Blood rheological changes in rodents treated with metal salts (original) (raw)

The rheological properties of blood are an important marker of changes that occur in various pathological conditions. Changes in the rheological properties of blood and the factors that determine them: number and size of blood cells, their membrane and morphological properties, serve as an indicator for early detection of many diseases.The aim of this study is to investigate the influence on the blood rheological properties of some metal compounds: cadmium acetate [Cd(CH3COO)2x2H2O], cobalt chloride (CoCl2 x 6H2O) and sodium nitrite (NaNO2), which are known to be present in the environment or daily absorbed by the body from the atmosphere or food. Plasma viscosity of rats after treatment with NaNO2 is measured too. Disturbances in the rheological properties, blood and plasma viscosity of the treated rodents are observed in comparison with a control group of non-treated rodents, depending on the type, concentration of metal salts, the animal species and the type treatment. The observ...