Jamal Uddin | The University Of Glasgow (original) (raw)
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Papers by Jamal Uddin
Background: Cardiovascular diseases, mainly coronary heart disease is one of the leading causes o... more Background: Cardiovascular diseases, mainly coronary heart disease is one of the leading causes of death in Bangladesh and increasing in epidemic proportion in time. Objective: To identify and quantify risk factors among the coronary heart disease patients attending at tertiary level hospitals. Methods: A cross-sectional study was carried out among 144 diagnosed CHD patients who were admitted in different tertiary level hospitals in Dhaka city during March to June 2010. The respondents were selected through purposive sampling for interview and data were collected by face to face interview. Patients record file were also reviewed using checklists. Data were analyzed by SPSS version 16.0 and presented in tables and graphs. Results: The mean age of the respondents were 55.26 ±12.35 years. More than two-third (69%) of the respondents were exposed to smoking. Majority (85%) were physically inactive. The recommended intake of fruits and vegetables by the respondents were low (30%). About ...
Journal of Cardiopulmonary Rehabilitation and Prevention, 2019
Ibrahim Cardiac Medical Journal
Background & objective : Coronary artery bypass graft (CABG) surgery has given symptomatic and st... more Background & objective : Coronary artery bypass graft (CABG) surgery has given symptomatic and structural release of coronary atherosclerotic heart disease. CABG has been performed frequently for more than 30 years in Bangladesh. But there are no nationwide studies on the rate of survival in Bangladesh. The present study was undertaken to find the post CABG surgery survival outcomes and association between risk factors and survival over long time span. Methods: We studied 650 consecutive patients’ post-operative clinical data retrospectively and survival outcome data were collected prospectively who had CABG surgery from 2010 to 2015 in Ibrahim Cardiac Hospital & Research Institute. Of the 650 patients, 84(12.9%) died after a median follow up of 4.9 years. Demographic, clinical, operative and postoperative characteristics were then compared between survived and died patients to find the factors associated with survival. Result: Analysis revealed that younger patients were more likel...
Bangladesh Medical Research Council Bulletin
Background: Previous trials showed that diabetic patients had worse in-hospital and long term out... more Background: Previous trials showed that diabetic patients had worse in-hospital and long term outcome after coronary artery bypass grafting (CABG) than non diabetic ones. However, the majority of such studies was carried out in western countries and limited information is available for the Asian population. Objective: The present study was intended to determine the impact of diabetes on early and mid-term outcome among patients undergoing CABG surgery in a tertiary care hospital in Bangladesh. Methods: This study was performed at Ibrahim Cardiac Hospital & Research Institute, Dhaka, Bangladesh, from January to June 2014. Based on enrollment criteria, 202 patients (115 diabeticsand 87 non-diabetics) were enrolled and evaluated for their early outcome (within 30 days of operation) and midterm (after 30 days post-operatively). Patients with known diabetes or preoperative fasting blood sugar ≥6.4 mmol/L or random blood sugar ≥11.1 mmol/L were considered as diabetics. The outcome measure...
JACC. Heart failure, 2018
This study sought to validate exercise capacity (EC) as a surrogate for mortality, hospitalizatio... more This study sought to validate exercise capacity (EC) as a surrogate for mortality, hospitalization, and health-related quality of life (HRQOL). EC is often used as a primary outcome in exercise-based cardiac rehabilitation (CR) trials of heart failure (HF) via direct cardiorespiratory assessment of maximum oxygen uptake (Vopeak) or through submaximal tests, such as the 6-min walk test (6MWT). After a systematic review, 31 randomized trials of exercise-based CR compared with no exercise control (4,784 HF patients) were included. Outcomes were pooled using random effects meta-analyses, and inverse variance weighted linear regression equations were fitted to estimate the relationship between the CR on EC and all-cause mortality, hospitalization, and HRQOL. Spearman correlation coefficient (ρ), R at trial level, and surrogate threshold effect (STE) were calculated. STE represents the intercept of the prediction band of the regression line with null effect on the final outcome. Exercise-...
Background: The aim of this study was to undertake a comprehensive assessment of the patient, int... more Background: The aim of this study was to undertake a comprehensive assessment of the patient, intervention and trial-level factors that may predict exercise capacity following exercise-based rehabilitation in patients with coronary heart disease and heart failure. Design: Meta-analysis and meta-regression analysis. Methods: Randomized controlled trials of exercise-based rehabilitation were identified from three published systematic reviews. Exercise capacity was pooled across trials using random effects meta-analysis, and meta-regression used to examine the association between exercise capacity and a range of patient (e.g. age), intervention (e.g. exercise frequency) and trial (e.g. risk of bias) factors. Results: 55 trials (61 exercise-control comparisons, 7553 patients) were included. Following exercise-based rehabilitation compared to control, overall exercise capacity was on average 0.95 (95% CI: 0.76–1.41) standard deviation units higher, and in trials reporting maximum oxygen uptake (VO 2 max) was 3.3 ml/kg.min À1 (95% CI: 2.6–4.0) higher. There was evidence of a high level of statistical heterogeneity across trials (I 2 statistic > 50%). In multivariable meta-regression analysis, only exercise intervention intensity was found to be significantly associated with VO 2 max (P ¼ 0.04); those trials with the highest average exercise intensity had the largest mean post-rehabilitation VO 2 max compared to control. Conclusions: We found considerable heterogeneity across randomized controlled trials in the magnitude of improvement in exercise capacity following exercise-based rehabilitation compared to control among patients with coronary heart disease or heart failure. Whilst higher exercise intensities were associated with a greater level of post-rehabilitation exercise capacity, there was no strong evidence to support other intervention, patient or trial factors to be predictive.
