic health information between July 2020 and January 2026, as well as sociodemographic characteristics, socioeconomic indicators, healthcare use and related costs. Two main research questions will be addressed. First, can we identify socioeconomic and sociodemographic risk factors in COVID-19 testing, infection, hospitalisations and mortality? Second, what is the medium-term and long-term health impact of COVID-19 infections and hospitalisations? More specific objectives are (2a) To compare healthcare expenditure during and after a COVID-19 infection or hospitalisation; (2b) To investigate long-term health complications or premature mortality after a COVID-19 infection or hospitalisation; and (2c) To validate the administrative COVID-19 reimbursement nomenclature. The analysis plan includes the calculation of absolute and relative risks using survival analysis methods. Ethics and dissemination This study involves human participants and was approved by Ghent University hospital ethics committee: reference B.U.N. 1432020000371 and the Belgian Information Security Committee: reference Beraadslaging nr. 22/014 van 11 January 2022, available via https://www.ehealth.fgov.be/ehealthplatform/file/ view/AX54CWc4Fbc33iE1rY5a?filename=22-014-n034-HELICON-project.pdf. Dissemination activities include peer-reviewed publications, a webinar series and a project website. The pseudonymised data are derived from administrative and health sources. Acquiring informed consent would require extra information on the subjects. The research team is prohibited from gaining additional knowledge on the study subjects by the Belgian Information Security Committee's interpretation of the Belgian privacy framework.
Socioeconomic differentials in lung cancer mortality in Belgian men and women (2004-2005): does it matter who you live with?
Regional and socioeconomic inequalities in lung cancer mortality in Belgium (Flanders and Brussels-Capital Region, 2001-2009)
Introduction Lung cancer is a leading cause of cancer death and lung cancer mortality among Belgi... more Introduction Lung cancer is a leading cause of cancer death and lung cancer mortality among Belgian men is the highest in Europe. The association between lung cancer and socioeconomic status has been extensively studied, however, little research has focused on geographical differences in lung cancer mortality. Spatial analysis can provide insight into at risk regions and populations, which could aid health interventions, and can help to develop or prove hypothesis about key determinants …
Fertility change among Turkish and Moroccan women in Belgium: results from census data
The determinants of fertility in India. Aggregated and individual analysis based on the National Family and Health Survey, 1992-93
Essential Driven Elements of African Student Mobility from Africa to China during 1999-2015
Social Science Research Network, 2022
Background: Residing in greener areas may decrease the burden of chronic diseases, but the associ... more Background: Residing in greener areas may decrease the burden of chronic diseases, but the association with cancer is unclear. We studied the associations between residential green spaces and site-specific cancer mortality in urban Belgium. Methodology: We linked the 2001 Belgian census, register mortality data for 2001-2014, and environmental information (green spaces and air pollution) at baseline residence (2001). We included residents from the largest Belgian urban areas aged ≥ 30 years at baseline. Exposure to residential green spaces was assessed using the Normalized Difference Vegetation Index (NDVI), Urban Atlas, and perceived neighbourhood greenness (from the census). We used Cox proportional hazards models to obtain hazard ratios (HR) and their 95 % confidence intervals (95 %CI) of the mortality risk from lung, colorectal, breast (in women) and prostate cancer (in men) per interquartile range increment in residential green spaces. We further analyzed the role of outdoor air pollution and effect modification by age and socioeconomic position (SEP) in main associations. Results: 2,441,566 individuals were included at baseline. During follow-up, 1.2 % died from lung cancer, 0.6 % from colorectal cancer, 0.8 % from breast cancer, and 0.6 % from prostate cancer. After adjustment, higher exposure to green spaces was associated with a reduced mortality risk from lung cancer and breast cancer [e.g., for NDVI within 300 m, HR:0.946 (95 %CI:0.924,0.970), and HR:0.927 (95 %CI:0.892,0.963), respectively], but not with colorectal or prostate cancer mortality. For the latter, a suggestive hazardous effect of green spaces was found. Air pollution seemed to have only a marginal role. Beneficial effects of greenspace were generally stronger in < 65-year-old, but no clear trend by SEP was found. Conclusions: Our findings suggest that residing in green areas could decrease mortality risk from lung and breast cancer, potentially independent from air pollution. Future studies should consider different indicators of greenspace exposure and investigate potential pathways underlying the associations.
