Paola Pergami | West Virginia University (original) (raw)

Address: Morgantown, United States

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Papers by Paola Pergami

Research paper thumbnail of Déjérine's syndrome or Spiller's syndrome

Neurological Sciences, 2001

We report the difference existing between two clinical syndromes: Spiller's syndrome is caused by... more We report the difference existing between two clinical syndromes: Spiller's syndrome is caused by a complete involvement of the medial hemimedulla, while Déjérine's syndrome is determined by lesions restricted to the anterior portion of the medial hemimedulla and is characterized by hypoglossal nerve palsy and contralateral hemiparesis.

Research paper thumbnail of Early induction of protein nexin-I in scrapie

Neuroreport, 1999

We used RNA fingerprinting by arbitrary primed PCR to identify genes whose expression is up-regul... more We used RNA fingerprinting by arbitrary primed PCR to identify genes whose expression is up-regulated in the brain of hamsters affected by prion disease. One gene implicated by RNA fingerprinting encoded the hamster homologue of protein nexin-I (PN-I), a serine proteinase inhibitor, and was further investigated by Northern blot analysis. PN-I mRNA levels were increased at pre-clinical stages (19 days after inoculation) and remained elevated when the spongiform encephalopathy was anatomopathologically and clinically evident (at 50 and 80 days). Future RNA screening conducted as illustrated may help to reveal a spectrum of genes relevant for the etiopathogenesis and/or diagnosis of prion disease.

Research paper thumbnail of About the original description of cerebellar tonsil herniation by Pierre Marie

Journal of Neurology Neurosurgery and Psychiatry, 1997

Research paper thumbnail of Paraneoplastic “rubral” tremor: A case report

Research paper thumbnail of Disseminated encephalitis following streptococcal infection

Italian Journal of Neurological Sciences, 1996

Various neurological disorders have been related to Streptococcus pyogenes infection. Only recent... more Various neurological disorders have been related to Streptococcus pyogenes infection. Only recently, and for the first time, it has been suggested that acute disseminated encephalitis may also complicate a streptococcal infection. The case reported in this paper seems to confirm this hypothesis. Varie malattie neurologiche possono essere associate ad infezioni da Streptococco pyogenes. Solo recentemente e per la prima volta à stato segnalato un caso di Encefalomielite Acuta Disseminata come complicanza di infezione Streptococcica. Il caso descritto in questo articolo sembra confermare la possibilità di tale complicazione.

Research paper thumbnail of Elongated Styloid Process and Eagle's Syndrome

Research paper thumbnail of Structural Dependence of the Cellular Isoform of Prion Protein on Solvent: Spectroscopic Characterization of an Intermediate Conformation

Biochemical and Biophysical Research Communications, 1999

Research paper thumbnail of Déjérine's syndrome or Spiller's syndrome

Neurological Sciences, 2001

We report the difference existing between two clinical syndromes: Spiller's syndrome is caused by... more We report the difference existing between two clinical syndromes: Spiller's syndrome is caused by a complete involvement of the medial hemimedulla, while Déjérine's syndrome is determined by lesions restricted to the anterior portion of the medial hemimedulla and is characterized by hypoglossal nerve palsy and contralateral hemiparesis.

Research paper thumbnail of Early induction of protein nexin-I in scrapie

Neuroreport, 1999

We used RNA fingerprinting by arbitrary primed PCR to identify genes whose expression is up-regul... more We used RNA fingerprinting by arbitrary primed PCR to identify genes whose expression is up-regulated in the brain of hamsters affected by prion disease. One gene implicated by RNA fingerprinting encoded the hamster homologue of protein nexin-I (PN-I), a serine proteinase inhibitor, and was further investigated by Northern blot analysis. PN-I mRNA levels were increased at pre-clinical stages (19 days after inoculation) and remained elevated when the spongiform encephalopathy was anatomopathologically and clinically evident (at 50 and 80 days). Future RNA screening conducted as illustrated may help to reveal a spectrum of genes relevant for the etiopathogenesis and/or diagnosis of prion disease.

Research paper thumbnail of About the original description of cerebellar tonsil herniation by Pierre Marie

Journal of Neurology Neurosurgery and Psychiatry, 1997

Research paper thumbnail of Paraneoplastic “rubral” tremor: A case report

Research paper thumbnail of Disseminated encephalitis following streptococcal infection

Italian Journal of Neurological Sciences, 1996

Various neurological disorders have been related to Streptococcus pyogenes infection. Only recent... more Various neurological disorders have been related to Streptococcus pyogenes infection. Only recently, and for the first time, it has been suggested that acute disseminated encephalitis may also complicate a streptococcal infection. The case reported in this paper seems to confirm this hypothesis. Varie malattie neurologiche possono essere associate ad infezioni da Streptococco pyogenes. Solo recentemente e per la prima volta à stato segnalato un caso di Encefalomielite Acuta Disseminata come complicanza di infezione Streptococcica. Il caso descritto in questo articolo sembra confermare la possibilità di tale complicazione.

Research paper thumbnail of Elongated Styloid Process and Eagle's Syndrome

Research paper thumbnail of Structural Dependence of the Cellular Isoform of Prion Protein on Solvent: Spectroscopic Characterization of an Intermediate Conformation

Biochemical and Biophysical Research Communications, 1999

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