Emotional distress and health-related quality of life in patients on hemodialysis: the clinical value of COOP-WONCA charts (original) (raw)

The Impact of Anxiety and Depression on the Quality of Life of Hemodialysis Patients

Global Journal of Health Science, 2015

PURPOSE: This study was to explore the impact of anxiety and depression on the quality of life of hemodialysis patients. MATERIAL & METHODS: The sample studied consisted of 395 hemodialysis patients. Data was collected by the completion of a specially designed questionnaire for the needs of the present study which apart from socio-demographic and clinical, it also included HADS scale to assess the level of anxiety and depression as well as the scale Missoula-VITAS Quality of Life Index (MVQOLI) to assess patients’ quality of life. RESULTS: The results of this study showed that 47.8% had high anxiety levels and 38.2% had high levels of depression. The average total score of quality of life was found to be 17.14. It was also shown that the total score of quality of life presented statistically significant association with family status (p=0.007), educational level (p<0.001), the number of children (p=0.001), patients’ adherence to doctors' orders (p=0.003) and proposed diet (p=...

Anxiety and depression in maintenance hemodialysis patients: prevalence and their effects on health-related quality of life

International Urology and Nephrology

Purpose The aims of the study are to explore the prevalence and risk factors of anxiety and depression in hemodialysis (HD) patients and to study their relationship with quality of life (QOL). Methods This cross-sectional study involved 298 HD patients. Sociodemographic, clinical, and laboratory data of the patients were obtained from their records. Anxiety and depression were assessed by utilizing Hospital Anxiety and Depression Scale (HADS). In addition, QOL of the patients were evaluated by fulfilling the Kidney Disease Quality of Life-36. Results This study included 298 HD patients (male 59.1%) with a median age of 49 years. Abnormal and borderline cases of anxiety were recognized in 49.6%, 26.2% of the patients, respectively, while depression cases and borderline cases were identified in 55 and 28.2% of the patients, respectively. Percentages of females (41 and 48% vs 26.4%, respectively), and patients who were not working (92.3 and 93.9% vs 72.2%, respectively) increased signi...

Evaluation of Anxiety and Depression Disorders and the Associated Factors Among Hemodialysis Subjects

Acta Neuropsychologica, 2019

Identifying anxio-depressive disorders, evaluating their prevalence and determining the different factors that can intervene in their hap- pening to the patients suffering from hemodialysis. Transversal descriptive and analytical study over 70 patients, real- ized at the dialysis unit of the Idrissi regional hospital’s department of medicine at Kenitra, Morocco, over a period of three months starting from 27 March to 26 June 2015. The data were acquired from a survey and psychiatric evaluation scales: The scale HADS (Hospital Anxiety and Depression Scale ) to evaluate anxiety and depression and the scale of « Big Five French Inventory to evaluate the treats of personality» (BF-Fr). Average age was from 54,66±15,96 years. The seniority of the hemodialysis was on average 5,20±3,23 years. The studied traits of personality show a decrease regard to the average score of dimen- sion O (overture of sense) and of the dimension E score (extraversion) versus an evaluation of the dimension N s...

Symptoms of Anxiety and Depression Among Patients on Haemodialysis and Their Correlation with Perceived Quality of Life- a Cross Sectional Study

Journal of Evidence Based Medicine and Healthcare

BACKGROUND The prevalence of chronic kidney disease (CKD) has steadily increased over the past few decades. Multiple factors including improvements in life expectancy and increasing prevalence of comorbid illness such as hypertension and diabetes have contributed to this. Most common form of treatment in CKD patients is haemodialysis. Depression and anxiety disorders are common psychological problem among haemodialysis patients. However, there is minimal literature on the prevalence of anxiety and depressive symptoms and their impact on patient's quality of life and treatment outcomes. Quality of life (QoL) is another neglected aspect of CKD care, as the available resources are often used to address the general medical needs. The current study aims to assess the prevalence of symptoms of depression and anxiety in patients of haemodialysis and the perceived quality of life in these patients. METHODS A cross sectional observational study was done in 120 haemodialysis patients after approval from Institutional Ethics Committee and after getting informed consent from patients. The study was done in the dialysis unit under Department of Nephrology, Travancore Medical College, Kollam. Patients were screened by a semi-structured questionnaire which includes the patients' socio-demographic data. Hospital Anxiety and Depression Scale (HADS) was used to assess severity of anxiety and depressive symptoms. The Quality of Life (QoL) was assessed using Kidney Disease Quality of Life questionnaire (KDQOL-36™), with higher scores indicating better quality of life. RESULTS The prevalence of anxiety symptoms in study sample is 64.2% and prevalence of depressive symptoms in study sample was found to be 37.5% which was significantly high. There was statistically significant association between anxiety and depressive symptoms with age of patients, gender, duration of dialysis and complication during dialysis. The five domains of KDQOL showed that mean scores of QoL in areas of mental and physical health along with effect of kidney disease on life and burden of having kidney disease were less indicating poor quality of life. Anxiety and depression were negatively correlated to all the domains of KDQOL indicating that anxiety and depressive symptoms worsened quality of life of dialysis patients. CONCLUSIONS Depressive and anxiety symptoms are significantly prevalent in patients undergoing maintenance haemodialysis which usually go un-addressed. Older patients and females were more at risk of developing depressive and anxiety symptoms. Longer periods of dialysis and complications during dialysis were also important contributors to depressive and anxiety symptoms. Quality of Life was poor in patients on dialysis, and symptoms of anxiety and depressive negatively impacted quality of life.