The Driving Element of South-to-South Student Mobility from Africa to China 1999-2015
Transversale analyse van de vruchtbaarheid en regionale differentiatie
Bevolking en Gezin, 2000
PLOS ONE, Oct 7, 2022
The Democratic Republic of Congo (DRC) has experienced high levels of unmet need for family plann... more The Democratic Republic of Congo (DRC) has experienced high levels of unmet need for family planning (UNFP) for many years, alongside high fertility, maternal and infant mortality rates. Previous research addressed the UNFP in DRC, but analyses were limited to the individual-level and to specific regions. This study aims to determine the individual-and community-level factors associated with UNFP among married women of reproductive age in DRC. Using data from the 2014 DRC Demographic and Health Survey, a two-level mixed-effect logistic model examined i) the associations between UNFP and individual-and community level factors, and ii) the extent to which individual variability in UNFP is due to the variability observed at the community-level, given the individual characteristics. A total of 10,415 women in 539 clusters were included. Prevalence of unmet need for limiting was 8.13%, and 23.81% for spacing. Compared to adolescents (15-24), young (25-34) (aOR = 0.75, CI: 0.63-0.90) and middle-aged (35-49) (aOR = 0.65, CI: 0.51-0.82) women were less likely to have unmet need for family planning. The odds of having unmet need increased significantly with number of living children [1-2 children (aOR = 2.46, CI: 1.81-3.35), 7+ children (aOR = 6.46, CI: 4.28-9.73)] and among women in a female-headed household (aOR
Socioeconomic inequalities and cancer in Belgium
Urban green spaces and suicide mortality in Belgium (2001-2011): a census-based longitudinal study
Environmental health perspectives, Sep 18, 2022
Social Disparities in Survival from Head and Neck Cancers in Europe
Springer eBooks, 2021
Much has been written about the social disparities in incidence and mortality from head and neck ... more Much has been written about the social disparities in incidence and mortality from head and neck cancer, but comparatively, little is understood about how socioeconomic factors affect survival. As a major form of cancer incidence in Europe, it is important to more fully contextualise the social effects on survival from this complex disease. We conducted a systematic review of the literature on social disparities and head and neck cancer survival in Europe and found clear evidence to support the role of social status on survivability, with those at the lower end of the hierarchy having worse survival outcomes. Tobacco and alcohol (ab)use were the most commonly studied and cited risk factors associated with both social position and length of survival, but it remains evident that much more work is needed to explicate the exact ways these and other less-studied risks directly impact survival.
Research Square (Research Square), Feb 7, 2022
Living in greener areas is associated with slower cognitive decline and reduced dementia risk amo... more Living in greener areas is associated with slower cognitive decline and reduced dementia risk among the elderly, but the evidence with neurodegenerative disease mortality is scarce. We studied the association between residential surrounding greenness and neurodegenerative disease mortality in an elderly population. We used data from the 2001 Belgian census linked to mortality register data during 2001-2014. We included individuals aged 60 years or older and residing in the ve largest Belgian urban areas at baseline (2001). Exposure to residential surrounding greenness was assessed using the Normalized Difference Vegetation Index (NDVI) within 500-m from residence. We considered all neurodegenerative diseases and four speci c outcomes: Alzheimer's disease, vascular dementia, unspeci ed dementia, and Parkinson's disease. We tted Cox proportional hazard models to obtain hazard ratios (HR) and 95% con dence intervals (CI) of the associations between one interquartile range (IQR) increment in surrounding greenness and neurodegenerative disease mortality outcomes. Furthermore, we conducted mediation analyses to assess potential mediation by air pollution (PM 2.5 ), and strati cation analyses to explore effect modi cation by sociodemographic characteristics. From 1,134,502 individuals included at baseline, 6.1% died from neurodegenerative diseases during followup. After full adjustment, one IQR (0.22) increment of surrounding greenness was associated with a 4-5% reduction in premature mortality from neurodegenerative diseases, Alzheimer's disease, vascular and unspeci ed dementia [e.g., for Alzheimer's disease mortality: HR 0.95 (95%CI: 0.93, 0.98)]. No association was found with Parkinson's disease mortality. Reductions in air pollution concentrations could potentially mediate 58% (95%CI: 31.7%, 95.7%) of the observed effect with all neurodegenerative disease mortality. Associations were strongest in the lower educated and residents from most deprived neighbourhoods. Living near greener spaces may reduce the risk of neurodegenerative disease mortality among the elderly, partly mediated by a reduction in air pollution concentrations. Socioeconomically disadvantaged groups may experience the greatest bene cial effect.
