Iuliana Ionascu | University of Agronomic Sciences and Veterinary Medicine - Bucharest, Faculty of Veterinary Medicine (original) (raw)
Papers by Iuliana Ionascu
Cytopathology, 1994
In 1982 a monoclonal antibody against the Ki-1 (later designated CD30) antigen was produced'.... more In 1982 a monoclonal antibody against the Ki-1 (later designated CD30) antigen was produced'. It has been shown that the Ki-1 antigen is expressed in 2-10% of cases of non-Hodgkin's l y m p h ~ m a ~ . ~ , which are characteristically of large cell type and might previously have been diagnosed as metastatic carcinoma. In 1989 a monoclonal antibody, designated Ber-H2, directed against a new epitope of the Ki-1 (CD30) antigen, was described4. The Ber-H2 antibody, unlike Ki-1, can be applied to routinely processed, formaldehyde-fixed, paraffin-embedded sections. The Ki-1 -positive anaplastic large cell lymphoma has been included in recent lymphoma classification^^,^. It is thought to represent a heterogeneous group of lymphomas, the characteristic histological features of which are the presence of anaplastic cells, which may appear cohesive, distending the lymph nodes sinuses and subcapsular pace^,^. Not all Ki-1 lymphomas are of large cell type. The Ki-1 antigen has also been shown to be present on Reed-Sternberg cells in Hodgkin's disease' and a proportion of cells in lymphomatoid papulosis, angioimmunoblastic lymphadenopathy and peripheral T cell lymphomas2. The Ki-1 antigen is also expressed by tumour cells in cases of embryonal carcinoma* and in activated lymphocytes in non-neoplastic tissue'.
Zeitschrift für Gastroenterologie, 2017
High-rise syndrome is a general definition of multiple traumatic injuries that cats experience af... more High-rise syndrome is a general definition of multiple traumatic injuries that cats experience after falling from a height of 2 or more floors of high-rise buildings in urban areas. This falling generally results with multiple injuries including thoracic, abdominal, orthopedic and craniomandibular or craniomaxillofacial trauma. The combination of multiple traumatic injuries can be life threatening. 50 cats diagnosed with high-rise syndrome between period December 2021-December
SCiENTIFIC Works Series C Veterinary Medicine Vol.LXIX (1)), 2023
Melting corneal ulcers in dogs develop secondary to the imbalance between proteinases and protein... more Melting corneal ulcers in dogs develop secondary to the imbalance between proteinases and proteinase inhibitors in the healing process of corneal wounds. Common complications of melting corneal ulcers in dogs are descemetocele, staphyloma and uveitis, which can lead loss of vision. Medical records of 342 dogs diagnosed with melting corneal ulcers from May 2013 to November 2022 treated surgically using VetShield® and SoftShield® collagen bandage lenses and third eyelid flap. Dogs included in the study had a clinical diagnosis of melting corneal ulcer without evidence of retinal detachment or lens luxation confirmed by ocular ultrasonography. 204/342 cases (59.65%) of treated dogs regained their vision and corneal transparency; 113/342 cases (33.04%) had corneal fibrosis and pigmentation with improved vision; 17/342 cases (4.97%) had lost vision due to corneal scarring and 8/342 (2.34%) underwent intrascleral prosthesis due to secondary glaucoma as a complication. Placement of bandage collagen lenses and third eyelid flap in melting corneal ulcers in dogs is an easy, straightforward surgical procedure which can be performed by any veterinarian practitioner with good results.
Scientific Works Series C Veterinary Medicine vol.LXIX (1), 2023
Blunt force traumas that are caused by hit-by cars, animal abuse and bite wounds on the thoracic ... more Blunt force traumas that are caused by hit-by cars, animal abuse and bite wounds on the thoracic region can end up with flail chest in dogs. Flail chest, is one of the serious injuries with presence of two or more continuous ribs fractured. As a result, a portion of the thoracic wall with fractured ribs moves paradoxically in inspiration and expiration. According to many previous case reports, mortality rate is high in this life-threatening situation. Patients present in emergency with thoracic pain and shortness of breath (SOB). 9 years old, female Shih-Tzu breed dog clinically presented with severe dyspnea, pain and paradoxical movement of the chest on the left side of the thorax. 24 hours after the patient's stabilization, CT scans revealed loss of the intercostal muscle integrity and 5 ribs fractures on the left thoracic region. After the imagistic certain diagnosis, the dog was taken to reconstructive thoracic surgery.