Course of Depression and Anxiety Diagnosis in Patients Treated with Hemodialysis

Clinical Journal of the American Society of Nephrology, 2008

Background and objectives: There is growing identification of the need to seriously study the psychiatric presentations of end-stage renal disease patients treated with hemodialysis. This study reports on the course of depression and anxiety diagnoses and their impact on quality of life and health status. Design, setting, participants, & measurements: The 16-mo course of psychiatric diagnoses in 50 end-stage renal disease patients treated with hemodialysis was measured by structured clinical interview. Results: Three different pathways were identified: one subset of patients not having a psychiatric diagnosis at either baseline or 16-mo follow-up (68% for depression, 51% for anxiety), one group having an intermittent course (21% for depression, 34% for anxiety), and one group having a persistent course (11% for depression, 15% for anxiety), with diagnoses at both time 1 and time 2. For depression, the people with the persistent course showed marked decreases in quality of life and self-reported health status compared with the nondepressed and intermittently depressed cohorts. The most powerful predictor of depression at time 2 is degree of depressive affect at time 1(P < 0.05). Conclusions: Patients at risk for short-and long-term complications of depression can be potentially identified by high levels of depressive affect even at a single time point. As nearly 20% of the sample had chronic depression or anxiety, identifying a psychiatric diagnosis in hemodialysis patients and then offering treatment are important because, in the absence of intervention, psychiatric disorders are likely to persist in a substantial proportion of patients.

Correlates of symptoms of depression and anxiety in chronic hemodialysis patients

General Hospital Psychiatry, 2010

Little is known about the demographic, clinical and laboratory variables which may be correlated with symptoms of depression and anxiety in hemodialysis (HD) patients. The present study aimed at evaluating such correlation in HD patients treated at a single HD center in a Mediterranean country. Methods: Eighty HD patients were assessed for depression and anxiety with the Beck Depression Inventory (BDI) and the Hamilton Anxiety Rating Scale (HARS). The scores of BDI and HARS were correlated with demographic, clinical and laboratory variables. Results: Based on the Beck Depression Inventory, 38 patients had no symptoms of depression and 42 had symptoms of depression. Based on the HARS, three patients had no symptoms of anxiety and 38 had mild symptoms of anxiety, whereas moderate or severe symptoms of anxiety were present in 39 patients. In univariate analysis, BDI score correlated significantly with age, the Charlson Comorbidity Index, SF-36 Vitality Subscale, Mini-Mental Status Examination, creatinine, albumin, plasma 25-hydroxy vitamin D and interleukin-6 (IL-6) levels. HARS score correlated significantly with age, Charlson Comorbidity Index, SF-36 Vitality Subscale and parathyroid hormone (PTH) levels. In the multivariate analysis, a direct and an inverse correlation between BDI and IL-6 [P=.042, OR=1.31 (95% CI=1.01-1.71)] and creatinine [P=.050, OR=0.73 (95% CI=0.54-1.00)] was observed. With regard to HARS, only a direct correlation with Charlson Comorbidity Index [Pb.001, OR=1.55 (95% CI=1.22-1.96)] was found. Conclusion: Although numerous demographic, clinical and laboratory variables correlated with BDI and HARS in univariate analysis, the multivariate regression analysis showed only a direct correlation between BDI and IL-6 [P=.042, OR=1.31 (95% CI=1.01-1.71)] and an inverse correlation between BDI and creatinine [P=.050, OR=0.73 (95% CI=0.54-1.00)] and a direct correlation between HARS and the Charlson Comorbidity Index [Pb.001, OR=1.55 (95% CI=1.22-1.96)].

