Green Synthesis of CuO nanoparticles via Plectranthus amboinicus leaves extract with its characterization on structural, morphological, and biological properties (original) (raw)
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CuO Nanoparticles : Biosynthesis, Characterization and In Vitro Study
2021
The biosynthesis of CuO nanoparticles was studied. The aims of this research were biosynthesis CuO nanoparticles from Cu2+ion solution and leaves aquoeus extract of sweet star fruit and its in vitro study as antibacterial agent of Escherichia coli. CuO nanoparticles was characterized using FTIR spectroscopy and X-Ray diffractometer. CuO nanoparticles was synthesized by reaction between Cu2+ion solution and leaves aquoeus extract of sweet star fruit. Paper disk method was used as the application of the suspension of CuO nanoparticles. The result showed that Cu-O groups detected at wave number of 503, 619, 767 and 821 cm-1. Diffractogram of CuO nanoparticles had sharp and narrow diffraction peaks. The crystallite size of CuO nanoparticles was 4.25 nm. The average inhibition zone of CuO nanoparticles at concentration 10.000, 7.500, 5.000 and 2.500 ppm was 17.43 ± 1.81 ; 15.73 ± 0.40 ; 14.50 ± 2.96 and 9.67 ± 0.28 mm respectively.
International Research Journal of Pharmacy, 2017
Copper oxide (CuO) nanoparticles are known as multifunctional inorganic nanoparticles with a wide range of applications. This work mainly concentrated on the comparative study of antibacterial properties of CuO nanoparticles using two different methods. The green CuO nanoparticles were synthesized from Cajanus Cajan plant leaf extract. The CuO nanoparticles were visually confirmed by the change of color after addition of leaf extract into the copper acetate solution. The synthesized CuO nanoparticles were also characterized by using UV-Vis analysis, Fourier Transform Infrared analysis (FTIR), and X-ray diffraction analysis (XRD), Field Emission Scanning Electron Microscopy (FESEM) Energy Dispersive X-Ray (EDX) analysis. From the results, it is suggested that bio-CuO nanoparticles show more enhanced biocide activity against various human pathogens when compared to chemical CuO nanoparticles.
Green Approach for Synthesis of Cuo Nanoparticles and their Application in Antimicrobial Activity
International Journal of Environmental Sciences & Natural Resources, 2019
With the rapid development of nanotechnology, much has been anticipated with copper oxide nanoparticles (CuO NP) due to their extensive industrial and commercial application. Copper oxide (CuO) nanoparticles have attracted huge attention due to their catalytic, electrical, optical, photonic, textile, nanofluid, and antibacterial activity depending on the size, shape, and neighbouring medium. In the present paper, CuO nanoparticles are synthesized by using eco-friendly and non-toxic plants extract. The CuO nanoparticles are being synthesized by bottom up approach. CuO nanoparticles are used for various anti-bacterial treatments. Green plants extract is used for the efficient synthesis of CuO nanoparticles to obtain significantly active antibacterial material.
Synthesis and evaluation of antioxidant and antibacterial behavior of CuO nanoparticles
Colloids and Surfaces B: Biointerfaces, 2013
In the present work a series of novel coumarin-3-carboxamides and their hybrids with the alpha-lipoic acid were designed, synthesized and tested as potent antioxidant and anti-inflammatory agents. The new compounds were evaluated for their antioxidant activity, their activity to inhibit in vitro lipoxygenase and their in vivo anti-inflammatory activity. In general, the derivatives were generally found to present antioxidant and anti-inflammatory activities. Discussion is made based on the results for the structureactivity relationships in order to define the structural features required for activity. diamine. Yield: 71%; 1 H NMR (CDCl 3 /CF 3 COOD): d ¼ 1.24-1.45 (m, 8H, (CH 2 ) 2 (CH 2 ) 4 (CH 2 ) 2 ), 1.67-1.72 (m, 4H, CH 2 (CH 2 ) 4 CH 2 ), 3.14 (t, J ¼ 6.7 Hz, 2H, CH 2 NH 2 ), 3.46 (t, J ¼ 6.9 Hz, 2H, NHCH 2 ), 7.37 (dd,
We report the synthesis of copper oxide (CuO) nanoparticles by simple chemical precipitation route using the copper acetate precursor. The synthesized CuO nanoparticles were characterized by X-ray powder diffraction (XRD), the synthesized particles were spherical and particle size was in the range of 24 nm. The Fourier-transform infrared (FTIR) results showed the functional groups required for the reduction of copper ions. UV-DRS is reported from the synthesis CuO nanoparticles and optical results show the bandgap energy (E g) is 1.94 eV. The photoluminescence spectrum display a broad emission at 527 nm indicates green emission. The morphology of the product was analyzed by field emission scanning electron microscopy (FE-SEM) and confirmed by high resolution transmission electron microscope (HR-TEM) analysis. The magnetic measurements indicated that the obtained CuO nanostructures are found to be room temperature ferromagnetism (RTF). The results reveal that B. subtilis shows the maximum inhibition up to 10 mm of the synthesized CuO product.