ABSTRACT Risk Factors among the Coronary Heart Diseases (CHD) among Patients Attending at Tertiar... more ABSTRACT
Risk Factors among the Coronary Heart Diseases (CHD) among Patients Attending at Tertiary Level Hospitals of Dhaka City, Bangladesh
(Trisha N E S, Rahman S M M, Uddin M J, Moniruzzaman, Karim M R, M S A Mansur Ahmed)
Background: Cardiovascular diseases, mainly coronary heart disease is one of the leading causes of death in Bangladesh and increasing in epidemic proportion in time.
Objective: To identify and quantify risk factors among the coronary heart disease patients attending at tertiary level hospitals.
Methods: A cross-sectional study was carried out among 144 diagnosed CHD patients who were admitted in different tertiary level hospitals in Dhaka city during March to June 2010. The respondents were selected through purposive sampling for interview and data were collected by face to face interview. Patients record file were also reviewed using checklists. Data were analyzed by SPSS version 16.0 and presented in tables and graphs.
Results: The mean age of the respondents were 55.26 ±12.35 years. More than two-third (69%) of the respondents were exposed to smoking. Majority (85%) were physically inactive. The recommended intake of fruits and vegetables by the respondents were low (30%). About 60% of the respondents were found to intake extra table salt. The percentage of overweight and obesity was high (67%) with higher proportion of women (82.1%) than men (62.9%). About two-third of the respondents (65%) were with higher level of cholesterol. The prevalence of diabetes mellitus and hypertension were 36% and 51 % respectively. Risk factors analysis revealed at least one risk factor was among almost all of the respondents (99.3%) and at least two, three and four risk factors was prevalent among 98.6%, 87.5% and 66.7% of the respondent respectively.
Conclusion: A substantial proportion of different behavioral, biological and biochemical risk factors were present among coronary heart disease patient that suggests the need for ongoing monitoring of CHD risk factors and implementation of effective preventive strategies for reducing secondary events and its consequences.
KEY WORDS:
Coronary Heart disease, Risk factors
Systematic review by Jamal Uddin
Background: Cardiovascular diseases, mainly coronary heart disease is one of the leading causes o... more Background: Cardiovascular diseases, mainly coronary heart disease is one of the leading causes of death in Bangladesh and increasing in epidemic proportion in time. Objective: To identify and quantify risk factors among the coronary heart disease patients attending at tertiary level hospitals. Methods: A cross-sectional study was carried out among 144 diagnosed CHD patients who were admitted in different tertiary level hospitals in Dhaka city during March to June 2010. The respondents were selected through purposive sampling for interview and data were collected by face to face interview. Patients record file were also reviewed using checklists. Data were analyzed by SPSS version 16.0 and presented in tables and graphs. Results: The mean age of the respondents were 55.26 ±12.35 years. More than two-third (69%) of the respondents were exposed to smoking. Majority (85%) were physically inactive. The recommended intake of fruits and vegetables by the respondents were low (30%). About ...
Journal of Cardiopulmonary Rehabilitation and Prevention, 2019
Ibrahim Cardiac Medical Journal
Background & objective : Coronary artery bypass graft (CABG) surgery has given symptomatic and st... more Background & objective : Coronary artery bypass graft (CABG) surgery has given symptomatic and structural release of coronary atherosclerotic heart disease. CABG has been performed frequently for more than 30 years in Bangladesh. But there are no nationwide studies on the rate of survival in Bangladesh. The present study was undertaken to find the post CABG surgery survival outcomes and association between risk factors and survival over long time span. Methods: We studied 650 consecutive patients’ post-operative clinical data retrospectively and survival outcome data were collected prospectively who had CABG surgery from 2010 to 2015 in Ibrahim Cardiac Hospital & Research Institute. Of the 650 patients, 84(12.9%) died after a median follow up of 4.9 years. Demographic, clinical, operative and postoperative characteristics were then compared between survived and died patients to find the factors associated with survival. Result: Analysis revealed that younger patients were more likel...
Bangladesh Medical Research Council Bulletin
Background: Previous trials showed that diabetic patients had worse in-hospital and long term out... more Background: Previous trials showed that diabetic patients had worse in-hospital and long term outcome after coronary artery bypass grafting (CABG) than non diabetic ones. However, the majority of such studies was carried out in western countries and limited information is available for the Asian population. Objective: The present study was intended to determine the impact of diabetes on early and mid-term outcome among patients undergoing CABG surgery in a tertiary care hospital in Bangladesh. Methods: This study was performed at Ibrahim Cardiac Hospital & Research Institute, Dhaka, Bangladesh, from January to June 2014. Based on enrollment criteria, 202 patients (115 diabeticsand 87 non-diabetics) were enrolled and evaluated for their early outcome (within 30 days of operation) and midterm (after 30 days post-operatively). Patients with known diabetes or preoperative fasting blood sugar ≥6.4 mmol/L or random blood sugar ≥11.1 mmol/L were considered as diabetics. The outcome measure...