Gezondheid en Sterfte(Health and mortality)
Essential driven Elements of African Student Mobility from Africa to China 1999-2015 – A South to South migration perspective
Socioeconomic Inequalities In Health-related Outcomes Of Green Spaces In The Brussels Capital Region: An Intersectional Approach
Socioeconomic inequalities and cancer in Belgium
Additional file 3: Table S1. of The geographic pattern of Belgian mortality: can socio-economic characteristics explain area differences?
All-cause Mortality Rate Ratios (MRRs) and 95Â % confidence intervals (CIs) by district controlle... more All-cause Mortality Rate Ratios (MRRs) and 95Â % confidence intervals (CIs) by district controlled for age, before and after adjustment for individual socio-economic position and household position (Belgium, 2001â 2011). (DOCX 118 kb)
BMJ Open, May 1, 2023
Introduction Data linkage systems have proven to be a powerful tool in support of combating and m... more Introduction Data linkage systems have proven to be a powerful tool in support of combating and managing the COVID-19 pandemic. However, the interoperability and the reuse of different data sources may pose a number of technical, administrative and data security challenges. Methods and analysis This protocol aims to provide a case study for linking highly sensitive individual-level information. We describe the data linkages between health surveillance records and administrative data sources necessary to investigate social health inequalities and the long-term health impact of COVID-19 in Belgium. Data at the national institute for public health, Statistics Belgium and InterMutualistic Agency are used to develop a representative case-cohort study of 1.2 million randomly selected Belgians and 4.5 million Belgians with a confirmed COVID-19 diagnosis (PCR or antigen test), of which 108 211 are COVID-19 hospitalised patients (PCR or antigen test). Yearly updates are scheduled over a period of 4 years. The data set covers inpandemic and postpandemic health information between July 2020 and January 2026, as well as sociodemographic characteristics, socioeconomic indicators, healthcare use and related costs. Two main research questions will be addressed. First, can we identify socioeconomic and sociodemographic risk factors in COVID-19 testing, infection, hospitalisations and mortality? Second, what is the medium-term and long-term health impact of COVID-19 infections and hospitalisations? More specific objectives are (2a) To compare healthcare expenditure during and after a COVID-19 infection or hospitalisation; (2b) To investigate long-term health complications or premature mortality after a COVID-19 infection or hospitalisation; and (2c) To validate the administrative COVID-19 reimbursement nomenclature. The analysis plan includes the calculation of absolute and relative risks using survival analysis methods. Ethics and dissemination This study involves human participants and was approved by Ghent University hospital ethics committee: reference B.U.N. 1432020000371 and the Belgian Information Security Committee: reference Beraadslaging nr. 22/014 van 11 January 2022, available via https://www.ehealth.fgov.be/ehealthplatform/file/ view/AX54CWc4Fbc33iE1rY5a?filename=22-014-n034-HELICON-project.pdf. Dissemination activities include peer-reviewed publications, a webinar series and a project website. The pseudonymised data are derived from administrative and health sources. Acquiring informed consent would require extra information on the subjects. The research team is prohibited from gaining additional knowledge on the study subjects by the Belgian Information Security Committee's interpretation of the Belgian privacy framework.
Socioeconomic differentials in lung cancer mortality in Belgian men and women (2004-2005): does it matter who you live with?
Regional and socioeconomic inequalities in lung cancer mortality in Belgium (Flanders and Brussels-Capital Region, 2001-2009)
Introduction Lung cancer is a leading cause of cancer death and lung cancer mortality among Belgi... more Introduction Lung cancer is a leading cause of cancer death and lung cancer mortality among Belgian men is the highest in Europe. The association between lung cancer and socioeconomic status has been extensively studied, however, little research has focused on geographical differences in lung cancer mortality. Spatial analysis can provide insight into at risk regions and populations, which could aid health interventions, and can help to develop or prove hypothesis about key determinants …
Fertility change among Turkish and Moroccan women in Belgium: results from census data
The determinants of fertility in India. Aggregated and individual analysis based on the National Family and Health Survey, 1992-93