A subset of antibodies targeting citrullinated proteins confers protection from rheumatoid arthritis (original) (raw)
Multiplex autoantibody profiling using 'synovial proteome' microarrays identifies citrulline-modified peptides as major targets of the autoimmune response in rheumatoid arthritis
Lawrence Steinman
Arthritis Research & Therapy, 2003
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Rheumatoid Factor as a Potentiator of Anti-Citrullinated Protein Antibody-Mediated Inflammation in Rheumatoid Arthritis
Geoffrey Thiele
Arthritis & Rheumatology, 2014
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Affinity purified anti-citrullinated protein/peptide antibodies target antigens expressed in the rheumatoid joint.
Kutty Selva Nandakumar
Arthritis Res Ther , 2014
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Clinical and pathophysiological significance of the autoimmune response to citrullinated proteins in rheumatoid arthritis
Mireille Sebbag, Christian Vincent
Joint Bone Spine, 2004
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The role of anti-citrullinated protein antibodies (ACPA) in the pathogenesis of rheumatoid arthritis
Wlodzimierz Maslinski
Central-European journal of immunology, 2017
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Antibodies to several citrullinated antigens are enriched in the joints of rheumatoid arthritis patients
Karin Lundberg
Arthritis & Rheumatism, 2010
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Citrullinated proteins in rheumatoid arthritis: Crucial … but not sufficient!
Paul Tak
Arthritis & Rheumatism, 2006
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Antibodies against citrullinated proteins enhance tissue injury in experimental autoimmune arthritis
Liudmila Liudmila
The Journal of clinical investigation, 2006
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Citrullination of synovial proteins in murine models of rheumatoid arthritis
Tatsuo Senshu
Arthritis & Rheumatism, 2003
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Citrullinated proteins have increased immunogenicity and arthritogenicity and their presence in arthritic joints correlates with disease severity
Karin Lundberg
Arthritis research & therapy, 2005
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A specific anti-citrullinated protein antibody profile identifies a group of rheumatoid arthritis patients with a toll-like receptor 4-mediated disease
James Reilly
Arthritis research & therapy, 2016
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Identification of citrullinated alpha-enolase as a candidate autoantigen in rheumatoid arthritis
David Moyes, Robin Wait
Arthritis research & therapy, 2005
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Extracellular traps and PAD4 released by macrophages induce citrullination and auto-antibody production in autoimmune arthritis
Katriona Goldmann
Journal of Autoimmunity, 2019
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Specificity of Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis
Gunnar Houen
Antibodies
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Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis
Kutty Selva Nandakumar
Arthritis Research & Therapy, 2006
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Proteomic analysis of secreted proteins in early rheumatoid arthritis: anti-citrulline autoreactivity is associated with up regulation of proinflammatory cytokines
Mark Genovese
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Synovial intracellular citrullinated proteins colocalizing with peptidyl arginine deiminase as pathophysiologically relevant antigenic determinants of rheumatoid arthritis-specific humoral autoimmunity
Bart Vandekerckhove
Arthritis & Rheumatism, 2005
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Development of the anti-citrullinated protein antibody repertoire prior to the onset of rheumatoid arthritis
Azita Sohrabian
Arthritis & Rheumatism, 2011
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Citrullinated proteins in Rheumatoid Arthritis
Diego Ramírez
Reumatología Clínica (English Edition), 2011
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Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis
Kutty Selva Nandakumar
The Journal of experimental medicine, 2009
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Induction of macrophage secretion of tumor necrosis factor α through Fcγ receptor IIa engagement by rheumatoid arthritis–specific autoantibodies to citrullinated proteins complexed with fibrinogen
Mireille Sebbag, Christian Vincent
Arthritis & Rheumatism, 2008
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Citrullinated proteins are present in synovial fluids from inflammatory arthritis but not osteoarthritis
Robin Wait
Rheumatology, 2008
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Rapid Interaction Between CTLA4-Ig (Abatacept) and Synovial Macrophages from Patients with Rheumatoid Arthritis
Stefano Soldano
The Journal of Rheumatology, 2013
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Association between levels of synovial anti-citrullinated peptide antibodies and neutrophil response in patients with rheumatoid arthritis
Rodrigo Yabar Blas
European journal of immunology, 2018
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Identification of citrullinated α-enolase as a candidate autoantigen in rheumatoid arthritis
Karin Lundberg
Arthritis Research & Therapy, 2005
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Type II collagen antibody response is enriched in the synovial fluid of rheumatoid joints and directed to the same major epitopes as in collagen induced arthritis in primates and mice.
Kutty Selva Nandakumar
Arthritis Res Ther , 2014
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Multiplex Analyses of Antibodies Against Citrullinated Peptides in Individuals Prior to Development of Rheumatoid Arthritis
Per-johan Jakobsson
Arthritis & Rheumatism, 2013
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Association between anti-citrullinated alpha enolase antibodies and clinical features in a cohort of patients with rheumatoid arthritis: a pilot study
Onelia Bistoni
Reumatismo, 2018
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Antibodies to carbamylated α-enolase epitopes in rheumatoid arthritis also bind citrullinated epitopes and are largely indistinct from anti-citrullinated protein antibodies
Lars Alfredsson
Arthritis Research & Therapy, 2016
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Increased expression of Fcγ receptors II and III on macrophages of rheumatoid arthritis patients results in higher production of tumor necrosis factor α and matrix metalloproteinase
Pilar Barrera
Arthritis & Rheumatism, 2003
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Role of pro-inflammatory cytokines in rheumatoid arthritis
Ravinder Maini
Springer Seminars in Immunopathology, 1998
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