Scientific Works Series C Veterinary Medicine vol LXIX (1), 2023
Recently used in veterinary medicine, the diode laser represents the surgical option for the enti... more Recently used in veterinary medicine, the diode laser represents the surgical option for the entire eye pathology in dogs and cats. It is indicated in: eyelid tumours, trichiasis, distichiasis, conjunctival tumours, iris melanosis, uveal cysts, iris tumours, intraocular tumours, retrobulbar tumours and glaucoma. The diode laser for veterinary use has programs set for each surgical option, which provides intraoperative comfort for surgeon. The study was conducted over a period of 3 years (November 2019-November 2022) in 161 patients. The favourable postoperative evolution with the absence of complications was highlighted in the case of tumours, uveal cysts, and iris melanosis. In glaucoma cases, transscleral cyclophotocoagulation is not effective, 85% of the cases remained blind. The use of the diode laser in the case of symblepharon highlighted the rapid recurrence accompanied by neovascularization. Experimental using of diode laser in pigmentary keratitis revealed a short period of time with clear cornea after removing the pigmentation and the neovascularization was abundant.
Curtea Veche , 2013
Uveea 6 1. Pupilele 2. Anomaliile congenitale ale uveei Ø Persistenþa membranei pupilare (PMP) Ø ... more Uveea 6 1. Pupilele 2. Anomaliile congenitale ale uveei Ø Persistenþa membranei pupilare (PMP) Ø Aniridia Ø Colobomul irian Ø Heterocromia irianã Ø Chiºtii irieni 3. Inflamaþiile uveei (uveitele sau irido-ciclo-coroiditele) 4. Tumorile uveei CHAPTER Uvea 6 1. Pupils 2. Congenital abnormalities of the uvea Ø Persistent pupillary membrane (PMP) Ø Aniridia Ø Iris coloboma Ø Iris heterochromia Ø Iris cysts 3. Uveal inflammation (uveitis or irido-cyclo-choroiditis) 4. Uveal tumors
Lucrari Stiintifice - Universitatea de Stiinte Agricole a Banatului Timisoara, Medicina Veterinara, 2007
The chronic superficial keratitis in German shepherd or pannus is the subepithelial proliferation... more The chronic superficial keratitis in German shepherd or pannus is the subepithelial proliferation of vessels and connective tissue in cornea. It is a frequent disease in German Shepherd characterized by corneal superficial opacity and gray to red roughened covering this structure of the eye. Although the aetiology of the disease is thought to be immune mediated, the studies made in Surgery Department of the Faculty of Veterinary Medicine revealed that stress is the most important element in trigger and recurrence of the disease.
Practica veterinara.ro, 2022
Feline corneal sequestrum develops secondary to the quantitative or qualitative deficit of the la... more Feline corneal sequestrum develops secondary to the quantitative or qualitative deficit of the lacrimal tear film or represents a sequela in the healing process of corneal ulcers. The classic surgical approach is keratectomy and cornealconjunctival flap for which not only special equipment is required (surgical microscope, cornea surgery kit), but also good knowledge of the technique of corneal sutures. For 32 cats diagnosed with corneal sequestrum (Persian, Exotic Shorthair, British Shorthair and Domestic Shorthair), a new surgical protocol was performed: keratectomy, application of the SoftShield ® collagen contact lens and third eyelid flap. The sutures were maintained for three weeks. The healing of the cornea was achieved with minimal scarring, compared to the cases in which the corneal-conjunctival flap was performed. This surgical technique for feline corneal sequestrum can be performed by any veterinarian because it does not require special equipment or knowledge of corneal suture techniques.
Scientific Works. Series C. Veterinary Medicine, 2015
Endoscopic cyclophotocoagulation (ECP) is a relatively new method of cyclodestruction in the trea... more Endoscopic cyclophotocoagulation (ECP) is a relatively new method of cyclodestruction in the treatment of glaucoma, by lowering IOP through aqueous suppression. Although the coagulation of the ciliary processes using laser is well documented, this new endoscopic approach has numerous benefits comparing to the transscleral cyclophotocoagulation. The paper aims to present a review of the indications, techniques and efficacy of diode ECP. ECP uses a diode laser equipped with an endoscope which permits direct localization and photocoagulation of the ciliary processes. The procedure can be combined with phacoemulsification in patients with coexisting cataract. Other indications of diode endolaser are iridal mass, ciliary body neoplasia, uveal cysts and retinopexy in retinal detachment cases. The available clinical evidence reviewed suggest that ECP is a safe and effective procedure in veterinary ophthalmology.