Depression and anxiety among patients with chronic kidney disease receiving hemodialysis

2018

Introduction: Depression and anxiety are among the most common comorbid illnesses in people with end-stage renal disease. The current study aimed to assess the actual pattern of symptoms of depression and anxiety in the hemodialysis population in Qazvin. Methods: For this purpose, 80 individuals (40 hemodialysis patients and 40 individuals as the control group) have participated in this study. All participants completed Beck Depression Inventory and Cattell Anxiety Inventory. Additionally, clinical status, socioeconomic and demographic variables of patients have been collected and analyzed by appropriate statistical methods (independent T-test and chi-square test). Results: In examining the variables of depression in terms of severe and mild depression, there have been 14 hemodialysis patients (35%) versus 34 (85%) individuals from the control group, in terms of moderate depression-severe index there has been 26 (65%) versus 6 (15%). Regarding the anxiety variable in terms of the ma...

Psychosocial Factors and Health-Related Quality of Life in Hemodialysis Patients

Quality of Life Research, 2005

Several sociodemographic and clinical variables are known to influence the health-related quality of life (HRQOL) of patients with kidney disease, yet the relationship between psychological factors and the HRQOL measured by the Kidney Disease Quality of Life Short-Form (KDQOL-SF) is incompletely understood. The objective of this study was to examine the relationship between psychosocial status (depressive symptoms, trait anxiety, and social support) and KDQOL-SF scales in hemodialysis (HD) patients by controlling the effects of sociodemographic and clinical variables. The HRQOL of 194 patients from 43 dialysis centers in Spain was assessed by completing the KDQOL-SF, and evaluating depressive symptoms (Cognitive Depression Index), trait anxiety (Trait Anxiety Inventory) and degree of social support (Scale of Perceived Social Support). We also recorded several sociodemographic and clinical variables. Two regression models were estimated for each of the 19 scales in the KDQOL-SF. In the first model, we only included sociodemographic and clinical-factors, while the second model also took into consideration psychosocial variables. These last factors (trait anxiety and depressive symptoms, not social support) were found to increase the proportion of explained variability, with highest standardized regression coefficients observed for most KDQOL-SF scales. Depressive symptoms were related to a poor HRQOL when there was a strong physical component, while trait anxiety was mainly related to emotional upset and social relationships. We were able to conclude that trait anxiety and depressive symptoms are strongly associated with the HRQOL assessed by the KDQOL-SF in HD patients. The effects of these factors should therefore be considered when evaluating the quality of life of this type of patient.

Level of Depression and Anxiety on Quality of Life Among Patients Undergoing Hemodialysis [Letter]

International Journal of General Medicine, 2023

We have read the cross-sectional study conducted by Sameeha Alshelleh et al 1 with great interest. We appreciate the author for sharing her experience for the promotion of psychological health among the patients of Hemodialysis. However, we would like to convey our perspective on this study. Spirituality is one of the fundamental roots of mental well-being. It provides the inner peace and feeling of well being which help the patient to cope with the burden of disease. Studies have shown that strong belief among the hemodialysis patient is correlated with decreased perception of illness burden and increased perception of social support. 2 So religious feelings should be added to this research as they are originally discussed under the domain of WHO-QOL BREF to assess the level of depression among the patients. The psychological health of a patient also markedly depends upon the intellectual power of a human. Having good intellect is one of the 8 dimensions of mental well-being 3 Assessment of patient intellect through different innovative ways could give a powerful impact to this study. The authors declare their research to be translated into Arabic and the findings retranslated back to English, this can potentially create a concept called loss in translation, or interpretation bias; the translator or the questioner portrays the questions in such a manner which reflects his own understanding of the survey rather than the patient's own understanding level.This can affect the more meaningful association of true literacy with quality of life, depression and anxiety. In the discussion, it has been highlighted that higher levels of depression and GAD have been observed more among females than male. However, women under the selected age group of this research are more or less near to her menopausal age. Menopause itself has a positive relation with depression and GAD. 4 This could be one of the explanations of higher incidence of depression and GAD among females. It also should be asked if the female patients are on their periods, as depression is common during menses. Lastly, the patients were only asked for any previous history of diagnosed psychological disorders, this inclusion criteria misses out many undiagnosed psychological and mood disorders very common in countries with low awareness, a research focusing on depression and anxiety co-relations needs a more rigorous psychological screening method to rule out previously undetected mood and psychological disorders.