JACC. Heart failure, 2018
This study sought to validate exercise capacity (EC) as a surrogate for mortality, hospitalizatio... more This study sought to validate exercise capacity (EC) as a surrogate for mortality, hospitalization, and health-related quality of life (HRQOL). EC is often used as a primary outcome in exercise-based cardiac rehabilitation (CR) trials of heart failure (HF) via direct cardiorespiratory assessment of maximum oxygen uptake (Vopeak) or through submaximal tests, such as the 6-min walk test (6MWT). After a systematic review, 31 randomized trials of exercise-based CR compared with no exercise control (4,784 HF patients) were included. Outcomes were pooled using random effects meta-analyses, and inverse variance weighted linear regression equations were fitted to estimate the relationship between the CR on EC and all-cause mortality, hospitalization, and HRQOL. Spearman correlation coefficient (ρ), R at trial level, and surrogate threshold effect (STE) were calculated. STE represents the intercept of the prediction band of the regression line with null effect on the final outcome. Exercise-...
Background: The aim of this study was to undertake a comprehensive assessment of the patient, int... more Background: The aim of this study was to undertake a comprehensive assessment of the patient, intervention and trial-level factors that may predict exercise capacity following exercise-based rehabilitation in patients with coronary heart disease and heart failure. Design: Meta-analysis and meta-regression analysis. Methods: Randomized controlled trials of exercise-based rehabilitation were identified from three published systematic reviews. Exercise capacity was pooled across trials using random effects meta-analysis, and meta-regression used to examine the association between exercise capacity and a range of patient (e.g. age), intervention (e.g. exercise frequency) and trial (e.g. risk of bias) factors. Results: 55 trials (61 exercise-control comparisons, 7553 patients) were included. Following exercise-based rehabilitation compared to control, overall exercise capacity was on average 0.95 (95% CI: 0.76–1.41) standard deviation units higher, and in trials reporting maximum oxygen uptake (VO 2 max) was 3.3 ml/kg.min À1 (95% CI: 2.6–4.0) higher. There was evidence of a high level of statistical heterogeneity across trials (I 2 statistic > 50%). In multivariable meta-regression analysis, only exercise intervention intensity was found to be significantly associated with VO 2 max (P ¼ 0.04); those trials with the highest average exercise intensity had the largest mean post-rehabilitation VO 2 max compared to control. Conclusions: We found considerable heterogeneity across randomized controlled trials in the magnitude of improvement in exercise capacity following exercise-based rehabilitation compared to control among patients with coronary heart disease or heart failure. Whilst higher exercise intensities were associated with a greater level of post-rehabilitation exercise capacity, there was no strong evidence to support other intervention, patient or trial factors to be predictive.
ABSTRACT Risk Factors among the Coronary Heart Diseases (CHD) among Patients Attending at Tertiar... more ABSTRACT
Risk Factors among the Coronary Heart Diseases (CHD) among Patients Attending at Tertiary Level Hospitals of Dhaka City, Bangladesh
(Trisha N E S, Rahman S M M, Uddin M J, Moniruzzaman, Karim M R, M S A Mansur Ahmed)
Background: Cardiovascular diseases, mainly coronary heart disease is one of the leading causes of death in Bangladesh and increasing in epidemic proportion in time.
Objective: To identify and quantify risk factors among the coronary heart disease patients attending at tertiary level hospitals.
Methods: A cross-sectional study was carried out among 144 diagnosed CHD patients who were admitted in different tertiary level hospitals in Dhaka city during March to June 2010. The respondents were selected through purposive sampling for interview and data were collected by face to face interview. Patients record file were also reviewed using checklists. Data were analyzed by SPSS version 16.0 and presented in tables and graphs.
Results: The mean age of the respondents were 55.26 ±12.35 years. More than two-third (69%) of the respondents were exposed to smoking. Majority (85%) were physically inactive. The recommended intake of fruits and vegetables by the respondents were low (30%). About 60% of the respondents were found to intake extra table salt. The percentage of overweight and obesity was high (67%) with higher proportion of women (82.1%) than men (62.9%). About two-third of the respondents (65%) were with higher level of cholesterol. The prevalence of diabetes mellitus and hypertension were 36% and 51 % respectively. Risk factors analysis revealed at least one risk factor was among almost all of the respondents (99.3%) and at least two, three and four risk factors was prevalent among 98.6%, 87.5% and 66.7% of the respondent respectively.
Conclusion: A substantial proportion of different behavioral, biological and biochemical risk factors were present among coronary heart disease patient that suggests the need for ongoing monitoring of CHD risk factors and implementation of effective preventive strategies for reducing secondary events and its consequences.
KEY WORDS:
Coronary Heart disease, Risk factors