Scientific Works - University of Agronomical Sciences and Veterinary Medicine, Bucharest. Series C, Veterinary Medicine, 2012
The interruption of sympathetic innervations at the head level is the main cause that produces th... more The interruption of sympathetic innervations at the head level is the main cause that produces the Horner`s syndrome. The damage of the nerve fibres may occur: central, preganglionic or postganglionic. Most patients were sent for an ophthalmologic examination as a result of a sudden attack, often described by owners as "closed, paintful eye". The purpose of this paper is to establish an etiologic differential diagnosis protocol in Horner`s syndrome. The patients examined in the Surgery Clinics of the Faculty of Veterinary Medicine Bucharest presented enophthalmos, upper eyelid ptosis, palpebral slid reduction, third eyelid protrusion and miosis. The ophthalmologic examination was performed by direct methods and indirect methods, as Schirmer test, fluorescein test and the pupil size in the darkness. For the most patients, the disease started suddenly, with epiphora and very painful eye. Only for few of them, the onset was sudden and no ocular pain or epiphora were mentioned. The results of the tests showed normal values for the Schirmer test, miosis, with negative response of the pupil in the darkness. The fluorescein test was negative and the internal face of the third eyelid presented no foreign bodies. In this cases, the etiology of the syndrome is idiopathic or secondary to media otitis, frequently subclinical. It was achieved a diferential diagnosis between Horner`s syndrome and the superficial or deep corneal wounds, when the fluorescein test is positive and there were highlighter foreign bodies at the internal third eyelid.
Cells
Human chorionic gonadotropin (hCG) is produced by the placenta and its roles have been studied fo... more Human chorionic gonadotropin (hCG) is produced by the placenta and its roles have been studied for over a century, being the first known pregnancy-related protein. Although its main role is to stimulate the production of progesterone by corpus luteal cells, hCG does not represent just one biologically active molecule, but a group of at least five variants, produced by different cells and each with different functions. The hyperglycosylated variant of hCG (H-hCG) plays a key role in trophoblast invasion, placental development and fetal growth. During trophoblast invasion, H-hCG promotes extravillous cytotrophoblast cells to infiltrate the decidua, and also to colonize and remodel the spiral arteries in to low resistance, larger-diameter vessels. As fetal growth is heavily reliant on nutrient availability, impaired trophoblast invasion and remodeling of the uterine arteries, leads to a defective perfusion of the placenta and fetal growth restriction. Understanding the function of H-hC...
Revista Română de Medicină Veterinară, 2018
AgroLife Scientific Journal, 2012
Indolent or refractory corneal ulcer is a chronic, superficial, nonhealing erosion, usually affec... more Indolent or refractory corneal ulcer is a chronic, superficial, nonhealing erosion, usually affecting older dogs, especially Boxers. Its characteristics are failure to heal within 1-2 weeks, a poor attachment of the epithelium surrounding the lesion to the corneal stroma and the fluoresceine staining of the affected area. The goals for the treatment of indolent ulcer are removing the loose epithelium, promoting the healing process and protection of the cornea. This article presents the medical treatment of refractory corneal ulcers in dogs and the importance of using contact lenses for reducing the healing time.
Practica veterinara.ro, 2021
Scientific Works - University of Agronomical Sciences and Veterinary Medicine, Bucharest. Series C, Veterinary Medicine, 2012
One of the major goals of anesthesia is control the pain. For far too many years the veterinary p... more One of the major goals of anesthesia is control the pain. For far too many years the veterinary profession has considered analgesia and pain management to be of little interest with practitioners as quoted outdated aphorisms as " animals feel less pain than humans", or "pain is beneficial because it limits movement"and "analgesia mask clinical degeneration ". Now we know that all these are totally false and that pain affects life and rehabilitation of patients in a tremendous way. The aim of this article is to clarify specific conditions that occur in anesthesia following retrobulbar block using as reference parameters : pupillary reflex and position of the eyeball, before and after the block but also the heart rate and non invasive blood pressure.
