Pharmacology of recombinant γ-aminobutyric acidAreceptors rendered diazepam-insensitive by point-mutated α-subunits (original) (raw)
Cloning and characterization of the human GABAA receptor α4 subunit: identification of a unique diazepam-insensitive binding site
Juergen Drewe
European Journal of Pharmacology: Molecular Pharmacology, 1995
View PDFchevron_right
Diazepam enhancement of GABA-gated currents in binary and ternary GABA A receptors
Ricardo Granja
Journal of Molecular Neuroscience, 1997
View PDFchevron_right
The γ3-subunit of the GABAA-receptor confers sensitivity to benzodiazepine receptor ligands
Frederic Knoflach
FEBS Letters, 1991
View PDFchevron_right
Anomalous rectifying properties of `diazepam-insensitive' GABA A receptors
Ricardo Granja
European Journal of Pharmacology, 1998
View PDFchevron_right
Selective labelling of diazepam-insensitive GABA A receptors in vivo using [ 3 H]Ro 15-4513
Thomas Rosahl
British Journal of Pharmacology, 2005
View PDFchevron_right
Structural Elements of the γ-Aminobutyric Acid Type A Receptor Conferring Subtype Selectivity for Benzodiazepine Site Ligands
François BESNARD
Journal of Biological Chemistry, 1999
View PDFchevron_right
Structural Elements of the gamma -Aminobutyric Acid Type A Receptor Conferring Subtype Selectivity for Benzodiazepine Site Ligands
Pascal George
Journal of Biological Chemistry, 1999
View PDFchevron_right
Inhibition of γ-aminobutyric acid stimulated [3H]diazepam binding by benzodiazepine receptor ligands
Phil Skolnick
Biochemical Pharmacology, 1981
View PDFchevron_right
GABAA Receptor α Subunits Differentially Contribute to Diazepam Tolerance after Chronic Treatment
Henrik Hansen
PLoS ONE, 2012
View PDFchevron_right
Structural Determinants of Benzodiazepine Allosteric Regulation of GABAAReceptor Currents
Dorothy Jones Davis
The Journal of Neuroscience, 2005
View PDFchevron_right
Triazolam is more efficacious than diazepam in a broad spectrum of recombinant GABAA receptors
Stefano Vicini
European Journal of Pharmacology: Molecular Pharmacology, 1993
View PDFchevron_right
Actions of two GABAA receptor benzodiazepine-site ligands that are mediated via non-γ2-dependent modulation
Holger Rabe, Hartmut Lüddens
European Journal of Pharmacology, 2011
View PDFchevron_right
GABA antagonists differentiate between recombinant GABAA/benzodiazepine receptor subtypes
Hartmut Lüddens
The Journal of Neuroscience, 1995
View PDFchevron_right
Enhancement of γ-Aminobutyric Acid Binding by Quazepam, a Benzodiazepine Derivative with Preferential Affinity for Type I Benzodiazepine Receptors
Valeria Nurchi
Journal of Neurochemistry, 2006
View PDFchevron_right
Biological function of GABAA/benzodiazepine receptor heterogeneity
Hartmut Lüddens
Journal of Psychiatric Research, 1995
View PDFchevron_right
Kucken AM, Wagner DA, Ward PR, Teissere JA, Boileau AJ, Czajkowski C (2000) "Identification of benzodiazepine binding site residues in the gamma2 subunit of the GABA(A) receptor" Molecular Pharmacology 57:932-9.
Jeremy Alden Teissere
View PDFchevron_right
erratum: Benzodiazepine actions mediated by specific γ-aminobutyric acidA receptor subtypes
Jack Benson
Nature, 2000
View PDFchevron_right
Estimating the efficiency of benzodiazepines on GABA A receptors comprising γ1 or γ2 subunits
Sophia Khom
British Journal of Pharmacology, 2008
View PDFchevron_right
Sh-I-048A, an in vitro non-selective super-agonist at the benzodiazepine site of GABAA receptors: The approximated activation of receptor subtypes may explain behavioral effects
Bojan Markovic
Brain Research, 2014
View PDFchevron_right
An Updated Unified Pharmacophore Model of the Benzodiazepine Binding Site on γ-Aminobutyric Acida Receptors: Correlation with Comparative Models
James Cook
Current Medicinal Chemistry, 2007
View PDFchevron_right
The novel anxiolytic ELB139 displays selectivity to recombinant GABAA receptors different from diazepam
Holger Rabe, Hartmut Lüddens
Neuropharmacology, 2007
View PDFchevron_right
Structural Mechanisms Underlying Benzodiazepine Modulation of the GABAA Receptor
Susan Hanson
Journal of Neuroscience, 2008
View PDFchevron_right
Allosteric uncoupling and up-regulation of benzodiazepine and GABA recognition sites following chronic diazepam treatment of HEK 293 cells stably transfected with α 1 β 2 γ 2S subunits of GABA A receptors
Josipa Vlainic
Naunyn-schmiedebergs Archives of Pharmacology, 2007
View PDFchevron_right
Benzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptors
Jack Benson
Proceedings of the National Academy of Sciences, 1995
View PDFchevron_right