Multivalent structure of an αβT cell receptor (original) (raw)

Molecular architecture of the αβ T cell receptor–CD3 complex

Proc Natl Acad Sci USA, 2014

Physical and Functional Bivalency Observed Among TCR/CD3 Complexes Isolated from Primary T Cells

The Journal of Immunology, 2011

Stoichiometry of the T cell antigen receptor complex: each TCR/CD3 complex contains one TCR alpha, one TCR beta, and two CD3 epsilon chains

Kelly Kearse

1994

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The structural basis of αβ T‐lineage immune recognition: TCR docking topologies, mechanotransduction, and co‐receptor function

Jia-huai Wang

Immunological Reviews, 2012

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Pairwise, cooperative and inhibitory interactions describe the assembly and probable structure of the T-cell antigen receptor

N. Manolios

The EMBO Journal, 1991

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Monomeric TCR-CD3 Complexes Drive T-Cell Antigen Recognition

Johannes Huppa

Biophysical Journal, 2018

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Stoichiometry of the T cell antigen receptor (TCR) complex: each TCR/CD3 complex contains one TCR alpha, one TCR beta, and two CD3 epsilon chains

Kelly Kearse

Journal of Experimental Medicine, 1994

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Atomic structure of an alpha beta T cell receptor (TCR) heterodimer in complex with an anti-TCR Fab fragment derived from a mitogenic antibody

Robert Sweet

The EMBO Journal, 1998

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T cell receptor CDR3 loops influence αβ pairing

Stephen Holland

2010

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Structural Studies on the αβ T-cell Receptor

James McCluskey

IUBMB Life (International Union of Biochemistry and Molecular Biology: Life), 2005

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Structure and specificity of T cell receptor γ/δ on major histocompatibility complex antigen-specific CD3+, CD4-, CD8- T lymphocytes

Melissa Damschroder

Journal of Experimental Medicine

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αβ T Cell Receptors that Do Not Undergo Major Histocompatibility Complex-Specific Thymic Selection Possess Antibody-like Recognition Specificities

Changwan Hong

Immunity, 2012

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Supplemental Data Antigen Ligation Triggers a Conformational Change within the Constant Domain of the αβ T Cell Receptor

Chih Liu

2000

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Biochemical Differences in the αβ T Cell Receptor·CD3 Surface Complex between CD8+ and CD4+ Human Mature T Lymphocytes

Balbino Alarcón

Journal of Biological Chemistry, 2004

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A conserved αβ transmembrane interface forms the core of a compact T-cell receptor–CD3 structure within the membrane

Soohyung Park

Proceedings of the National Academy of Sciences of the United States of America, 2016

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Partial inefficiency of T cell receptors γ/δ composed of a heavy (55-kD) γ chain to mediate cell activation upon binding to specific monoclonal antibodies

Giuseppe Tambussi

International Journal of …, 1989

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T-cell receptor structure and TCR complexes

Christopher Garcia

Current Opinion in Structural Biology, 1997

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Loss of N-terminal Charged Residues of Mouse CD3ɛ Chains Generates Isoforms Modulating Antigen T Cell Receptor-mediated Signals and T Cell Receptor-CD3 Interactions

María José Feito

Journal of Biological Chemistry, 2007

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The TCR/CD3 complex: molecular interactions in a changing structure

María José Feito

Archivum immunologiae et therapiae experimentalis, 2002

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Role of 2c T Cell Receptor Residues in the Binding of Self-And Allo-Major Histocompatibility Complexes

Mark Daniels

Journal of Experimental Medicine, 2000

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A Single T Cell Receptor Bound to Major Histocompatibility Complex Class I and Class II Glycoproteins Reveals Switchable TCR Conformers

Lei Yin

Immunity, 2011

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T Cell Receptor Complexes Containing FcERI 3, Homodimers in Lieu of CD3~" and CD3v/Components: A Novel Isoform Expressed on Large Granular Lymphocytes

Sheena Abraham

1992

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Conserved T-cell receptor class II major histocompatibility complex contact detected in a T-lymphocyte population

Ming-Zong Lai

Immunology, 1998

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Expression and function of a variant T cell receptor complex lacking CD3-gamma

Antonio Arnaiz-Villena

Journal of Experimental Medicine, 1991

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How the T Cell Receptor Sees Antigen—A Structural View

Erin Adams

Cell, 2005

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T-cell receptors: Feeling out the complex

David Margulies

Current Biology, 1997

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Monomeric TCRs drive T cell antigen recognition

Hannes Stockinger

Nature Immunology, 2018

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Full Activation of the T Cell Receptor Requires Both Clustering and Conformational Changes at CD3

Balbino Alarcón

Immunity, 2007

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Distinct CDR3 conformations in TCRs determine the level of cross-reactivity for diverse antigens, but not the docking orientation

Jennifer Stone

The Journal of …, 2008

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T cell receptor interactions with syngeneic and allogeneic ligands: Affinity measurements and crystallization

Luc Teyton

Proceedings of the National Academy of Sciences, 1997

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Crystal structure of the human T cell receptor CD3 heterodimer complexed to the therapeutic mAb OKT3

Nicole Mifsud

Proceedings of the National Academy of Sciences, 2004

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Molecular modeling of a T-cell receptor bound to a major histocompatibility complex molecule: Implications for T-cell recognition

E. Horjales, Juan Almagro

Protein Science, 1995

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Multivalent structure of an αβT cell receptor (original) (raw)

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