Practica veterinara.ro, Nov 22, 2021
Scientific Works. Series C. Veterinary Medicine, 2015
Toxoplasmosis is a zoonotic disease caused by the protozoan Toxoplasma gondii, an intracellular c... more Toxoplasmosis is a zoonotic disease caused by the protozoan Toxoplasma gondii, an intracellular coccidian parasite. The cat occupies a central role in the life cycle of this parasite, as a definitive host. Toxoplasmosis is transmitted by consumption of infected raw or undercooked meat, consumption of oocysts from the cat feces or by transplacental transfer of tachyzoites from mother to fetus. The study was conducted in the Ophthalmology Department of the Faculty of Veterinary Medicine, Bucharest, over a one year period, from September 2013 to September 2014. We examined and diagnosed with toxoplasmosis a number of 22 cats. The cases were subjected to clinical, neurological, ocular examinations and paraclinical tests. Clinical examination revealed various multifocal neurological signs such as behavioural changes, altered mentation, seizures, ataxia, blindness, anisocoria, torticollis and vestibular signs. In some cases the ophthalmological examination revealed chorioretinitis and uveitis. These results along with the history led us to the suspicion of toxoplasmosis. We performed routine haematology and serum biochemistry tests, but these tests are not specific and the results depend on the extent of systemic involvement. We established the definitive diagnosis of toxoplasmosis by performing the serological specific test in order to determine the IgM and IgG levels of Toxoplasma antibodies. In the cases were the IgM titre was elevated, the acute phase of the infection was diagnosed, whereas the elevated IgG titre revealed a chronic infection. The aim of this paper is to highlight the multiple and various neurological signs of toxoplasmosis, which is often misdiagnosed and incompletely investigated, and therefore improperly treated. The importance of this study stems from the fact that in recent years toxoplasmosis experienced an increase incidence in our country.
Cytopathology, 1994
In 1982 a monoclonal antibody against the Ki-1 (later designated CD30) antigen was produced'.... more In 1982 a monoclonal antibody against the Ki-1 (later designated CD30) antigen was produced'. It has been shown that the Ki-1 antigen is expressed in 2-10% of cases of non-Hodgkin's l y m p h ~ m a ~ . ~ , which are characteristically of large cell type and might previously have been diagnosed as metastatic carcinoma. In 1989 a monoclonal antibody, designated Ber-H2, directed against a new epitope of the Ki-1 (CD30) antigen, was described4. The Ber-H2 antibody, unlike Ki-1, can be applied to routinely processed, formaldehyde-fixed, paraffin-embedded sections. The Ki-1 -positive anaplastic large cell lymphoma has been included in recent lymphoma classification^^,^. It is thought to represent a heterogeneous group of lymphomas, the characteristic histological features of which are the presence of anaplastic cells, which may appear cohesive, distending the lymph nodes sinuses and subcapsular pace^,^. Not all Ki-1 lymphomas are of large cell type. The Ki-1 antigen has also been shown to be present on Reed-Sternberg cells in Hodgkin's disease' and a proportion of cells in lymphomatoid papulosis, angioimmunoblastic lymphadenopathy and peripheral T cell lymphomas2. The Ki-1 antigen is also expressed by tumour cells in cases of embryonal carcinoma* and in activated lymphocytes in non-neoplastic tissue'.
Zeitschrift für Gastroenterologie, 2017
High-rise syndrome is a general definition of multiple traumatic injuries that cats experience af... more High-rise syndrome is a general definition of multiple traumatic injuries that cats experience after falling from a height of 2 or more floors of high-rise buildings in urban areas. This falling generally results with multiple injuries including thoracic, abdominal, orthopedic and craniomandibular or craniomaxillofacial trauma. The combination of multiple traumatic injuries can be life threatening. 50 cats diagnosed with high-rise syndrome between period December 2021-December
SCiENTIFIC Works Series C Veterinary Medicine Vol.LXIX (1)), 2023
Melting corneal ulcers in dogs develop secondary to the imbalance between proteinases and protein... more Melting corneal ulcers in dogs develop secondary to the imbalance between proteinases and proteinase inhibitors in the healing process of corneal wounds. Common complications of melting corneal ulcers in dogs are descemetocele, staphyloma and uveitis, which can lead loss of vision. Medical records of 342 dogs diagnosed with melting corneal ulcers from May 2013 to November 2022 treated surgically using VetShield® and SoftShield® collagen bandage lenses and third eyelid flap. Dogs included in the study had a clinical diagnosis of melting corneal ulcer without evidence of retinal detachment or lens luxation confirmed by ocular ultrasonography. 204/342 cases (59.65%) of treated dogs regained their vision and corneal transparency; 113/342 cases (33.04%) had corneal fibrosis and pigmentation with improved vision; 17/342 cases (4.97%) had lost vision due to corneal scarring and 8/342 (2.34%) underwent intrascleral prosthesis due to secondary glaucoma as a complication. Placement of bandage collagen lenses and third eyelid flap in melting corneal ulcers in dogs is an easy, straightforward surgical procedure which can be performed by any veterinarian practitioner with good results.