SYNTHESIS, CHARACTERIZATION AND ANTIBACTERIAL ACTIVITY OF CUO NANOPARTICLES Original Article
International Journal of Applied Pharmaceutics, 2020
Objective: The present study was done to see the effect of biologically synthesized CuO-NPs (Copperoxide nanoparticles) on the growth of bacterial strains. Methods: Physico-chemical characterization of CuO-NPs was done by UV-Vis-spectrophotometer, XRD, FE-SEM, and EDS. The disc plate diffusion assay was used to evaluate the anti-bacterial effect of CuNPs. Results: This study has shown a promising anti-bacterial activity of biosynthesized CuO-NPs at different concentrations ranging from 10 to 100 µg/ml against Escherichia coli and Staphylococcus aureus bacteria. Conclusion: Nanoparticles (NPs) are small size particles between range 1 to 100 nm which expand their physical and chemical properties due to high surface area. The present study reveals that there may be possible utilization of biosynthesized CuO NPs for the treatment of bacterial infectious disease in near future.
Synthesis, Characterization and Antibacterial Activity of Cuo Nanoparticles
International Journal of Applied Pharmaceutics, 2019
Objective: The present study was done to see the effect of biologically synthesized CuO-NPs (Copperoxide nanoparticles) on the growth of bacterial strains. Methods: Physico-chemical characterization of CuO-NPs was done by UV-Vis-spectrophotometer, XRD, FE-SEM, and EDS. The disc plate diffusion assay was used to evaluate the anti-bacterial effect of CuNPs. Results: This study has shown a promising anti-bacterial activity of biosynthesized CuO-NPs at different concentrations ranging from 10 to 100 µg/ml against Escherichia coli and Staphylococcus aureus bacteria. Conclusion: Nanoparticles (NPs) are small size particles between range 1 to 100 nm which expand their physical and chemical properties due to high surface area. The present study reveals that there may be possible utilization of biosynthesized CuO NPs for the treatment of bacterial infectious disease in near future.
Synthesis, biomedical applications, and toxicity of CuO nanoparticles
Applied Microbiology and Biotechnology
Versatile nature of copper oxide nanoparticles (CuO NPs) has made them an imperative nanomaterial being employed in nanomedicine. Various physical, chemical, and biological methodologies are in use for the preparation of CuO NPs. The physicochemical and biological properties of CuO NPs are primarily affected by their method of fabrication; therefore, selectivity of a synthetic technique is immensely important that makes these NPs appropriate for a specific biomedical application. The deliberate use of CuO NPs in biomedicine questions their biocompatible nature. For this reason, the present review has been designed to focus on the approaches employed for the synthesis of CuO NPs; their biomedical applications highlighting antimicrobial, anticancer, and antioxidant studies; and most importantly, the in vitro and in vivo toxicity associated with these NPs. This comprehensive overview of CuO NPs is unique and novel as it emphasizes on biomedical applications of CuO NPs along with its toxicological assessments which would be useful in providing core knowledge to researchers working in these domains for planning and conducting futuristic studies. Key Points • The recent methods for fabrication of CuO nanoparticles have been discussed with emphasis on green synthesis methods for different biomedical approaches. • Antibacterial, antioxidant, anticancer, antiparasitic, antidiabetic, and antiviral properties of CuO nanoparticles have been explained. • In vitro and in vivo toxicological studies of CuO nanoparticles exploited along with their respective mechanisms.
2022
This paper deals with the synthesis of copper oxide (CuO) nanoparticles by the plant-mediated method using copper acetate monohydrate and neem extract. The formation of nanoparticles was confirmed by UV-Visible spectral studies. P-XRD studies revealed that the average particle size of synthesized nanoparticles was 11.30 nm which was in good agreement with TEM results. Morphology of synthesized nanoparticles was determined by SEM which revealed that CuO nanoparticles were spherical and some were agglomerated in nature. The EDX spectrum of nanoparticles exhibited three signals one signal at 0.9 keV and other signals at ~8 keV which is due to Cu and another signal of oxygen appeared at 0.5 keV this indicated that nanoparticles of copper have been formed as copper oxide. The synthesized nanoparticles were screened for their antibacterial activity in vitro against gram-negative bacteria Escherichia coli and Pseudomonas aeruginosa by adopting the disk diffusion method. The results of antibacterial studies exhibited that CuO NPs were potential antibacterial agents.