Scientific Works Series C Veterinary Medicine vol.LXIX (1), 2023
Blunt force traumas that are caused by hit-by cars, animal abuse and bite wounds on the thoracic ... more Blunt force traumas that are caused by hit-by cars, animal abuse and bite wounds on the thoracic region can end up with flail chest in dogs. Flail chest, is one of the serious injuries with presence of two or more continuous ribs fractured. As a result, a portion of the thoracic wall with fractured ribs moves paradoxically in inspiration and expiration. According to many previous case reports, mortality rate is high in this life-threatening situation. Patients present in emergency with thoracic pain and shortness of breath (SOB). 9 years old, female Shih-Tzu breed dog clinically presented with severe dyspnea, pain and paradoxical movement of the chest on the left side of the thorax. 24 hours after the patient's stabilization, CT scans revealed loss of the intercostal muscle integrity and 5 ribs fractures on the left thoracic region. After the imagistic certain diagnosis, the dog was taken to reconstructive thoracic surgery.
Scientific Works Series C Veterinary Medicine vol LXIX (1), 2023
Recently used in veterinary medicine, the diode laser represents the surgical option for the enti... more Recently used in veterinary medicine, the diode laser represents the surgical option for the entire eye pathology in dogs and cats. It is indicated in: eyelid tumours, trichiasis, distichiasis, conjunctival tumours, iris melanosis, uveal cysts, iris tumours, intraocular tumours, retrobulbar tumours and glaucoma. The diode laser for veterinary use has programs set for each surgical option, which provides intraoperative comfort for surgeon. The study was conducted over a period of 3 years (November 2019-November 2022) in 161 patients. The favourable postoperative evolution with the absence of complications was highlighted in the case of tumours, uveal cysts, and iris melanosis. In glaucoma cases, transscleral cyclophotocoagulation is not effective, 85% of the cases remained blind. The use of the diode laser in the case of symblepharon highlighted the rapid recurrence accompanied by neovascularization. Experimental using of diode laser in pigmentary keratitis revealed a short period of time with clear cornea after removing the pigmentation and the neovascularization was abundant.
Curtea Veche , 2013
Uveea 6 1. Pupilele 2. Anomaliile congenitale ale uveei Ø Persistenþa membranei pupilare (PMP) Ø ... more Uveea 6 1. Pupilele 2. Anomaliile congenitale ale uveei Ø Persistenþa membranei pupilare (PMP) Ø Aniridia Ø Colobomul irian Ø Heterocromia irianã Ø Chiºtii irieni 3. Inflamaþiile uveei (uveitele sau irido-ciclo-coroiditele) 4. Tumorile uveei CHAPTER Uvea 6 1. Pupils 2. Congenital abnormalities of the uvea Ø Persistent pupillary membrane (PMP) Ø Aniridia Ø Iris coloboma Ø Iris heterochromia Ø Iris cysts 3. Uveal inflammation (uveitis or irido-cyclo-choroiditis) 4. Uveal tumors
Lucrari Stiintifice - Universitatea de Stiinte Agricole a Banatului Timisoara, Medicina Veterinara, 2007
The chronic superficial keratitis in German shepherd or pannus is the subepithelial proliferation... more The chronic superficial keratitis in German shepherd or pannus is the subepithelial proliferation of vessels and connective tissue in cornea. It is a frequent disease in German Shepherd characterized by corneal superficial opacity and gray to red roughened covering this structure of the eye. Although the aetiology of the disease is thought to be immune mediated, the studies made in Surgery Department of the Faculty of Veterinary Medicine revealed that stress is the most important element in trigger and recurrence of the disease.
Practica veterinara.ro, 2022
Feline corneal sequestrum develops secondary to the quantitative or qualitative deficit of the la... more Feline corneal sequestrum develops secondary to the quantitative or qualitative deficit of the lacrimal tear film or represents a sequela in the healing process of corneal ulcers. The classic surgical approach is keratectomy and cornealconjunctival flap for which not only special equipment is required (surgical microscope, cornea surgery kit), but also good knowledge of the technique of corneal sutures. For 32 cats diagnosed with corneal sequestrum (Persian, Exotic Shorthair, British Shorthair and Domestic Shorthair), a new surgical protocol was performed: keratectomy, application of the SoftShield ® collagen contact lens and third eyelid flap. The sutures were maintained for three weeks. The healing of the cornea was achieved with minimal scarring, compared to the cases in which the corneal-conjunctival flap was performed. This surgical technique for feline corneal sequestrum can be performed by any veterinarian because it does not require special equipment or knowledge of corneal suture techniques.
Scientific Works. Series C. Veterinary Medicine, 2015
Endoscopic cyclophotocoagulation (ECP) is a relatively new method of cyclodestruction in the trea... more Endoscopic cyclophotocoagulation (ECP) is a relatively new method of cyclodestruction in the treatment of glaucoma, by lowering IOP through aqueous suppression. Although the coagulation of the ciliary processes using laser is well documented, this new endoscopic approach has numerous benefits comparing to the transscleral cyclophotocoagulation. The paper aims to present a review of the indications, techniques and efficacy of diode ECP. ECP uses a diode laser equipped with an endoscope which permits direct localization and photocoagulation of the ciliary processes. The procedure can be combined with phacoemulsification in patients with coexisting cataract. Other indications of diode endolaser are iridal mass, ciliary body neoplasia, uveal cysts and retinopexy in retinal detachment cases. The available clinical evidence reviewed suggest that ECP is a safe and effective procedure in veterinary ophthalmology.
Scientific Works - University of Agronomical Sciences and Veterinary Medicine, Bucharest. Series C, Veterinary Medicine, 2012
The interruption of sympathetic innervations at the head level is the main cause that produces th... more The interruption of sympathetic innervations at the head level is the main cause that produces the Horner`s syndrome. The damage of the nerve fibres may occur: central, preganglionic or postganglionic. Most patients were sent for an ophthalmologic examination as a result of a sudden attack, often described by owners as "closed, paintful eye". The purpose of this paper is to establish an etiologic differential diagnosis protocol in Horner`s syndrome. The patients examined in the Surgery Clinics of the Faculty of Veterinary Medicine Bucharest presented enophthalmos, upper eyelid ptosis, palpebral slid reduction, third eyelid protrusion and miosis. The ophthalmologic examination was performed by direct methods and indirect methods, as Schirmer test, fluorescein test and the pupil size in the darkness. For the most patients, the disease started suddenly, with epiphora and very painful eye. Only for few of them, the onset was sudden and no ocular pain or epiphora were mentioned. The results of the tests showed normal values for the Schirmer test, miosis, with negative response of the pupil in the darkness. The fluorescein test was negative and the internal face of the third eyelid presented no foreign bodies. In this cases, the etiology of the syndrome is idiopathic or secondary to media otitis, frequently subclinical. It was achieved a diferential diagnosis between Horner`s syndrome and the superficial or deep corneal wounds, when the fluorescein test is positive and there were highlighter foreign bodies at the internal third eyelid.
Cells
Human chorionic gonadotropin (hCG) is produced by the placenta and its roles have been studied fo... more Human chorionic gonadotropin (hCG) is produced by the placenta and its roles have been studied for over a century, being the first known pregnancy-related protein. Although its main role is to stimulate the production of progesterone by corpus luteal cells, hCG does not represent just one biologically active molecule, but a group of at least five variants, produced by different cells and each with different functions. The hyperglycosylated variant of hCG (H-hCG) plays a key role in trophoblast invasion, placental development and fetal growth. During trophoblast invasion, H-hCG promotes extravillous cytotrophoblast cells to infiltrate the decidua, and also to colonize and remodel the spiral arteries in to low resistance, larger-diameter vessels. As fetal growth is heavily reliant on nutrient availability, impaired trophoblast invasion and remodeling of the uterine arteries, leads to a defective perfusion of the placenta and fetal growth restriction. Understanding the function of H-hC...
Revista Română de Medicină Veterinară, 2018
AgroLife Scientific Journal, 2012
Indolent or refractory corneal ulcer is a chronic, superficial, nonhealing erosion, usually affec... more Indolent or refractory corneal ulcer is a chronic, superficial, nonhealing erosion, usually affecting older dogs, especially Boxers. Its characteristics are failure to heal within 1-2 weeks, a poor attachment of the epithelium surrounding the lesion to the corneal stroma and the fluoresceine staining of the affected area. The goals for the treatment of indolent ulcer are removing the loose epithelium, promoting the healing process and protection of the cornea. This article presents the medical treatment of refractory corneal ulcers in dogs and the importance of using contact lenses for reducing the healing time.
Practica veterinara.ro, 2021
Scientific Works - University of Agronomical Sciences and Veterinary Medicine, Bucharest. Series C, Veterinary Medicine, 2012
One of the major goals of anesthesia is control the pain. For far too many years the veterinary p... more One of the major goals of anesthesia is control the pain. For far too many years the veterinary profession has considered analgesia and pain management to be of little interest with practitioners as quoted outdated aphorisms as " animals feel less pain than humans", or "pain is beneficial because it limits movement"and "analgesia mask clinical degeneration ". Now we know that all these are totally false and that pain affects life and rehabilitation of patients in a tremendous way. The aim of this article is to clarify specific conditions that occur in anesthesia following retrobulbar block using as reference parameters : pupillary reflex and position of the eyeball, before and after the block but also the heart rate and non invasive blood pressure.
Practica veterinara.ro, Nov 22, 2021
Scientific Works. Series C. Veterinary Medicine, 2015
Toxoplasmosis is a zoonotic disease caused by the protozoan Toxoplasma gondii, an intracellular c... more Toxoplasmosis is a zoonotic disease caused by the protozoan Toxoplasma gondii, an intracellular coccidian parasite. The cat occupies a central role in the life cycle of this parasite, as a definitive host. Toxoplasmosis is transmitted by consumption of infected raw or undercooked meat, consumption of oocysts from the cat feces or by transplacental transfer of tachyzoites from mother to fetus. The study was conducted in the Ophthalmology Department of the Faculty of Veterinary Medicine, Bucharest, over a one year period, from September 2013 to September 2014. We examined and diagnosed with toxoplasmosis a number of 22 cats. The cases were subjected to clinical, neurological, ocular examinations and paraclinical tests. Clinical examination revealed various multifocal neurological signs such as behavioural changes, altered mentation, seizures, ataxia, blindness, anisocoria, torticollis and vestibular signs. In some cases the ophthalmological examination revealed chorioretinitis and uveitis. These results along with the history led us to the suspicion of toxoplasmosis. We performed routine haematology and serum biochemistry tests, but these tests are not specific and the results depend on the extent of systemic involvement. We established the definitive diagnosis of toxoplasmosis by performing the serological specific test in order to determine the IgM and IgG levels of Toxoplasma antibodies. In the cases were the IgM titre was elevated, the acute phase of the infection was diagnosed, whereas the elevated IgG titre revealed a chronic infection. The aim of this paper is to highlight the multiple and various neurological signs of toxoplasmosis, which is often misdiagnosed and incompletely investigated, and therefore improperly treated. The importance of this study stems from the fact that in recent years toxoplasmosis experienced an increase incidence in our country.
Curtea Veche București, 2023
Copyright 2023 TOATE DREPTURILE REVIN AUTORULUI Toate drepturile asupra cărții aparin autorului. ... more Copyright 2023 TOATE DREPTURILE REVIN AUTORULUI Toate drepturile asupra cărții aparin autorului. Reproducerea integral sau parțială a textului sau a ilustrațiilor din această carte este interzisă fără acordul prealabil scris al autorului. Nicio parte a operei nu poate fi reprodusă, sub nicio formă (prin fotocopiere, microfilm sau un alt procedeu) fără acordul prealabil al autorului și nici salvată, prelucrată, multiplicată, difuzată prin utilizarea de sisteme electronice.
Ex Terra Aurum, București, 2022